-
1
-
-
0023836456
-
Most drugs that reverse multidrug resistance also inhibit photoaffinity labeling ot P-glycoprotein by a vinblastine analog
-
Akiyama S. Cornwell MM, Kuwano M, Pastan I and Gottesman MM (1988) Most drugs that reverse multidrug resistance also inhibit photoaffinity labeling ot P-glycoprotein by a vinblastine analog. Mol Pharmacol 33: 144-147
-
(1988)
Mol Pharmacol
, vol.33
, pp. 144-147
-
-
Akiyama, S.1
Cornwell, M.M.2
Kuwano, M.3
Pastan, I.4
Gottesman, M.M.5
-
2
-
-
0026522722
-
Fagaronine, a novel antileukemic alkaloid
-
Barret Y and Sauvaire Y (1992) Fagaronine, a novel antileukemic alkaloid. Phytother Res 6: 59-63
-
(1992)
Phytother Res
, vol.6
, pp. 59-63
-
-
Barret, Y.1
Sauvaire, Y.2
-
3
-
-
0024971222
-
Two different regions of P-glycoprotein [corrected] are photoaffinity-labeled by azidopine
-
published erratum appear in J Biol Chem 1990. 265: 4172
-
Bruggemann EP, Germann UA. Gottesman MM and Pastan I (1989) Two different regions of P-glycoprotein [corrected] are photoaffinity-labeled by azidopine [published erratum appear in J Biol Chem 1990. 265: 4172]. J Biol Chem 264: 15483-15488
-
(1989)
J Biol Chem
, vol.264
, pp. 15483-15488
-
-
Bruggemann, E.P.1
Germann, U.A.2
Gottesman, M.M.3
Pastan, I.4
-
4
-
-
0038134267
-
Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats
-
Cowan KH, Batist G, Tulpule A, Sinha BK and Myers CE (1986) Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats. Proc Natl Acad Sci USA 83: 9328-9332
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 9328-9332
-
-
Cowan, K.H.1
Batist, G.2
Tulpule, A.3
Sinha, B.K.4
Myers, C.E.5
-
5
-
-
0015893137
-
Active outward transport ot daunomycin in resistant Ehrlich ascites tumor cells
-
Dano K (1973) Active outward transport ot daunomycin in resistant Ehrlich ascites tumor cells. Biochim Biophys Res Acta 323: 466-483
-
(1973)
Biochim Biophys Res Acta
, vol.323
, pp. 466-483
-
-
Dano, K.1
-
6
-
-
0024583327
-
Direct correlanon between DNA topoisomerase II activity and cytotoxicity in adriamycin-sensitive and -resistant P388 leukemia cell lines
-
Deffie AM, Batra JK and Goldenberg GJ (1989) Direct correlanon between DNA topoisomerase II activity and cytotoxicity in adriamycin-sensitive and -resistant P388 leukemia cell lines. Cancer Res 49: 58-62
-
(1989)
Cancer Res
, vol.49
, pp. 58-62
-
-
Deffie, A.M.1
Batra, J.K.2
Goldenberg, G.J.3
-
7
-
-
0021856764
-
Reduced drug accumulation in multiply drug-resistant human KB carcinoma cell lines
-
Fojo A, Akiyama S. Gottesman MM and Pastan I (1985) Reduced drug accumulation in multiply drug-resistant human KB carcinoma cell lines. Cancer Res 45: 3002-3007
-
(1985)
Cancer Res
, vol.45
, pp. 3002-3007
-
-
Fojo, A.1
Akiyama, S.2
Gottesman, M.M.3
Pastan, I.4
-
8
-
-
10544223738
-
A topoisomerase II inhibitor, NK109, induces DNA single- And double-strand breaks and apoptosis
-
