Catalase mediates acetaldehyde formation from ethanol in fetal and neonatal rat brain

Alcoholism: Clinical and Experimental Research

Volumn 21, Issue 6, 1997, Pages 1063-1072

  Hamby Mason, Rhoda ^c   Chen, Juan Juan ^a   Schenker, Steven ^a   Perez, Antonio ^a   Henderson, George I ^a,b  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c NONE

Author keywords

Acetaldehyde; Brain; Catalase; Ethanol; Fetus

Indexed keywords

4 METHYLPYRAZOLE; ACETALDEHYDE; ALCOHOL; AMITROLE; CATALASE; CYTOCHROME P450 INHIBITOR; ENZYME INHIBITOR; SODIUM AZIDE;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; FEMALE; FETUS; IMMUNOHISTOCHEMISTRY; NEWBORN; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT;

ANIMALIA; FELIS CATUS;

EID: 0030885790     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1997.tb04255.x     Document Type: Article

References (72)

1. Committee on Substance Abuse and Committee on Children with Disabilities: Fetal alcohol syndrome and fetal alcohol effects. Pediatrics 91:1004-1006, 1943
2. Day NL, Robles N, Richardson G, Geva D, Taylor P, Scher M, Stoffer D, Cornelius M, Goldschmidt L: The effects of prenatal alcohol use on the growth of children at three years of age. Alcohol Clin Exp Res 15:67-71, 1991
3. West JR, Hamre KM, Pierce DR: Delay in brain development induced by alcohol in artificially reared rat pups. Alcohol 1:213-223, 1984
4. Diaz J, Samson HH: Impaired brain growth in neonatal rat pups exposed to ethanol. Science 208:751-753, 1980
5. Miller MW: Limited ethanol exposure selectively alters the proliferation of precursor cells in the cerebral cortex. Alcohol Clin Exp Res 20:139-143, 1996
6. Miller MW: Generation of neurons in the rat dentate gyrus and hippocampus: Effects of prenatal and postnatal treatment with ethanol. Alcohol Clin Exp Res 19:1500-1509, 1995
7. West JR, Goodlett CR, Bonthius DJ, Hamre KM, Marcussen BL: Cell population depletion associated with fetal alcohol brain damage: Mechanisms of BAC-dependent cell loss. Alcohol Clin Exp Res 14:813-818, 1990
8. Goodlett CR, Thomas JD, West JR: Long-term deficits in cerebellar growth and rotorod performance of rats following "binge-like" alcohol exposure during the neonatal brain growth spurt. Neurotoxicol Teratol 13:69-74, 1991
9. Phillips SC, Cragg BG: A change in susceptibility of rat cerebellar Purkinje cells to damage by alcohol during fetal, neonatal and adult life. Neuropathol Appl Neurobiol 8:441-454, 1982
10. Miller MW: Effect of pre- or postnatal exposure to ethanol on the total number of neurons in the principal sensory nucleus of the trigeminal nerve: Cell proliferation versus neuronal death. Alcohol Clin Exp Res 19:1359-1364, 1995
11. Streissguth AP, Barr HM, Sampson PD: Moderate prenatal alcohol exposure: Effects on child IQ and learning problems at age 71/2 years. Alcohol Clin Exp Res 14:662-669, 1990
12. Westcott JY, Weiner H, Schultz J, Myers RD: In vivo acetaldehydc in the brain of the rat treated with ethanol. Biochem Pharmacol 29:411-417, 1980
13. Clarke DW, Steenaart NAE, Slack CJ, Brien JF: Pharmacokinetics of ethanol and its metabolite, acetaldehyde, and fetotolethality in the third-trimester pregnant guinea pig for oral administration of acute, multiple-dose elhanol. Can J Pharmacol 64:1060-1067, 1986
14. Clarke DW, Steenaart NAE. Brien JF: Disposition of ethanol and activity of hepatic and placental alcohol dehydrogenase and aldehyde dehydrogenases in third-trimester pregnant guinea pig for single and short-term oral ethanol administration. Alcohol Clin Exp Res 10:330-336, 1986
15. Gill K, Menez JF, Lucas D, Deitrich RA: Enzymatic production of acetaldehyde from ethanol in rat brain tissue. Alcohol Clin Exp Res 16:910-915, 1992
16. Jennett RB, Tuma DJ, Sorrell MF: Effects of acetaldehyde on hepatic proteins. Prog Liver Dis 9:325-333, 1990
17. Lieber CS: Hepatic, metabolic and toxic effects of ethanol: 1991 update. Alcohol Clin Exp Res 15:573-592, 1991
18. Webster WS, Walsh DA, McEwen SE, Lipson AH: Some teratogenic properties of ethanol and acetaldehyde in C57BL/6J mice: Implications for the study of the fetal alcohol syndrome. Teratology 27:231-243, 1983
19. Campbell MA, Fantel AG: Teratogenicity of acetaldehyde in vitro: Relevance to the fetal alcohol syndrome. Life Sci 32:2641-2647, 1983
