Association of oestrogen receptor alpha gene polymorphism with the angiographic extent of coronary artery disease

European Heart Journal

Volumn 25, Issue 3, 2004, Pages 240-245

  Pollak, Arthur ^a   Rokach, Ariel ^a   Blumenfeld, Anat ^a   Rosen, Laura J ^b   Resnik, Luba ^a   Pollak, Rivka Dresner ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Angiography; Coronary artery disease; Oestrogen receptor gene polymorphism; Risk factors

Indexed keywords

ADENINE; ESTROGEN RECEPTOR ALPHA; THYMINE;

ADULT; AGE; AGED; ALLELE; ANGIOGRAPHY; ARTICLE; BASE PAIRING; CORONARY ARTERY DISEASE; CORONARY BLOOD VESSEL; DINUCLEOTIDE REPEAT; DISEASE SEVERITY; EXON; FEMALE; GENDER; GENETIC POLYMORPHISM; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; POISSON DISTRIBUTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RISK FACTOR; VASOCONSTRICTION;

ADULT; AGED; AGED, 80 AND OVER; CORONARY ANGIOGRAPHY; CORONARY ARTERIOSCLEROSIS; ESTROGEN RECEPTOR ALPHA; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RECEPTORS, ESTROGEN;

EID: 1242272036     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ehj.2003.10.028     Document Type: Article

References (31)

1. Farhat MY, Lvigne MC, Ramwell PW. The vascular protective effects of estrogen. FASEB J 1996;10:615-24.
2. Gruber CJ, Tschugguel W, Schneeberger C et al. Production and actions of estrogens. N Engl J Med 2002;346:340-52.
3. Women's Health Initiative Trial. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 2002;288:321-33.
4. Manson JE, Hsia J, Johnson KC et al. Estrogen and Progestin and the risk of coronary heart disease. N Engl J Med 2003;349:523-34.
5. Hodis HN, Mack WJ, Azen SP et al. Hormone therapy and the progression of coronary-artery atherosclerosis in postmenopausal women. N Engl J Med 2003;349:535-45.
6. Mendelsohn ME. Genomic and nongenomic effects of estrogen in the vasculture. Am J Cardiol 2002;90(1A):3F-6F.
7. Hodgin JB, Krege JH, Reddick RL et al. Estrogen receptor α is a major mediator of 17β-estradiol's atheroprotective effects on lesion size in Apoe-/- mice. J Clin Invest 2001;107:333-40.
8. Losordo DW, Kearney M, Kim EA et al. Variable expression of the estrogen receptor in normal and atherosclerotic coronary arteries of premenopausal women. Circulation 1994;89:1501-10.
9. Post WS, Goldschmidt-Clermont PJ, Wilhide CC et al. Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system. Cardiovasc Res 1999;43: 985-91.
10. Sudhir K, Chou TM, Chatterjee K et al. Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man. Circulation 1997;96:3774-7.
11. Andersen TI, Heimdal KR, Skrede M et al. Oestrogen receptor (ESR) polymorphisms and breast cancer susceptibility. Hum Genet 1994;94:665-70.
12. Kobayashi S, Inoue S, Hosoi T et al. Association of bone mineral density with polymorphism of the estrogen receptor gene. J Bone Miner Res 1996;11:306-11.
13. Sano M, Inoue S, Hosoi T et al. Association of estrogen receptor dinucleotide repeat polymorphism with osteoporosis. Biochem Biophys Res Commun 1995;217:378-83.
14. Becherini L, Gennari L, Masi L et al. Evidence of a linkage disequilibrium between polymorphisms in the human estrogen receptor a gene and their relationship to bone mass variation in postmenopausal Italian women. Hum Mol Genet 2000;9:2043-50.
15. Lehrer S, Rabin J, Kalir T et al. Estrogen receptor variant and hypertension in women. Hypertension 1993;21:439-41.
16. Matsubara Y, Murata M, Kawano K et al. Genotype distribution of estrogen receptor polymorphisms in men and postmenopausal women from healthy and coronary populations and its relation to serum lipid levels. Arterioscler Thromb Vasc Biol 1997;17:3006-12.
17. Herrington DM, Howard TD, Hawkins GA et al. Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease. N Engl J Med 2002;346:967-74.
18. Lehtimaki T, Kunnas TA, Mattila KM et al. Coronary artery wall atherosclerosis in relation to the estrogen receptor 1 gene polymorphism: an autopsy study. J Mol Med 2002;80:176-80.
19. Kunnas TA, Laippala P, Penttila A et al. Association of polymorphism of human α oestrogen receptor gene with coronary artery disease in men: a necropsy study. BMJ 2000;321:273-4.
20. Lu H, Higashikata T, Inazu A et al. Association of estrogen receptor-α gene polymorphisms with coronary artery disease in patients with familial hypercholesterolemia. Arterioscler Thromb Vasc Biol 2002;22:817-23.
21. Mabuchi H, Koizumi J, Shimizu M et al. Development of coronary heart disease in familial hypercholesterolemia. Circulation 1989;79:225-32.
22. Armitage P, Berry G, Matthews J. Statistical Methods in Medical Research: Blackwell Science Ltd, 2002.
23. Roncaglioni MC, Santoro L, D'Avanzo B et al. Role of family history in patients with myocardial infarction. An Italian case-control study. GISSI-EFRIM Investigators. Circulation 1992;85:2065-72.
24. National Cholesterol Education Program (NCEP). Second report of the expert panel on detection, evaluation and treatment of high blood cholesterol in adults (Adult Treatment Panel II). Circulation 1994;89:1329-445.
25. Kunnas TA, Holmberg-Marttila D, Karhunen PJ. Analysis of estrogen receptor dinucleotide polymorphism by capillary gel electrophoresis with a population genetic study in 180 Finns. Hum Hered 1999;49:142-5.
26. Fujimoto J, Hirose R, Ichigo S et al. DNA polymorphism in B-domain of the estrogen receptor-α among Japanese women. Steroids 1998;63:146-8.
27. Kos M, Reid G, Denger S et al. Minireview: genomic organization of the human ERα gene promoter region. Mol Endocrinol 2001;15:2057-63.
28. Grandien K. Determination of transcription start sites in the human estrogen receptor gene and identification of a novel, tissue-specific, estrogen receptor-mRNA isoform. Mol Cell Endocrinol 1996;116:207-12.
29. Grandien K, Backdahl M, Ljunggren O et al. Estrogen target tissue determines alternative promoter utilization of the human estrogen receptor gene in osteoblasts and tumor cell lines. Endocrinology 1995;136:2223-9.
30. Hodges YK, Richer JK, Horwitz KB et al. Variant estrogen and progesterone receptor messages in human vascular smooth muscle. Circulation 1999;99:2688-93.
31. Herrington DM, Howard TD, Brosnihan B et al. Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein. Circulation. 2002;105:1879-82.