Leptomycin B reduces matrix metalloproteinase-9 expression and suppresses cutaneous inflammation

Journal of Investigative Dermatology

Volumn 124, Issue 2, 2005, Pages 331-337

  Kobayashi, Takashi ^a   Shinkai, Hiroshi ^a  

^a CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Fibroblast; Keratinocyte; Skin; Ultraviolet B

Indexed keywords

CALCIUM ION; GELATINASE A; GELATINASE B; INTERLEUKIN 1ALPHA; LEPTOMYCIN B; PHORBOL 13 ACETATE 12 MYRISTATE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; KERATINOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATOR GENE; REGULATORY MECHANISM; SKIN INFLAMMATION; ULTRAVIOLET B RADIATION;

EID: 12944265409     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2004.23595.x     Document Type: Article

References (42)

1. Benassi L, Ottani D, Fantini F, Marconi A, Hiodino C, Ginaetti A, Pincelli C: 1, 25-dihydroxyvitamin D3, transforming growth factor β1, calcium, and ultraviolet B radiation induce apoptosis in cultured human keratinocytes. J Invest Dermatol 109:276-282, 1997
2. Bergers G, Brekken R, McMahon G, et al: Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol 2:737-744, 2002
3. Coussens LM, Tinkle CL, Hanahan D, Werb Z: MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 103:481-490, 2000
4. Fisher GJ, Datta SC, Talwar HS, Wang ZQ, Varani J, Kang S, Voorhees JJ: Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature 379:335-339, 1996
5. Fisher GJ, Wang ZQ, Datta SC, Varani J, Kang S, Voorhees JJ: Pathophysiology of premature skin aging induced by ultraviolet light. N Engl J Med 337:1419-1428, 1997
6. Fornerod M, van Deursen J, van Baal S, et al: The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88. EMBO J 16:807-816, 1997a
7. Fornerod M, Ohno M, Yoshida M, Mattaj IW: CRM1 is an export receptor for leucine-rich nuclear export signals. Cell 90:1051-1060, 1997b
8. Greber UF, Carafoli E: Signalling takes control of nucleo-cytoplasmic trafficking. Workshop on signal-regulated nuclear transport. EMBO Rep 3:410-414, 2002
9. Gum R, Wang H, Lengyel E, Juarez J, Boyd D: Regulation of 92 kDa type IV collagenase expression by the jun amino terminal kinase- and the extracellular signal-regulated kinase-dependent signaling cascades. Oncogene 14:1481-1493, 1997
10. Hamamoto T, Gunji S, Tsuji H, Beppu T: Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization. J Antibiot (Tokyo) 36:639-645, 1983a
11. Hamamoto T, Seto H, Beppu T: Leptomycins A and B, new antifungal antibiotics. II. Structure elucidation. J Antibiot (Tokyo) 36:646-650, 1983b
12. Han YP, Tuan TL, Hughes M, Wu H, Garner WL: Transforming growth factor-β-and tumor necrosis factor-α-mediated induction and proteolytic activation of MMP-9 in human skin. J Biol Chem 276:22341-22350, 2001
13. Himelstein BP, Lee EJ, Sato H, Seiki M, Muschel RJ: Transcriptional activation of the matrix metalloproteinase-9 gene in an H-ras and v-myc transformed rat embryo cell line. Oncogene 14:1995-1998, 1997
14. Kleiner DE, Stetler-Stevenson WG: Structural biochemistry and activation of matrix metalloproteinases. Curr Opin Cell Biol 5:891-897, 1993
15. Kleiner DE, Stetler-Stevenson WG: Quantitative zymography: Detection of picogram quantities of gelatinases. Anal Biochem 218:325-329, 1994
16. Kobayashi T: MMP-9 and TIMP-1 assays in keratinocyte cultures. In: Turksen K (ed). Methods in Molecular Biology, Vol. 289: Epidermal Cells, Methods and Applications. Totowa: Humana Press, 2004; p 201-208
17. Kobayashi T, Hattori S, Shinkai H: Matrix metalloproteinases-2 and -9 are secreted from human fibroblasts. Acta Derm Venereol 83:105-107, 2003
18. Kobayashi T, Kishimoto J, Ge Y, et al: A novel mechanism of matrix metalloproteinase-9 gene expression implies a role for keratinization. EMBO Rep 2:604-608, 2001
19. Kobayashi T, Kishimoto J, Hattori S, Wachi H, Shinkai H, Burgeson RE: Matrix metalloproteinase 9 expression is coordinately modulated by the KRE-M9 and 12-o-tetradecanoyl-phorbol-13-acetate responsive elements. J Invest Dermatol 122:278-285, 2004
