-
1
-
-
0021112308
-
19 steroids by five highly purified and reconstituted rat hepatic cytochrome P450 isoenzymes
-
19 steroids by five highly purified and reconstituted rat hepatic cytochrome P450 isoenzymes J. Biol. Chem. 258:8839-8847.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 8839-8847
-
-
Alexander, W.W.1
Dene, E.R.2
Paul, E.T.3
Wayne, L.4
-
2
-
-
0014791820
-
Two-substrate kinetics of drug-metabolizing enzyme systems of hepatic microsomes
-
Alvares, A. P., and Mannering, G. J. 1970. Two-substrate kinetics of drug-metabolizing enzyme systems of hepatic microsomes. Mol. Pharmacol. 6:206-212.
-
(1970)
Mol. Pharmacol.
, vol.6
, pp. 206-212
-
-
Alvares, A.P.1
Mannering, G.J.2
-
3
-
-
0026668190
-
Selective inhibition of rat hepatic microsomal cytochrome P-450. I. Effect of the in vivo administration of cimetidine
-
Chang, T., Levine, M., Bandiera, S. M., and Bellward, G. D. 1992a. Selective inhibition of rat hepatic microsomal cytochrome P-450. I. Effect of the in vivo administration of cimetidine. J. Pharmacol. Exp. Ther. 260:1441-1449.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.260
, pp. 1441-1449
-
-
Chang, T.1
Levine, M.2
Bandiera, S.M.3
Bellward, G.D.4
-
4
-
-
0026719245
-
Selective inhibition of rat hepatic microsomal cytochrome P-450. II. Effect of the in vitro administration of cimetidine
-
Chang, T., Levine, M., and Bellward, G. D. 1992b. Selective inhibition of rat hepatic microsomal cytochrome P-450. II. Effect of the in vitro administration of cimetidine. J. Pharmacol. Exp. Ther. 260: 1450-1455.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.260
, pp. 1450-1455
-
-
Chang, T.1
Levine, M.2
Bellward, G.D.3
-
5
-
-
0033521107
-
Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with a noncovalent yet irreversible binding mechanism
-
Chen, J. W., Luo, Y. L., Hwang, M. J., Peng, F. C., and Ling, K. H. 1999. Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with a noncovalent yet irreversible binding mechanism. J. Biol. Chem. 274:34916-34923.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34916-34923
-
-
Chen, J.W.1
Luo, Y.L.2
Hwang, M.J.3
Peng, F.C.4
Ling, K.H.5
-
6
-
-
33644811612
-
A new and rapid colorimetric determination of acetylcholinesterase activity
-
Ellman, G. L., Courtney, K. D., Jr., Anders, V., Featherstone, R. M. 1961. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol. 7:88-95.
-
(1961)
Biochem. Pharmacol.
, vol.7
, pp. 88-95
-
-
Ellman, G.L.1
Courtney Jr., K.D.2
Anders, V.3
Featherstone, R.M.4
-
7
-
-
0028136389
-
Oxidation of R(+)- and S(-)-carvedilol by rat liver microsomes. Evidence for stereoselective oxidation and characterization of the cytochrome P450 isozymes involved
-
Fujiumaki, M. 1994. Oxidation of R(+)- and S(-)-carvedilol by rat liver microsomes. Evidence for stereoselective oxidation and characterization of the cytochrome P450 isozymes involved. Drug Metab. Dispos. 22:700-708.
-
(1994)
Drug Metab. Dispos.
, vol.22
, pp. 700-708
-
-
Fujiumaki, M.1
-
8
-
-
0027165452
-
In vitro metabolism of 1,3-dioxane, 1,3-oxathiolane, and 1,3-dithiane derivatives of theophylline: A structure-metabolism correlation study
-
Grosa, G., Rocco, F., Ceruti, M., Dosio, F., Brusa, P., and Biglino, G. 1993. In vitro metabolism of 1,3-dioxane, 1,3-oxathiolane, and 1,3-dithiane derivatives of theophylline: A structure-metabolism correlation study. Farmaco 48:677-690.
