Induced Sputum Inflammatory Mediator Concentrations in Chronic Cough

American Journal of Respiratory and Critical Care Medicine

Volumn 169, Issue 1, 2004, Pages 15-19

  Birring, Surinder S ^a   Parker, Debbie ^a   Brightling, Christopher E ^a   Bradding, Peter ^a   Wardlaw, Andrew J ^a   Pavord, Ian D ^a  

^a GLENFIELD HOSPITAL   (United Kingdom)

Author keywords

Chronic cough; Histamine; Interleukin 8; Prostaglandins; Sputum

Indexed keywords

HISTAMINE; INTERLEUKIN 8; PEPTIDOLEUKOTRIENE; PROSTAGLANDIN D2; PROSTAGLANDIN E2;

ADULT; ARTICLE; ASTHMA; BRONCHITIS; CHRONIC DISEASE; CLINICAL ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; COUGHING; CYTOKINE RELEASE; ENZYME IMMUNOASSAY; EOSINOPHILIA; FEMALE; HISTAMINE RELEASE; HUMAN; IDIOPATHIC DISEASE; MALE; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; SPUTUM ANALYSIS; SPUTUM LEVEL; SUPERNATANT;

EID: 1242345151     PISSN: 00030805     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200308-1092oc     Document Type: Article

References (32)

