Induction of hepatitis C virus-specific cytotoxic T and B cell responses by dendritic cells expressing a modified antigen targeting receptor

World Journal of Gastroenterology

Volumn 11, Issue 4, 2005, Pages 557-560

  Wang, Quan Chu ^a   Feng, Zhi Hua ^a   Zhou, Yong Xing ^a   Nie, Qing He ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cytotoxic T lymphocytes; Dendritic cell vaccine; Hepatitis C virus

Indexed keywords

COMPLEMENTARY DNA; DENDRITIC CELL VACCINE; HEPATITIS B CORE ANTIGEN; HEPATITIS C ANTIBODY; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G; LACTATE DEHYDROGENASE; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; BIOASSAY; CANCER INHIBITION; CELL ACTIVITY; CELL STRAIN; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXIC LYMPHOCYTE; DENDRITIC CELL; DRUG RECEPTOR BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPRESSION VECTOR; HEPATITIS C VIRUS; IMMUNE RESPONSE; IMMUNIZATION; MOUSE; MOUSE STRAIN; NONHUMAN; PLASMID; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SURVIVAL RATE; T LYMPHOCYTE;

EID: 13244262918     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i4.557     Document Type: Article

References (29)

1. Brady MT, MacDonald AJ, Rowan AG, Mills KH. Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes. Eur J Immunol 2003; 33: 3448-3457
2. Jinushi M, Takehara T, Tatsumi T, Kanto T, Groh V, Spies T, Suzuki T, Miyagi T, Hayashi N. Autocrine/paracrine IL-15 that is required for type I IFN-mediated dendritic cell expression of MHC class I-related chain A and B is impaired in hepatitis C virus infection. J Immunol 2003; 171: 5423-5429
3. Rollier C, Drexhage JA, Verstrepen BE, Verschoor EJ, Bontrop RE, Koopman G, Heeney JL. Chronic hepatitis C virus infection established and maintained in chimpanzees independent of dendritic cell impairment. Hepatology 2003; 38: 851-858
4. Sarobe P, Lasarte JJ, Zabaleta A, Arribillaga L, Arina A, Melero I, Borras-Cuesta F, Prieto J. Hepatitis C virus structural proteins impair dendritic cell maturation and inhibit in vivo induction of cellular immune responses. J Virol 2003; 77: 10862-10871
5. Dolganiuc A, Kodys K, Kopasz A, Marshall C, Do T, Romics L Jr, Mandrekar P, Zapp M, Szabo G. Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation. J Immunol 2003; 170: 5615-5624
6. Gardner JP, Durso RJ, Arrigale RR, Donovan GP, Maddon PJ, Dragic T, Olson WC. L-SIGN (CD 209L) is a fiver-specific capture receptor for hepatitis C virus. Proc Natl Acad Sci USA 2003; 100 4498-4503
7. Pohlmann S, Zhang J, Baribaud F, Chen Z, Leslie GJ, Lin G, Granelli-Piperno A, Doms RW, Rice CM, McKeating JA. Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR. J Virol 2003; 77: 4070-4080
8. Lozach PY, Lortat-Jacob H, de Lacroix de Lavalette A, Staropoli I, Foung S, Amara A, Houles C, Fieschi F, Schwartz O, Virelizier JL, Arenzana-Seisdedos F, Altmeyer R. DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2. J Biol Chem 2003; 278: 20358-20366
9. Jinushi M, Takehara T, Kanto T, Tatsumi T, Groh V, Spies T, Miyagi T, Suzuki T, Sasaki Y, Hayashi N. Critical role of MHC class I-related chain A and B expression on IFN-alpha-stimulated dendritic cells in NK cell activation: impairment in chronic hepatitis C virus infection. J Immunol 2003; 170: 1249-1256
10. Laporte J, Bain C, Maurel P, Inchauspe G, Agut H, Cahour A. Differential distribution and internal translation efficiency of hepatitis C virus quasispecies present in dendritic and liver cells. Blood 2003; 101: 52-57
11. Beckebaum S, Cicinnati VR, Gerken G. DNA-based immunotherapy: potential for treatment of chronic viral hepatitis? Rev Med Virol 2002; 12: 297-319
