Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: Potent inhibitors of Src tyrosine kinase as novel antiresorptive agents

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 18, 2003, Pages 3071-3074

  Vu, Chi B ^a   Luke, George P ^a   Kawahata, Noriyuki ^a   Shakespeare, William C ^a   Wang, Yihan ^a   Sundaramoorthi, Raji ^a   Metcalf III, Chester A ^a   Keenan, Terence P ^a   Pradeepan, Selvi ^a   Corpuz, Evelyn ^a   Merry, Taylor ^a   Bohacek, Regine S ^a   Dalgarno, David C ^a   Narula, Surinder S ^a   Van Schravendijk, Marie Rose ^a   Ram, Mary K ^a   Adams, Susan ^a   Liou, Shuenn ^a   Keats, Jeffrey A ^a   Violette, Shelia M ^a   Guan, Wei ^a   Weigele, Manfred ^a   Sawyer, Tomi K ^a   more..

^a ARIAD PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE INHIBITOR; PYRIMIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL ASSAY; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; RABBIT; STRUCTURE ACTIVITY RELATION;

EID: 12444257367     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00649-8     Document Type: Article

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