Nestin-positive mesenchymal stem cells favour the astroglial lineage in neural progenitors and stem cells by releasing active BMP4

BMC Neuroscience

Volumn 5, Issue , 2004, Pages

  Wislet Gendebien, Sabine ^a   Bruyère, Françoise ^a   Hans, Grégory ^a,b   Leprince, Pierre ^a   Moonen, Gustave ^a,b   Rogister, Bernard ^a,b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; CELL PROTEIN; CILIARY NEUROTROPHIC FACTOR; CYTOKINE; MESSENGER RNA; MONOCLONAL ANTIBODY; NESTIN; BMP4 PROTEIN, MOUSE; BMP4 PROTEIN, RAT; BONE MORPHOGENETIC PROTEIN; DIFFERENTIATION ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERMEDIATE FILAMENT PROTEIN; NERVE PROTEIN;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CELL COUNT; CELL FATE; CELL LINEAGE; CELL POPULATION; CELL STIMULATION; CONTROLLED STUDY; CORPUS STRIATUM; CULTURE MEDIUM; EMBRYO; ENZYME INHIBITION; ENZYME RELEASE; MESENCHYMAL STEM CELL; MOUSE; NERVE CELL CULTURE; NEURAL STEM CELL; NONHUMAN; OLIGODENDROGLIA; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; BIOSYNTHESIS; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL DIVISION; COCULTURE; CYTOLOGY; DRUG EFFECT; GENETICS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; METABOLISM; METHODOLOGY; MOUSE STRAIN; NERVE CELL; PHYSIOLOGY; SECRETION (PROCESS); STEM CELL;

ANIMALS; ANTIGENS, DIFFERENTIATION; ASTROCYTES; BONE MARROW CELLS; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEINS; CELL COUNT; CELL DIFFERENTIATION; CELL DIVISION; CELL LINEAGE; CELLS, CULTURED; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; CYTOKINES; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERMEDIATE FILAMENT PROTEINS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED STRAINS; NERVE TISSUE PROTEINS; NEURONS; RATS; RNA, MESSENGER; STEM CELLS;

EID: 12944284421     PISSN: 14712202     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2202-5-33     Document Type: Article

References (57)