Fukuda M. Inomata M, Nishio K, Fukuoka K, Kanzawa F, Arioka H, Ishida T, Fukumoto H, Kurokawa H, Oka M and Saijo N (1996) A topoisomerase II inhibitor, NK109, induces DNA single- and double-strand breaks and apoptosis Jap J Cancer Res 87: 1086-1091
-
(1996)
Jap J Cancer Res
, vol.87
, pp. 1086-1091
-
-
Fukuda, M.1
Inomata, M.2
Nishio, K.3
Fukuoka, K.4
Kanzawa, F.5
Arioka, H.6
Ishida, T.7
Fukumoto, H.8
Kurokawa, H.9
Oka, M.10
Saijo, N.11
-
9
-
-
0024279163
-
The multidrug transporter, a double-edged sword
-
Gottesman MM and Pastan I (1988) The multidrug transporter, a double-edged sword (Review). J Biol Chem 263: 12163-12166
-
(1988)
J Biol Chem
, vol.263
, pp. 12163-12166
-
-
Gottesman, M.M.1
Pastan, I.2
-
10
-
-
0345273427
-
Synthesis of fagaridine, a phenolic benzo[c]phenanthridine alkaloid
-
Hanaoka M, Yamagishi H and Murai C (1985) Synthesis of fagaridine, a phenolic benzo[c]phenanthridine alkaloid. Chem Pharm Bull 33: 1763-1765
-
(1985)
Chem Pharm Bull
, vol.33
, pp. 1763-1765
-
-
Hanaoka, M.1
Yamagishi, H.2
Murai, C.3
-
11
-
-
0023902188
-
Establishment and characterization of cisplatin- Resistant sublines ol human lung cancer cell lines
-
Hong WS, Saijo N, Sasaki Y, Minato K. Nakano H, Nakagawa K, Fujiwara Y, Nomura K andTwentyman PR (1988) Establishment and characterization of cisplatin- resistant sublines ol human lung cancer cell lines. Int J Cancer 41: 462-167
-
(1988)
Int J Cancer
, vol.41
, pp. 462-1167
-
-
Hong, W.S.1
Saijo, N.2
Sasaki, Y.3
Minato, K.4
Nakano, H.5
Nakagawa, K.6
Fujiwara, Y.7
Nomura, K.8
Twentyman, P.R.9
-
12
-
-
0025335824
-
3′-Deamino-3′- Morpholino-13-deoxo-10-hydroxycarminomycin conquers multidrug resistance by rapid influx following higher frequency of formation of DNA single- and double-strand breaks
-
Horichi N, Tapiero H, Sugimoto Y, Bungo M, Nishiyama M, Fourcade A, Lampidis TJ, Kasahara K, Sasaki Y, Takahashi T and Saijo N (1990) 3′-Deamino-3′- morpholino-13-deoxo-10-hydroxycarminomycin conquers multidrug resistance by rapid influx following higher frequency of formation of DNA single- and double-strand breaks. Cancer Res 50: 4698-4701
-
(1990)
Cancer Res
, vol.50
, pp. 4698-4701
-
-
Horichi, N.1
Tapiero, H.2
Sugimoto, Y.3
Bungo, M.4
Nishiyama, M.5
Fourcade, A.6
Lampidis, T.J.7
Kasahara, K.8
Sasaki, Y.9
Takahashi, T.10
Saijo, N.11
-
13
-
-
0027305406
-
Glutathione-associated cis- Diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance
-
Ishikawa T and Ali-Osman F (1993) Glutathione-associated cis- diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance. J Biol Chem 268: 201 16-20125
-
(1993)
J Biol Chem
, vol.268
, pp. 20116-20125
-
-
Ishikawa, T.1
Ali-Osman, F.2
-
14
-
-
0007481274
-
A novel benzo[c]phenanthridine derivative, NK109, is a highly active anticancer agent and DNA topoisomerase II inhibitor
-
Kabasawa T, Kobayashi F, Ekimoto H, Suzuki M and Hanaoka M (1996) A novel benzo[c]phenanthridine derivative, NK109, is a highly active anticancer agent and DNA topoisomerase II inhibitor. Proc Am Assoc Cancer Res 37: 427
