Antineoplastic Agents. 499. Synthesis of Hystatin 2 and Related 1H-Benzo[de][1,6]-naphthyridinium Salts from Aaptamine

Journal of Medicinal Chemistry

Volumn 47, Issue 7, 2004, Pages 1775-1782

  Pettit, George R ^a   Hoffmann, Holger ^a   Herald, Delbert L ^a   Blumberg, Peter M ^b   Hamel, Ernest ^c   Schmidt, Jean M ^a   Chang, Yung ^a   Pettit, Robin K ^a   Lewin, Nancy E ^b   Pearce, Larry V ^b  

^a ARIZONA STATE UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 BIS(3,4,5 TRIMETHOXYBENZYL) 8,9 DIMETHOXY 4H BENZO[DE][1,6]NAPHTHYRIDINIUM BROMIDE; 1,4 BIS(4 METHOXYBENZYL) 8,9 DIMETHOXY 4H BENZO[DE][1,6]NAPHTHYRIDINIUM BROMIDE; 1H BENZO[DE][1,6]NAPHTHYRIDINIUM DERIVATIVE; AAPTAMINE; AAPTAMINE DERIVATIVE; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; HYSTATIN 2; NAPHTHYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BENZYLATION; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA MICROARRAY; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; LYMPHATIC LEUKEMIA; MICROCOCCUS LUTEUS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NEISSERIA GONORRHOEAE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; NAPHTHYRIDINES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 12144291053     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030070r     Document Type: Article

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