-
(1993)
Farmaco
, vol.48
, pp. 677-690
-
-
Grosa, G.1
Rocco, F.2
Ceruti, M.3
Dosio, F.4
Brusa, P.5
Biglino, G.6
-
9
-
-
0020028678
-
Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis
-
Guengerich, F. P., Wang, P., and Davidson, N. K. 1982. Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochemistry 21:1698-1706.
-
(1982)
Biochemistry
, vol.21
, pp. 1698-1706
-
-
Guengerich, F.P.1
Wang, P.2
Davidson, N.K.3
-
10
-
-
0025944787
-
Age-dependent expression of cytochrome P450s in rat liver
-
Imaoka, S., Fujita, S., and Funae, Y. 1991. Age-dependent expression of cytochrome P450s in rat liver. Biochim. Biophys. Acta 1097:187-192.
-
(1991)
Biochim. Biophys. Acta
, vol.1097
, pp. 187-192
-
-
Imaoka, S.1
Fujita, S.2
Funae, Y.3
-
11
-
-
0021812736
-
Age-related alteration in the activities of drug-metabolizing enzymes and contents of sex-specific forms of cytochrome P-450 in liver microsomes from male and female rats
-
Kamataki, T., Maeda, K., Shimada, M., Kitani, K., Nagai, T., and Kato, R. 1985. Age-related alteration in the activities of drug-metabolizing enzymes and contents of sex-specific forms of cytochrome P-450 in liver microsomes from male and female rats. J. Pharmacol. Exp. Ther. 233:222-228.
-
(1985)
J. Pharmacol. Exp. Ther.
, vol.233
, pp. 222-228
-
-
Kamataki, T.1
Maeda, K.2
Shimada, M.3
Kitani, K.4
Nagai, T.5
Kato, R.6
-
12
-
-
0026716863
-
Sex-specific cytochrome P450 as a cause of sex- and species-related differences in drug toxicity
-
Kato, R., and Yamazoe, Y. 1992. Sex-specific cytochrome P450 as a cause of sex- and species-related differences in drug toxicity. Toxicol. Lett. 64/65:661-667.
-
(1992)
Toxicol. Lett.
, vol.64-65
, pp. 661-667
-
-
Kato, R.1
Yamazoe, Y.2
-
13
-
-
0021923830
-
Disappearance of sex difference in rat liver drug metabolism in old age
-
Kitagawa, H., Fujita, S., Suzuki, T., and Kitani, K. 1985. Disappearance of sex difference in rat liver drug metabolism in old age. Biochem. Pharmacol. 34:579-581.
-
(1985)
Biochem. Pharmacol.
, vol.34
, pp. 579-581
-
-
Kitagawa, H.1
Fujita, S.2
Suzuki, T.3
Kitani, K.4
-
14
-
-
0025972040
-
Regulation of the expression of the sex-specific isoforms of cytochrome P-450 in rat liver
-
Kobliakov, V., Popova, N., and Rossi, L. 1991. Regulation of the expression of the sex-specific isoforms of cytochrome P-450 in rat liver. Eur. J. Biochem. 195:585-591.
-
(1991)
Eur. J. Biochem.
, vol.195
, pp. 585-591
-
-
Kobliakov, V.1
Popova, N.2
Rossi, L.3
-
17
-
-
0028593649
-
Territrem, tremorgenic mycotoxins isolated from Aspergillus terreus
-
Ling, K. H. 1994. Territrem, tremorgenic mycotoxins isolated from Aspergillus terreus. J. Toxicol. Toxin Rev. 13:243-252.
-
(1994)
J. Toxicol. Toxin Rev.
, vol.13
, pp. 243-252
-
-
Ling, K.H.1
-
18
-
-
0018769106
-
Territrem, tremorgenic mycotoxins of Aspergillus terreus
-
Ling, K. H., Yang, C. K., and Peng, F. T. 1979. Territrem, tremorgenic mycotoxins of Aspergillus terreus. Appl. Environ. Microbiol. 37:355-357.
