Deciphering the mysteries of myoglobin in striated muscle

Acta Physiologica Scandinavica

Volumn 168, Issue 4, 2000, Pages 623-634

  Conley, Kevin E ^a   Ordway, G A ^b   Richardson, R S ^c  

^a UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Body size scaling; Facilitated diffusion; Magnetic resonance spectroscopy; Myoglobin knockout mouse; O2 diffusion; Oxidative phosphorylation

Indexed keywords

MYOGLOBIN; OXYGEN;

ANOXIA; CONFERENCE PAPER; DIVING; HUMAN; IN VIVO STUDY; KNOCKOUT MOUSE; MITOCHONDRION; MOUSE; MUSCLE CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATIVE PHOSPHORYLATION; OXYGEN AFFINITY; OXYGEN DIFFUSION; OXYGEN SATURATION; OXYGEN SUPPLY; PRIORITY JOURNAL; SKELETAL MUSCLE;

ANIMALS; HUMANS; MUSCLE, SKELETAL; MYOGLOBIN; OXYGEN CONSUMPTION;

EID: 0034038372     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.2000.00714.x     Document Type: Conference Paper

References (62)

1. 31P MRS ot soleus and gastrocnemius in Sherpes during graded calf muscle exercise. Am J Physiol 273, R999-R1007.
2. Andersen, P., Adams, R.P., Sjogaard, G., Thorbe, A. & Saltin, B. 1985. Dynamic knee extension as a model for study of isolated exercising muscle in humans. J Appl Physiol 59 (5), 1647-1653.
3. 2max and oxidative capacity in muscles of Standardbred horses. J Appl Physiol 73, 2274-2282.
4. Barstow, T., Buchthal, S., Zanconato, S. & Cooper, D. 1994. Changes in potential controllers of human skeletal muscle respiration during incremental calf exercise. J Appl Physiol 77, 2169-2176.
5. Bentley, T.B. & Pittman, R.N. 1997. Influence of temperature on oxygen diffusion in hamster retractor muscle. Am J Physiol 272, H1106-H1112.
6. Chance, B. & Quistorff, B. 1978. Study of tissue oxygen gradients by single and multiple indicators. Adv Exp Med Biol 94, 331-338.
7. Chemelli, R.M., Willie, J.T., Sinton, C.M. et al. 1999. Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation. Cell 98 (4), 437-451.
8. Conley, K.E. & Jones, C. 1996. Myoglobin content and oxygen diffusion: Model analysis of horse and steer muscle. Am J Physiol 271, C2027-C2036.
9. Conley, K.E., Kushmerick, M.J. & Jubrias, S.A. 1998. Glycolysis in independent of oxygenation state in stimulated human skeletal muscle in vivo. J Physiol 511 (3), 935-945.
10. Connett, R.J., Gayeski, T.E.J. & Honig, C.R. 1983. Lactate production in a pure red muscle in absence of anoxia: Mechanisms and significance. Adv Exp Med Biol 159, 327-335.
11. Connett, R.J., Gayeski, T.E.J. & Honig, C.R. 1984. Lactate accumulation in fully aerobic, working, dog gracilis muscle. Am J Physiol 246, H120-H128.
12. 2 in working red skeletal muscle in situ. J Appl Physiol 61, 402-408.
13. Doeller, J. & Wittenberg, B. 1990. Intracellular calcium and high-energy phophates in isolated cardiac myocytes. Am J Physiol 259, H1851-H1859.
14. 3 redox state. J Appl Physiol 75, 790-797.
15. Federspiel, W.J. & Popel, A.S. 1986. A theoretical analysis of the effect of the particluate nature of blood on oxygen release in capillaries. Microvasc Res 32, 164-189.
16. Garry, D.J., Ordway, G.A., Lorenz, J.N. et al. 1998. Mice without myoglobin. Nature 395 (6705), 905-908.