1. Gage FH: Mammalian neural stem cells. Science 2000, 287:1433-1438.
2. McKay R: Stem cells in the central nervous system. Science 1997, 276:66-71.
3. Alvarez-Buylla A, Temple S: Stem cells in the developing and adult nervous system. J Neurobiol 1998, 36:105-110.
4. van der Kooy D, Weiss S: Why stem cells? Science 2000, 287:1439-1441.
5. Edlund T, Jessell TM: Progression from extrinsic to intrinsic signaling in cell fate specification: a view from the nervous system. Cell 1999, 96:211-224.
6. Song H, Stevens CH, Gage FH: Astroglia induce neurogenesis from adult neural stem cells. Nature 2002, 417(6884): 9-44.
7. Furuta Y, Piston DW, Hogan BL: Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development. Development 1997, 124:2203-2212.
8. Mehler MF, Mabie PC, Zhang D, Kessler JA: Bone morphogenetic proteins in the nervous system. Trends Neurosci 1997, 20:309-317.
9. Zhang D, Mehler MF, Song Q, Kessler JA: Development of bone morphogenetic protein receptors in the nervous system and possible roles in regulating trkC expression. J Neurosci 1998, 18: 314-3326.
10. Liem KF Jr, Tremml G, Roelink H, Jessell TM: Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell 1995, 82:969-979.
11. Schluesener HJ, Meyermann R: Expression of BMP-6, a TGF-beta related morphogenetic cytokine, in rat radial glial cells. Glia 1994, 12:161-164.
12. Bhatia M, Bonnet D, Wu D, Murdoch B, Wrana J, Gallacher L, Dick JE: Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells. J Exp Med 1999, 189:1139-1148.
13. Naski MC, Colvin JS, Coffin JD, Ornitz DM: Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3. Development 1998, 125: 977-4988.
14. Nakayama N, Han CE, Scully S, Nishinakamura R, He C, Zeni L, Yamane H, Chang D, Yu D, Yokota T: A novel chordin-like protein inhibitor for bone morphogenetic proteins expressed preferentially in mesenchymal cell lineages. Dev Biol 2001, 232:372-387.
15. Miyazono K, Kusanagi K, Inoue H: Divergence and convergence of TGF-beta/BMP signaling. J Cell Physiol 2001, 187:265-276.
16. Winnier G, Blessing M, Labosky PA, Hogan BL: Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev 1995, 9:2105-2116.
17. Fann MJ, Patterson PH: Depolarization differentially regulates the effects of bone morphogenetic protein (BMP)-2, BMP-6, and activin A on sympathetic neuronal phenotype. [J Neurochem] 1994, 63:2074-2079.
18. Mujtaba T, Mayer-Proschel M, Rao MS: A common neural progenitor for the CNS and PNS. Dev Biol 1998, 200:1-15.
19. Sasai Y, Lu B, Steinbeisser H, De Robertis EM: Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 1995, 377:757.
20. Wilson PA, Hemmati-Brivanlou A: Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 1995, 376: 31-333.
21. Kalyani AJ, Piper D, Mujtaba T, Lucero MT, Rao MS: Spinal cord neuronal precursors generate multiple neuronal phenotypes in culture. J Neurosci 1998, 18:7856-7868.
22. Li W, Cogswell CA, LoTurco JJ: Neuronal differentiation of precursors in the neocortical ventricular zone is triggered by BMP. J Neurosci 1998, 18:8853-8862.
23. Mabie PC, Mehler MF, Kessler JA: Multiple roles of bone morphogenetic protein signaling in the regulation of cortical cell number and phenotype. J Neurosci 1999, 19:7077-7088.
24. Gross RE, Mehler MF, Mabie PC, Zang Z, Santschi L, Kessler JA: Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells. Neuron 1996, 17:595-606.
25. Isacson O, van Horne C, Schumacher JM, Brownell AL: Improved surgical cell therapy in Parkinson's disease: Physiological basis and new transplantation methodology. Adv Neurol 2001, 86:447-454.
26. Dunnett SB: Functional analysis of fronto-striatal reconstruction by striatal grafts. Novartis Found Symp 2000, 231:21-41.
27. Hall ED: Pharmacological treatment of acute spinal cord injury: how do we build on past success? J Spinal Cord Med 2001, 24:142-146.
28. Herzog EL, Chai L, Krause DS: Plasticity of marrow-derived stem cells. Blood 2003, 102:3483-3493.
29. Wagers AJ, Weissman IL: Plasticity adult stem cells. Cell 2004, 116:639-648.
30. Alvarez-Dolado M, Pardal R, Garcia-Verdugo JM, Fike JR, Lee HO, Pfeffer K, Lois C, Morrison SJ, Alvarez-Buylla A: Fusion of bonemarrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 2003, 425:968-973.
31. Weimann JM, Johansson CB, Trejo A, Blau HM: Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after bone marrow transplant. Nat Cell Biol 2003, 5:959-966.
32. Wislet-Gendebien S, Leprince P, Moonen G, Rogister B: Regulation of neural markers nestin and GFAP expression by cultivated bone marrow stromal cells. J Cell Sci 2003, 116:3295-3302.
