The activation of G-protein gated inwardly rectifying K+ channels by a cloned Drosophila melanogaster neuropeptide F-like receptor

European Journal of Neuroscience

Volumn 19, Issue 3, 2004, Pages 570-576

  Reale, Vincenzina ^a   Chatwin, Heather M ^a   Evans, Peter D ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

G protein coupled receptor; Inwardly rectifying potassium channels; mRNA expression; Neuropeptide F; Receptor pharmacology; Xenopus oocyte expression

Indexed keywords

ALPHA TRANSDUCIN; CHLORIDE CHANNEL; G PROTEIN COUPLED RECEPTOR; INWARDLY RECTIFYING POTASSIUM CHANNEL; NEUROPEPTIDE RECEPTOR; PERTUSSIS TOXIN; PROTEIN SUBUNIT; TRANSDUCIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FEMALE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REGULATORY MECHANISM; XENOPUS;

ANIMALS; CHLORIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GENE EXPRESSION; GTP-BINDING PROTEINS; INSECT PROTEINS; ION CHANNEL GATING; MEMBRANE POTENTIALS; NEUROPEPTIDES; OOCYTES; PATCH-CLAMP TECHNIQUES; PEPTIDES; PERTUSSIS TOXIN; POTASSIUM; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, NEUROPEPTIDE; RNA, COMPLEMENTARY; XENOPUS LAEVIS;

EID: 1242317843     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0953-816X.2003.03141.x     Document Type: Article

References (54)

