A high throughput approach for simultaneous estimation of multiple synthetic trioxane derivatives using sample pooling for pharmacokinetic studies

Journal of Pharmaceutical and Biomedical Analysis

Volumn 37, Issue 1, 2005, Pages 127-133

  Singh, Rajendra Pratap ^a   Singh, S K ^a   Gupta, R C ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Antimalarial; Pharmacokinetics; Reversed phase liquid chromatography; Sample pooling; Serum

Indexed keywords

2 PROPANOL; ALKANE DERIVATIVE; ANTIMALARIAL AGENT; HEXANE; TRIOXANE DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG STABILITY; DRUG STORAGE; ELUTION; FEASIBILITY STUDY; FREEZE THAWING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; LINEAR SYSTEM; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REPRODUCIBILITY; STANDARD; STANDARDIZATION; ULTRAVIOLET SPECTROSCOPY; VALIDATION PROCESS;

ANIMALS; ARTEMISININS; CHEMISTRY, PHARMACEUTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG STABILITY; MALE; RATS; RATS, SPRAGUE-DAWLEY; SESQUITERPENES;

EID: 12344273389     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2004.09.038     Document Type: Article

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