The role of the A2A adenosine receptor subtype in functional hyperaemia in the hindlimb of anaesthetized cats

Journal of Physiology

Volumn 492, Issue 2, 1996, Pages 495-503

  Poucher, S M ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

8 PHENYLTHEOPHYLLINE; ADENOSINE A2 RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; BLOOD FLOW; CAT; CONTROLLED STUDY; ELECTROSTIMULATION; EXTENSOR DIGITORUM LONGUS MUSCLE; FEMORAL NERVE; HINDLIMB; HYPEREMIA; MALE; MUSCLE CONTRACTION; MUSCLE ISOMETRIC CONTRACTION; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; SCIATIC NERVE; TIBIALIS ANTERIOR MUSCLE;

ADENOSINE; ANIMALS; ARTERIES; CATS; GASES; HINDLIMB; HYDROGEN-ION CONCENTRATION; HYPEREMIA; ISOMETRIC CONTRACTION; MALE; MUSCLES; RECEPTORS, PURINERGIC P1; REGIONAL BLOOD FLOW; THEOPHYLLINE; TRIAZINES; TRIAZOLES;

EID: 0030009387     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1996.sp021324     Document Type: Article

References (38)

1. BALLARD, H. J., COTTERRELL, D. & KARIM, F. (1987a). Venous adenosine content and vascular responses in dog hindlimb skeletal muscle during twitch contraction. Quarterly Journal of Experimental Physiology 72, 461-471.
2. BALLARD, H. J., COTTERRELL, D. & KARIM, F. (1987b). Appearance of adenosine in venous blood from contracting skeletal muscle and its role in vasodilatation in the dog. Journal of Physiology 387, 401-413.
3. BELLONI, F. L., PHAIR, R. D. & SPARKS, H. V. (1979). The role of adenosine in prolonged vasodilatation following flow restriction exercise of canine muscle. Circulation Research 44, 759-766.
4. BOCKMAN, E. L., BERNE, R. M. & RUBIO, R. (1975). Release of adenosine and lack of release of ATP from contracting skeletal muscle. Pflügers Archiv 355, 229-241.
5. BOCKMAN, E. L. & MCKENZIE, J. E. (1983). Tissue adenosine content in active soleus and gracilis muscles of cats. American Journal of Physiology 244, H552-559.
6. BOCKMAN, E. L., STEFFEN, R. P., MCKESNZIE, J. E., YACHNIS, A. T. & HADDY, F. J. (1982). Adenosine and active hyperaemia in dog gracilis muscle. Federation Proceedings 41, 1680.
7. BUNKER, J. P. & VANDAM, L. D. (1965). Effects of anaesthesia on metabolism and cellular functions. Pharmacological Reviews 17, 183-363.
8. COLLIS, M. G., PALMER, D. B. & BAXTER, G. S. (1986). Evidence that the intracellular effects of adenosine on the aorta are mediated by inosine. European Journal of Pharmacology 121, 141-145.
9. COTTERRELL, D. & KARIM, F. (1982). Effects of adenosine and its analogues on the perfused hind limb artery and vein of anaesthetised dogs. Journal of Physiology 323, 473-482.
10. DALY, J. W. (1985). Adenosine receptors. Advances in Cyclic Nucleotide Protein Phosphatase Research 19, 29-46.
11. DRURY, A. N. & SZENT-GYÖRGYI, A. (1929). The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart. Journal of Physiology 68, 213-236.
12. GOONEWARDENE, I. P. & KARIM, F. (1991). Attenuation of exercise vasodilatation by adenosine deaminase in anaesthetized dogs. Journal of Physiology 442, 65-79,
13. 2b subtype. British Journal of Pharmacology 102, 198P (Abstract).
14. HEDQVIST, P. & FREDHOLM, B. B. (1976). Effects of adenosine on adrenergic neurotransmission; pre-junctional inhibition and post-junctional enhancement. Naunyn-Schmiedeberg's Archives of Pharmacology 293, 217-223.
15. IMAI, S., RILEY, A. L. & BERNE, R. M. (1964). Effect of ischaemia on adenine nucleotides in cardiac and skeletal muscle. Circulation Research 15, 443-450.
16. KARIM, F., BALLARD, H. J. & COTTERRELL, D. (1988). Changes in adenosine release and blood flow in the contracting dog gracilis muscle. Pflügers Archiv 412, 106-112.