1. Adams, M.D., et al. (2000) The genome sequence of Drosophila melanogaster. Science, 287, 2185-2195.
2. Baggerman, G., Cerstiaens, A., De Loof, A. & Schoofs, L. (2002) Peptidomics of the larval Drosophila melanogaster central nervous system. J. Biol. Chem., 277, 40368-40374.
3. de Bono, M. & Bargmann, C.I. (1998) Natural variation in a Neuropeptide Y receptor homolog modifies social behaviour and food response in C. elegans. Cell, 94, 679-689.
4. Brown, M.R., Crim, J.W., Arata, R.C., Cai, H.N., Chun, C. & Shen, P. (1999) Identification of a Drosophila brain-gut peptide related to the neuropeptide Y family. Peptides, 20, 1035-1042.
5. 1 receptors. Br. J. Pharmacol., 116, 2346-2348.
6. Colmers, W.F., Lukowiak, K. & Pittman, Q.J. (1987) Presynaptic action of neuropeptide Y in area CA1 of the rat hippocampal slice. J. Physiol. (Lond.), 348, 285-299.
7. + channels. Cell Signal., 9, 551-573.
8. Day, T.A. & Maule, A.G. (1999) Parasitic peptides! The structure and function of neuropeptides in parasitic worms. Peptides, 20, 999-1019.
9. Evans, P.D., Robb, S., Cheek, T.R., Reale, V., Hannan, F.L., Swales, L.S., Hall, L.M. & Midgley, J.M. (1995) Agonist-specific coupling of G-protein-coupled receptors to second messenger systems. Prog. Brain Res., 106, 259-268.
10. Feng, G., Reale, V., Chatwin, H., Kennedy, K., Venard, R., Ericsson, C., Yu, K., Evans, P.D. & Hall, L.M. (2003) Functional characterization of a neuropeptide F-like receptor from Drosophila melanogaster. Eur. J. Neurosci., 18, 227-238.
11. Feng, G., Reale, V., Kennedy, K., Chatwin, H.M., Evans, P.D. & Hall, L.M. (1999) Cloning and functional characterization of a novel neuropeptide F-like receptor from Drosophila melanogaster. Soc. Neurosci. Abstr., 25, 183.
12. i-proteins do so in situ. Eur. J. Neurosci., 14, 283-292.
13. Garczynski, S.F., Brown, M.R., Shen, P., Murray, T.F. & Crim, J.W. (2002) Characterization of a functional neuropeptide F receptor from Drosophila melanogaster. Peptides, 23, 773-780.
14. Gaus, G., Doble, K.E., Price, D.A., Greenberg, M.J., Lee, T.D. & Battelle, B.-A. (1993) The sequences of five neuropeptides isolated from Limulus using antisera to FMRFamide. Biol. Bull., 184, 322-329.
15. Grundemar, L. & Hakanson, R. (1994) Neuropeptide Y effector systems: perspectives for drug development. Trends Pharmacol. Sci., 15, 153-159.
16. Hall, L.M., Evans, P.D. & Yu, K. (2000) RNA expression pattern of a neuropeptide F-like receptor in Drosophila embryos and larval central nervous system. Soc. Neurosci. Abstr., 26, 915.
17. Hewes, R.S. & Taghert, P.H. (2001) Neuropeptides and neuropeptide receptors in the Drosophila melanogaster genome. Genome Res., 11, 1126-1142.
18. Ingenhoven, N. & Beck-Sickinger, A.G. (1999) Molecular characterization of the ligand-receptor interaction of neuropeptide Y. Curr. Med. Chem., 6, 1055-1066.
19. Inui, A. (1999) Neuropeptide Y feeding receptors: are multiple subtypes involved? Trends Pharmacol. Sci., 20, 43-46.
20. de Jong-Brink, M., Ter Maat, A. & Tenson, C.P. (2001) NPY in invertebrates: molecular answers to altered functions during evolution. Peptides, 22, 309-315.
21. Kenakin, T. (1995) Agonist-receptor efficacy II: agonist trafficking of receptor signals. Trends Pharmacol. Sci., 16, 232-238.
22. Kurachi, Y. (1995) G-proetin regulation of cardiac muscarinic potassium channel. Am. J. Physiol., 269, C821-C830.
23. Larhammer, D. (1996) Structural diversity of receptors for neuropeptide Y, peptide YY and pancreatic polypeptide. Regul. Peptides, 62, 1-11.
24. + channels. J. Biol. Chem., 275, 921-929.
25. Littleton, J.T. & Ganetzky, B. (2000) Ion channels and synaptic organization: analysis of the Drosophila genome. Neuron, 26, 35-43.
26. Maule, A.G., Halton, D.W. & Shaw, C. (1995) Neuropeptide F: a ubiquitous invertebrate neuromediator? Hydrobiologia, 305, 297-303.
27. Mertens, I., Meeusen, T., Huybrechts, R., De Loof, A. & Schoofs, L. (2002) Characterization of the short neuropeptide F receptor from Drosophila melanogaster. Biochim. Biophys. Res. Commun., 297, 1140-1148.
28. 16 as a universal G protein adapter: implications for agonist screening strategies. Trends Pharmacol. Sci., 17, 235-237.
29. Nassel, D.R. (1993) Neuropeptides in the insect brain: a review. Cell Tissue Res., 273, 1-29.
30. Pfaff, T. & Karschin, A. (1997) Expression cloning of rat cerebellar adenosine A1 receptor by coupling to Kir channels. Neuroreport, 8, 2455-2460.
31. Rajpara, S.M., Gaecia, P.D., Roberts, R., Eliassen, J.C., Owens, D.F., Maltby, D., Myers, R.M. & Mayeri, E. (1992) Identification and molecular cloning of a Neuropeptide Y homolog that produces prolonged inhibition in Aplysia neurons. Neuron, 9, 505-513.
