Prevention of venous thromboembolism in orthopedic surgery with vitamin K antagonists: A meta-analysis

Journal of Thrombosis and Haemostasis

Volumn 2, Issue 7, 2004, Pages 1058-1070

  Mismetti, P ^a   Laporte, Silvy ^a   Zufferey, P ^a   Epinat, M ^a   Decousus, H ^a   Cucherat, M ^b  

^a SERVICE DE NEUROLOGIE   (France)

^b Laennec Rockefeller University   (France)

Author keywords

Meta analysis; Orthopedic surgery; Vitamin K antagonists

Indexed keywords

ACENOCOUMAROL; ACETYLSALICYLIC ACID; ANTIVITAMIN K; ARDEPARIN; DALTEPARIN; DANAPAROID; DEXTRAN 40; DEXTRAN 70; DICOUMAROL; ENOXAPARIN; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; NADROPARIN; PHENINDIONE; PLACEBO; REVIPARIN; SUDOXICAM; TINZAPARIN; WARFARIN;

ARTICLE; BLEEDING; CLINICAL TRIAL; COMPUTER ANALYSIS; DEEP VEIN THROMBOSIS; DRUG EFFICACY; DRUG FATALITY; HEMATOMA; HIP SURGERY; HUMAN; LUNG EMBOLISM; MEDICAL ASSESSMENT; MEDICAL LITERATURE; MEDLINE; META ANALYSIS; ORTHOPEDIC SURGERY; PATIENT SELECTION; PRIORITY JOURNAL; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; RISK REDUCTION; SURGICAL PATIENT; SYSTEMATIC REVIEW; TOTAL HIP PROSTHESIS; TOTAL KNEE REPLACEMENT; TREATMENT OUTCOME; VENOUS THROMBOEMBOLISM;

FIBRINOLYTIC AGENTS; HEMORRHAGE; HUMANS; ORTHOPEDIC PROCEDURES; POSTOPERATIVE COMPLICATIONS; RANDOMIZED CONTROLLED TRIALS; SURVIVAL RATE; THERAPEUTIC EQUIVALENCY; THROMBOEMBOLISM; VENOUS THROMBOSIS; VITAMIN K;

EID: 13244260755     PISSN: 15387933     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2004.00757.x     Document Type: Article

References (61)

