Regional heterogeneity for the intracranial self-administration of ethanol and acetaldehyde within the ventral tegmental area of alcohol-preferring (P) rats: Involvement of dopamine and serotonin

Neuropsychopharmacology

Volumn 30, Issue 2, 2005, Pages 330-338

  Rodd, Zachary A ^a,b   Bell, Richard L ^a   Zharag, Ying ^a   Murphy, James M ^a   Goldstein, Avram ^c   Zaffaroni, Alejandro ^d   Li, Ting Kai ^e   McBride, William J ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY   (United States)

^d Technofyn Associates   (United States)

^e NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

Acetaldehyde reinforcement; Dopamine D2 receptor; Ethanol reinforcement; Intracranial self administration; Serotonin 3 receptor; Ventral tegmental area

Indexed keywords

ACETALDEHYDE; ALCOHOL; CATALASE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; QUINPIROLE; SEROTONIN; SEROTONIN 3 RECEPTOR; TRIAZOLE; TROPISETRON;

ALCOHOL CONSUMPTION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL HETEROGENEITY; DOPAMINERGIC NERVE CELL; DRINKING BEHAVIOR; DRUG DISCRIMINATION; DRUG PREFERENCE; DRUG SELF ADMINISTRATION; FEMALE; MESOLIMBIC DOPAMINERGIC SYSTEM; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; VENTRAL TEGMENTUM;

ACETALDEHYDE; ALCOHOL DRINKING; AMITROLE; ANIMALS; CATHETERIZATION; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CONDITIONING, OPERANT; DOPAMINE; DOPAMINE AGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ETHANOL; FEMALE; INDOLES; INJECTIONS; NEURONS; QUINPIROLE; RATS; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION; SEROTONIN; SEROTONIN ANTAGONISTS; STEREOTAXIC TECHNIQUES; VENTRAL TEGMENTAL AREA;

EID: 12344261654     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300561     Document Type: Article

References (43)