32. Reale, V., Chatwin, H.M., Evans, P.D. & de Bono, M. (2002) The identification of endogenous ligands for the C. elegans Neuropeptide receptor, NPR-1. Soc. Neurosci. Abstr., 28, 544.13.
33. Reale, V., Chatwin, H.M., Hall, L.M. & Evans, P.D. (2000) The action of endogenous Neuropeptide F-like peptides on a cloned Neuropeptide F-like receptor from Drosophila melanogaster. Soc. Neurosci. Abstr., 26, 915.
34. Reale, V., Hannan, F., Hall, L.M. & Evans, P.D. (1997) Agonist-specific coupling of a cloned Drosophila melanogaster D1-like dopamine receptor to multiple second messenger pathways by synthetic agonists. J. Neurosci., 17, 6545-6553.
35. Remy, C., Guy, J., Pelletier, G. & Boer, H.H. (1988) Immunohistochemical demonstration of a substance related to neuropeptide Y and FMRFarmide in the cephalic and thoracic nervous systems of the locust, Locusta migratoria. Cell Tissue Res., 254, 189-195.
36. 2 receptor for Neuropeptide Y. Mol. Pharmacol., 49, 387-390.
37. Robb, S., Cheek, T.R., Hannan, F.L., Hall, L.M., Midgley, J.M. & Evans, P.D. (1994) Agonist-specific coupling of a cloned Drosophila octopamine/ tyramine receptor to multiple second messenger systems. EMBO J., 13, 1325-1330.
38. Rogers, C., Reale, V., Kim, K., Chatwin, H., Li, C., Evans, P. & de Bono, M. (2003) Inhibition of Caenorhabditis elegans social feeding by FMRFamide-related peptide activation of NPR-1. Nature Neurosci., 6, 1178-1185.
39. Schoofs, L., Danger, J.M., Jegou, S., Pelletier, G., Huybrechts, R., Vaudry, H. & De Loof, A. (1988) NPY-like peptides occur in the nervous system and midgut of the migratory locust, Locusta migratoria, and in the brain of the grey flesh fly, Sarcophaga bullata. Peptides, 9, 1027-1036.
40. Shen, P. & Cai, H.N. (2001) Drosophila Neuropeptide F mediates integration of cheomsensory stimulation and conditioning of the nervous system by food. J. Neurobiol., 47, 16-25.
41. + channel. J. Biol. Chem., 271, 30524-30528.
42. Smart, D., Shaw, C., Johnston, C., Thim, L., Halton, D. & Buchanan, K. (1992) Peptide tyrosine phenylalanine: a novel neuropeptide F-related nonapeptide from the brain of the squid, Loligo vulgaris. Biochem. Biophys. Res. Commun., 186, 1616-1623.
43. Spittaels, K., Verhaert, P., Shaw, C., Johnston, R.N., Devreese, B., Van Beeumen, J. & De Loof, A. (1996) Insect Neuropeptide F (NPF)-related peptides: isolation from Colorado potato beetle (Leptinotarsa decemlineata) brain. Insect Biochem. Mol. Biol., 26, 375-382.
44. Stables, J., Green, A., Marshall, F., Fraser, N., Knight, E., Sautel, M., Milligan, G., Lee, M. & Rees, S. (1997) A bioluminescent assay for agonist activity at potentially any G-protein-couple receptor. Anal. Biochem., 252, 115-126.
45. ++ channels by a family of neuropeptide Y receptors. J. Pharm. Exp. Therap., 284, 625-632.
46. Tensen, C.P., Cox, K.J.A., Smit, A.B., van der Schors, R.C., Meyerhof, W., Richter, D., Planta, R.J., Hermann, P.M., van Minnen, J., Geraerts, W.P.M., Knol, J.C., Burke, J.F., Vreugdenhil, E. & van Heerikhuizen, H. (1998) The Lymnaea cardioexcitatory peptide (LyCep) receptor: a G-protein-coupled receptor for a novel member of the RFamide neuropeptide family. J. Neurosci., 18, 9812-9821.
47. Van Renterghem, C., Bilbe, G., Moss, S., Smart, T.G., Constanti, A., Brown, D.A. & Barnard, E.A. (1987) GABA receptors induced in Xenopus oocytes by chick brain messenger RNA: evaluation of TBPS as a use dependent channel blocker. Mol. Brain Res., 2, 21-31.
48. Vanden Broeck, J. (2001) Neuropeptides and their precursors in the fruitfly, Drosophila melanogaster. Peptides, 22, 241-254.
49. Verhaert, P., Maule, A.G., Shaw, C., Halton, D.W., Callaerts, P. & De Loof, A. (1993) Dual location of neuropeptide F in the central nervous system and midgut of the fruit-fly Drosophila melanogaster. Belg. J. Zool., 123 (Suppl. 1), 86.
50. Verhaert, P., Maule, A.G., Shaw, C., Halton, D., Thim, L. & De Loof, A. (1994) Purification and partial characterization of neuropeptide F-like material from the neuroendocrine system of an insect. In Borkovec, A.B. & Loeb, M.J. (Eds), Insect Neurochemistry and Neurophysiology 1993. CRC Press, Boca Raton, FL, pp. 311-314.
51. Wahlestedt, C. & Reis, D.J. (1993) Neuropeptide Y-related peptides and their receptors: are the receptors potential therapeutic drug targets? Annu. Rev. Pharmacol. Toxicol., 32, 309-352.
52. Wickman, K.D. & Clapham, D.E. (1995) Ion channel regulation by G-proteins. Physiol. Rev., 75, 865-885.
53. Wu, Q., Wen, T., Lee, G., Park, J.H., Cai, H.N. & Shen, P. (2003) Developmental control of foraging and social behaviour by the Drosophila Neuropeptide Y-like system. Neuron, 39, 147-161.
54. Yamada, M., Inanobe, A. & Kurachi, Y. (1998) G protein regulation of potassium ion channels. Pharmacol. Rev., 50, 723-757.