1. Geerts WH, Heit JA, Clagett GP, Pineo GF, Colwell CW, Anderson FA, Wheeler HB. Prevention of venous thromboembolism. Sixth ACCP Consensus Conference on antithrombotic therapy. Chest 2001; 119 (Suppl.): 132S-75S.
2. Nicolaides AN. Prevention of venous thromboembolism. European Consensus Statement. Int Angiol 1997; 16: 3-38.
3. Hirsh J, Dalen JE, Anderson DR, Poller L, Bussey H, Ansell J, Deykin D. Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Sixth ACCP Consensus Conference on antithrombotic therapy. Chest 2001; 119 (Suppl.): 8S-21S.
4. Freedman KB, Brookenthal KR, Fitzgerald RH, Williams S, Lonner JH. A meta-analysis of thromboembolic prophylaxis following elective total hip arthroplasty. J Bone Joint Surg Am 2000; 82-A 929-38.
5. Mohr DN, Silverstein MD, Murtaugh PA, Harrison JM. Prophylactic agents for venous thrombosis in elective hip surgery. Meta-analysis of studies using venographic assessment. Arch Intern Med 1993; 153: 2221-8.
6. Imperiale TF, Speroff T. A meta-analysis of methods to prevent venous thromboembolism following total hip replacement. JAMA 1994; 271: 1780-5.
7. Palmer AJ, Koppenhagen K, Kirchhof B, Weber U, Bergemann R. Efficacy and safety of low molecular weight heparin, unfractionated heparin and warfarin for thrombo-embolism prophylaxis in orthopaedic surgery: a meta-analysis of randomized clinical trials. Haemostasis 1997; 27: 75-84.
8. Howard AW, Aaron SD. Low molecular weight heparin decreases proximal and distal venous thrombosis following total knee arthroplasty. A meta-analysis of randomized trials. Thromb Haemost 1998; 79 902-6.
9. Brookenthal KR, Freedman KB, Lotke PA, Fitzgerald RH, Lonner JH. A meta-analysis of thromboembolic prophylaxis in total knee arthroplasty. J Arthroplasty 2001; 16: 293-300.
10. Westrich GH, Haas S, Mosca P, Peterson M. Meta-analysis of thromboembolic prophylaxis after total knee arthroplasty. J Bone Joint Surg Br 2000; 82-B: 795-800.
11. Jüni P, Altman DG, Egger M. Assessing the quality of controlled clinical trials. Br Med J 2001; 323: 42-6.
12. Cucherat M. Méta-analyse des essais thérapeutiques. Evaluation et Statistique. Paris: Masson Ed, 1997.
13. Cucherat M, Boissel JP, Leizorovicz A, Haugh MC. EasyMA: a program for the meta-analysis of clinical trials. Comp Meth Prog Biomed 1997; 53: 187-90.
14. Cucherat M. EasyMA Software Version 2000. http://www.spc.univ-lyonl.fr/~mcu/easyma
15. Borgström S, Greitz T, van der Linden W, Molin J, Rudics I. Anticoagulant prophylaxis of venous thrombosis in patients with fractured neck of the femur. A controlled trial using venous phlebography. Acta Chir Scand 1965; 129: 500-8.
16. Eskeland G, Solheim K, Skjörten F. Anticoagulant prophylaxis, thromboembolism and mortality in elderly patients with hip fractures. A controlled clinical trial. Acta Chir Scand 1966; 131: 16-29.
17. Myrhe HO, Holen A. Tromboseprofylakse. Dextran eller warfarinnatrium? Nordisk Med 1969; 82: 1534-8.
18. Hamilton HW, Crawford JS, Gardiner JH, Wiley AM. Venous thrombosis in patients with fracture of the upper end of the femur. A phlebographic study of the effect of prophylactic anticoagulation. J Bone Joint Surg Br 1970; 52: 268-89.
19. Pinto DJ. Controlled trial of an anticoagulant (warfarin sodium) in the prevention of venous thrombosis following hip surgery. Br J Surg 1970; 57: 349-52.
20. 125I fibrinogen and the prevention of venous thrombosis. Arch Surg 1973; 107: 803-6.
21. Morris GK, Mitchell JRA. Warfarin sodium in prevention of deep venous thrombosis and pulmonary embolism in patients with fractured neck of femur. Lancet 1976; 2: 869-72.
22. Powers PJ, Gent M, Jay RM, Julian DH, Turpie AGG, Levine M, Hirsh J. A randomized trial of less intense postoperative warfarin or aspirin therapy in the prevention of venous thromboembolism after surgery for fractured hip. Arch Intern Med 1989; 149: 771-4.
23. Harris WH, Salzman EW, DeSanctis RW, Coutts RD. Prevention of venous thromboembolism following total hip replacement. Warfarin vs dextran 40. JAMA 1972; 220: 1319-22.
24. Barber HM, Galasko CSB, Sutton RA, Feil EJ, Edwards DH, Haynes DW, Bentley G. A comparative study of dextran-70, warfarin and low-dose heparin for the prophylaxis of thrombo-embolism following total hip replacement. Postgrad Med J 1977; 53: 130-3.