1. Irwin RS, Madison JM. The diagnosis and treatment of cough. N Engl J Med 2000;343:1715-1721.
2. Brightling CE, Ward R, Goh KL, Wardlaw AJ, Pavord ID. Eosinophilic bronchitis is an important cause of chronic cough. Am J Respir Crit Care Med 1999;160:406-410.
3. McGarvey LP, Heaney LG, Lawson JT, Johnston BT, Scally CM, Ennis M, Shepherd DR, MacMahon J. Evaluation and outcome of patients with chronic non-productive cough using a comprehensive diagnostic protocol. Thorax 1998;53:738-743.
4. Jatakanon A, Lalloo UG, Lim S, Chung KF, Barnes PJ. Increased neutrophils and cytokines, TNF-α and IL-8, in induced sputum of non-asthmatic patients with chronic dry cough. Thorax 1999;54:234-237.
5. Lee SY, Cho JY, Shim JJ, Kim HK, Kang KH, Yoo SH, In KH. Airway inflammation as an assessment of chronic nonproductive cough. Chest 2001;120:1114-1120.
6. McGarvey LP, Forsythe P, Heaney LG, MacMahon J, Ennis M. Bronchoalveolar lavage findings in patients with chronic nonproductive cough. Eur Respir J 1999;13:59-65.
7. Boulet LP, Milot J, Boutet M, St Georges F, Laviolette M. Airway inflammation in nonasthmatic subjects with chronic cough. Am J Respir Crit Care Med 1994;149:482-489.
8. H2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis. J Allergy Clin Immunol 2002;110:899-905.
9. Brightling CE, Bradding P, Symon FA, Holgate ST, Wardlaw AJ, Pavord ID. Mast-cell infiltration of airway smooth muscle in asthma. N Engl J Med 2002;346:1699-1705.
10. 2, bradykinin, and histamine. Am Rev Respir Dis 1989;140:137-141.
11. Gibson PG, Zlatic K, Scott J, Sewell W, Woolley K, Saltos N. Chronic cough resembles asthma with IL-5 and granulocyte-macrophage colony-stimulating factor gene expression in bronchoalveolar cells. J Allergy Clin Immunol 1998;101:320-326.
12. Birring SS, Parker D, Brightling CE, Wardlaw AJ, Pavord ID. Induced sputum inflammatory mediator concentrations in idiopathic chronic cough [abstract]. Am J Respir Crit Care Med 2003;167:A315.
13. Irwin RS, Boulet LP, Cloutier MM, Fuller R, Gold PM, Hoffstein V, Ing AJ, McCool FD, O'Byrne P, Poe RH, et al. Managing cough as a defense mechanism and as a symptom: a consensus panel report of the American College of Chest Physicians. Chest 1998;114:133S-181S.
14. Birring SS, Brightling CE, Symon FA, Barlow SG, Wardlaw AJ, Pavord ID. Idiopathic chronic cough: association with organ specific autoimmune disease and bronchoalveolar lymphocytosis. Thorax (In press).
15. Brightling CE, Ward R, Woltmann G, Bradding P, Sheller JR, Dworski R, Pavord ID. Induced sputum inflammatory mediator concentrations in eosinophilic bronchitis and asthma. Am J Respir Crit Care Med 2000; 162:878-882.
16. Green RH, Brightling CE, McKenna S, Hargadon B, Parker D, Bradding P, Wardlaw AJ, Pavord ID. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 2002;360:1715-1721.
17. Campbell JJ, Murphy KE, Kunkel EJ, Brightling CE, Soler D, Shen Z, Boisvert J, Greenberg HB, Vierra MA, Goodman SB, et al. CCR7 expression and memory T cell diversity in humans. J Immunol 2001; 166:877-884.
18. Pavord ID, Ward R, Woltmann G, Wardlaw AJ, Sheller JR, Dworski R. Induced sputum eicosanoid concentrations in asthma. Am J Respir Crit Care Med 1999;160:1905-1909.
19. Hunter CJ, Ward R, Woltmann G, Wardlaw AJ, Pavord ID. The safety and success rate of sputum induction using a low output ultrasonic nebuliser. Respir Med 1999;93:345-348.
20. Pizzichini MM, Pizzichini E, Clelland L, Efthimiadis A, Mahony J, Dolovich J, Hargreave FE. Sputum in severe exacerbations of asthma: kinetics of inflammatory indices after prednisone treatment. Am J Respir Crit Care Med 1997;155:1501-1508.
21. Sladek K, Dworski R, Soja J, Sheller JR, Nizankowska E, Oates JA, Szczeklik A. Eicosanoids in bronchoalveolar lavage fluid of aspirin-intolerant patients with asthma after aspirin challenge. Am J Respir Crit Care Med 1994;149:940-946.
22. 2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthma. Am Rev Respir Dis 1990;142:126-132.
23. Pizzichini E, Pizzichini MM, Efthimiadis A, Evans S, Morris MM, Squillace D, Gleich GJ, Dolovich J, Hargreave FE. Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements. Am J Respir Crit Care Med 1996;154: 308-317.
24. 4 and granulocytic infiltration into asthmatic airways. Lancet 1993;341:989-990.
25. Schulman ES, MacGlashan DW Jr, Schleimer RP, Peters SP, Kagey-Sobotka A, Newball HH, Lichtenstein LM. Purified human basophils and mast cells: current concepts of mediator release. EurJ Respir Dis Suppl 1983;128:53-61.
26. Tanaka S, Hirata K, Kurihara N, Yoshikawa J, Takeda T. Effect of loratadine, an H1 antihistamine, on induced cough in non-asthmatic patients with chronic cough. Thorax 1996;51:810-814.
27. Rafferty P, Jackson L, Smith R, Holgate ST. Terfenadine, a potent histamine H1-receptor antagonist in the treatment of grass pollen sensitive asthma. Br J Clin Pharmacol 1990;30:229-235.
28. Yosipovitch G, Greaves MW, Schmelz M. Itch. Lancet 2003;361:690-694.
29. Thomas RA, Green RH, Brightling CE, Birring SS, Pavord ID. The influence of age on induced sputum differential cell counts in normal subjects [abstract]. Thorax 2001;56:iii79.
30. Chatkin JM, Ansarin K, Silkoff PE, McClean P, Gutierrez C, Zamel N, Chapman KR. Exhaled nitric oxide as a noninvasive assessment of chronic cough. Am J Respir Crit Care Med 1999;159:1810-1813.
31. Pavord ID, Pizzichini MM, Pizzichini E, Hargreave FE. The use of induced sputum to investigate airway inflammation. Thorax 1997;52: 498-501.
32. Birring SS, Murphy AC, Scullion JE, Brightling CE, Browning M, Pavord ID. Idiopathic chronic cough and organ-specific autoimmune diseases: a case-control study. Respir Med (In press).