Different endocytosis pathways of the C5a receptor and the N-formyl peptide receptor

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Volumn 6, Issue 2, 2005, Pages 100-115

  Suvorova, Elena S ^a   Gripentrog, Jeannie M ^a   Miettinen, Heini M ^a  

^a MONTANA STATE UNIVERSITY   (United States)

Author keywords

C5aR; Chemotaxis; Endocytosis; FPR; GPCR; Neutrophils; Receptor targeting

Indexed keywords

COMPLEMENT COMPONENT C5A RECEPTOR; FORMYLPEPTIDE RECEPTOR; GLYCEROL; RAB PROTEIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL SURFACE; CELLULAR DISTRIBUTION; CHEMOTAXIS; CHO CELL; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; ENDOSOME; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; LYSOSOME; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CHEMOTAXIS; CHO CELLS; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENDOCYTOSIS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GREEN FLUORESCENT PROTEINS; LIGANDS; MICROSCOPY, CONFOCAL; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; RECEPTOR, ANAPHYLATOXIN C5A; RECEPTORS, FORMYL PEPTIDE;

EID: 12744261611     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2004.00256.x     Document Type: Article

References (52)

1. 2-adrenergic receptor. Nature 1996;383: 447-450.
2. 2-adrenergic receptor into clathrin-coated pits. J Biol Chem 2000; 275:23120-23126.
3. Kohout TA, Lefkowitz RJ. Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization. Mol Pharmacol 2003;63:9-18.
4. von Zastrow M. Mechanisms regulating membrane trafficking of G protein-coupled receptors in the endocytic pathway. Life Sci 2003;74:217-224.
5. Robinson MS, Watts C, Zerial M. Membrane dynamics in endocytosis. Cell 1996;84:13-21.
6. Innamorati G, Le Gouill C, Balamotis M, Birnbaumer M. The long and the short cycle. Alternative intracellular routes for trafficking of G-protein-coupled receptors. J Biol Chem 2001;276:13096-13103.
7. Gilbert TL, Bennett TA, Maestas DC, Cimino DF, Prossnitz ER. Internalization of the human N-formyl peptide and C5a chemoattractant receptors occurs via clathrin-independent mechanisms. Biochemistry 2001;40:3467-3475.
8. Vines CM, Revankar CM, Maestas DC, LaRusch LL, Cimino DF, Kohout TA, Lefkowitz RJ, Prossnitz ER. N-formyl peptide receptors internalize but do not recycle in the absence of arrestins. J Biol Chem 2003;278:41581-41584.
9. Braun L, Christophe T, Boulay F. Phosphorylation of key serine residues is required for internalization of the complement 5a (C5a):anaphylatoxin receptor via a β-arrestin, dynamin, and clathrin-dependent pathway. J Biol Chem 2003;278:4277-4285.
10. Bennett TA, Maestas DC, Prossnitz ER. Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated by the conserved 'DRY' sequence. J Biol Chem 2000;275:24590-24594.
11. Giannini E, Boulay F. Phosphorylation, dephosphorylation, and recycling of the C5a receptor in differentiated HL60 cells. J Immunol 1995;154:4055-4064.
12. Naik N, Giannini E, Brouchon L, Boulay F. Internalization and recycling of the C5a anaphylatoxin receptor. evidence that the agonist-mediated internalization is modulated by phosphorylation of the C-terminal domain. J Cell Sci 1997;110:2381-2390.
13. Zigmond SH, Sullivan SJ, Lauffenburger DA. Kinetic analysis of chemotactic peptide receptor modulation. J Cell Biol 1982;92:34-43.
14. van Epps DE, Simpson S, Bender JG, Chenoweth DE. Regulation of C5a and formyl peptide receptor expression on human polymorphonuclear leukocytes. J Immunol 1990;144:1062-1068.