25. Francis CW, Marder VJ, McCollister E, Yaukoolbodi S. Two-step warfarin therapy. Prevention of postoperative venous thrombosis without excessive bleeding. JAMA 1983; 249: 374-9.
26. Lotke PA, Palevsky H, Keenan AM, Meranze S, Steinberg ME, Ecker ML, Kelley MA. Aspirin and warfarin for thromboembolic disease after total joint arthroplasty. Clin Orthop 1996; 324: 251-8.
27. Paiement G, Wessinger SJ, Waltman AC, Harris WH. Low-dose warfarin versus external pneumatic compression for prophylaxis against venous thromboembolism following total hip replacement. J Arthroplasty 1987; 2: 23-6.
28. Bailey JP, Kruger MP, Solano FX, Zajko AB, Rubash HE. Prospective randomized trial of sequential compression devices vs lowdose warfarin for deep venous thrombosis prophylaxis in total hip arthroplasty. J Arthroplasty 1991; 6 (Suppl.): S29-35.
29. Kaempffe FA, Lifeso RM, Meinking C. Intermittent pneumatic compression versus coumadin. Prevention of deep vein thrombosis in lower-extremity total joint arthroplasty. Clin Orthop 1991; 269 89-97.
30. Francis CW, Pellegrini VD, Marder VJ, Totterman S, Harris CM, Gabriel R, Azodo MV, Leibert KM. Comparison of warfarin and external pneumatic compression in prevention of venous thrombosis after total hip replacement. JAMA 1992; 267: 2911-5.
31. van Geloven F, Wittebol P, Sixma JJ. Comparison of postoperative coumarin, dextran 40 and subcutaneous heparin in the prevention of postoperative deep vein thrombosis. Acta Med Scand 1977; 202: 367-72.
32. Hull R, Raskob G, Pineo G, Rosenbloom D, Evans W, Mallory T, Anquist K, Smith F, Hughes G, Green D, Elliott CG, Parju A, Brant R. A comparison of subcutaneous low-molecular-weight heparin with warfarin sodium for prophylaxis against deep-vein thrombosis after hip or knee implantation. N Engl J Med 1993; 329: 1370-6.
33. The RD Heparin Arthroplasty Group. RD Heparin compared with warfarin for prevention of venous thromboembolic disease following total hip or knee arthroplasty. J Bone Joint Surg Am 1994; 76-A: 1174-85.
34. Hamulyak K, Lensing AWA, van der Meer J, Smid WM, van Ooy A, Hoek JA for the Fraxiparine Oral Anticoagulant Study Group. Subcutaneous low-molecular weight heparin or oral anticoagulants for the prevention of deep-vein thrombosis in elective hip and knee replacement? Thromb Haemost 1994; 74: 1428-31.
35. Leclerc JR, Geers WH, Desjardins L, Laflamme GH, l'Espérance B, Demers C, Kassis J, Cruickshank M, Whitman L, Delorme F. Prevention of venous thromboembolism after knee arthroplasty. A randomized, double-blind trial comparing enoxaparin with warfarin. Ann Intern Med 1996; 124: 619-26.
36. Francis CW, Pellegrini VD, Totterman S, Boyd AD, Marder VJ, Liebert KM, Stulberg BN, Ayers DC, Rosenberg A, Kessler C, Johanson NA. Prevention of deep-vein thrombosis after total hip arthroplasty. Comparison of warfarin and dalteparin. J Bone Joint Surg Am 1997; 79-A: 1365-72.
37. Heit JA, Berkowitz SD, Bona R, Cabanas V, Corson JD, Elliott CG, Lyons R (Ardeparin Arthroplasty Study Group). Efficacy and safety of low molecular weight heparin (ardeparin sodium) compared to warfarin for the prevention of venous thromboembolism after total knee replacement surgery: a double-blind, dose-ranging study. Thromb Haemost 1997; 77: 32-8.
38. Colwell CW, Collis DK, Paulson R, McCutchen JW, Bigler GT, Lutz S, Hardwick ME. Comparison of enoxaparin and warfarin for the prevention of venous thromboembolic disease after total hip arthroplasty. Evaluation during hospitalization and three months after discharge. J Bone Joint Surg Am 1999; 81-A: 932-40.
39. Hull RD, Pineo GF, Francis C, Bergqvist D, Fellenius C, Soderberg K, Holmqvist A, Mant M, Dear R, Baylis B, Mah A, Brant R for the North American Trial Investigators. Low-molecular-weight heparin prophylaxis using dalteparin in close proximity to surgery vs warfarin in hip arthroplasty patients. Arch Intern Med 2000; 160: 2199-207.
40. Fitzgerald RH, Spiro TE, Trowbridge AA, Gardiner Jr GA, Whitsett TL, O'Connell MB, Ohar JA, Young TR, for the Enoxaparin Clinical Trial Group. Prevention of venous thromboembolic disease following primary total knee arthroplasty. A randomized, multicenter, openlabel, parallel-group comparison of enoxaparin and warfarin. J Bone Joint Surg Am 2001; 83-A: 900-6.
41. Samama CM, Vray M, Barré J, Fiessinger JN, Rosencher N, Lecompte T, Potron G, Basile J, Hull R, Desmichels D for the SACRE study. Extended venous thromboembolism prophylaxis after total hip replacement. A comparison of low-molecular-weight heparin with oral anticoagulant. Arch Intern Med 2002; 162: 2191-6.
