A Membrane Transport Defect Leads to a Rapid Attenuation of Translation Initiation in Saccharomyces cerevisiae

Molecular Cell

Volumn 13, Issue 3, 2004, Pages 357-366

  Deloche, Olivier ^a   De La Cruz, Jesús ^b   Kressler, Dieter ^a,c   Doère, Monique ^a   Linder, Patrick ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITY OF SEVILLE   (Spain)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORPROMAZINE; EIF4E ASSOCIATED PROTEIN EAP1; EIF4E-ASSOCIATED PROTEIN EAP1; GCN2 PROTEIN KINASE; HCS77 PROTEIN; INITIATION FACTOR; MEMBRANE PROTEIN; MUTANT PROTEIN; PROTEIN KINASE; PROTEIN KINASE C; RIBOSOME PROTEIN; TRANSFER RNA; VESICULAR TRANSPORT PROTEIN;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CONTROLLED STUDY; DRUG EFFECT; GENETICS; INTRACELLULAR MEMBRANE; MEMBRANE TRANSPORT; METABOLISM; MICROBIAL ATTENUATION; MUTATION; NONHUMAN; PHYSIOLOGY; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION; PROTEIN TRANSPORT; RIBOSOME; RNA TRANSLATION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION; TRANSLATION INITIATION; TRANSPORT VESICLE;

EUKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 1242316948     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(04)00008-5     Document Type: Article

References (40)