20. O'Shea KS, Kaufman MH: The teratogenic effect of acetaldehyde: Implications for the study of the fetal alcohol syndrome. J Anat 128:65-76, 1979
21. Karl PI, Gordon BHJ, Lieber CS, Fisher SE: Acetaldehyde production and transfer by the perfused human placental cotyledon. Science 242:273-275, 1988
22. Oshino N, Oshino R, Chance B: The characteristics of the peroxidatic reaction of catalase in ethanol oxidation. Biochem J 131:555-567, 1973
23. Anandatheerthavarada HP, Shanker SK, Bhamre S, Boyd MR, Song BJ, and Vijayalakshmi R. Induction of brain cytochrome P-450IIE1 by chronic ethanol treatment. Brain Res 601:279-285, 1993
24. Hunt WA: Role of acetaldelyde in the actions of ethanol on the brain-A review. Alcohol 13:147-151, 1996
25. Devi BG, Henderson GI, Frosto TA, Schenker S: Effect of ethanol on mitochondria morphologic and biochemical integrity of the fetal rat hepatocytes in culture. Hepatology 19:648-659, 1993
26. Devi BG, Henderson GI, Frosto TA, Schenker S: Effect of acute ethanol exposure on cultured fetal rat hepatocytes: Relation to mitochondrial function. Alcohol Clin Exp Res 18:1436-1442, 1994
27. Henderson GI, Devi BG, Perez A, Schenker S: In utero ethanol exposure elicits oxidative stress in the rat fetus. Alcohol Clin Exp Res 19:714-720, 1995
28. Devi BG, Schenker S, Mazloum B, Henderson GI: Ethanol-induced oxidative stress and enzymatic defenses in cultured fetal rat hepatocytes. Alcohol 13:327-332, 1996
29. Dobbing J, Sands J: Quantitative growth and development of the human brain. Arch Dis Child 48:757-767, 1973
30. Dobbing J, Sands J: Comparative aspects of the brain growth spurt. Early Hum Dev 3:79-83, 1979
31. Lucas D, Menez JF, Bertha F, Dennec Y, Floch HH: Determination of free acetaldehyde in blood as the dinitrophenylhydrazone derivative by high-performance liquid chromatography. J Chromatogr 382:57-66, 1986
32. Ung-Chhun NS, Collins MA: Estimation of blood acetaldehyde during ethanol metabolism: A sensitive HPLC/fluorescence micro assay with negligible artifactual interference. Alcohol 4:473-476, 1987
33. Eaton JW, Boraas M, Etkin ML: Catalase activity and red cell metabolism, in Brewer G (ed): Hemoglobin and Red Cell Structure and Function. New York, Plenum Publishing Co., 1972, p 121
34. Eriksson CJP, Sippel HW, Forsander OA: The determination of acetaldehyde in biological samples by head-space gas chromatography. Anal Biochem 80:116-124, 1977
35. Lindros KO, Eriksson CJP: Artifactual acetaldehyde formation during human blood perchlorate deproteinization. Subst Alcohol Act/Misuse 2:341-347, 1981
36. George MC, Lucas D, Ribiere C, et al: Desferrioxamine: A method to decrease the artifactual formation of acetaldehyde from ethanol in human blood samples. Adv Biosci 71:177-181, 1988
37. Eriksson CJP, Mizoi Y, Fukunaga T: The determination of acetaldehyde in human blood by the perchloric acid precipitation method: The characterization and elimination of artifactual acetaldehyde formation. Anal Biochem 125:259-263, 1982
38. Fukunaga T, Sillanaukee P, Eriksson CJP: Occurrence of blood acetaldehyde in women during ethanol intoxication: preliminary findings. Alcohol Clin Exp Res 17:1198-1200, 1993
39. Henderson GI, Schenkcr S: The effect of maternal alcohol consumption on the viability and visceral development of the newborn rat. Res Commun Chem Pathol Pharmacol 16:15-32, 1977
40. Henderson GI, Hoyumpa AM, McClain C, Schenker S: The effects of chronic and acute alcohol administration on fetal development in the rat. Alcohol Clin Exp Res 3:99-106, 1979
41. Fernandez K, Caul WF, Boyd JE, Henderson GI, Michallis RC: Malformations and growth of rat fetuses exposed to brief periods of alcohol in utero. Teratol Mutat Carcin 3:457-460, 1983
42. West JR, Hamre KM, Cassell MD: Effects of ethanol exposure during the third trimester equivalent on neuron number in rat hippocampus and dentate gyrus. Alcohol Clin Exp Res 10:190-197, 1986
43. Pierce DR, Goodlett CR, West JR: Differential neuronal loss following postnatal alcohol exposure. Teratology 40:113-126, 1989
44. Bonthius DJ, West JR: Alcohol-induced neuronal loss in developing rats: Increased brain damage with binge exposure. Alcohol Clin Exp Res 14:107-118, 1990
45. Bonthius DJ. West JR: Acute and long-term neuronal deficits in the rat olfactory bulb following alcohol exposure during the brain growth spurt. Neurotoxicol Teratol 13:611-619, 1991
