Does nitric oxide allow endothelial cells to sense hypoxia and mediate hypoxic vasodilatation? In vivo and vitro studies

Journal of Physiology

Volumn 546, Issue 2, 2003, Pages 521-527

  Edmunds, Nicholas J ^a,c   Moncada, Salvador ^b   Marshall, Janice M ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC GMP; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE TRIPHOSPHATE; BRADYKININ; CYTOCHROME C OXIDASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; OXYGEN;

ANESTHESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ARTERIAL OXYGEN TENSION; ARTERY DILATATION; ATTENUATION; BINDING SITE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMORAL ARTERY FLOW; HINDLIMB; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; REVIEW; SENSOR; ARTICLE; CELL HYPOXIA; OXYGEN TENSION; PIG; THORACIC AORTA; VASCULAR RESISTANCE; VASODILATATION;

ADENOSINE; ANIMALS; ANOXIA; CYCLIC GMP; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HINDLIMB; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE DONORS; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P1; S-NITROSO-N-ACETYLPENICILLAMINE; VASODILATION; VASODILATOR AGENTS; XANTHINES;

EID: 12244252787     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2002.023663     Document Type: Review

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