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Volumn 17, Issue 4, 1996, Pages 865-871

Carcinogenicity, DNA adduct formation and K-ras activation by 7H-dibenzo[c,g]carbazole in strain A/J mouse lung

Author keywords

[No Author keywords available]

Indexed keywords

CARBAZOLE DERIVATIVE;

EID: 0029944407     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.4.865     Document Type: Article
Times cited : (27)

References (54)
  • 1
    • 15844388453 scopus 로고
    • IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, IARC, Lyon, France
    • International Agency for Research on Cancer (1983) Polynuclear Aromatic Compounds, Part I. IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, IARC, Lyon, France, vol. 2.
    • (1983) Polynuclear Aromatic Compounds, Part I , vol.2
  • 2
    • 0027075963 scopus 로고
    • Environmental sources. carcinogenicity, mutagenicity, metabolism and DNA binding of nitrogen and sulfur heterocyclic aromatics
    • Warshawsky,D. (1992) Environmental sources. carcinogenicity, mutagenicity, metabolism and DNA binding of nitrogen and sulfur heterocyclic aromatics. Environ. Carcinogen. Ecotox. Rev., 10, 1-71.
    • (1992) Environ. Carcinogen. Ecotox. Rev. , vol.10 , pp. 1-71
    • Warshawsky, D.1
  • 3
    • 0018998825 scopus 로고
    • Polycyclic organic matter (POM) and trace element contents of carbon black vent gas
    • Serth,R W and Hughes,T.W. (1980) Polycyclic organic matter (POM) and trace element contents of carbon black vent gas. Environ. Sci Technol., 14, 298-301.
    • (1980) Environ. Sci Technol. , vol.14 , pp. 298-301
    • Serth, R.W.1    Hughes, T.W.2
  • 4
    • 0002512236 scopus 로고
    • The carcinogenic nitrogen heterocycles in cigarette smoke condensates
    • Van Duuren,B.L., Bilbao,J.A. and Joseph,G.A. (1960) The carcinogenic nitrogen heterocycles in cigarette smoke condensates. J. Natl Cancer Inst., 25, 53-61.
    • (1960) J. Natl Cancer Inst. , vol.25 , pp. 53-61
    • Van Duuren, B.L.1    Bilbao, J.A.2    Joseph, G.A.3
  • 6
    • 0008228011 scopus 로고
    • The influence of methylation on carcinogenic activity I N-Methyl-3,4,5,6-dibenzcarbazole
    • Kirhy,A.H.M. and Peacock,P R. (1946) The influence of methylation on carcinogenic activity I N-Methyl-3,4,5,6-dibenzcarbazole. Br. J. Exp. Pathol., 27, 179-189.
    • (1946) Br. J. Exp. Pathol. , vol.27 , pp. 179-189
    • Kirhy, A.H.M.1    Peacock, P.R.2
  • 7
    • 0343694924 scopus 로고
    • Hepatic changes and subcutaneous and pulmonary tumors induced by subcutaneous injection of 3,4,5,6-dibenzcarbazole
    • Andervont,H.B. and Edwards,J.E. (1941) Hepatic changes and subcutaneous and pulmonary tumors induced by subcutaneous injection of 3,4,5,6-dibenzcarbazole. J. Natl Cancer Inst., 2, 139-149.
    • (1941) J. Natl Cancer Inst. , vol.2 , pp. 139-149
    • Andervont, H.B.1    Edwards, J.E.2
  • 8
    • 0002772636 scopus 로고
    • Squamous carcinoma of the forestomach and other lesions in mice following oral administration of 3,4,5,6-dibenzcarbazole
    • Armstrong,E.C. and Bonser,G.M. (1950) Squamous carcinoma of the forestomach and other lesions in mice following oral administration of 3,4,5,6-dibenzcarbazole. Br. J. Cancer. 4, 203-211.
    • (1950) Br. J. Cancer , vol.4 , pp. 203-211
    • Armstrong, E.C.1    Bonser, G.M.2
  • 9
    • 84921178545 scopus 로고
    • Biologic testing of carcinogens. II. Pulmonary tumor induction technique
    • Andervont,H.B. and Shimkin,M.B (1940) Biologic testing of carcinogens. II. Pulmonary tumor induction technique J. Natl Cancer Inst., 1, 225-239.