33. Chen J, Li Y, Wang L, Zhang Z, Lu D, Lu M, Chopp M: Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke 2001, 32: 005-1011.
34. Harvey RL, Chopp M: The therapeutic effects of cellular therapy for functional recovery after brain injury. Phys Med Rehabil Clin N Am 2003, 14:S143-S151.
35. Teramoto T, Qiu J, Plumier JC, Moskovitz MA: EGF amplifies the replacement of parvalbumin-expressing striatal interneurons after ischemia. J Clin Invest 2003, 111:1125-32.
36. Gomes WA, Mehler MF, Kessler JA: Transgenic overexpression of BMP4 increases astroglial and decreases oligodendroglial lineage commitment. Dev Biol 2003, 255:164-177.
37. Yanagisawa M, Nakashima K, Takeda K, Ochiai W, Takizawa T, Ueno M, Takizawa M, Shibuya H, Taga T: Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7. Genes Cells 2001, 6:1091-109.
38. Gendall AR, Dunn AR, Ernst M: Isolation and characterization of a leukemia inhibitory factor-independent embryonic stem cell line. Int J Biochem Cell Biol 1997, 29:829-840.
39. Koblar SA, Turnley AM, Classon BJ, Reid KL, Ware CB, Cheema SS, Murphy M, Bartlett PF: Neural precursor differentiation into astrocytes requires signaling through the leukemia inhibitory factor receptor. Proc Natl Acad Sci U S A1998, 95:3178-3181.
40. Turnley AM, Bartlett PF: Cytokines that signal through the leukemia inhibitory factor receptor-beta complex in the nervous system. J Neurochem 2000, 74:889-899.
41. Rajan P, Panchision DM, Newell LF, McKay RD: BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells. J Cell Biol 2003, 161:911-921.
42. Kopen GC, Prockop DJ, Phinney DG: Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Natl Acad Sci U S A 1999, 96:10711-10716.
43. Lee J, Kuroda S, Shichinohe H, Ikeda J, Seki T, Hida K, Tada M, Sawada K, Iwasaki Y: Migration and differentiation of nuclear fluorescence-labeled bone marrow stromal cells after transplantation into cerebral infarct and spinal cord injury in mice. Neuropathology 2003, 23:169-180.
44. Nakano K, Migita M, Mochizuki H, Shimada T: Differentiation of transplanted bone marrow cells in the adult mouse brain. Transplantation 2001, 71:1735-1740.
45. Brazelton TR, Rossi FM, Keshet GI, Blau HM: From marrow to brain: expression of neuronal phenotypes in adult mice. Science 2000, 290:1775-1779.
46. Cuevas P, Carceller F, Dujovny M, Garcia-Gomez I, Cuevas B, Gonzalez-Corrochano R, Diaz-Gonzalez D, Reimers D: Peripheral nerve regeneration by bone marrow stromal cells. Neurol Res 2002, 24:634-638.
47. Wu S, Suzuki Y, Ejiri Y, Noda T, Bai H, Kitada M, Kataoka K, Ohta M, Chou H, Ide C: Bone marrow stromal cells enhance differentiation of cocultured neurosphere cells and promote regeneration of injured spinal cord. J Neurosci Res 2003, 72:343-351.
48. Cui Y, Jean F, Thomas G, Christian JL: BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development. EMBO J 1998, 17:4735-4743.
49. Constam DB, Robertson EJ: Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases. J Cell Biol 1999, 144:139-149.
50. Yoshida I, Koide S, Hasegawa SI, Nakagawara A, Tsuji A, Matsuda Y: Proprotein convertase PACE4 is down-regulated by the basic helix-loop-helix transcription factor hASH-1 and MASH-1. Biochem J 2001, 360:683-689.
51. Grinspan JB, Edell E, Carpio DF, Beesley JS, Lavy L, Pleasure D, Golden JA: Stage-specific effects of bone morphogenetic proteins on the oligodendrocyte lineage. J Neurobiol 2000, 43:1-17.
52. Mehler MF, Mabie PC, Zhu G, Gokhan S, Kessler JA: Developmental changes in progenitor cell responsiveness to bone morphogenetic proteins differentially modulate progressive CNS lineage fate. Dev Neurosci 2000, 22:74-85.
53. Iantosca MR, McPherson CE, Ho SY, Maxwell GD: Bone morphogenetic proteins-2 and -4 attenuate apoptosis in a cerebellar primitive neuroectodermal tumor cell line. J Neurosci Res 1999, 56:248-258.
54. Agius E, Soukkarieh C, Danesin C, Kan P, Takebayashi H, Soula C, Cochard P: Converse control of oligodendrocyte and astrocyte lineage development by Sonic hedgehog in the chick spinal cord. Dev Biol 2003, 270:308-321.
55. Mekki-Dauriac S, Agius E, Kan P, Cochard P: Bone morphogenetic proteins negatively control oligodendrocyte precursor specification in the chick spinal cord. Development 2002, 129:5117-5130.
56. Azizi SA, Stokes D, Augelli BJ, DiGirolamo C, Prockop DJ: Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats - similarities to astrocyte grafts. Proc Natl Acad Sci U S A 1998, 95:3908-3913.
57. Okabe M, Ikawa M, Kominami K, Nakanishi T, Nishimune Y: 'Green mice' as a source of ubiquitous green cells. FEBS Lett 1997, 407:313-319.