Human seminal plasma displays significant phospholipid transfer activity due to presence of active phospholipid transfer protein

Molecular Human Reproduction

Volumn 9, Issue 7-8, 2003, Pages 457-464

  Masson, David ^a   Drouineaud, V ^b   Moiroux, P ^a,b   Gautier, T ^a   Dautin, G ^a   Schneider, M ^a   Fruchart Najib, J ^c   Jauhiainen, M ^d   Ehnholm, C ^d   Sagot, P ^b   Gambert, P ^a   Jimenez, C ^b   Lagrost, L ^a  

^a INSERM   (France)

^b HÔPITAL DU BOCAGE   (France)

^c INSTITUT PASTEUR DE LILLE   (France)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

Cholesterol; Cholesteryl ester transfer protein; Phospholipid; Phospholipid transfer protein; Seminal plasma

Indexed keywords

CHOLESTEROL ESTER; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; PHOSPHOLIPID TRANSFER PROTEIN; PROTEIN ANTIBODY;

ARTICLE; CELL MEMBRANE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ANALYSIS; GEL PERMEATION CHROMATOGRAPHY; GERM CELL; HUMAN; LIPID COMPOSITION; MALE; PHOSPHOLIPID TRANSFER; PRIORITY JOURNAL; PROTEIN STRUCTURE; SEMINAL PLASMA; SEMINAL VESICLE; SPERMATOGENESIS; SPERMATOZOON CAPACITATION; SPERMATOZOON MATURATION; WESTERN BLOTTING;