    • (1940) J. Natl Cancer Inst. , vol.1 , pp. 225-239
    • Andervont, H.B.1    Shimkin, M.B.2
  • 10
    • 0008187546 scopus 로고
    • The carcinogenic action of dibenzcarbazole
    • Boyland,G. and Brues,A M. (1937) The carcinogenic action of dibenzcarbazole. Proc. R. Soc Ser. B. 122, 429-441.
    • (1937) Proc. R. Soc Ser. B , vol.122 , pp. 429-441
    • Boyland, G.1    Brues, A.M.2
  • 11
    • 0015357321 scopus 로고
    • Carcinogenicity of 7H-dibenzo(c.g)carbazole in the respiratory tract of hamsters
    • Sellakumar,A. and Shubik,P (1972) Carcinogenicity of 7H-dibenzo(c.g)carbazole in the respiratory tract of hamsters. J Natl Cancer Inst., 48, 1641-1646.
    • (1972) J Natl Cancer Inst. , vol.48 , pp. 1641-1646
    • Sellakumar, A.1    Shubik, P.2
  • 12
    • 0008228012 scopus 로고
    • Induction of epithelial neoplasms in the urinary bladder of the dog by intravesical injection of a chemical carcinogen
    • Bonser,G.M., Crabbe,J.G.S and Jull,J.W. (1954) Induction of epithelial neoplasms in the urinary bladder of the dog by intravesical injection of a chemical carcinogen. J. Pathol. Bacteriol., 68, 561-564.
    • (1954) J. Pathol. Bacteriol. , vol.68 , pp. 561-564
    • Bonser, G.M.1    Crabbe, J.G.S.2    Jull, J.W.3
  • 13
    • 9244222327 scopus 로고
    • Induction of tumors by 3,4,5,6-dibenzcarbazole in male mice of CBA strain, which develops spontaneous hepatoma
    • Strong,L.C., Smith,G M. and Gardner,W.J. (1938) Induction of tumors by 3,4,5,6-dibenzcarbazole in male mice of CBA strain, which develops spontaneous hepatoma. Yale J. Biol Med., 10, 335-346.
    • (1938) Yale J. Biol Med. , vol.10 , pp. 335-346
    • Strong, L.C.1    Smith, G.M.2    Gardner, W.J.3
  • 14
    • 0028130699 scopus 로고
    • Carcinogenicity of 7H-dibenzo(c,g)carbazole, dibenz(a,j)acridine and benzo(a)pyrene in mouse skin and liver following topical application
    • Warshawsky,D., Barkley,W., Miller,M.L., LaDow,K. and Andringa,A. (1994) Carcinogenicity of 7H-dibenzo(c,g)carbazole, dibenz(a,j)acridine and benzo(a)pyrene in mouse skin and liver following topical application. Toxicology, 9, 135-149
    • (1994) Toxicology , vol.9 , pp. 135-149
    • Warshawsky, D.1    Barkley, W.2    Miller, M.L.3    LaDow, K.4    Andringa, A.5
  • 15
    • 0025968509 scopus 로고
    • Lung tumors in strain a mice as a bioassay for carcinogenicity of environmental chemicals
    • Stoner,G.D. (1991) Lung tumors in strain A mice as a bioassay for carcinogenicity of environmental chemicals. Exp. Lung Res., 17, 405-423.
    • (1991) Exp. Lung Res. , vol.17 , pp. 405-423
    • Stoner, G.D.1
  • 16
    • 0023639498 scopus 로고
    • Comparative carcinogenic potencies of 7H-dibenzo(c.g)carbazole. dibenz(a.j)acridine and benzo(a)pyrene in mouse skin
    • Warshawsky,D. and Barkley,W. (1987) Comparative carcinogenic potencies of 7H-dibenzo(c.g)carbazole. dibenz(a.j)acridine and benzo(a)pyrene in mouse skin. Cancer Lett., 37, 337-344.
    • (1987) Cancer Lett. , vol.37 , pp. 337-344
    • Warshawsky, D.1    Barkley, W.2
  • 17
    • 0026588984 scopus 로고
    • Comparative tumor-initiating ability of 7H-dibenzo(c,g)carbazole and dibenz(a.j)acridine in mouse skin
    • Warshawsky,D., Barkley,W., Miller,M.L., LaDow,K. and Andringa,A. (1992) Comparative tumor-initiating ability of 7H-dibenzo(c,g)carbazole and dibenz(a.j)acridine in mouse skin. Toxicology, 7, 233-243.