17. Godecke, A., Flogel, U., Zanger, K. et al. 1999. Disruption of myoglobin in mice induces multiple compensatory mechanisms. Proc Natl Acad Sci USA 96 (18), 10495-10500.
18. Gorzynski, R.J. & Duling, B.R. 1978. Role of oxygen in functional vasodilation in hamster striated muscle. Am J Physiol 235, H505-H515.
19. Hogan, M.C., Richardson, R.S. & Haseler, L. 1999. Human muscle performance and PCr hydrolysis with varied inspired oxygen fractions: A 31P-MRS study. J Appl Physiol 86, 1367-1374.
20. 2. Am J Physiol 265, H868-H875.
21. Honig, C.R., Odoroff, C.L. & Frieson, J.L. 1982. Active and passive control in red muscle at rest and in exercise. Am J Physiol 243, H196-H206.
22. Hoppeler, H., Mathieu, O., Krauer, R., Claassen, H., Armstrong, R. & Weibel, E.R. 1981. Design of the mammalian respiratory system. VI. Distribution of mitochondria and capillaries in various muscles. Respir Physiol 44, 87-111.
23. Hudlicka, O., Egginton, S. & Brown, M.D. 1988. Capillary diffusion distances-their importance for cardiac and skeletal muscle performance. NIPS 3, 134-138.
24. Jobsis, F.F. & Stainsby, W.N. 1968. Oxidation of NADH during contractions of circulated skeletal muscle. Respir Physiol 4, 292-300.
25. Jürgens, K.D., Peters, T. & Gros, G. 1994. Diffusivity of myoglobin in intact skeletal muscle cells. Proc Natl Acad Sci, USA 91, 3829-3833.
26. Katz, A. & Sahlin, K. 1988. Regulation of lactic acid production during exercise. J Appl Physiol 65, 509-518.
27. Kayar, S.R. & Weiss, H.R. 1992. Diffusion distances, total capillary length and mitochondrial volume in pressure-overloaded myocardial hypertrophy. J Mol Cell Cardiol 24, 1115-1166.
28. Kayar, S.A., Hoppeler, H., Jones, J.H. et al. 1994. Capillary blood transit time in muscles in relation to body size and aerobic capacity. J Exp Biol 194, 69-81.
29. Kreuzer, F. 1970. Facilitated Diffusion of Oxygen and its Possible Significance; A Review. Respir Physiol 9, 1-30.
30. Lawrie, R. 1953. The activity of the cytochrome system in muscle and its relation to myoglobin. Biochem J 55, 298-305.
31. Lindbom, L., Tuma, R.F. & Arfors, K.E. 1980. Influence of oxygen on perfused capillary density and capillary red cell velocity in rabbit skeletal muscle. Microvasc Res 19, 197-208.
32. Mathieu, O., Krauer, R., Hoppeler, H. et al. 1981. Design of the mammalian respiratory system. VII. Scaling mitochondrial volume in skeletal muscle to body mass. Respir Physiol 44 (1), 113-128.
33. Meyer, R.A., Sweeney, H.L. & Kushmerick, M.J. 1984. A simple analysis of the 'phosphocreatine shuttle' Am J Physiol 246, C365-C377.
34. Molé, P.A., Chung, Y., Tran, T.K., Sailasuta, N., Hurd, R. & Jue, T. 1999. Myoglobin desaturation with exercise intensity in human gastrocnemius muscle. Am J Physiol 277, R173-R180.
35. Noyszewski, E.A., Chen, E.L., Reddy, R., Wang, Z. & Leigh, J.S. 1997. A simplified sequence for observing deoxymyoglobin signals in vivo: Myoglobin excitation with dynamic unexcitation and saturation of water and fat. Mag Res Med 38, 788-792.
36. Papadopoulos, S., Jurgens, K.D. & Gros, G. 1995. Diffusion of myoglobin in skeletal muscle cells - dependence on fibre type, contraction and temperature. Pflugers Arch 430 (4), 519-525.