-
(1996)
Proc Am Assoc Cancer Res
, vol.37
, pp. 427
-
-
Kabasawa, T.1
Kobayashi, F.2
Ekimoto, H.3
Suzuki, M.4
Hanaoka, M.5
-
15
-
-
0019411180
-
Antitumor activity of 3′,5′-diesters of 5-fluoro-2′-deoxyuridine against murinc leukemia L 1210 cells
-
Kanzawa F, Hoshi A, Kuretani K, Saneyoshi M and Kawaguehi T (1981) Antitumor activity of 3′,5′-diesters of 5-fluoro-2′-deoxyuridine against murinc leukemia L 1210 cells. Cancer Chemother Phamacol 6; 19-23
-
(1981)
Cancer Chemother Phamacol
, vol.6
, pp. 19-23
-
-
Kanzawa, F.1
Hoshi, A.2
Kuretani, K.3
Saneyoshi, M.4
Kawaguehi, T.5
-
16
-
-
0020065191
-
Murine lymphoma L5I 78Y cells resistant to purine antagonists: Differences in cross-resistance to thioguanine-platinum(II) and selenoguatnine-platinum(II)
-
Kanzawa F Maeda M, Sasaki T, Hoshi A and Kuretani K (1982) Murine lymphoma L5I 78Y cells resistant to purine antagonists: differences in cross-resistance to thioguanine-platinum(II) and selenoguatnine-platinum(II). J Natl Cancer lnst 68: 287-291
-
(1982)
J Natl Cancer Lnst
, vol.68
, pp. 287-291
-
-
Kanzawa, F.1
Maeda, M.2
Sasaki, T.3
Hoshi, A.4
Kuretani, K.5
-
17
-
-
0025084410
-
Establishment of a camptothecin analogue (CPT- 11)-resistant cell line of human non-small cell lung cancer: Characterization and mechanism of resistance
-
Kanzawa F, Sugimoto Y, Minato K, Kasahara K, Bungo M, Nukagawa K, Fujiwara Y, Liu LF and Saijo N (1990) Establishment of a camptothecin analogue (CPT- 11)-resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance. Cancer Res 50: 5919-5924
-
(1990)
Cancer Res
, vol.50
, pp. 5919-5924
-
-
Kanzawa, F.1
Sugimoto, Y.2
Minato, K.3
Kasahara, K.4
Bungo, M.5
Nukagawa, K.6
Fujiwara, Y.7
Liu, L.F.8
Saijo, N.9
-
18
-
-
0029035461
-
Antitumor activities of a new indolocarbazole substance. NB-506, and establishment of NB-506-resistant cell lines. SBC-3/NB
-
Kanzawa F, Nishio K, Kubota N and Saijo N (1995) Antitumor activities of a new indolocarbazole substance. NB-506, and establishment of NB-506-resistant cell lines. SBC-3/NB. Cancer Res 55: 2806-2813
-
(1995)
Cancer Res
, vol.55
, pp. 2806-2813
-
-
Kanzawa, F.1
Nishio, K.2
Kubota, N.3
Saijo, N.4
-
19
-
-
0024470862
-
Induction of endonucleolytic DNA cleavage in human acute myelogcnous leukemia cells by etoposide, camptothecin, and cytotoxic anticancer drugs: A cautionary note
-
Kaufmann SH ( 1989) Induction of endonucleolytic DNA cleavage in human acute myelogcnous leukemia cells by etoposide, camptothecin, and cytotoxic anticancer drugs: a cautionary note. Cancer Res 49: 5870-5878
-
(1989)
Cancer Res
, vol.49
, pp. 5870-5878
-
-
Kaufmann, S.H.1
-
20
-
-
0023920021
-
Benzyne cyclization route to benzo[c]phenanthridine alkaloids. Synthesis of chelerythrine, decarine, and nilidine
-
KessarSV, Gupta YP, Balakrishnan P, Sawal KK, Mohammad T and Dutt M (1988) Benzyne cyclization route to benzo[c]phenanthridine alkaloids. Synthesis of chelerythrine, decarine, and nilidine. J Org Chem 53, 1708-1713