    • (1992) Toxicology , vol.7 , pp. 233-243
    • Warshawsky, D.1    Barkley, W.2    Miller, M.L.3    LaDow, K.4    Andringa, A.5
  • 18
    • 0022760675 scopus 로고
    • Dibenz[a.j]acridine metabolism: Identification of in vitro products formed by liver microsomes from 3-methylcholanthrene pretreated rats
    • Gill,J.H., Duke,C.C., Rosario,C.A., Ryan,A.J. and Holder,J.M. (1986) Dibenz[a.j]acridine metabolism: identification of in vitro products formed by liver microsomes from 3-methylcholanthrene pretreated rats. Carcinogenesis. 7, 1371-1378.
    • (1986) Carcinogenesis , vol.7 , pp. 1371-1378
    • Gill, J.H.1    Duke, C.C.2    Rosario, C.A.3    Ryan, A.J.4    Holder, J.M.5
  • 19
    • 0026569567 scopus 로고
    • Comparative metabolism of 7H-dibenzo(c,g)carbazole and dibenz (a.j)acridine by rat and mouse liver microsomes
    • Wan,L., Xue,W., Retlman,R., Radike,M. and Warshawsky,D. (1992) Comparative metabolism of 7H-dibenzo(c,g)carbazole and dibenz (a.j)acridine by rat and mouse liver microsomes. Chemico-Biol. Interact., 81, 131-147.
    • (1992) Chemico-Biol. Interact. , vol.81 , pp. 131-147
    • Wan, L.1    Xue, W.2    Retlman, R.3    Radike, M.4    Warshawsky, D.5
  • 20
    • 0019514166 scopus 로고
    • Heterocyclic polycyclic aromatic hydrocarbon carcinogenesis: 7H-dibenzo-(c,g)carbazole metabolism by microsomal enzymes from mouse and rat liver
    • Perin,F., Dufour,M., Mispelter,J., Ekert,B., Kunneke,C., Oesch,F. and Zajdela,F (1981) Heterocyclic polycyclic aromatic hydrocarbon carcinogenesis: 7H-dibenzo-(c,g)carbazole metabolism by microsomal enzymes from mouse and rat liver. Chemico-Biol. Interact., 35, 267-284.
    • (1981) Chemico-Biol. Interact. , vol.35 , pp. 267-284
    • Perin, F.1    Dufour, M.2    Mispelter, J.3    Ekert, B.4    Kunneke, C.5    Oesch, F.6    Zajdela, F.7
  • 21
    • 0023160682 scopus 로고
    • 32P-Postlabeling analysis of DNA adduction in mice by synthetic metabolites of the environmental carcinogen. 7H-dibenzo[c,g]carbazok: Chromatographic evidence for 3-hydro.xy-7H-dibenzo[c,g]carbazole being a proximate genotoxicant in liver but not skin
    • 32P-Postlabeling analysis of DNA adduction in mice by synthetic metabolites of the environmental carcinogen. 7H-dibenzo[c,g]carbazok: Chromatographic evidence for 3-hydro.xy-7H-dibenzo[c,g]carbazole being a proximate genotoxicant in liver but not skin. Carcinogenesis, 8, 591-597.
    • (1987) Carcinogenesis , vol.8 , pp. 591-597
    • Schurdak, M.E.1    Stong, D.B.2    Warshawsky, D.3    Randerath, K.4
  • 22
    • 0028213979 scopus 로고
    • Tissue distribution of DNA adducts of 7H-dibenzo(c,g)carbazole in mice following topical application of the parent compound and its major metabolites
    • Talaska,G., Reilman,R., Schamer,M., Roh,J.H., Xue,W. Fremont,S.L. and Warshawsky,D. (1994) Tissue distribution of DNA adducts of 7H-dibenzo(c,g)carbazole in mice following topical application of the parent compound and its major metabolites. Chem. Res. Toxicol., 7, 374-79.
    • (1994) Chem. Res. Toxicol. , vol.7 , pp. 374-379
    • Talaska, G.1    Reilman, R.2    Schamer, M.3    Roh, J.H.4    Xue, W.5    Fremont, S.L.6    Warshawsky, D.7
  • 23
    • 0024399045 scopus 로고
    • Binding of 7H-dibenzo [c,g]carbazole to polynucleotides and DNA in vitro
    • Lindquist,B. and Warshawsky,D (1989) Binding of 7H-dibenzo [c,g]carbazole to polynucleotides and DNA in vitro. Carcinogenesis, 10, 2187-95.
