Sustained HBs seroconversion during lamivudine and adefovir dipivoxil combination therapy for lamivudine failure

Journal of Hepatology

Volumn 42, Issue 2, 2005, Pages 279-281

  Maynard, Marianne ^a   Parvaz, Parviz ^b   Durantel, Sandra ^c   Chevallier, Michèle ^d   Chevallier, Philippe ^b   Lot, Muriel ^a   Trepo, Christian ^a,c   Zoulim, Fabien ^a,c  

^a HÔTEL DIEU   (France)

^b HOSPICES CIVILS DE LYON   (France)

^c INSERM   (France)

^d Department of Pathology   (France)

Author keywords

Adefovir dipivoxil; Antiviral therapy; Chronic hepatitis; Hepatitis B virus; Lamivudine resistance; Viral clearance

Indexed keywords

ADEFOVIR DIPIVOXIL; HEPATITIS B ANTIBODY; HEPATITIS B SURFACE ANTIGEN; LAMIVUDINE; VIRUS DNA;

ADULT; ANTIBODY TITER; ANTIGEN EXPRESSION; ARTICLE; BLOOD LEVEL; CASE REPORT; CELL COUNT; DNA DETERMINATION; HEPATITIS B; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER FIBROSIS; LIVER HISTOLOGY; MALE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SCORING SYSTEM; SEROCONVERSION; TREATMENT FAILURE; TREATMENT OUTCOME; VIRUS MUTANT;

ADENINE; ADULT; DNA, VIRAL; DRUG THERAPY, COMBINATION; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B, CHRONIC; HUMANS; LAMIVUDINE; MALE; PHOSPHONIC ACIDS; POLYMERASE CHAIN REACTION; TREATMENT FAILURE;

EID: 12444299107     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2004.09.017     Document Type: Article

References (9)

1. C.L. Lai, J. Dienstag, E. Schiff, N.W. Leung, M. Atkins, and C. Hunt Prevalence and clinical correlates of YMDD variants during lamivudine therapy for patients with chronic hepatitis B Clin Infect Dis 36 2003 687 696
2. M.I. Allen, M. Deslauriers, C.W. Andrews, G.A. Tipples, K.A. Walters, and D.L.J. Tyrell Identification and characterization of mutations in hepatitis B virus resistant to lamivudine Hepatology 27 1998 1670 1677
3. R. Perrillo, H.W. Hann, D. Mutimer, B. Willems, N. Leung, and W.M. Lee Adefovir dipivoxil added to ongoing lamivudine in chronic hepatitis B with YMDD mutant hepatitis B virus Gastroenterology 126 2004 81 90
4. M.G. Peters, H. Hann Hw, P. Martin, E.J. Heathcote, P. Buggisch, and R. Rubin Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B Gastroenterology 126 2004 91 101
5. F. Zoulim Treatment of pre- and post-liver transplantation HBV infection: should we aim at combination therapy? Hepatology 38 2003 1353 1355
6. P. Angus, R. Vaughan, S. Xiong, H. Yang, W. Delaney, and C. Gibbs Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase Gastroenterology 125 2003 292 297
7. J.P. Villeneuve, D. Durantel, S. Durantel, C. Westland, S. Xiong, and C.L. Brosgart Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient J Hepatol 39 2003 1085 1089
8. B. Werle-Lapostolle, S. Bowden, S. Locarnini, K. Wursthorn, J. Petersen, and G. Lau Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy Gastroenterology 126 2004 1750 1758
9. L.G. Guidotti, R. Rochford, J. Chung, M. Shapiro, R. Purcell, and F.V. Chisari Viral clearance without destruction of infected cells during acute HBV infection Science 284 1999 825 829