-
(1988)
J Org Chem
, vol.53
, pp. 1708-1713
-
-
Kessar, S.V.1
Gupta, Y.P.2
Balakrishnan, P.3
Sawal, K.K.4
Mohammad, T.5
Dutt, M.6
-
21
-
-
0023143929
-
Establishment of adriamycin-resistant human small-cell lung cancer cells in culture: Analysis of the mechanism of resistance and cross-resistance
-
Kimura I, Ohnoshi T, Hiraki S and Miyamoto H (1987) Establishment of adriamycin-resistant human small-cell lung cancer cells in culture: analysis of the mechanism of resistance and cross-resistance. Jpn J Cancer Chemother 14: 830-836
-
(1987)
Jpn J Cancer Chemother
, vol.14
, pp. 830-836
-
-
Kimura, I.1
Ohnoshi, T.2
Hiraki, S.3
Miyamoto, H.4
-
22
-
-
0028051992
-
In vitro and in vivo effects of cisplatin and etoposide in combination on small cell lung cancer cell lines
-
Kondo H, Kanzawa F, Nishio K, Saito S and Saijo N (1994) In vitro and in vivo effects of cisplatin and etoposide in combination on small cell lung cancer cell lines. Jpn J Cancer Res 85: 1050-1056
-
(1994)
Jpn J Cancer Res
, vol.85
, pp. 1050-1056
-
-
Kondo, H.1
Kanzawa, F.2
Nishio, K.3
Saito, S.4
Saijo, N.5
-
23
-
-
0028341457
-
Characterization of an etoposide-resistant human ovarian cancer cell line
-
Kubota N, Nishio K, Takeda Y, Ohmori T. Funayatma Y, Ogasawara H, Ohira T, Kunikane H, Terashima Y and Saijo N (1994) Characterization of an etoposide-resistant human ovarian cancer cell line. Cancer Chemother Pharmacol 34: 183-190
-
(1994)
Cancer Chemother Pharmacol
, vol.34
, pp. 183-190
-
-
Kubota, N.1
Nishio, K.2
Takeda, Y.3
Ohmori, T.4
Funayatma, Y.5
Ogasawara, H.6
Ohira, T.7
Kunikane, H.8
Terashima, Y.9
Saijo, N.10
-
24
-
-
0027369170
-
The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II
-
Larsen AK, Grondard L, Couprie J, Desoize B, Comoe L, Jardillier JC and Riou JF (1993) The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II. Biochem Pharmacol 46: 1403-1412
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 1403-1412
-
-
Larsen, A.K.1
Grondard, L.2
Couprie, J.3
Desoize, B.4
Comoe, L.5
Jardillier, J.C.6
Riou, J.F.7
-
25
-
-
0001498255
-
Eukaryotic DNA topoiisomerases: Two forms of type I DNA topoisomerases from HeLa cell nuclei
-
Liu LF and Miller KG (1981) Eukaryotic DNA topoiisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei. Proc Natl Acad Sci USA 78: 3487-3491
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 3487-3491
-
-
Liu, L.F.1
Miller, K.G.2
-
26
-
-
0021112878
-
Cleavage of DNA by mammalian DNA topoisomerase II
-
Liu LF, Rowe TC, Yang L, Tewey KM and Chen GL ( 1983) Cleavage of DNA by mammalian DNA topoisomerase II. J Biol Chem 258: 15365-15370
-
(1983)
J Biol Chem
, vol.258
, pp. 15365-15370
-
-
Liu, L.F.1
Rowe, T.C.2
Yang, L.3
Tewey, K.M.4
Chen, G.L.5
-
27
-
-
0019321213
-
Decatenation ol kineloplast DNA by topoisomerases
-