1. Altmann M., Schmitz N., Berset C., Trachsel H. A novel inhibitor of cap-dependent translation initiation in yeast. p20 competes with eIF4G for binding to eIF4E EMBO J. 16:1997;1114-1121.
2. Ashe M.P., De Long S.K., Sachs A.B. Glucose depletion rapidly inhibits translation initiation in yeast. Mol. Biol. Cell. 11:2000;833-848.
3. Ashe M.P., Slaven J.W., De Long S.K., Ibrahimo S., Sachs A.B. A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols. EMBO J. 20:2001;6464-6474.
4. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., and Struhl, K. (1994). Saccharomyces cerevisiae. In Current Protocols in Molecular Biology (New York: John Wiley & Sons, Inc.), pp. 13.10.11-13.14.17.
5. Barbet N.C., Schneider U., Helliwell S.B., Stansfield I., Tuite M.F., Hall M.N. TOR controls translation initiation and early G1 progression in yeast. Mol. Biol. Cell. 7:1996;25-42.
6. Benedetti H., Raths S., Crausaz F., Riezman H. The END3 gene encodes a protein that is required for the internalization step of endocytosis and for actin cytoskeleton organization in yeast. Mol. Biol. Cell. 5:1994;1023-1037.
7. Berset C., Trachsel H., Altmann M. The TOR (target of rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA. 95:1998;4264-4269.
8. Cherkasova V.A., Hinnebusch A.G. Translation control by TOR and TAP42 through dephosphorylation of eIF2α kinase GCN2. Genes Dev. 17:2003;859-872.
9. Conibear E., Stevens T.H. Multiple sorting pathways between the late Golgi and the vacuole in yeast. Biochim. Biophys. Acta. 1404:1998;211-230.
10. Cosentino G.P., Schmelzle T., Haghighat A., Helliwell S.B., Hall M.N., Sonenberg N. Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae. Mol. Cell. Biol. 20:2000;4604-4613.
11. de la Cruz J., Iost I., Kressler D., Linder P. The p20 and Ded1 proteins have antagonistic roles in eIF4E-dependent translation in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA. 94:1997;5201-5206.
12. de la Cruz J., Kressler D., Tollervey D., Linder P. Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3′ end formation of 5.8S rRNA in Saccharomyces cerevisiae. EMBO J. 17:1998;1128-1140.
13. Dever T.E. Gene-specific regulation by general translation factors. Cell. 108:2002;545-556.
14. Dever T.E., Feng L., Wek R.C., Cigan A.M., Donahue T.F., Hinnebusch A.G. Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast. Cell. 68:1992;585-596.
15. Di Como C.J., Arndt K.T. Nutrients, via the TOR proteins, stimulate the association of Tap42 with type 2A phosphatases. Genes Dev. 10:1996;1904-1916.
16. Gingras A.C., Raught B., Sonenberg N. eIF4 initiation factors. effectors of mRNA recruitment to ribosomes and regulators of translation Annu. Rev. Biochem. 68:1999;913-963.
17. Goossens A., Dever T.E., Pascual-Ahuir A., Serrano R. The protein kinase Gcn2p mediates sodium toxicity in yeast. J. Biol. Chem. 276:2001;30753-30760.
18. Harding H.P., Calfon M., Urano F., Novoa I., Ron D. Transcriptional and translational control in the mammalian unfolded protein response. Annu. Rev. Cell Dev. Biol. 18:2002;575-599.
19. 3H]glycerol in the primordial placenta. Placenta. 16:1995;347-358.
20. Hershey J.W.B., Merrick W.C. The pathway and mechanism of initiation of protein synthesis. Sonenberg N., Hershey J.W.B., Mathews M.B. Translational Control of Gene Expression. 2000;33-88 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
21. Hinnebusch A.G. Mechanism and regulation of initiator methionyl-tRNA binding to ribosomes. Sonenberg N., Hershey J.W.B., Mathews M.B. Translational Control of Gene Expression. 2000;185-244 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
22. Kamada Y., Jung U.S., Piotrowski J., Levin D.E. The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response. Genes Dev. 9:1995;1559-1571.
23. Kim C.H., Warner J.R. Mild temperature shock alters the transcription of a discrete class of Saccharomyces cerevisiae genes. Mol. Cell. Biol. 3:1983;457-465.
24. Kushnirov V.V. Rapid and reliable protein extration from yeast. Yeast. 16:2000;857-860.
25. Letourneur F., Gaynor E.C., Hennecke S., Demolliere C., Duden R., Emr S.D., Riezman H., Cosson P. Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum. Cell. 79:1994;1199-1207.
26. Li Y., Moir R.D., Sethy-Coraci I.K., Warner J.R., Willis I.M. Repression of ribosome and tRNA synthesis in secretion-defective cells is signaled by a novel branch of the cell integrity pathway. Mol. Cell. Biol. 20:2000;3843-3851.
27. Mizuta K., Warner J.R. Continued functioning of the secretory pathway is essential for ribosome synthesis. Mol. Cell. Biol. 14:1994;2493-2502.
28. Natarajan K., Meyer M.R., Jackson B.M., Slade D., Roberts C., Hinnebusch A.G., Marton M.J. Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast. Mol. Cell. Biol. 21:2001;4347-4368.
29. Nelson K.K., Lemmon S.K. Suppressors of clathrin deficiency. overexpression of ubiquitin rescues lethal strains of clathrin-deficient Saccharomyces cerevisiae Mol. Cell. Biol. 13:1993;521-532.
30. Nierras C.R., Warner J.R. Protein kinase C enables the regulatory circuit that connects membrane synthesis to ribosome synthesis in Saccharomyces cerevisiae. J. Biol. Chem. 274:1999;13235-13241.
31. Novick P., Schekman R. Secretion and cell surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA. 76:1979;1858-1862.
32. Novick P., Field C., Schekman R. Identification of 23 complementation groups required for posttranslational events in the yeast secretory pathway. Cell. 21:1980;205-215.
33. Poulin F., Gingras A.C., Olsen H., Chevalier S., Sonenberg N. 4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family. J. Biol. Chem. 273:1998;14002-14007.
34. Rolfes R.J., Hinnebusch A.G. Translation of the yeast transcriptional activator GCN4 is stimulated by purine limitation. implications for activation of the protein kinase GCN2 Mol. Cell. Biol. 13:1993;5099-5111.
35. Rothman J.E., Orci L. Molecular dissection of the secretory pathway. Nature. 355:1992;409-415.
36. Shulman R.W., Sripati C.E., Warner J.R. Noncoordinated transcription in the absence of protein synthesis in yeast. J. Biol. Chem. 252:1977;1344-1349.
37. Simons K., Toomre D. Lipid rafts and signal transduction. Nat. Rev. Mol. Cell Biol. 1:2000;31-39.
38. Stuhne-Sekalec L., Chudzik J., Stanacev N.Z. Effect of chlorpromazine on the synthesis, hydrolysis and transfer of microsomal cytidine liponucleotide and mitochondrial polyglycerophosphatides. Can. J. Physiol. Pharmacol. 65:1987;377-384.
39. Toker A. Phosphoinositides and signal transduction. Cell. Mol. Life Sci. 59:2002;761-779.
40. Yang R., Wek S.A., Wek R.C. Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase. Mol. Cell. Biol. 20:2000;2706-2717.