12. Sarobe P, Lasarte JJ, Casares N, Lopez-Diaz de Cerio A, Baixeras E, Labarga P, Garcia N, Borras-Cuesta F, Prieto J. Abnormal priming of CD4 (+) T cells by dendritic cells expressing hepatitis C virus core and E1 proteins. J Virol 2002; 76: 5062-5070
13. Lechmann M, Murata K, Satoi J, Vergalla J, Baumert TF, Liang TJ. Hepatitis C virus-like particles induce virus-specific humoral and cellular immune responses in mice. Hepatology 2001; 34: 417-423
14. Auffermann-Gretzinger S, Keeffe EB, Levy S. Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection. Blood 2001; 97: 3171-3176
15. Ito A, Kanto T, Kuzushita N, Tatsumi T, Sugimoto Y, Miyagi T, Takehara T, Katayama K, Mochizuki K, Hiramatsu N, Kasahara A, Yoshiya I, Sasaki Y, Hori M, Hayashi N. Generation of hepatitis C virus-specific cytotoxic T lymphocytes from healthy individuals with peptide-pulsed dendritic cells. J Gastroenterol Hepatol 2001; 16 309-316
16. Bain C, Fatmi A, Zoulim F, Zarski JP, Trepo C, Inchauspe G. Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection. Gastroenterology 2001; 120: 512-524
17. Notas G, Xidakis C, Valatas V, Kouroumalis A, Kouroumalis E. Levels of circulating endothelin-1 and nitrates/nitrites in patients with virus-related hepatocellular carcinoma. J Viral Hepat 2001; 8: 63-69
18. Beckebaum S, Cicinnati VR, Zhang X, Ferencik S, Frilling A, Grosse-Wilde H, Broelsch CE, Gerken G. Hepatitis B virus-induced defect of monocyte-derived dendritic cells leads to impaired T helper type 1 response in vitro: mechanisms for viral immune escape. Immunology 2003; 109: 487-495
19. Lohr HF, Pingel S, Bocher WO, Bernhard H, Herzog-Hauff S, Rose-John S, Galle PR. Reduced virus specific T helper cell induction by autologous dendritic cells in patients with chronic hepatitis B-restoration by exogenous interleukin-12. Clin Exp Immunol 2002; 130: 107-114
20. Horiike N, Fazle-Akbar S, Ninomiya T, Abe M, Michitaka K, Onji M. Activation and maturation of antigen-presenting dendritic cells during vaccine therapy in patients with chronic hepatitis due to hepatitis B virus. Hepatol Res 2002; 23: 38-47
21. Li MS, Yuan AL, Zhang WD, Chen XQ, Tian XH, Piao YJ. Immune response induced by dendritic cells induce apoptosis and inhibit proliferation of tumor cells. Shijie Huaren Xiaohua Zazhi 2000; 8: 56-58
22. Chen HB, Zhang JK, Huang ZL, Sun JL, Zhou YQ. Effects of cytokines on dendritic cells against human hepatoma cell line. Shijie Huaren Xiaohua Zazhi 1999; 7: 191-193
23. Zhang JK, Chen HB, Sun JL, Zhou YQ. Effect of dendritic cells on LPAK cells induced at different times in killing hepatoma cells. Shijie Huaren Xiaohua Zazhi 1999; 7: 673-675
24. Zhang J, Zhang JK, Zhuo SH, Chen HB. Effect of a cancer vaccine prepared by fusions of hepatocarcinoma cells with dendritic cells. World J Gastroenterol 2001; 7: 690-694
25. Luo ZB, Luo YH, Lu R, Jin HY, Zhang PB, Xu CP. Immunohistochemical study on dendritic cells in gastric mucosa of patients with gastric cancer and precancerous lesions. Shijie Huaren Xiaohua Zazhi 2000; 8: 400-402
26. Li MS, Yuan AL, Zhang WD, Chen XQ, Zhang YL, Zhou DY. Functional changes of dendritic cells derived from PBMC of patients with colorectal neoplasms. Shijie Huaren Xiaohua Zazhi 1999; 7: 429
27. Xing LH, Wang FS, Liu MX, Zhu CL. Dendritic cells and liver diseases. Shijie Huaren Xiaohua Zazhi 2000; 8: 1276-1279
28. Wang QC, Feng ZH, Zhou YX, Nie QH, Hao CQ, Wang JP. Comparative research of dendritic cells cultured from mice bone marrow with different ways. Shijie Huaren Xiaohua Zazhi 2003; 11: 219-223
29. Xing LH, Wang FS, Liu MX, Zhu CL, Li HW, Lei ZY, Wang HF. Dendritic cells cultured from PBMC of patients with chronic hepatitis B viral. Shijie Huaren Xiaohua Zazhi 2001; 9: 591-593