-
(1979)
Appl. Environ. Microbiol.
, vol.37
, pp. 355-357
-
-
Ling, K.H.1
Yang, C.K.2
Peng, F.T.3
-
19
-
-
0021369730
-
Isolation, chemical structure, acute toxicity and some physicochemical properties of territrem C from Aspergillus terreus
-
Ling, K. H., Liou, H. H., Yang, C. M., and Yang, C. K. 1984. Isolation, chemical structure, acute toxicity and some physicochemical properties of territrem C from Aspergillus terreus. Appl. Environ. Microbiol. 47:98-100.
-
(1984)
Appl. Environ. Microbiol.
, vol.47
, pp. 98-100
-
-
Ling, K.H.1
Liou, H.H.2
Yang, C.M.3
Yang, C.K.4
-
21
-
-
71849104860
-
Protein determinations with Folin phenol reagent
-
Lowry, O H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. 1951 Protein determinations with Folin phenol reagent J. Biol. Chem. 193:265-275.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
22
-
-
12344300709
-
Metabolism and elimination of tremorgenic mycotoxin
-
eds. P. S. Steyn and R. Vleggarr. IUPAC 6th International Symposium on Mycotoxin and Phycotoxin. Pretoria, Amsterdam: Elsevier
-
Mantle, P. G. 1986. Metabolism and elimination of tremorgenic mycotoxin. In Mycotoxins and phycotoxins, eds. P. S. Steyn and R. Vleggarr, pp. 399-408, 1985. IUPAC 6th International Symposium on Mycotoxin and Phycotoxin. Pretoria, Amsterdam: Elsevier.
-
(1985)
Mycotoxins and Phycotoxins
, pp. 399-408
-
-
Mantle, P.G.1
-
23
-
-
0030800884
-
Structure and anti-acetylcholinesterase activity of 4α- (hydroxymethyl)-4α-demethylterritrem B
-
Peng, F. C. 1997. Structure and anti-acetylcholinesterase activity of 4α-(hydroxymethyl)-4α-demethylterritrem B. J. Nat. Prod. 60:842-843.
-
(1997)
J. Nat. Prod.
, vol.60
, pp. 842-843
-
-
Peng, F.C.1
-
24
-
-
0037184666
-
Metabolism of territrem A (TRA) in liver microsomes from male Wistar rats: (3) Cytochrome P-450 isoforms catalyzing TRA metabolism
-
Peng, F. C., and Lin Wu, S. W. 2002. Metabolism of territrem A (TRA) in liver microsomes from male Wistar rats: (3) Cytochrome P-450 isoforms catalyzing TRA metabolism. J. Toxicol. Environ. Health A 65:2163-2175.
-
(2002)
J. Toxicol. Environ. Health A
, vol.65
, pp. 2163-2175
-
-
Peng, F.C.1
Lin Wu, S.W.2
-
25
-
-
0035824382
-
Metabolism of TRA in liver microsomes from male Wistar rats: (1) Identification of metabolites and their metabolic pathway
-
Peng, F. C., Lin Wu, S. W., and Wang, B. L. 2001a. Metabolism of TRA in liver microsomes from male Wistar rats: (1) Identification of metabolites and their metabolic pathway. J. Toxicol. Environ. Health A 64:579-593.
-
(2001)
J. Toxicol. Environ. Health A
, vol.64
, pp. 579-593
-
-
Peng, F.C.1
Lin Wu, S.W.2
Wang, B.L.3
-
26
-
-
0035930429
-
Metabolism of TRA in liver microsomes from male Wistar rats: (2) Sex differences and regulation with gonadal hormones and phenobarbital
-
Peng, F. C., Lin Wu, S. W., and Lin, J. J. 2001b. Metabolism of TRA in liver microsomes from male Wistar rats: (2) Sex differences and regulation with gonadal hormones and phenobarbital. J. Toxicol. Environ. Health A 64:661-671.