15. Miettinen HM, Gripentrog JM, Jesaitis AJ. Chemotaxis of Chinese hamster ovary cells expressing the human neutrophil formyl peptide receptor: role of signal transduction molecules and α 5β1 integrin. J Cell Sci 1998;111:1921-1928.
16. Gripentrog JM, Jesaitis AJ, Miettinen HM. A single amino acid substitution (N297A) in the conserved NPXXY sequence of the human N-formyl peptide receptor results in inhibition of desensitization and endocytosis, and a dose-dependent shift in p42/44 mitogen-activated protein kinase activation and chemotaxis. Biochem J 2000; 352:399-407.
17. Miettinen HM, Gripentrog JM, Mason MM, Jesaitis AJ. Identification of putative sites of interaction between the human formyl peptide receptor and G protein. J Biol Chem 1999;274:27934-27942.
18. Law PY, Hom DS, Loh HH. Down-regulation of opiate receptor in neuroblastoma × glioma NG108-15 hybrid cells. Chloroquine promotes accumulation of tritiated enkephalin in the lysosomes. J Biol Chem 1984;259:4096-4104.
19. Ko JL, Arvidsson U, Williams FG, Law PY, Elde R, Loh HH. Visualization of time-dependent redistribution of δ-opioid receptors in neuronal cells during prolonged agonist exposure. Brain Res Mol Brain Res 1999;69: 171-185.
20. Maxfield FR. Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts. J Cell Biol 1982;95:676-681.
21. 2-adrenergic receptor dephosphorylation by vesicular acidification. J Biol Chem 1997;272:5-8.
22. Tardif M, Mery L, Brouchon L, Boulay F. Agonist-dependent phosphorylation of N-formylpeptide and activation peptide from the fifth component of C (C5a) chemoattractant receptors in differentiated HL60 cells. J Immunol 1993;150:3534-3545.
23. Lim SN, Bonzelius F, Low SH, Wille H, Weimbs T, Herman GA. Identification of discrete classes of endosome-derived small vesicles as a major cellular pool for recycling membrane proteins. Mol Biol Cell 2001;12:981-995.
24. Gruenberg J, Maxfield FR. Membrane transport in the endocytic pathway. Curr Opin Cell Biol 1995;7:552-563.
25. Luttrell LM, Lefkowitz RJ. The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals. J Cell Sci 2002; 115:455-465.
26. Oakley RH, Laporte SA, Holt JA, Caron MG, Barak LS. Differential affinities of visual arrestin, β arrestin1, and β arrestin2 for G protein-coupled receptors delineate two major classes of receptors. J Biol Chem 2000;275:17201-17210.
27. Van Epps DE, Chenoweth DE. Analysis of the binding of fluorescent C5a and C3a to human peripheral blood leukocytes. J Immunol 1984;132:2862-2867.
28. Van Epps DE, Simpson SJ, Johnson R. Relationship of C5a receptor modulation to the functional responsiveness of human polymorphonuclear leukocytes to C5a. J Immunol 1993;150:246-252.
29. Guo R-F, Riedemann NC, Ward PA. Role of C5a-C5aR interaction in sepsis. Shock 2004;21:1-7.
30. Snyderman R, Uhing RJ. Chemoattractant stimulus - response coupling. In: Gallin, JI, Goldstein, IM, Snyderman, R, eds. Inflammation: Basic Principles and Clinical Correlates, 2nd edn. New York: Raven Press, 1992: 421-439.
31. Guo R-F, Riedemann NC, Bernacki KD, Sarma VJ, Laudes IJ, Reuben JS, Younkin EM, Neff TA, Paulauskis JD, Zetoune FS, Ward PA. Neutrophil C5a receptor and the outcome in a rat model of sepsis. FASEB J 2003;17:1889-1891.
32. 2-adrenergic receptor. J Biol Chem 1998; 273: 322-328.
33. Tsao PI, von Zastrow MJ. Type-specific sorting of G protein-coupled receptors after endocytosis. Biol Chem 2000;275:11130-11140.