37. Popel, A.S. 1989. Theory of oxygen transport to tissue. Crit Rev Biomed Eng 17, 257-321.
38. Radergran, G. 1997. Ultrasound Doppler estimates of femoral artery blood flow during dynamic knee-extensor exercise in humans. J Appl Physiol 83, 1383-1388.
39. Radford, N.B., Fina, M., Benjamin, I.J. et al. 1996. Cardioprotective effects of 70-kDa heat shock protein in transgenic mice. Proc Natl Acad Sci USA 93 (6), 2339-2342.
40. 2 and bioenergetic measurements in skeletal muscle: The role of exercise paradigm. Am J Physiol 278, in press.
41. 2 consumption in trained skeletal muscle. J Appl Physiol 87, 325-331.
42. 2 transport. J Clin Invest 96, 1916-1926.
43. 2 during single leg knee extensor exercise in humans. Am J Physiol 268, H1453-H1461.
44. 2. J Appl Physiol 85, 627-634.
45. Richardson, R.S., Frank, R.L. & Haseler, L.J. 1998b. Dynamic knee-extensor and cycle exercise: Functional MRI of muscular activity. Int J Sports Med 19, 182-187.
46. 2 extraction compromised? J Appl Physiol 75 (4), 1911-1916.
47. Schmidt-Neilsen, K. & Larimer, J.L. 1958. Oxygen dissociation curves of mammalian blood in relation to body size. Am J Physiol 195, 424-428.
48. Seeherman, H.J., Taylor, C.R., Maloiy, G.M. & Armstrong, R.B. 1981. Design of the mammalian respiratory system. II Measuring maximum aerobic capacity. Respir Physiol 44 (1), 11-23.
49. 2max. J Appl Physiol 77, 671-678.
50. Thomas, A. & Morris, P.G. 1981. The effects of NMR exposure on living organisms. A microbial assay. Br J Radiol 54, 615-621.
51. Vanderbourne, K., McCully, K., Kakihira, H. et al. 1991. Metabolic heterogeneity in human calf muscle during maximal exercise. Proc Natl Acad Sci USA 88, 5714-5718.
52. Wagner, P.D. 1992. Gas exchange and peripheral diffusion limitation. Med Sci Sports Exer 24 (1), 54-58.
53. 2max. Respir Physiol 93, 221-237.
54. Wagner, P.D., Roca, J., Hogan, M.C., Poole, D.C., Debout, D.E. & Haab, P. 1990. Experimental support of the theory of diffusion limitation of maximum oxygen uptake. In: Oxygen Transport to Tissue, pp. 825-833. XII. Plenum Press, New York, NY.
55. Wang, Z., Noyszewski, E.A. & Leigh, J.S. 1990. In vivo MRS measurement of deoxymyoglobin in human forearms. Mag Res Med 14, 562-567.
56. Wang, D., Kreutzer, U., Chung, Y. & Jue, T. 1997. Myoglobin and hemoglobin rotational diffusion in the cell. Biophys J 73 (5), 2764-2770.
57. Wasserman, K. 1984. The anaerobic threshold measurement to evaluate exercise performance. Am Rev Resp Dis 61, 260-270.
58. Wilson, D.F., Erecinska, M., Drown, C. & Silver, I.A. 1977. Effect of oxygen tension on cellular energetics. Am J Physiol 233, C135-C140.
59. Wittenberg, J.B. 1970. Myoglobin-facilitated oxygen diffusion: role of myoglobin in oxygen entry into muscle. Physiol Rev 50, 559-636.
60. Wittenberg, B.A. & Wittenberg, J.B. 1975. Role of Myoglobin in the oxygen supply to red skeletal muscle. J Biol Chem 250, 9038-9043.
61. Wittenberg, J. & Wittenberg, B. 1989. Transport of oxygen in muscle. Annu Rev Physiol 51, 857-878.
62. Wittenberg, J.B. & Wittenberg, B.A. 1990. Mechanisms of cytoplasmic hemoglobin and myoglobin function. Annu Rev Biophys Chem 19, 217-241.