42. Gerhart TN, Yett HS, Robertson LK, Lee MA, Smith M, Salzman EW. Low-molecular-weight heparinoid compared with warfarin for prophylaxis of deep-vein thrombosis in patients who are operated on for fracture of the hip. J Bone Joint Surg Am 1991; 73-A: 494-502.
43. Comp PC, Voegeli T, McCutchen JW, Skoutakis VA, Trowbridge A, Overdyke WL for the Danaparoid Hip Arthroplasty Investigators Group. A comparison of danaparoid and warfarin for prophylaxis against deep vein thrombosis after total hip replacement. Orthopedics 1998; 21: 1123-8.
44. Mismetti P, Laporte-Simitsidis S, Tardy B, Queneau P, Decousus H. Prophylaxis of post operative venous thrombosis and pulmonary embolism by oral anticoagulants: a meta-analysis. Clin Trial Meta-Analysis 1993; 28: 227-40.
45. Collins R, Scrimgeour A, Yusuf S, Peto R. Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. Overview of results of randomized trials in general, orthopedic, and urologic surgery. N Engl J Med 1988; 318: 1162-73.
46. Leizorovicz A, Haugh MC, Chapuis F-R, Samama MM, Boissel J-P. Low molecular weight heparin in prevention of postoperative thrombosis. Br Med J 1992; 305: 913-20.
47. Nurmohamed MT, Rosendaal FR, Büller HR, Dekker E, Hommes DW, Vandenbroucke JP, Briet F. Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery. Lancet 1992; 340: 152-6.
48. Mismetti P, Laporte-Simitsidis S, Tardy B, Cucherat M, Buchmüller A, Juillard-Delsart D, Decousus H. Prevention of venous thromboembolism in internal medicine with unfractionated or low-molecular-weight heparins: a meta-analysis of randomised clinical trials. Thromb Haemost 2000; 83: 14-9.
49. Mismetti P, Laporte S, Darmon JY, Buchmüller A, Decousus H. Meta-analysis of low molecular weight heparin in the prevention of venous thromboembolism in general surgery. Br J Surg 2001; 88 913-30.
50. Havig Ö. Deep vein thrombosis and pulmonary embolism: an autopsy study with multiple regression analysis of possible risk factors. Acta Chir Scand 1977; 478 (Suppl.): 1-120.
51. Moser KM, LeMoine JR. Is embolic risk conditioned by location of deep venous thrombosis? Ann Intern Med 1981; 94: 439-44.
52. Eriksson BI, Kälebo P, Anthmyr BA, Wadenvik H, Tengborn L, Risberg B. Prevention of deep-vein thrombosis and pulmonary embolism after total hip replacement. comparison of low-molecular-weight heparin and unfractionated heparin. J Bone Joint Surg Am 1991; 73-A: 484-93.
53. Bhandari M, Morrow F, Kulkarni AV, Tornetta P. Meta-analyses in orthopaedic surgery. A systematic review of their methodologies. J Bone Joint Surg Am 2001; 83-A: 15-24.
54. Greenland S, Salvan A. Bias in the one-step method for pooling study results. Statist Med 1990; 9: 247-52.
55. Feller JA, Parkin JD, Phillips GW, Hannon PJ, Hennessy O, Huggins RM. Prophylaxis against venous thrombosis after total hip arthroplasty. Aust NZ J Surg 1992; 62: 606-10.
56. Fordyce MJF, Baker AS, Staddon GE. Efficacy of fixed minidose warfarin prophylaxis in total hip replacement. Br Med J 1991; 303: 219-20.
57. Dale C, Gallus A, Wycherley A, Langlois S, Howie D. Prevention of venous thrombosis with minidose warfarin after joint replacement. Br Med J 1991; 303: 224.
58. Poller L, Thomson JM, McCallum PK, Nicholson DA, Weighill FJ, Lemon JG. Minidose warfarin and failure to prevent deep vein thrombosis after joint placement surgery despite inhibiting the postoperative rise in plasminogen activator inhibitor activity. Clin Appl Thromb Hemost 1995; 1: 265-73.
59. Hull RD, Pineo GF, Stein PD, Mah AF, MacIsaac SM, Dahl OE, Ghali WA, Butcher MS, Brant RF, Bergqvist D, Hamulyak K, Francis CW, Marder VJ, Raskob GE. Timing of initial administration of low-molecular weight heparin prophylaxis against deep vein thrombosis in patients following elective hip arthroplasty. A systematic review. Ann Intern Med 2001; 161: 1952-60.
60. Swierstra BA, Stibbe J, Schouten HJA. Prevention of thrombosis after hip arthroplasty. A prospective study of preoperative oral anticoagulants. Acta Orthop Scand 1988; 59: 139-43.
61. Francis CW, Pellegrini VD, Leibert KM, Totterman S, Azodo MV, Harris CM, Cox C, Marder VJ. Comparison of two warfarin regimens in the prevention of venous thrombosis following knee replacement. Thromb Haemost 1996; 75: 706-1.