Hippocampal gene expression is modulated by hypergravity

European Journal of Neuroscience

Volumn 19, Issue 3, 2004, Pages 667-677

  Del Signore, A ^a   Mandillo, S ^a   Rizzo, A ^a   Di Mauro, E ^a   Mele, A ^a   Negri, R ^a   Oliverio, A ^a   Paggi, P ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

cDNA microarrays; Mice; Neuronal plasticity; Rotation; Stress

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; INHIBIN; MESSENGER RNA; THYMOSIN BETA10;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE; CELL FUNCTION; CELL MOTILITY; CELL STRUCTURE; CENTRIFUGE; CONTROLLED STUDY; CYTOSKELETON; DNA METABOLISM; DNA MICROARRAY; DOWN REGULATION; ENVIRONMENTAL CHANGE; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC CODE; GRAVITY; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL; NERVE CELL PLASTICITY; NEUROBLASTOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN PROCESSING; RNA METABOLISM; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; UNINDEXED SEQUENCE; UPREGULATION;

ANIMALS; CENTRIFUGATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HYPERGRAVITY; MALE; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 1242295332     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0953-816X.2004.03171.x     Document Type: Article

References (55)

1. Becker, K.G., Wood, W.H. III & Cheadle, C. (2003) DNA microarrays on membranes. In Bowtell, D. & Sambrook, J. (Eds), DNA Microarrays: Molecular Cloning Manual. CSHL Press, Cold Spring Harbor, NY, pp. 289-303.
2. Birnberg, N.C., Lissitzky, J.C., Hinman, M. & Herbert, E. (1983) Glucocorticoids regulate proopiomelanocortin gene expression in vivo at the levels of transcription and secretion. Proc. Natl Acad. Sci. USA, 80, 6982-6986.
3. Braun, J.E.A. & Madison, D.V. (2000) A novel SNAP25-Caveolin complex correlates with the onset of persistent synaptic potentiation. J. Neurosci., 20, 59997-56006.
4. Cai, Q., Liu, H.J., Zhan, Z. & Zhu, M.C. (2000) A study of apoptosis and related gene bcl-2 and p53 expression in hippocampus of rats exposed to repeated +Gz. Space Med. Med. Eng. (Beijing), 13, 263-266.
5. Carpintero, P., Anadón, R. & Gómez-Márquez, J. (1999) Expression of the thymosin beta-10 gene in normal and kainic acid-treated rat forebrain. Mol. Brain Res., 70, 141-146.
6. Cavallaro, S., D'Agata, V., Manickam, P., Dufour, F. & Alkon, D.L. (2002) Memory-specific temporal profiles of gene expression in the hippocampus. Proc. Natl Acad. Sci. USA, 99, 16279-16284.
7. Chabbert, C., Brugeaud, A., Lennan, G., Lehouelleur, J. & Sans, A. (2003) Electrophysiological properties of the utricular primary transducer are modified during development under hypergravity. Eur. J. Neurosci., 17, 2497-2500.
8. Christopoulos, G., Perry, K.J., Morfis, M., Tilakaratne, N., Gao, Y., Fraser, N.J., Main, M.J., Foord, S.M. & Sexton, P.M. (1999) Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product. Mol. Pharmacol., 56, 235-242.
9. Cox, J.F., Tahvanainen, K.U., Kuusela, T.A., Levine, B.D., Cooke, W.H., Mano, T., Iwase, S., Saito, M., Sugiyama, Y., Ertl, A.C., Biaggioni, I., Diedrich, A., Robertson, R.M., Zuckerman, J.H., Lane, L.D., Ray, C.A., White, R.J., Pawelczyk, J.A., Buckey, J.C.J., Baisch, F.J., Blomqvist, C.G., Robertson, D. & Eckberg, D.L. (2002) Influence of microgravity on astronauts' sympathetic and vagal responses to Valsalva's manoeuvre. J. Physiol., 538, 309-320.
10. Durzan, D.J., Ventimiglia, F. & Havel, L. (1998) Taxane recovery from cells of Taxus in micro-and hypergravity. Acta Astronaut., 42, 455-463.
11. Feldman, S. & Conforti, N. (1980) Participation of the dorsal hippocampus in the glucocorticoid feedback effect on adrenocortical activity. Neuroendocrinology, 30, 52-55.
12. Fields, R.D. & Stevens-Graham, B. (2002) New insights into neuron-glia communication. Science, 298, 556-562.
