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Volumn 32, Issue 4, 2004, Pages 425-430

In vitro methods in the prediction of kinetics of drugs: Focus on drug metabolism

Author keywords

CYP; Cytochrome P450; Drug metabolism

Indexed keywords

CYTOCHROME P450;

EID: 12344308043     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290403200415     Document Type: Conference Paper
Times cited : (14)

References (14)
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    • Lipinski, C.A. (2003). Chris Lipinski discusses life and chemistry after the Rule of Five. Drug Discovery Today 8, 12-16.
    • (2003) Drug Discovery Today , vol.8 , pp. 12-16
    • Lipinski, C.A.1
  • 2
    • 0035313896 scopus 로고    scopus 로고
    • Screening for human ADME/Tox drug properties in drug discovery
    • Li, A.P. (2001). Screening for human ADME/Tox drug properties in drug discovery. Drug Discovery Today 6, 357-366.
    • (2001) Drug Discovery Today , vol.6 , pp. 357-366
    • Li, A.P.1
  • 3
    • 0035524043 scopus 로고    scopus 로고
    • In vitro prediction of gastrointestinal absorption and bioavailability: An experts' meeting report
    • Pelkonen, O., Boobis, A.R. & Gundert-Remy, U. (2001). In vitro prediction of gastrointestinal absorption and bioavailability: an experts' meeting report. European Journal of Clinical Pharmacology 57, 621-629.
    • (2001) European Journal of Clinical Pharmacology , vol.57 , pp. 621-629
    • Pelkonen, O.1    Boobis, A.R.2    Gundert-Remy, U.3
  • 6
    • 0346992330 scopus 로고    scopus 로고
    • Progress towards prediction of human pharmacokinetic parameters from in vitro technologies
    • Houston, J.B. & Galetin, A. (2003). Progress towards prediction of human pharmacokinetic parameters from in vitro technologies. Drug Metabolism Reviews 35, 393-415.
    • (2003) Drug Metabolism Reviews , vol.35 , pp. 393-415
    • Houston, J.B.1    Galetin, A.2
  • 8
    • 12344309738 scopus 로고    scopus 로고
    • Nuclear receptors CAR and PXR in metabolism and elimination of drugs
    • Honkakoski, P. (2003). Nuclear receptors CAR and PXR in metabolism and elimination of drugs. Current Pharmacogenomics 1, 75-85.
    • (2003) Current Pharmacogenomics , vol.1 , pp. 75-85
    • Honkakoski, P.1
  • 10
    • 0036606241 scopus 로고    scopus 로고
    • Predicting ADME properties in silica: Methods and models
    • Butina, D., Segall, M.D. & Frankcombe, K. (2002). Predicting ADME properties in silica: methods and models. Drug Discovery Today 7, Suppl. 11, S83-S88.
    • (2002) Drug Discovery Today , vol.7 , Issue.SUPPL. 11
    • Butina, D.1    Segall, M.D.2    Frankcombe, K.3
  • 11
    • 0037082199 scopus 로고    scopus 로고
    • The emerging importance of predicitive ADME simulation in drug discovery
    • Beresford, A.P., Selick, H.E. & Tarbit, M.H. (2002). The emerging importance of predicitive ADME simulation in drug discovery. Drug Discovery Today 7, 109-116.
    • (2002) Drug Discovery Today , vol.7 , pp. 109-116
    • Beresford, A.P.1    Selick, H.E.2    Tarbit, M.H.3
  • 12
    • 0042330313 scopus 로고    scopus 로고
    • ADME-Tox in drug discovery: Integration of experimented and computational technologies
    • Yu, H. & Adedoyin, A. (2003). ADME-Tox in drug discovery: integration of experimented and computational technologies. Drug Discovery Today 8, 852-861.
    • (2003) Drug Discovery Today , vol.8 , pp. 852-861
    • Yu, H.1    Adedoyin, A.2
  • 14
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    • Computer systems for the prediction of toxicity: An update
    • Greene, N. (2002). Computer systems for the prediction of toxicity: an update. Advanced Drug Delivery Reviews 54, 417-431.
    • (2002) Advanced Drug Delivery Reviews , vol.54 , pp. 417-431
    • Greene, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.