Corneal anomalies in murine trisomy 16;Minoranomalien der hornhaut bei der murinen trisomie 16

Ophthalmologe

Volumn 102, Issue 1, 2005, Pages 64-69

  Tost, F ^a   Wolfinger, J ^a   Giebel, J ^a   Buselmaier, W ^b  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Down's syndrome; Keratoconus; Minor anomalies of the cornea; Trisomy

Indexed keywords

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA DISEASE; CORNEA EPITHELIUM; DEVELOPMENTAL DISORDER; DOWN SYNDROME; EPITHELIUM CELL; EYE MALFORMATION; EYELID DISEASE; FETUS; KERATOCONUS; LENS DISEASE; MICROSCOPY; MOUSE; NONHUMAN; PARENCHYMA; PREGNANCY; TISSUE SECTION; TRANSGENE; TRISOMY 16;

EID: 13144257733     PISSN: 0941293X     EISSN: 14330423     Source Type: Journal    
DOI: 10.1007/s00347-004-1062-9     Document Type: Article

References (31)

1. Bacchus C, Sterz H, Buselmaier W (1987) Genesis and systematization of cardiovaskular anomalies and analysis of skeletal malformations in murine trisomy 16 and 19. Human Genet 77:12-22
2. Berger CN, Epstein CJ (1989) Delayed thymocyte maturation in the trisomy 16 mouses. J Immunol 143:389-396
3. Buselmaier W, Bacchus C, Sterz H (1991) Genesis and systematization of cardiovascular anomalies in murine trisomy 16. Prog Clin Biol Res 373:203-214
4. Colton CA, Yao J, Jaffs RE (1991) Abnormal production of interleukin-1 by microglia from trisomy 16 mice. Neurosci Lett 132:270-274
5. Cox D, Goldblatt D, Epstein CJ (1981) Chromosomal assignment of mouse PRGS: Further evidence for homology between mouse chromosome 16 and human chromosome 21. Am J Hum Genet 33:145
6. Epstein CJ, Epstein LB, Cox D (1998) Functional implications of gene dosage effects in trisomy 21. Hum Genet 2:155-172
7. Ewart JL, Auerbach R (1992) Defects in thymocyte differentiation and thymocyte-stromal interactions in the trisomy 16 mouse. Dev Immunol 2:215-226
8. Fundele R, Winking H, Jägerbauer EM (1987) Influence of mouse trisomy 16 on expression of specific genes. Dev Genetics 8:35-43
9. Gearhart JD, Davisson MT, Oster-Granite ML (1986) Autosomal aneuploidy in mice: generation and developmental consequences. Brain Res Bull 16:789-801
10. Grausz H, Richtsmeier JT, Oster-Granite ML (1991) Morphogenesis of the brain and craniofacial complex in trisomy 16 mice. Prog Clin Biol Res 373:169-188
11. Hiltgen GG, Markwald RR, Litke LL (1996) Morphogenetic alterations during endocardial cushon development in the trisomy 16 (Down syndrome) mouse. Pediatr Cardiol 17:21-30
12. Lacey-Casem ML, Oster-Granite ML (1994) The neuropathology of the trisomy 16 mouse. Crit Rev Neurobiol 8:293-322
13. Lane NL, Balbo A, Stoll J (1994) Long-term intracerebral transplants of fetal hippocampus from mouse trisomy 16, a model for Downs syndrome (Trisomy 21), do not exhibit Alzheimer disease neuropathology by ultrastructural criteria. Tissue Cell 26:477-488
14. Leffler A, Wedel T, Busch LC (1999) Congenital colonic hypoganglionosis in murine trisomy 16 - An animal model for Down's syndrome. Eur J Pediatr Surg 9:381-388
15. Lipski DA, Bersu ET (1990) Examination of the eyelid closure defect in trisomy 16 mice. Teratology 42:301-308
16. Miyabara S, Gropp A, Winking H (1982) Trisomy 16 in the mouse fetuses associated with generalized edema and cardiovasculae and urinary tract anomalies. Teratology 25:369-380
17. Miyabara S, Sugihara H, Yonemitsu N (1984) Comparative study of phenotypic expression of mico trisomy 16 by different female strains: attempt at an animal model for human trisomy 21. Congenital Anom 24:283-292
18. Müller W, Heinemann U, Schuchmann S (1997) Impaired Ca-signaling in astrocyts from the Ts 16 mouse model of Down syndrome. Neurosci Lett 223:81-84
19. Naumann GOH (1997) Pathologie des Auges. Springer, Berlin Heidelberg New York Tokyo, S 133-134
20. Nelson PG, Fitzgerald S, Rapoport SI (1997) Cerebral cortical astroglia from the trisomy 16 mouse, a model for Down syndrome, produce neuronal cholinergic deficits in cell culture. Proc Natl Aca Sci USA 94:12644-12648
21. Oster-Granite ML, Baker C, Ozand PT (1983) Neuroanatomic, ocular and audiovestibular malformations in the trisomy 16 mouse. Pediatr Res 17:300
22. Oster-Granite ML, Gerhart JD, Reeves RH (1986) Neurobiological consequences of trisomy 16 in mice. In: Epstein CJ (ed) The neurobiology of Down syndrome. Raven, New York, pp 137-151
23. Pei YF, Thodin JA (1971) Electron microscopic study of the development of the mouse corneal epithelium. Invest Ophthalmol 10:811-825
24. Saltarelli MD, Forloni GL, Oster-Granite ML (1987) Neurochemical characterization of embryonic brain development in trisomy 19 (Ts 19) mice: implications of selective deficits observed for abnormal neuron development in aneuploidy. Dev Genet 8:267-279
25. Schuchmann S, Heinemann U (2000) Diminished glutathione levels cause spontaneous and mitochondria-mediated cell death in neurons from trisomy 16 mice: A model of Down's syndrome. J Neurochem 74:1205-1214
26. Schuchmann S, Müller W, Heidemann U (1998) Alterated Ca signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndroma. J Neurosci 18:7216-7231
27. Shapiro MB, France TD (1985) The ocular features of Down's syndrome. Am J Ophthalmol 99:659-663
28. Shetty HU, Holloway HW, Rapoport SI (1995) Capillary gas chromatography combined with ion trap detection for quantitative profiling of polyols in cerebrospinal fluid and plasma. Anal Biochem 224:279-285
29. Sterz H, Buselmaier W, Bacchus C (1989) Defects of skeletal morphology, density, and structure in mouse fetuses with trisomy 16. Teratology 40:627-639
30. Tost M, Tost F (1990) Zur Normogenese der Hornhaut und ihrer Beeinflussung durch Cyclophosphamid. Klin Monatsbl Augenheilkd 197:123-127
31. Webb S, Brown NA, Anderson RH (1997) Cardiac morphology at late fetal stages in the mouse with trisomy 16: consequences for different formation of the atrioventricular junction when compared to humans with trisomy 21. Cardiovasc Res 34:515-525