13. Fifkovà, E. (1985) Actin in the nervous system. Brain Res., 356, 187-215.
14. Fitzgerald, J. & Hughes-Fulford, M. (1996) Gravitational loading of a simulated launch alters mRNA expression in osteoblasts. Exp. Cell. Res., 228, 168-171.
15. Fowler, B., Comfort, D. & Bock, O. (2000) A review of cognitive and perceptual-motor performance in space. Aviat. Space Environ. Med., 71, A66-A68.
16. Fricker, L.D., McKinzie, A.A., Sun, J., Curran, E., Qiam, Y., Yan, L., Patterson, S.D., Courchesne, P.L., Richards, B., Levin, N., Mzhavia, N., Devi, L.A. & Douglass, J. (2000) Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing. J. Neurosci., 20, 639-648.
17. Gharib, C. & Custaud, M.A. (2002) Orthostatic tolerance after spaceflight or simulated weightlessness by head-down bed-rest. Bull. Adac. Natl Med., 186, 733-749.
18. Guinan, M.J., Horowitz, J.M. & Fuller, C.A. (1998) Effects of hyperdynamic fields on input-output relationships and long-term potentiation in the rat hippocampus. J. Gravit. Physiol., 5, 31-40.
19. Gustave Dit Duflo, S., Gestreau, C. & Lacour, M. (2000) Fos expression in the rat brain after exposure to gravito-inertial force changes. Brain Res., 861, 333-344.
20. Herman, J.P., Schafer, M.K.-H., Young, E.A., Thompson, R., Douglass, J., Akil, H. & Watson, S.J. (1989) Evidence for hippocampal regulation of neuroendocrine neurons on the hypothalamo-pituitary-adrecocortical axis. J. Neurosci., 9, 3072-3082.
21. Ikegaya, Y., Saito, H., Torii, K. & Nishiyama, N. (1997) Activin selectively abolishes hippocampal long-term potentiation induced by weak titanic stimulation in vivo. Jpn. J. Pharmacol., 75, 87-89.
22. Ilyin, E.A. & Oganov, V.S. (1989) Microgravity and musculoskeletal system of mammals. Adv. Space Res., 9, 11-19.
23. Inokuchi, K., Kato, A., Hiraia, K., Hishinuma, F., Inoue, M. & Ozawa, F. (1996) Increase in activin beta A mRNA in rat hippocampus during long-term potentiation. FEBS Lett., 382, 48-52.
24. Irwin, L.N. (2001) Gene expression in the hippocampus of behaviourally stimulated rats: analysis by DNA microarray. Mol. Brain Res., 96, 163-169.
25. Iwahori, Y., Saito, H., Torii, K. & Nishiyama, N. (1997) Activin exerts a neurotrophic effect on cultured hippocampal neurons. Brain Res., 760, 52-58.
26. Jouvert, P., Dietrich, J.B., Aunis, D. & Zwiller, J. (2002) Differential rat brain expression of EGR proteins in response to acute or chronic cocaine administration. Neuromolecular Med., 1, 137-151.
27. Knierim, J.J., McNaughton, B.L. & Poe, G.R. (2000) Three-dimensional spatial selectivity of hippocampal neurons during space flight. Nat. Neurosci., 3, 209-210.
28. Krude, H. & Gruters, A. (2000) Implications of proopiomelanocortin (POMC) mutations in humans: the POMC deficency syndrome. Trends Endocrinol. Metab., 1, 15-22.
29. Lewis, M.L. & Hughes-Fulford, M. (2000) Regulation of heat shock protein message in Jukart cells cultured under serum-starved and gravity-altered conditions. J. Cell. Biochem., 77, 127-134.
30. Lin, S.C. & Morrison-Bogorad, M. (1990) Developmental expression of mRNAs encoding thymosins beta 4 and beta 10 in rat brain and other tissues. J. Mol. Neurosci., 2, 35-44.
31. Liu, H.J., Cai, Q., Ji, G.Y., Zhan, Z., Jiang, J.D. & Zhu, M.C. (2000) Changes of mRNA expression of IL-1beta and TNF-alpha in rat brains after repeated exposures to +Gz. Space Med. Med. Eng. (Beijing), 13, 371-373.
32. Maccarrone, M., Putti, S. & Finazzi Agro, A. (1998) Altered gravity modulates 5-lipoxygenase in human erythroleukemia K562 cells. J. Gravit. Physiol., 5, 97-98.
33. Mandillo, S., Del Signore, A., Paggi, P., Francia, N., Santucci, D., Mele, A. & Oliverio, A. (2003) Effects of acute and repeated daily exposure to hypergravity on spatial learning in mice. Neurosci. Lett., 336, 147-150.
34. Manzey, D. & Lorenz, B. (1998) Mental performance during short-term and long-term spaceflight. Brain Res. Rev., 28, 215-221.