-
(2001)
J. Toxicol. Environ. Health A
, vol.64
, pp. 661-671
-
-
Peng, F.C.1
Lin Wu, S.W.2
Lin, J.J.3
-
27
-
-
0024319135
-
Inhibition of oxidative drug metabolism by orphenadrine: In vitro and in vivo evidence for isoenzyme-specific complexation of cytochrome P-450 and inhibition kinetics
-
Reidy, G. F., Mehta, I., and Murray, M. 1989. Inhibition of oxidative drug metabolism by orphenadrine: In vitro and in vivo evidence for isoenzyme-specific complexation of cytochrome P-450 and inhibition kinetics. Mol. Pharmacol. 35:736-743.
-
(1989)
Mol. Pharmacol.
, vol.35
, pp. 736-743
-
-
Reidy, G.F.1
Mehta, I.2
Murray, M.3
-
28
-
-
0018583778
-
Interaction of cimetidine with liver microsomes
-
Rendic, S., Sunjic, V., Toso, R., and Kajfez, F. 1979. Interaction of cimetidine with liver microsomes. Xenobiotica 9:555-564.
-
(1979)
Xenobiotica
, vol.9
, pp. 555-564
-
-
Rendic, S.1
Sunjic, V.2
Toso, R.3
Kajfez, F.4
-
29
-
-
0025164882
-
Developmental regulation of hepatic testosterone hydroxylases: Simultaneous activation and repression of constitutively expressed cytochromes P450 in senescent rats
-
Robinson, R. C., Nagata, K., Gelboin, H. V., Rifkind, J., Gonzalez, F. J., and Friedman, F. K. 1990. Developmental regulation of hepatic testosterone hydroxylases: Simultaneous activation and repression of constitutively expressed cytochromes P450 in senescent rats. Arch. Biochem. Biophys. 277:42-46.
-
(1990)
Arch. Biochem. Biophys.
, vol.277
, pp. 42-46
-
-
Robinson, R.C.1
Nagata, K.2
Gelboin, H.V.3
Rifkind, J.4
Gonzalez, F.J.5
Friedman, F.K.6
-
30
-
-
0025294782
-
Furafylline is a potent and selective inhibitor of cytochrome P4501A2 in man
-
Sesardic, D., Boobis, A. R., Murray, B. P., Murrat, S., Segura, J., De La Torre, R., and Davies, D. S. 1990. Furafylline is a potent and selective inhibitor of cytochrome P4501A2 in man. Br. J. Clin. Pharmacol. 29:651-663.
-
(1990)
Br. J. Clin. Pharmacol.
, vol.29
, pp. 651-663
-
-
Sesardic, D.1
Boobis, A.R.2
Murray, B.P.3
Murrat, S.4
Segura, J.5
De La Torre, R.6
Davies, D.S.7
-
31
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
-
Towbin, H., Staehelin, T., and Gordon, J. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Nat. Acad. Sci. USA 76:4350-4354.
-
(1979)
Proc. Nat. Acad. Sci. USA
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
32
-
-
0032863787
-
Role of CYP3A in bromperidol metabolism in rat in vitro and in vivo
-
Watanabe, M., Tateishi, T., Tanaka, M., Kumai, T., and Kobayashi, S. 1999. Role of CYP3A in bromperidol metabolism in rat in vitro and in vivo. Xenobiotica 29:839-846.
-
(1999)
Xenobiotica
, vol.29
, pp. 839-846
-
-
Watanabe, M.1
Tateishi, T.2
Tanaka, M.3
Kumai, T.4
Kobayashi, S.5
-
33
-
-
0021947032
-
Regulation of rat hepatic cytochrome P450: Age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes
-
Waxman, D. J., Dannan, G. A., and Guengerich, F. P. 1985. Regulation of rat hepatic cytochrome P450: Age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes. Biochemistry 24:4409-4417.
-
(1985)
Biochemistry
, vol.24
, pp. 4409-4417
-
-
Waxman, D.J.1
Dannan, G.A.2
Guengerich, F.P.3
|