Inhibition of the Endogenous Volume-regulated Anion Channel (VRAC) in HEK293 Cells by Acidic Di-Aryl-Ureas

Journal of Membrane Biology

Volumn 196, Issue 2, 2003, Pages 83-94

  Helix N ^a   Strobaek D ^a   Dahl, B H ^a   Christophersen, P ^a  

^a NEUROSEARCH A S   (Denmark)

Author keywords

Chloride channel blockers; Electrophysiology; HEK cells; Patch clamp; Swelling; Volume; VRAC

Indexed keywords

2 [3 (3 TRIFLUOROMETHYLPHENYL)UREIDO]BENZOIC ACID; 4,4 DIISOTHIOCYANATOSTILBENE 2,2 DISULFONIC ACID; 5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; ANION CHANNEL; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; N [3,5 BIS(TRIFLUOROMETHYL)PHENYL] N' [4 BROMO 2 (1H TETRAZOL 5 YL)PHENYL]UREA; N [4 BROMO 2 (1H TETRAZOL 5 YL)PHENYL] N' (3 TRIFLUOROMETHYLPHENYL)UREA; N [4 BROMO 2 (1H TETRAZOL 5 YL)PHENYL] N' (4 NITROPHENYL)UREA; NS 1652; NS 3623; NS 3728; NS 3749; TAMOXIFEN; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ACIDITY; ARTICLE; CELL STRAIN; CELL SWELLING; CHANNEL GATING; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EMBRYO; EMBRYO CELL; ERYTHROCYTE MEMBRANE; ERYTHROCYTE VOLUME; HUMAN; HUMAN CELL; KIDNEY CELL; PATCH CLAMP; VOLUME REGULATED ANION CHANNEL;

BENZOIC ACIDS; CALCIUM CHANNEL BLOCKERS; CELL LINE; CELLS, CULTURED; CHLORIDE CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; HUMANS; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; KIDNEY; MEMBRANE POTENTIALS; PHENYLUREA COMPOUNDS; TETRAZOLES; UREA;

SIGMOIDEA;

EID: 0347364796     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-003-0627-x     Document Type: Article

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