17. KEDDIE, J. R., POUCHER, S. M., SHAW, G. R. & COLLIS, M. G. (1995). The in vivo cardiovascular pharmacology of ZM241385, a novel, non-xanthine, adenosine antagonist. British Journal of Pharmacology 115, 52P.
18. KOCH, L. G., BRITTON, S. L. & METTING, P. J. (1990). Adenosine is not essential for exercise hyperaemia in the hindlimb of conscious dogs. Journal of Physiology 429, 63-75.
19. LEMBECK, F. & DONNERER, J. (1981). Post occlusive cutaneous vasodilation mediated by substance P. Naunyn-Schmiedeberg's Archives of Pharmacology 316, 165-171.
20. LONDOS, C., WOLFF, J. & COOPER, D. M. F. (1982). Adenosine receptors and adenylate cyclase interactions. In Regulatory Function of Adenosine., ed. BERNE, R. M., RALL, T. W. & RUBIO, R., pp. 17-32. Martinus Nijhoff, Boston, USA.
21. 2 adenosine receptor subtypes. European Journal of Pharmacology 214, 199-205.
22. 2b receptors in the guinea-pig aorta. European Journal of Pharmacology 216, 235-242.
23. MOHRMAN, D. E. & HELLER, L. J. (1984). Effect of aminophylline on adenosine and exercise dilation of rat cremaster muscles. American Journal of Physiology 246, H592-600.
24. NALLY, J. E., KEDDIE, J. R., SHAW, G. R. & COLLIS, M. G. (1991). Investigation of the adenosine receptor responsible for bradycardia and vasodilatation in the dog. British Journal of Pharmacology 102, 340P.
25. NGAI, A. C., IBAYASHI, S., MENO, J. R. & WINN, H. R. (1987). Cerebral vasoactivity of inosine: potentiation of adenosine induced vasodilatation. Federation Proceedings 46, 800.
26. PERSSON, C. G. A., ERJEFALT, I. & KARLSSON, J. A. (1981). Adenosine antagonism, a less desirable aspect of xanthine asthma drugs. Acta Pharmacologia et Toxicologica 49, 317-320.
27. 2a selective adenosine antagonist. British Journal of Pharmacology 115, 1096-1102.
28. POUCHER, S. M., NOWELL, C. G. & COLLIS, M. G. (1990). The role of adenosine in exercise hyperaemia of the gracilis muscle in anaesthetized cats. Journal of Physiology 427, 19-29.
29. PREMONT, J., PEREZ, G., BLANC, G., TASSIN, J. P., THIERRY, H. M., HERVE, D. & BOCKHAET, J. (1979). Adenosine-sensitive adenylate cyclase in rat brain homogenates: kinetic characteristics, specificity, topographical, subcellular, and cellular distribution. Molecular Pharmacology 16, 790-804.
30. PROCTOR, K. G. (1984). Reduction of contraction-induced arteriolar vasodilation by adenosine deaminase or theophylline. American Journal of Physiology 247, H195-205.
31. RALL, T. W. (1982). Evaluation of the mechanism of action of methylxanthines: from calcium mobilisation to antagonism of adenosine receptors. Pharmacology 24, 277-287.
32. RUBIO, R., BERNE, R. M. & DOBSON, J. G. (1973). Sites of adenosine production in cardiac and skeletal muscle. American Journal of Physiology 216, 56-62.
33. SCHWARTZ, L. M. & MCKENZIE, J. M. (1990). Adenosine and active hyperaemia in soleus and gracilis muscle of cats. American Journal of Physiology 259, H1295-1304.
34. SEBASTIAO, A. M. & RIBIERO, J. A. (1988). On the adenosine receptor and adenosine inactivation at the rat diaphragm neuromuscular junction. British Journal of Pharmacology 94, 109-120.
35. SHEPHEARD, S. L., WILLIAMSON, D. J., HILL, R. G. & HARGREAVES, R. J. (1993). The non-peptide neurokinin-1 receptor antagonist RP67580 blocks neurogenic plasma extravasation in the duramater of rats. British Journal of Pharmacology 108, 11-12.
36. THOMSON, L. P., GORMAN, M. W. & SPARKS, H. V. (1986). Aminophylline and intestinal adenosine during sustained exercise hyperaemia. American Journal of Physiology 251, H1232-1243.
37. 2 adenosine receptor. Journal of Medicinal Chemistry 34, 1334-1339.
38. VERHAEGHE, R. H., VANHOUTTE, P. M. & SHEPHERD, J. T. (1977). Inhibition of sympathetic neurotransmission in canine blood vessels by adenosine and adenine nucleotides. Circulation Research 40, 208-215.