34. Trejo J, Altschuler Y, Fu HW, Mostov KE, Coughlin SR. Protease-activated receptor-1 down-regulation: a mutant HeLa cell line suggests novel requirements for PAR1 phosphorylation and recruitment to clathrin-coated pits. J Biol Chem 2000;275:31255-31265.
35. Oksche A, Boese G, Horstmeyer A, Furkert J, Beyermann M, Bienert M, Rosenthal W. Late endosomal/lysosomal targeting and lack of recycling of the ligand-occupied endothelin B receptor. Mol Pharmacol 2000;57:1104-1113.
36. Blaukat A, Micke P, Kalatskaya I, Faussner A, Muller-Esterl W. Down-regulation of bradykinin B2 receptor in human fibroblasts during prolonged agonist exposure. Am J Physiol Heart Circ Physiol 2003;284:H1909-H1916.
37. Urade R, Hayashi Y, Kito M. Endosomes differ from plasma membranes in the phospholipid molecular species composition. Biochim Biophys Acta 1988;946:151-163.
38. Jesaitis AJ, Naemura JR, Painter RG, Sklar LA, Cochrane CG. The fate of an N-formylated chemotactic peptide in stimulated human granulocytes. Subcellular fractionation studies. J Biol Chem 1983;258: 1968-1977.
39. Sengelov H, Voldstedlund M, Vinten J, Borregaard N. Human neutrophils are devoid of the integral membrane protein caveolin. J Leukoc Biol 1998;63:563-566.
40. Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG. Association of β-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. J Biol Chem 1999;274:32248-32257.
41. Whistler JL, Gerber BO, Meng EC, Baranski TJ, von Zastrow M, Bourne HR. Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor. Traffic 2002;3:866-877.
42. Bonifacino JS, Traub LM. Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu Rev Biochem 2003;72:395-447.
43. 2 adrenergic receptor to N-ethylmaleimide-sensitive factor regulates receptor recycling. J Biol Chem 2001;276: 45145-45152.
44. Whistler JL, Enquist J, Marley A, Fong J, Gladher F, Tsuruda P, Murray SR, Von Zastrow M. Modulation of postendocytic sorting of G protein-coupled receptors. Science 2002;297:615-620.
45. Wang Y, Zhou Y, Szabo K, Haft CR, Trejo J. Down-regulation of protease-activated receptor-1 is regulated by sorting nexin 1. Mol Biol Cell 2002;13:1965-1976.
46. Uthayakumar S, Granger BL. Cell surface accumulation of over-expressed hamster lysosomal membrane glycoproteins. Cell Mol Biol Res 1995;41:405-420.
47. Gripentrog JM, Kantele KP, Jesaitis AJ, Miettinen HM. Experimental evidence for lack of homodimerization of the G protein-coupled human N-formyl peptide receptor. J Immunol 2003;171:3187-3193.
48. Miettinen HM, Mills JS, Gripentrog JM, Dratz EA, Granger BL, Jesaitis AJ. The ligand binding site of the formyl peptide receptor maps in the transmembrane region. J Immunol 1997;159:4045-4054.
49. Parkos CA, Delp C, Arnaout MA, Madara JL. Neutrophil migration across a cultured intestinal epithelium. Dependence on a CD11b/CD18-mediated event and enhanced efficiency in physiological direction. J Clin Invest 1991;88:1605-1612.
50. Hwang J-I, Fraser IDC, Choi S, Qin X-F, Simon MI. Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA. Proc Natl Acad Sci U S A 2004;101:488-493.
51. Allen CA, Broom MF, Chadwick VS. Flow cytometry analysis of the expression of neutrophil FMLP receptors. J Immunol Methods 1992;149:159-164.
52. Sklar LA, Finney DA, Oades ZG, Jesaitis AJ, Painter RG, Cochrane CG. The dynamics of ligand-receptor interactions. Real-time analyses of association, dissociation, and internalization of an N-formyl peptide and its receptors on the human neutrophil. J Biol Chem 1984;259: 5661-5669.