20. Kobayashi T, Onoda N, Takagi T, et al: Immunolocalizations of human gelatinase (type IV collagenase, MMP-9) and TIMP (tissue inhibitor of metalloproteinases) in normal epidermis and some epidermal tumors. Arch Dermatol Res 288:239-244, 1996
21. Komiyama K, Okada K, Tomisaka S, Umezawa I, Hamamoto T, Beppu T: Anti-tumor activity of leptomycin B. J Antibiot (Tokyo) 38:427-429, 1985
22. LaCelle PT, Polakowska RR: Human homeobox HOXA7 regulates keratinocyte transgiutaminase type 1 and inhibits differentiation. J Biol Chem 276:32844-32853, 2001
23. Liu Z, Shipley JM, Vu TH, Zhou X, Diaz LA, Werb Z, Senior RM: Gelatinase B-deficient mice are resistant to experimental bullous pemphigoid. J Exp Med 188:475-482, 1998
24. McCawley LJ, Matrisian LM: Matrix metalloproteinases: They're not just for matrix anymore! Curr Opin Cell Biol 13:534-540, 2001
25. Muegge K, Vila M, Gusella GL, Musso T, Herrlich P, Stein B, Durum SK: Interleukin 1 induction of the c-jun promoter. Proc Natl Acad Sci USA 90:7054-7058, 1993
26. Newlands ES, Rustin GJ, Brampton MH: Phase I trial of elactocin. Br J Cancer 74:648-649, 1996
27. Nishi K, Yoshida M, Fujiwara D, Nishikawa M, Horinouchi S, Beppu T: Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression. J Biol Chem 269:6320-6324, 1994
28. Okada Y, Watanabe S, Nakanishi I, et al: Inactivation of tissue inhibitor of metalloproteinases by neutrophil elastase and other serine proteinases. FEBS Lett 229:157-160, 1988
29. Onoue S, Kobayashi T, Takemoto Y, Sasaki I, Shinkai H: Induction of matrix metalloproteinase-9 secretion from human keratinocytes in culture by ultraviolet B irradiation. J Dermatol Sci 33:105-111, 2003
30. Salo T, Lyons JG, Rahemtulla F, Birkedal-Hansen H, Larjava H: Transforming growth factor-β1 up-regulates type IV collagenase expression in cultured human keratinocytes. J Biol Chem 266:11436-11441, 1991
31. Sato H, Kita M, Seiki M: v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines. J Biol Chem 268:23460-23468, 1993
32. Sato H, Seiki M: Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene 8:395-405, 1993
33. Segain JP, Harb J, Gregoire M, Meflah K, Menanteau J: Induction of fibroblast gelatinase B expression by direct contact with cell lines derived from primary tumor but not from metastases. Cancer Res 56:5506-5512, 1996
34. Ståhle-Bäckdahl M, Inoue M, Guidice GJ, Parks WC: 92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of recombinant 180-kD bullous pemphigoid autoantigen. J Clin Invest 93:2022-2030, 1994
35. Ullman KS, Powers MA, Forbes DJ: Nuclear export receptors: From importin to exportin. Cell 90:967-970, 1997
36. Vayalil PK, Mittal A, Hara Y, Elmets CA, Katiyar SK: Green tea polyphenols prevent ultraviolet light-induced oxidative damage and matrix metalloproteinases expression in mouse skin. J Invest Dermatol 122:1480-1487, 2004
37. Verraes S, Hornebeck W, Polette M, Borradori L, Bernard P: Respective contribution of neutrophil elastase and matrix metalloproteinase 9 in the degradation of BP180 (type XVII collagen) in human bullous pemphigoid. J Invest Dermatol 117:1091-1096, 2001
38. Verrecchia F, Wagner EF, Mauviel A: Distinct involvement of the Jun-N-terminal kinase and NF-κB pathways in the repression of the human COL1A2 gene by TNF-α. EMBO Rep 3:1069-1074, 2002
39. Wilhelm SM, Collier IE, Marmer BL, Eisen AZ, Grant GA, Goldberg GI: SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages. J Biol Chem 264:17213-17221, 1989
40. Wong H, Muzik H, Groft LL, et al: Monitoring MMP and TIMP mRNA expression by RT-PCR. In: Clark IM (ed). Methods in Molecular Biology, Vol. 151: Matrix Metalloproteinase Protocols. Totowa: Humana Press, 2001; p 305-320
41. Yokoo T, Kitamura M: Dual regulation of IL-1 beta-mediated matrix metalloproteinase-9 expression in mesangial cells by NF-kappa B and AP-1. Am J Physiol 270:F123-F130, 1996
42. Yoshida M, Nishikawa M, Nishi K, Abe K, Horinouchi S, Beppu T: Effects of leptomycin B on the cell cycle of fibroblasts and fission yeast cells. Exp Cell Res 187:150-156, 1990