Maternal mutation 677C>T in the methylenetetrathydrofolate reductase gene associated with severe brain injury in offspring

Clinical Genetics

Volumn 67, Issue 1, 2005, Pages 69-80

  de Kremer, R Dodelson ^a   Grosso, C ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

5,10 methylenetetrahydrofolate reductase; 677C>T; Acute brain injury; Homocysteine toxicity; Magnetic resonance imaging; Maternal metabolic defect; Multicystic encephalomalacia

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); FOLIC ACID; HOMOCYSTEINE; METHIONINE;

ADULT; ARTICLE; BRAIN DISEASE; BRAIN HYPOXIA; BRAIN ISCHEMIA; CEREBROVASCULAR DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENCEPHALOMALACIA; FEMALE; FOLIC ACID DEFICIENCY; GENE FREQUENCY; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HYPERHOMOCYSTEINEMIA; INFANT; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; NUTRITIONAL STATUS; PREVALENCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK FACTOR;

BRAIN DAMAGE, CHRONIC; CASE-CONTROL STUDIES; CHILD; FAMILY HEALTH; FEMALE; GENOTYPE; HOMOCYSTEINE; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; INHERITANCE PATTERNS; MAGNETIC RESONANCE IMAGING; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MOTHERS; PEDIGREE; POINT MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 12744260249     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0004.2004.00373.x     Document Type: Article

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