EID: 12444338477     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Albers, J.J., Wolbauer, G., Cheung, M.C., Day, J.R., Ching, A.F.T., Lok, S. and Tu, A.Y. (1995) Functional expression of human and mouse plasma phospholipid transfer protein: effect of recombinant and plasma PLTP on HDL subspecies. Biochim. Biophys Acta, 1258, 27-33.
2. Arienti, G., Saccardi, C., Carlini, E., Verdacchi, R. and Palmerini, C.A. (1999) Distribution of lipid and protein in human semen fractions. Clin. Chim. Acta, 289, 111-120.
3. Bensoussan, K., Morales, C.R. and Hermo, L. (1998) Vitamin E deficiency causes incomplete spermatogenesis and affects the structural differentiation of epithelial cells of the epididymis in the rat. J. Androl., 19, 266-268.
4. Bruce, C., Chouinard, R.A., Jr and Tall, A.R. (1998a) Plasma lipid transfer proteins, high-density lipoproteins and reverse cholesterol transport, Annu. Rev. Nutr., 18, 297-330.
5. Bruce, C., Beamer, L.J. and Tall, A.R. (1998b) The implications of the structure of the bactericidal/permeability-increasing protein on the lipid-transfer function of the cholesteryl ester transfer protein. Curr. Opin. Struct. Biol., 8, 426-434.
6. Cross, N.L. (1998) Role of cholesterol in sperm capacitation. Biol. Reprod., 59, 7-11.
7. Demeester, N., Castro, G., Desrumaux, C., De Geitere, C., Fruchart, J.C., Santens, P., Mulleners, E., Engelborghs, S., De Deyn, P.P., Vandekerckhove, J. et al. (2000) Characterization and functional studies of lipoproteins, lipid transfer proteins and lecithin:cholesterol acyltransferase in CSF of normal individuals and patients with Alzheimer's disease. J. Lipid Res., 4, 963-974.
8. Desnoyers, L. and Manjunath, P. (1992) Major proteins of bovine seminal plasma exhibit novel interactions with phospholipids J. Biol. Chem., 267, 10149-10155.
9. Desrumaux, C., Athias, A., Bessede, G., Verges, B., Farnier, M., Persegol, L, Gambert, P. and Lagrost, L. (1997) Mass concentration of plasma phospholipid transfer protein in normolipidemic, type IIa hyperlipidemic, type IIb hyperlipidemic and non-insulin-dependent diabetic subjects as measured by a specific ELISA. Arterioscler. Thromb. Vasc. Biol., 19, 266-275.
10. Desrumaux, C., Deckert, V., Athias, A., Masson, D., Lizard, G., Palleau, V., Gambert, P. and Lagrost, L. (1999) Plasma phospholipid transfer protein prevents vascular endothelium dysfunction by delivering alpha-tocopherol to endothelial cells. FASEB J., 13, 883-892.
11. Drayna, D., Jarnagin, A., McLean, J., Henzel, W., Kohr, W., Fielding, C. and Lawn, R. (1987) Cloning and sequencing of human cholesteryl ester transfer protein cDNA. Nature, 327, 632-634.
12. Flesch, F.M. and Gadella, B.M. (2000) Dynamics of the mammalian sperm plasma membrane in the process of fertilization. Biochim. Biophys Acta., 10, 197-235.
13. Flesch, F.M., Brouwers, J.F., Nievelstein, P.F., Verkleij, A.J., van Golde, L.M., Colenbrander, B. and Gadella, B.M. (2001) Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholesterol depletion in the sperm plasma membrane. J. Cell Sci., 114, 3543-3555.
14. Fouchecourt, S., Metayer, S., Locatelli, A., Dacbeux, F. and Dacheux, J.L. (2000) Stallion epididymal fluid proteome: qualitative and quantitative characterization; secretion and dynamic changes of major proteins, Biol. Reprod., 62, 1790-1803.
15. Fuentes, J., Miro, J. and Riera, J. (1982) Simple colorimetric method for seminal plasma zinc assay. Andrologia, 14, 322-327.
16. Grizard, G., Bauchard, D., Jouanel, P., Nouailles, C., Jimenez, C. and Boucher, D. (1992) Distribution et composition chimique des lipoprotéines du liquide séminal chez l'homme fertile. Contracept. Fertil. Sex., 20, 8015-8017.
17. Huuskonen, J., Jauhiainen, M., Ehnholm, C. and Olkkonen, V.M. (1998) Biosynthesis and secretion of human plasma phospholipid transfer protein. J. Lipid Res., 39, 2021-2030.
18. Jiang, X.C., Tall, A.R., Qin, S., Lin, M., Schneider, M., Lalanne, F., Deckert, V., Desrumaux, D., Athias, A., Witztum, J.L. et al. (2002) Phospholipid transfer protein (PLTP) deficiency protects circulating lipoproteins from oxidation due to the enhanced accumulation of vitamin E. J. Biol. Chem., 277, 31850-31856.
19. Jones, R. (1998) Plasma membrane structure and remodeling during sperm maturation in the epididymis. J. Reprod. Fertil. Suppl., 53, 73-84.
20. Kirchhoff C., Osterhoff C. and Young L. (1996) Molecular cloning and characterization of HE1, major secretory protein of the human epididymis. Biol. Reprod., 54, 847-856.
21. Lagrost, L., Athias, A., Gambert, P. and Lallemant, C. (1994) Comparative study of phospholipid transfer activities mediated by cholesteryl ester transfer protein and phospholipid transfer protein. J. Lipid Res., 35, 825-835.
22. Lagrost, L., Desrumaux, D., Masson, D., Deckert, V. and Gambert, P. (1998) Structure and function of the plasma phospholipid transfer protein. Curr. Opin. Lipidol., 9, 203-209.
23. Leblond, E., Desnoyers, L. and Manjunath, P. (1993) Phosphorylcholine-binding proteins from the seminal fluids of different species share antigenic determinants with the major proteins of bovine seminal plasma. Mol. Reprod. Dev., 34, 443-449.
24. Lewis, S.E., Sterling, E.S., Young, I.S. and Thompson, W. (1999) Comparison of individual antioxidants of sperm and seminal plasma in fertile and infertile men. Fertil. Steril., 67, 142-147.
25. Lindholmer, C., Carlstrom, A. and Eliasson, R. (1974) Occurrence and origin of proteins in human seminal plasma with special reference to albumin. Andrologia, 6, 181-96.
26. Manjunath, P. and Therien, I. (2002) Role of seminal plasma phospholipid-binding proteins in sperm membrane lipid modification that occurs during capacitation. J. Reprod. Immunol., 53, 109-119.
27. Martínez, P. and Morros, A. (1996) Membrane lipid dynamics during human sperm capacitation Front. Biosci., 1, 103-117.
28. Moreau, R., Franck, P.G., Perreault, C., Marcel, Y.L. and Manjunath, P. (1999) Seminal plasma choline phospholipid-binding proteins stimulate cellular cholesterol and phospholipid efflux. Biochim. Biophys Acta., 19, 38-46.
29. Nishida, H.I. and Nishida, T. (1997) Phospholipid transfer protein mediates transfer of not only phosphatidylcholine but also cholesterol from phosphatidylcholine-cholesterol vesicles to high density lipoproteins. J. Biol. Chem., 272, 2959-2964.
30. Nolan, J.P. and Hammerstedt, R.H. (1997) Regulation of membrane stability and the acrosome reaction in mammalian sperm. FASEB J., 11, 670-682.
31. Okamura, N., Kiuchi, S., Tamba, M., Kashima, T., Hiramoto, S., Baba, T., Dacheux, F., Dacheux J.L., Sugita Y. and Jin, Y.Z. (1999) A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterol. Biochim. Biophys Acta., 19, 377-387.
32. Ravnik, S.E., Zarutski, P.W. and Muller, C.H. (1990) Lipid transfer activity in human follicular fluid: relation to sperm capacitation. J. Androl., 11, 216-226.
33. Ravnik, S.E., Zarutski, P.W. and Muller, C.H. (1992) Purification and characterization of a human follicular fluid lipid transfer protein that stimulates human sperm capacitation. Biol. Reprod., 47, 1126-1133.
34. Ronquist, G. and Brody, I. (1985) The prostasome: its secretion and function in man. Biochim. Biophys Acta, 9, 203-218.
35. Therond, P., Auger, J. and Legrand, A. (1996) Alpha-Tocopherol in human spermatozoa and seminal plasma: relationships with motility, antioxydant enzymes and leukocytes. Mol. Hum. Reprod., 2, 739-744.
36. Van Tol, A. (2002) Phospholipid transfer protein. Curr. Opin. Lipidol., 13, 135-139.
37. Wolfbauer, G., Albers, J.J. and Oram, J.F. (1999) Phospholipid transfer protein enhances removal of cellular cholesterol and phospholipids by high-density lipoprotein apolipoproteins. Biochim. Biophys Acta., 9, 65-76.
38. World Health Organization (1999) Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction, 4th Edn. The Press Syndicate of the University of Cambridge, Cambridge, UK.