1. Aragon CMG, Amit Z (1992). The effect of 3-amino-1,2,4-triazole on voluntary ethanol consumption: evidence for brain catalase involvement in the mechanism of action. Neuropharmacology 31: 709-712.
2. Aragon CMG, Abitbol M, Amit Z (1986). Acetaldehyde may mediate reinforcement and aversion produced by ethanol. An examination using a conditioned taste-aversion paradigm. Neuropharmacology 25: 79-83.
3. 2 system. Biochem Pharmacol 44: 93-98.
4. Bozarth MA, Wise RA (1980). Electrolytic microinfusion transducer system: an alternative method of intracranial drug application. J Neurosci Methods 2: 273-275.
5. Bozarth MA, Wise RA (1981). Intracranial self-administration of morphine into the ventral tegmental area in rats. Life Sci 28: 551-555.
6. Brown ZW, Amit Z, Rockman GE (1979). Intraventricular self-administration of acetaldehyde, but not ethanol, in naive laboratory rats. Psychopharmacology 64: 271-276.
7. Campbell AD, Kohl RR, McBride WJ (1996). Serotonin-3 receptor and ethanol-stimulated somatodendritic dopamine release. Alcohol 13: 569-574.
8. Cohen G, Sinet PM, Heikkila R (1980). Ethanol oxidation by rat brain in vivo. Alcohol Clin Exp Res 4: 366-370.
9. Congar P, Bergevin A, Trudeau LE (2002). D2 receptors inhibit the secretory process downstream from calcium influx in dopaminergic neurons: implication of K+ channels. J Neurophysiol 87: 1046-1056.
10. Devine DP, Wise RA (1994). Self-administration of morphine, DAMGO, and DPDPE into the ventral tegmental area of rats. J Neurosci 14: 1978-1984.
11. Foddai M, Dosia G, Spiga S, Diana M (2004). Acetaldehyde increases dopaminergic neuronal activity in the VTA. Neuropsychopharmacology 29: 530-536.
12. Gatto GJ, McBride WJ, Murphy JM, Lumeng L, Li T-K (1994). Ethanol self-infusion into the ventral tegmental area by alcohol-preferring rats. Alcohol 11: 557-564.
13. Gill K, Menez JF, Lucas D, Deitrich RA (1992). Enzymatic production of acetaldehyde from ethanol in rat brain tissue. Alcohol Clin Exp Res 16: 910-915.
14. Hamby-Mason R, Chen JJ, Schenker S, Perez A, Henderson GI (1997). Catalase mediates acetaldehyde formation from ethanol in fetal and neonatal rat brain. Alcohol Clin Exp Res 21: 1063-1072.
15. Hunt WA (1996). Role of acetaldehyde in the actions of ethanol on the brain - A review. Alcohol 13: 147-151.
16. Ikemoto S, Glazier BS, Murphy JM, McBride WJ (1997a). Role of dopamine D-1 and D-2 receptors in the nucleus accumbens in mediating reward. J Neurosci 17: 8580-8585.
17. Ikemoto S, Murphy JM, McBride WJ (1997b). Self-infusion of GABA-A antagonists into the ventral tegmental area and adjacent regions. Behav Neurosci 111: 369-380.
18. Jeziorski M, White FJ (1989). Dopamine agonists at repeated 'autoreceptor-selective' doses: effects upon the sensitivity of A10 dopamine autoreceptors. Synapse 4: 267-280.
19. Klein RL, Sanna E, McQuilkin SJ, Whiting PJ, Harris RA (1994). Effects of 5-HT3 receptor antagonists on binding and function of mouse and human GABA-A receptors. Eur J Pharmacol 268: 237-246.
20. Koechling UM, Amit Z (1994). Effects of 3-amino-1,2,4-triazole on brain catalase in the mediation of ethanol consumption in mice. Alcohol 11: 235-239.
21. Kohl RR, Katner JS, Chernet E, McBride WJ (1998). Ethanol and negative feedback regulation of mesolimbic dopamine release in rats. Psychopharmacology 139: 79-85.
22. Koob GF, Roberts AJ, Schulteis G, Parsons LH, Heyser CJ, Hyytia P et al (1998). Neurocircuitry targets in ethanol: reward and dependence. Alcohol Clin Exp Res 22: 3-9.
23. Lovinger DM, White G (1991). Ethanol potentiation of 5-hydroxytryptamine- 3 receptor-mediated ion current in neuroblastoma cells and isolated adult mammalian neurons. Mol Pharmacol 40: 263-270.
24. Minabe Y, Ashby CR, Schwartz JE, Wang RY (1991). The 5-HT3 receptor antagonists LY277359 and granisetron potentiate the suppressant actions of apomorphine on the basal firing rate of ventral tegmental dopamine cells. Eur J Pharmacol 209: 143-150.
25. Murphy JM, Gatto GJ, Waller MB, McBride WJ, Lumeng L, Li T-K (1986). Effects of scheduled access on ethanol intake by the alcohol-preferring P line of rats. Alcohol 3: 331-336.
26. Paxinos G, Watson C (1986). The Rat Brain in Stereotaxk Coordinates. Academic Press: New York.
27. Rasmussen K, Stockton ME, Czachura JF (1991). The 5-HT3 receptor antagonist zatosetron decreases the number of spontaneously active AlO dopamine neurons. Eur J Pharmacol 205: 113-116.
28. Rodd ZA, Bell RL, Melendez RI, Kuc KA, Lumeng L, Li T-K et al (2004a). Comparison of intracranial self-administration of ethanol within the posterior ventral tegmental area between alcohol-preferring (P) and Wistar rats. Alcohol Clin Exp Res 28: 1212-1219.
29. Rodd ZA, Bell RL, Zhang Y, Goldstein A, Zaffaroni A, McBride WJ et al (2003). Salsolinol produces reinforcing effects in the nucleus accumbens shell of alcohol-preferring (P) rats. Alcohol Clin Exp Res 27: 440-449.
30. Rodd ZA, Melendez RI, Bell RL, Kuc KA, Zhang Y, Murphy JM et al (2004b). Intracranial self-administration of ethanol within the ventral tegmental area of male Wistar rats: evidence for regional heterogeneity and involvement of dopamine neurons. J Neurosci 24: 1050-1057.
31. Rodd-Henricks ZA, Bell RL, Kuc KA, Murphy JM, McBride WJ, Lumeng L et al (2001). Effects of concurrent access to multiple ethanol concentrations and repeated deprivations on alcohol intake of alcohol-preferring rats. Alcohol Clin Exp Res 25: 1140-1150.
32. Rodd-Henricks ZA, McKinzie DL, Crile RS, Murphy JM, McBride WJ (2000). Regional heterogeneity for the intracranial self-administration of ethanol within the ventral tegmental area of female Wistar rats. Psychopharmacology 149: 217-224.
33. Rodd-Henricks ZA, McKinzie DL, Li T-K, Murphy JM, McBride WJ (2002a). Cocaine is self-administered into the shell, but not the core, of the nucleus accumbens of Wistar rats. J Pharmacol Exp Ther 303: 1216-1226.
34. Rodd-Henricks ZA, McKinzie DL, Melendez RI, Berry N, Murphy JM, McBride WJ (2003). The effects of serotonin-3 receptor antagonists on the intracranial self-administration of ethanol into the posterior VTA of Wistar rats. Psychopharmacology 165: 252-259.
35. Rodd-Henricks ZA, Melendez RI, Zaffaroni A, Goldstein A, McBride WJ, Li T-K (2002b). The reinforcing effects of acetaldehyde in the posterior ventral tegmental area of alcohol-preferring rats. Pharmacol Biochem Behav 72: 55-64.
36. Sanchis-Segura C, Aragon CM (2002). Brain catalase inhibition blocks ethanol-related decrease of blood luteinizing hormone levels in mice. Alcohol Clin Exp Res 26: 1275-1280.
37. Sippel HW (1974). The acetaldehyde content in rat brain during ethanol metabolism. J Neurochem 23: 451-452.
38. Smith BR, Amit Z, Splawinsky J (1984). Conditioned place preference induced by intraventricular infusions of acetaldehyde. Alcohol 1: 193-195.
39. Smith BR, Aragon CM, Amit Z (1997). Catalase and the production of brain acetaldehyde: a possible mediator for the psychopharmacological effects of ethanol. Addict Biol 2: 277-289.
40. Sung KW, Engel SR, Allan AM, Lovinger DM (2000). 5-HT3 receptor function and potentiation by alcohols in frontal cortex neurons from transgenic mice overexpressing the receptor. Neuropharmacology 39: 2346-2351.
41. Waller MB, McBride WJ, Gatto GJ, Lumeng L, Li T-K (1984). Intragastric self-infusions of ethanol by the P and NP (alcohol-preferring and -non-preferring) lines of rats. Science 225: 78-80.
42. Zimatkin SM (1991). Histochemical study of aldehyde dehydrogenase in the rat CNS. J Neurochem 56: 1-11.
43. Zimatkin SM, Liopo AV, Deitrich RA (1998). Distribution and kinetics of ethanol metabolism in rat brain. Alcohol Clin Exp Res 22: 1623-1627.