    • (1989) Carcinogenesis , vol.10 , pp. 2187-2195
    • Lindquist, B.1    Warshawsky, D.2
  • 25
    • 0024795892 scopus 로고
    • Ras oncogenes in chemical carcinogenesis
    • Sukumar,S. (1989) Ras oncogenes in chemical carcinogenesis. Curr. Topics Microbiol. Immunol., 148, 93-114.
    • (1989) Curr. Topics Microbiol. Immunol. , vol.148 , pp. 93-114
    • Sukumar, S.1
  • 26
    • 0007142725 scopus 로고
    • Activation of the K-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain a mouse
    • You,M., Candrian,U., Maronpot,R., Stoner,G. and Anderson,M. (1989) Activation of the K-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse. Proc. Natl Acad. Sci. USA, 86, 3070-3074.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 3070-3074
    • You, M.1    Candrian, U.2    Maronpot, R.3    Stoner, G.4    Anderson, M.5
  • 27
    • 0027517538 scopus 로고
    • Ki-ras oncogene mutations in tumors and DNA adducts formed by benz(j)aceanthrylene and benzo(a)pyrene in the lungs of strain A/J mice
    • Mass,M.J., Jeffers,A.J., Ross,J.A., Nelson,G., Galati,A.J., Stoner,G.D. and Nesnow,S. (1993) Ki-ras oncogene mutations in tumors and DNA adducts formed by benz(j)aceanthrylene and benzo(a)pyrene in the lungs of strain A/J mice. Mol. Carcinogen., 8, 186-192.
    • (1993) Mol. Carcinogen. , vol.8 , pp. 186-192
    • Mass, M.J.1    Jeffers, A.J.2    Ross, J.A.3    Nelson, G.4    Galati, A.J.5    Stoner, G.D.6    Nesnow, S.7
  • 28
    • 0028209227 scopus 로고
    • Cyclopenta[c.d]pyrene-induced tumorigenicity. Ki-ras codon 12 mutations and DNA adducts in strain A/J mouse lung
    • Nesnow,S., Ross,J.A., Nelson,G. et al. (1994) Cyclopenta[c.d]pyrene-induced tumorigenicity. Ki-ras codon 12 mutations and DNA adducts in strain A/J mouse lung. Carcinogenesis, 15, 601-606.
    • (1994) Carcinogenesis , vol.15 , pp. 601-606
    • Nesnow, S.1    Ross, J.A.2    Nelson, G.3
  • 30
    • 0018371589 scopus 로고
    • 32P]cGMP, and their use in the assay of adenylate and guanylate cyclases and cyclic nucleotide phosphodiesterases
    • 32P]cGMP, and their use in the assay of adenylate and guanylate cyclases and cyclic nucleotide phosphodiesterases Adv. Cyclic Nucleotide Res., 10, 135-167.
    • (1979) Adv. Cyclic Nucleotide Res. , vol.10 , pp. 135-167
    • Johnson, R.A.1    Walseth, T.F.2
  • 31
    • 33947454259 scopus 로고
    • Carcinogenic derivatives of carbazole. I. The synthesis of 1,2,7,8-, 1,2,5,6-dibenzocarbazole and some of their derivatives
    • Buu-Hoi,N.P., Hoan,N. and Khoi,N.H. (1949) Carcinogenic derivatives of carbazole. I. The synthesis of 1,2,7,8-, 1,2,5,6-dibenzocarbazole and some of their derivatives J. Org. Chem., 14, 492-497.
    • (1949) J. Org. Chem. , vol.14 , pp. 492-497
    • Buu-Hoi, N.P.1    Hoan, N.2    Khoi, N.H.3
  • 32
    • 0000530035 scopus 로고
    • Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo
    • Gupta,R.C. (1984) Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo. Proc. Natl Acad. Sci. USA. 81, 6943-6947.
    • (1984) Proc. Natl Acad. Sci. USA , vol.81 , pp. 6943-6947
    • Gupta, R.C.1
  • 33
    • 0023639585 scopus 로고
    • The correlation between DNA adducts and chromosomal aberrations in the target organ of benzidine-exposed, partially hepatectomized mice
    • Talaska,G., Au,W.W., Ward,J.B.,Jr. Randerath,K and Legator,M.S. (1987) The correlation between DNA adducts and chromosomal aberrations in the target organ of benzidine-exposed, partially hepatectomized mice. Carcinogenesis. 8, 1899-1905.