46. Del Maestro R, McDonald W: Distribution of Superoxide dismutase, glutathione peroxidase and catalase in developing rat brain. Mech Age Dev 41:29-38, 1987
47. Keilin D, Nicholls P: Reactions of calalase with hydrogen peroxide and hydrogen donors. Biochem Biophys Acta 29:302-307, 1958
48. Boleda MD, Farres J, Guerri C, Pares X: Alcohol dehydrogenase isozymes in rat development. Effects of maternal ethanol consumption. Biochem Pharmacol 43:1555-1561, 1992
49. Danh HC, Benedict MS, Dostert P: Age-related changes in aldehyde dehydrogenase activities of rat brain, liver and heart. J Neurochem 41:618-622, 1983
50. Cohen G, Sinet PM, Heikkila RE: Ethanol oxidation by rat brain in vivo. Alcohol Clin Exp Res 4:366-370, 1980
51. Tampier L, Quintanilla ME, Letelier C, Mardones J: Effect of 3-amino-l,2,4-triazole on narcosis and time lethality of ethanol in UchA rats. Alcohol 5:5-8, 1988
52. 2 system. Biochem Pharmacol 44:93-98, 1992
53. Aspberg A, Soderback M, Tottmar O: Increase in catalase activity in developing rat brain reaggregation cultures in the presence of ethanol. Biochem Pharmacol 46:1873-1976, 1993
54. Montoliu C, Sancho-Tello M, Azorin I, Burgal M, Valles S, Renau-Piqueras J, Guerri C: Ethanol increases cytochrome P4502E1 and induces oxidative stress in astrocytes. J Neurochem 65:2561-2570, 1995
55. Yasmineh WG, Theologides A: Catalase as a roving scavenger of hydrogen peroxide: A hypothesis. J Lab Clin Med 122:110-114, 1993
56. Lock EA, Mitchell AM, Elcomhe CR: Biochemical mechanisms of induction of hepatic peroxisome proliferation. Ann Rev Pharmacol Toxicol 29:145-163, 1989
57. Issemann I, Green S: Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 347:645-650, 1990
58. Tsukamoto T, Miura S, Fujiki Y: Restoration by a 35K membrane protein of peroxisome assembly in a peroxisome-deficient mammalian cell mutant. Nature 350:77-81, 1991
59. Aspberg A, Tottmar O: Ethanol-induced increase in catalase activity in reaggregation cultures of rat brain cells is due to increased oligodendrocyte differentiation. Alcohol Clin Exp Res 18:620-624, 1994
60. Israel Y, MacDonald A, Niemcla O, Zamel D, Shami E, Zywulko M, Klajner F, Borgono C: Hypersensitivity to acetaldehyde-protein adducts. Mol Pharmacol 42:711-717
61. Lin RC, Zhou FC, Fillenwarlh MJ, Lumeng L: Zonal distribution of protein-acctaldehyde adducts in the liver of rats fed alcohol for long periods. Hepatology 18:864-869, 1993
62. Lin RC, Lumeng L: Formation of a protein-acetaldehyde adduct in liver during chronic ethanol exposure, in Witmer CM, et al (eds): Biolog- ical Reactive Intermediates IV. New York, Plenum Press, 1990, pp 139-149
63. 4-3-kelosteroid 5β-reduetase. Hepatology 23:115-122, 1996
64. Giavini E, Broccia ML, Prati M, Bellono D, Menegola E: Effects of ethanol and acetaldehyde on rat embryo developing in vitro. In Vitro Cell Dev Biol 28A:205-210, 1992
65. Heap L, Ward RJ, Abiaka C, Dexter D, Lawlor M, Pratt O, Thomson A, Shaw K, Peters TJ: The influence of brain acetaldehyde on oxidative status, dopamine metabolism and visual discrimination task. Biochem Pharmacol 50:263-270, 1995
66. Bradley DM, Paiva M, Tonjes LA, Heaton MB: In vitro comparison of the effects of ethanol and acetaldehyde on dorsal root ganglion neurons. Alcohol Clin Exp Res 19:1345-1350, 1995
67. Bergamaschi S, Govoni S, Ruis RA, Trabucchi M: Acute ethanol and acelaldehyde administration produce similar effects on L-type calcium channels in rat brain. Alcohol 5:337-340, 1988
68. Koechling UM, Amit Z: Effects of 3-amino-1,2,4-triazole on brain catalase in the mediation of ethanol consumption in mice. Alcohol 11: 235-239, 1994
69. Tampier L, Quintanilla ME, Mardones J: Effects of aminotriazole on ethanol, water, and food intake and on brain catalase in UChA and UChB rats. Alcohol 12:341-344. 1995
70. Maher JJ, Friedman SL: Pathogenesis of hepatic fibrosis, in Hall P (ed): Alcoholic Liver Disease. Pathology and Pathogenesis, ed 2. Boston, Edward Arnold, 1996, pp 71-88
71. Montoliu C, Valles S, Renau-Piqueres J, Guerri C: Ethanol-induced oxygen radical formation and lipid peroxidation in rat brain: Effect of chronic alcohol consumption. J Neurochem 63:1855-1862, 1994
72. Guerri C, Sanchis R: Acetaldehyde and alcohol levels in pregnant rats and their fetuses. Alcohol 2:267-270, 1985