Marini JC, Miller KG and Englund PT (1980) Decatenation ol kineloplast DNA by topoisomerases. J Biol Chem 255: 4976-4979
-
(1980)
J Biol Chem
, vol.255
, pp. 4976-4979
-
-
Marini, J.C.1
Miller, K.G.2
Englund, P.T.3
-
28
-
-
0024997214
-
Characterization of an ctoposide-resistant human small-cell lung cancer cell line
-
Minato K. Kanzawa F, Nishio K, Nakagawa K, Fujiwara Y and Saijo N (1990) Characterization of an ctoposide-resistant human small-cell lung cancer cell line. Cancer Chemother Pharmacol 26: 313-317
-
(1990)
Cancer Chemother Pharmacol
, vol.26
, pp. 313-317
-
-
Minato, K.1
Kanzawa, F.2
Nishio, K.3
Nakagawa, K.4
Fujiwara, Y.5
Saijo, N.6
-
29
-
-
0021333644
-
Mechanism of antitumor drug action: Poisoning of mammalian DNA topoisomerase II on DNA by 4′-9- Acridinylaminol-methanesulfon-m-aniside
-
Nelson EM, Tewey KM and Liu LF (1984) Mechanism of antitumor drug action: Poisoning of mammalian DNA topoisomerase II on DNA by 4′-(9- acridinylaminol-methanesulfon-m-aniside. Proc Natl Acad Sci USA 81: 1361-1365
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 1361-1365
-
-
Nelson, E.M.1
Tewey, K.M.2
Liu, L.F.3
-
30
-
-
0025144278
-
Cross-resistance to tumour promoters in human cancer cell lines resistant to adriamycin or cisplatin
-
Nishio K, Sugimoto Y, Nakagawa K, Niimi S, Fujiwara Y, Bungo M, Kasahara K, Fujiki H and Saijo N (1990) Cross-resistance to tumour promoters in human cancer cell lines resistant to adriamycin or cisplatin. Br J Cancer 62: 415-419
-
(1990)
Br J Cancer
, vol.62
, pp. 415-419
-
-
Nishio, K.1
Sugimoto, Y.2
Nakagawa, K.3
Niimi, S.4
Fujiwara, Y.5
Bungo, M.6
Kasahara, K.7
Fujiki, H.8
Saijo, N.9
-
31
-
-
0027499265
-
The mechanism of the difference in cellular uptake of platinum derivatives in non-small cell lung cancer cell line (PC-14) and its cisplatin-resistant subline (PC- 14/CDDP)
-
Ohmori T, Morikage T, Sugimoto Y, Fujiwara Y, Kasahara K, Nishio K, Ohta S, Sasaki Y, Takahashi T and Saijo N (1993 ) The mechanism of the difference in cellular uptake of platinum derivatives in non-small cell lung cancer cell line (PC-14) and its cisplatin-resistant subline (PC- 14/CDDP). Jpn J Cancer Res 84: 83-92
-
(1993)
Jpn J Cancer Res
, vol.84
, pp. 83-92
-
-
Ohmori, T.1
Morikage, T.2
Sugimoto, Y.3
Fujiwara, Y.4
Kasahara, K.5
Nishio, K.6
Ohta, S.7
Sasaki, Y.8
Takahashi, T.9
Saijo, N.10
-
32
-
-
0021688805
-
Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage
-
Ross W, RoweT, Glisson B, Yalowich J and Liu LF (1984) Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage. Cancer Res 44: 5857-5860
-
(1984)
Cancer Res
, vol.44
, pp. 5857-5860
-
-
Ross, W.1
Rowe, T.2
Glisson, B.3
Yalowich, J.4
Liu, L.F.5
-
33
-
-
0023226943
-
Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for calcium channel blockers
-
Safa AR, Glover CJ, Sewell JL, Meyers MB, Biedler JL and Felsted RL (1987) Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for calcium channel blockers. J Biol Chem 262: 7884-7888
-
(1987)