    • (1987) Carcinogenesis , vol.8 , pp. 1899-1905
    • Talaska, G.1    Au, W.W.2    Ward Jr., J.B.3    Randerath, K.4    Legator, M.S.5
  • 34
    • 0027121765 scopus 로고
    • 32P-Postlabelling and mass spectrometric methods for analysis of bulky, polyaromatic carcinogen-DNA adducts in humans
    • 32P-Postlabelling and mass spectrometric methods for analysis of bulky, polyaromatic carcinogen-DNA adducts in humans J Chromatogr., 580, 293-323.
    • (1992) J Chromatogr. , vol.580 , pp. 293-323
    • Talaska, G.1    Roh, J.H.2    Getek, T.3
  • 35
    • 0020334611 scopus 로고
    • 32P-Postlabelling analysis of non-radioactive aromatic carcinogen-DNA adducts
    • 32P-Postlabelling analysis of non-radioactive aromatic carcinogen-DNA adducts. Carcinogenesis. 3, 1081-1092.
    • (1982) Carcinogenesis , vol.3 , pp. 1081-1092
    • Gupta, R.C.1    Reddy, M.V.2    Randerath, K.3
  • 37
    • 0025228947 scopus 로고
    • 32P]postlabelling and subsequent thin-layer and high-pressure liquid chromatography
    • 32P]postlabelling and subsequent thin-layer and high-pressure liquid chromatography. Carcinogenesis, 11, 639-646.
    • (1990) Carcinogenesis , vol.11 , pp. 639-646
    • Talaska, G.1    Dooley, K.B.2    Kadlubar, F.F.3
  • 38
    • 0022267033 scopus 로고
    • Polycyclic aromatic hydrocarbon-DNA adducts: Formation, detection and characterization
    • Harvey,R. (ed.), American Chemical Society, Washington, DC
    • Jeffrey,A. (1985) Polycyclic aromatic hydrocarbon-DNA adducts: formation, detection and characterization. In Harvey,R. (ed.), Polycyclic Hydrocarbons and Carcinogenesis. American Chemical Society, Washington, DC. pp. 187-208.
    • (1985) Polycyclic Hydrocarbons and Carcinogenesis , pp. 187-208
    • Jeffrey, A.1
  • 39
    • 0023850178 scopus 로고
    • Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase
    • Saiki,R., Gelfand,D., Stoffel,S., Higuchi,R., Horn,G., Mullis,K. and Erlich,H. (1988) Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science, 235 487-91.
    • (1988) Science , vol.235 , pp. 487-491
    • Saiki, R.1    Gelfand, D.2    Stoffel, S.3    Higuchi, R.4    Horn, G.5    Mullis, K.6    Erlich, H.7
  • 40
    • 0022065447 scopus 로고
    • Structure and expression of amplified cKi-ras gene sequences in Y1 mouse adrenal tumor cells
    • George,D., Scott,A., Trusko,S., Glick,B., Ford,E. and Dorney,D. (1985) Structure and expression of amplified cKi-ras gene sequences in Y1 mouse adrenal tumor cells. EMBO J., 4, 1199-1203.
    • (1985) EMBO J. , vol.4 , pp. 1199-1203
    • George, D.1    Scott, A.2    Trusko, S.3    Glick, B.4    Ford, E.5    Dorney, D.6
  • 41
    • 0024756969 scopus 로고
    • Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
    • Orita,M., Suzuki,Y., Sekiya,T. and Hayashi,K. (1989) Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics, 5, 874-879.
    • (1989) Genomics , vol.5 , pp. 874-879
    • Orita, M.1    Suzuki, Y.2    Sekiya, T.3    Hayashi, K.4
  • 42
    • 0024592908 scopus 로고
    • Molecular analysis of spontaneous mutations at the gpt locus in Chinese hamster ovary (AS52) cells
    • Tindall,K. and Stankowski,L. (1989) Molecular analysis of spontaneous mutations at the gpt locus in Chinese hamster ovary (AS52) cells. Mutat. Res , 220, 241-253.
    • (1989) Mutat. Res , vol.220 , pp. 241-253
    • Tindall, K.1    Stankowski, L.2
  • 44
    • 0027292743 scopus 로고
    • Dose-dependent ras mutation spectra in N-nitrosodiethylamine-induced mouse liver tumors
    • Chen,B., Liu,L., Castonguay,H., Maronpot,R.R., Anderson,M.W. and You,M. (1993) Dose-dependent ras mutation spectra in N-nitrosodiethylamine-induced mouse liver tumors. Carcinogenesis, 14, 1603-1608.