35. Meyer, A., Chrètien, P., Massicotte, G., Sargent, C., Chrètien, M. & Marcinkiewicz, M. (1996) Kainic acid increases the expression of the prohormone convertases furin and PC1 in the mouse hippocampus. Brain Res., 732, 121-132.
36. Murakami, D.M., Tang, I.H. & Fuller, C.A. (1998) Chronic 2g exposure affects c-Fos reactivity to a light pulse within the rat suprachiasmatic nucleus. J. Gravit. Physiol., 5, 71-78.
37. Nose, K. & Shibanuma, M. (1994) Induction of early response genes by hypergravity in cultured mouse osteoblastic cells (MC3T3-E1). Exp. Cell. Res., 211, 168-170.
38. Phillips, L.L. & Belardo, E.T. (1994) Incrase of c-fos and ras oncoproteins in the denervated neuropil of the rat dentate gyrus. Neuroscience, 58, 503-514.
39. Pompeiano, M., D'Ascanio, P., Centini, C., Pompeiano, O., Cirelli, C. & Tononi, G. (2001a) Immediate early gene expression in the vestibular nuclei and related vegetative areas in rats during space flight. Acta Otolaryngol., 545, 120-126.
40. Pompeiano, M., D'Ascanio, P., Centini, C., Pompeiano, O., Cirelli, C. & Tononi, G. (2001b) Fos-related antigens are involved in the transcriptional responses of locus coeruleus neurons to altered gravitational fields in rats. Acta Otolaryngol., 545, 127-132.
41. Porro, C.A., Cavazzuti, M., Baraldi, P., Giuliani, D., Panerai, A.E. & Corazza, R. (1999) CNS pattern of metabolic activity during tonic pain: evidence for modulation by beta-endorphin. Eur. J. Neurosci., 11, 874-888.
42. Quackenbush, J. (2002) Microarray data normalization and transformation. Nat. Genet., 32, 496-501.
43. Rahmann, H., Slenzka, K., Kortje, K.J. & Hilbig, R. (1992) Synaptic plasticity and gravity: ultrastructural, biochemical and physico-chemical fundaments. Adv. Space Res., 12, 63-72.
44. Santucci, D., Corazzi, G., Francia, N., Antonelli, A., Aloe, L. & Alleva, E. (2000) Neurobehavioural effects of hypergravity conditions in the adult mouse. Neuroreport, 11, 3353-3356.
45. Seidah, N.G., Benjannet, S., Pareek, S., Chrètien, M. & Murphy, R.A. (1996) Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases. FEBS Lett., 379, 247-250.
46. Shahed, A.R., Son, M., Lee, J.C. & Werchan, P.M. (1996) Expression of c-fos, c-jun and HSP70 mRNA in rat brain following high acceleration stress. J. Gravit. Physiol., 3, 49-56.
47. Stackman, R.W., Clark, A.S. & Taube, J.S. (2002) Hippocampal spatial representations require vestibular input. Hippocampus, 12, 291-303.
48. Sun, X.Q., Li, J. & Wu, X. Y. (2002) Effects of repeated +Gz exposures on the expression of c-fos protein in rabbit brain. Space Med. Med. Eng. (Beijing), 15, 17-21.
49. Svaren, J., Sevetson, B.R., Apel, E.D., Zimonjic, D.B., Popescu, N.C. & Milbrandt, J. (1996) NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli. Mol. Cell. Biol., 16, 3545-3553.
50. Ullian, E.M., Sapperstein, S.K., Christopherson, K.S. & Barres, B.A. (2001) Control of synapse number by glia. Science, 291, 657-661.
51. Uno, Y., Horii, A., Uno, A., Fuse, Y., Fukushima, M., Doi, K. & Kubo, T. (2002) Quantitative changes in mRNA expression of glutamate receptors in the rat peripheral and central vestibular systems following hypergravity. J. Neurochem., 81, 1308-1317.
52. Walker, J. & Rigley, K. (2000) Gene expression profiling in human peripheral blood cells using high density filter-based cDNA microarrays. J. Immunol. Methods, 239, 167-179.
53. Wang, G., Witkin, J.W., Hao, G., Bankaitis, V.A., Scherer, P.E. & Baldini, G. (1997) Syndet is a novel SNAP-25 related protein expressed in many tissues. J. Cell Sci., 110, 505-513.
54. Yoshioka, R., Soga, K., Wakabayashi, K., Takeba, G. & Hoson, T. (2001) Hypergravity-induced changes in gene expression in Arabidopsis. Biol. Sci. Space, 15, 260-261.
55. Young, L.R. (1995) Effects of orbital space flight on vestibular reflexes and perception. Acta Astronaut., 36, 409-413.