J Biol Chem
, vol.262
, pp. 7884-7888
-
-
Safa, A.R.1
Glover, C.J.2
Sewell, J.L.3
Meyers, M.B.4
Biedler, J.L.5
Felsted, R.L.6
-
34
-
-
0018200435
-
Mechanisms of resistance to daunorubicin in Ehrlich ascites tumor cells
-
Skovsgaard T (1978) Mechanisms of resistance to daunorubicin in Ehrlich ascites tumor cells. Cancer Res 38: 1785-1791
-
(1978)
Cancer Res
, vol.38
, pp. 1785-1791
-
-
Skovsgaard, T.1
-
35
-
-
0021192054
-
Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II
-
Tewey KM, Chen GL, Nelson EM and Liu LF (1984) Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II. J Biol Chem 259: 9182-9187
-
(1984)
J Biol Chem
, vol.259
, pp. 9182-9187
-
-
Tewey, K.M.1
Chen, G.L.2
Nelson, E.M.3
Liu, L.F.4
-
36
-
-
0001115051
-
Fagaridine: A phenolic benzophenanthridine alkaloid from Fagara xanthoxyloides
-
Totlo FG and Mensah IA (1973) Fagaridine: a phenolic benzophenanthridine alkaloid from Fagara xanthoxyloides. Phytochemistry 12: 2315-2317
-
(1973)
Phytochemistry
, vol.12
, pp. 2315-2317
-
-
Totlo, F.G.1
Mensah, I.A.2
-
37
-
-
0019332581
-
Covalent bounds between protein and DNA
-
Tse YC, Kirkegaard K and Wang JC (1980) Covalent bounds between protein and DNA, J Biol Chem 255: 5560-5565
-
(1980)
J Biol Chem
, vol.255
, pp. 5560-5565
-
-
Tse, Y.C.1
Kirkegaard, K.2
Wang, J.C.3
-
38
-
-
0022475690
-
Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones
-
Tsuruo T, lida, HS, Kawabata H, Oh-Hata T, Hamada H and Utakoji T (1986) Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones. Jpn J Cancer Res 77: 682-692
-
(1986)
Jpn J Cancer Res
, vol.77
, pp. 682-692
-
-
Tsuruo, T.1
Lida, H.S.2
Kawabata, H.3
Oh-Hata, T.4
Hamada, H.5
Utakoji, T.6
-
39
-
-
0021891888
-
DNA topoisomerases
-
Wang JC (1985) DNA topoisomerases, Annu Rev Biochem 54: 665-697
-
(1985)
Annu Rev Biochem
, vol.54
, pp. 665-697
-
-
Wang, J.C.1
-
40
-
-
0027433723
-
Inhibition of topoisomerase I function by nitidine and fagaronine
-
Wang LK, Johnson RK and Hecht CM ( 1993) Inhibition of topoisomerase I function by nitidine and fagaronine. Chem Res Toxocol 6: 813-818
-
(1993)
Chem Res Toxocol
, vol.6
, pp. 813-818
-
-
Wang, L.K.1
Johnson, R.K.2
Hecht, C.M.3
-
41
-
-
0023871170
-
Azidopine photoaffinity labeling of multidrug resistance-associated glycoproteins
-
Yang CP. Mellado W and Horwitz SB ( 1988) Azidopine photoaffinity labeling of multidrug resistance-associated glycoproteins. Biochem Pharmacol 37: 1417-1421
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 1417-1421
-
-
Yang, C.P.1
Mellado, W.2
Horwitz, S.B.3
-
42
-
-
0029946865
-
Antitumor activity of daphnane- Type diterpene gnidimacrin isolated from stellera cheamaejasme L
-
Yoshida M, Feng W, Saijo N and Ikekawa T (1996) Antitumor activity of daphnane- type diterpene gnidimacrin isolated from stellera cheamaejasme L. Int J Cancer 66:268-273
-
(1996)
Int J Cancer
, vol.66
, pp. 268-273
-
-
Yoshida, M.1
Feng, W.2
Saijo, N.3
Ikekawa, T.4
|