    • (1993) Carcinogenesis , vol.14 , pp. 1603-1608
    • Chen, B.1    Liu, L.2    Castonguay, H.3    Maronpot, R.R.4    Anderson, M.W.5    You, M.6
  • 45
    • 0027052264 scopus 로고
    • DNA adduct measurements and tumor incidence during chronic carcinogen exposure in animal models: Implications for DNA adduct-based human cancer risk assessment
    • Poirier,M.C. and Beland,F.A. (1992) DNA adduct measurements and tumor incidence during chronic carcinogen exposure in animal models: implications for DNA adduct-based human cancer risk assessment. Chem. Res. Toxicol., 5, 749-755.
    • (1992) Chem. Res. Toxicol. , vol.5 , pp. 749-755
    • Poirier, M.C.1    Beland, F.A.2
  • 46
    • 0022271651 scopus 로고
    • 32P-Postlabeling analysis of DNA adducts persisting for up to 42 weeks in the skin, epidermis and dermis of mice treated topically with 7,12-dimethylbenz[a]anthracene
    • 32P-Postlabeling analysis of DNA adducts persisting for up to 42 weeks in the skin, epidermis and dermis of mice treated topically with 7,12-dimethylbenz[a]anthracene. Carcinogenesis, 6, 1117-1126.
    • (1985) Carcinogenesis , vol.6 , pp. 1117-1126
    • Randerath, E.1    Agrawal, H.P.2    Weaver, J.A.3    Bordelon, C.B.4    Randerath, K.5
  • 47
    • 10244226807 scopus 로고
    • Activation of the ras protooncogene in rodent model systems: Implications for understanding mechanisms of carcinogenicity
    • Lilly Research Laboratories
    • Belinsky,S.A. and Anderson,M.W. (1990) Activation of the ras protooncogene in rodent model systems: implications for understanding mechanisms of carcinogenicity. In New Horizons in Molecular Toxicology. Lilly Research Laboratories, pp. 9-14.
    • (1990) New Horizons in Molecular Toxicology , pp. 9-14
    • Belinsky, S.A.1    Anderson, M.W.2
  • 49
    • 0011493380 scopus 로고
    • Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons
    • Bizub,D., Wood,A.W. and Skalka,A.M. (1986) Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons. Proc. Natl Acad. Sci. USA, 83, 6048-6052.
    • (1986) Proc. Natl Acad. Sci. USA , vol.83 , pp. 6048-6052
    • Bizub, D.1    Wood, A.W.2    Skalka, A.M.3
  • 50
    • 0026425585 scopus 로고
    • Chemical and physical Carcinogenesis: Advances and perspectives for the 1990s
    • Hams,C.C. (1991) Chemical and physical Carcinogenesis: advances and perspectives for the 1990s. Cancer Res., 51 (suppl.). 5023-5044.
    • (1991) Cancer Res. , vol.51 , Issue.SUPPL. , pp. 5023-5044
    • Hams, C.C.1
  • 51
    • 0026658105 scopus 로고
    • Analysis of point mutations in murine c-Ha-ras of skin tumors initiated with dibenz(a,j)anthracene and derivatives
    • Gill,R.D., Beltran,L., Nettikumara,A.N., Harvey,R.G., Kootstra,A. and DiGiovanni,J. (1992) Analysis of point mutations in murine c-Ha-ras of skin tumors initiated with dibenz(a,j)anthracene and derivatives. Mol. Carcinogen., 6, 53-59.
    • (1992) Mol. Carcinogen. , vol.6 , pp. 53-59
    • Gill, R.D.1    Beltran, L.2    Nettikumara, A.N.3    Harvey, R.G.4    Kootstra, A.5    DiGiovanni, J.6
  • 54
    • 0027944536 scopus 로고
    • Tumor multiplicity, DNA adducts and K-ras mutation pattern of 5-methylchrysene in strain A/J mouse lung
    • You,L., Wang,D., Galati,A.J. et al. (1994) Tumor multiplicity, DNA adducts and K-ras mutation pattern of 5-methylchrysene in strain A/J mouse lung. Carcinogenesis, 15, 2613-2618.
    • (1994) Carcinogenesis , vol.15 , pp. 2613-2618
    • You, L.1    Wang, D.2    Galati, A.J.3


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