Antioxidant, a pro-oxidant and cytotoxic effects of Achyrocline satureioides extracts

Life Sciences

Volumn 74, Issue 23, 2004, Pages 2815-2826

  Polydoro, M ^a   De Souza, K C B ^a   Andrades, M E ^a   Da Silva, E G ^a   Bonatto, F ^a   Heydrich, J ^a   Dal Pizzol, F ^a,b   Schapoval, E E S ^a   Bassani, V L ^a   Moreira, J C F ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

Author keywords

Achyrocline satureioides; Antioxidant potential; Flavonoids; ROS; TRAP

Indexed keywords

ACHYROCLINE SATUREIOIDES EXTRACT; ANTIOXIDANT; CYTOSTATIC AGENT; FLAVANOID; HERBACEOUS AGENT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACHYROCLINE; ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL CULTURE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOSTASIS; CYTOTOXICITY; DRUG DETERMINATION; DRUG EFFECT; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIPID PEROXIDATION; NONHUMAN; PLASMA; SERTOLI CELL; TELOMERIC REPEAT AMPLIFICATION PROTOCOL;

ACHYROCLINE; ANIMALS; ANTIOXIDANTS; BRAZIL; CELL SURVIVAL; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; LIPID PEROXIDATION; MALE; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SERTOLI CELLS; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

ACHYROCLINE; ACHYROCLINE SATUREIOIDES; ASTERACEAE;

EID: 12144290977     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2003.09.073     Document Type: Article

References (30)

1. Arts M.J.T.J., Haenen H.P.V., Bast A. Masking of antioxidant capacity by the interaction of flavonoids with protein. Food and Chemical Toxicology. 39:2001;787-791.
2. Cao G., Sofic E., Prior R.L. Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships. Free Radical Biology and Medicine. 22(5):1997;749-760.
3. De Almeda E.R. Plantas medicinais Brasileiras, conhecimentos populares e científicos. 1997;Hemus, São Paulo, Brazil.
4. Desmarchelier C., Coussio J., Ciccia G. Antioxidant and Free Radical Scavenging Effects in Extracts of Medicinal Herb Achyrocline satureioides (Lam.) DC. (marcela). Brazilian Journal of Medical and Biological Research. 31:1998;1163-1170.
5. De Souza K.C.B., Schapoval E.E.S., Bassani V.L. LC determination of flavonoids: separation of quercetin, luteolin and 3-O-methylquercetin in Achyrocline satureioides preparations. Journal of Pharmaceutical and Biomedical Analysis. 28(3-4):2002;771-777.
6. Di Carlo G., Mascolo N., Izzo A.A., Capasso F. Flavonoids: Old and New Aspects of a Class of Natural Therapeutics Drugs. Life Sciences. 65(4):1999;337-353.
7. Draper H.H., Hadley M. Malondialdehyde Determination as Index of Lipid Peroxidation. Methods in Enzymology. 186:1990;421-431.
8. Ferraro G.E., Norbedo C., Coussio J.D. Polyphenols from Achyrocline satureioides. Phytochemistry. 20(8):1981;2053-2054.
9. Gugliucci A., Menini T. Three different pathways for human LDL oxidation are inhibited in vitro by water extracts of medicinal herb Achyrocline satureoides. Life Sciences. 71:2002;693-705.
10. Harbone J.B., Williams C.A. Advances in flavonoid research since 1992. Phytochemistry. 55:2000;481-504.
11. Hodnick W.F., Kung F.S., Roettger W.J., Bohmont C.W., Partidini R.S. Inhibition of mitochondrial respiration and production of toxic oxygen radicals by flavonoids. A structure activity study. Biochemical Pharmacology. 35(14):1986;2345-2357.
12. Ishige K., Schubert D., Sagara Y. Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms. Free Radical Biology and Medicine. 30(4):2001;433-446.
13. Kadarian C., Broussalis A.M., Miño J., Lopez P., Gorzalczany S., Ferraro G., Acevedo C. Hepatoprotective activity of Achirocline satureioides (Lam) D.C. Pharmacological Research. 45(1):2002.
14. Kuntz S., Wenzel U., Daniel H. Comparative analysis of effects of flavonoids on proliferation, cytotoxicity and apoptosis in human colon cancer cell lines. European Journal of Nutrition. 38:1999;133-142.
15. Lissi E., Salim-Hanna M., Pascual C., Del Castillo M.D. Evaluation of total antioxidant potential (TRAP) and total antioxidant reactivity from luminol-enhanced chemiluminescence measurements. Free Radical Biology and Medicine. 18(2):1995;153-158.
16. Lowry O.H., Rosebrough A.L., Randall R.J. Protein measurement with the folin phenol reagent. Journal of Biological Chemistry. 193:1951;265-275.
17. Manach C., Morad C., Crespy V., Demigné C., Texier O., Régérat F., Rémésy C. Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties. FEBS Letters. 426:1998;331-336.
18. Moreira J.C.F., Dal-Pizzol F., Von Endt D., Bernard E.A. Effect of retinol on cromatin structure in Sertoli cells: 1,10-phenanthroline inhibit the increased DNAse I sensitivity induced by retinol. Medical Science Research. 25:1997;635-638.
19. Moure A., Cruz J.M., Franco D., Domínguez J.M., Sineiro J., Domínguez H., Núñez M.J., Parajó J.C. Natural antioxidants from residual sources. Food Chemistry. 72:2001;145-171.
20. Musonda C.A., Chipman J.K. Quercetin inhibits hydrogen peroxide (H2O2)-induced NF-kappaB DNA binding activity and DNA damage in HepG2 cells. Carcinogenesis. 19:1998;1583-1589.
21. Ohshima H., Yoshie Y., Auriol S., Gilibert I. Antioxidant and pro-oxidant actions of flavonoids: effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxyl anion. Free Radical Biology and Medicine. 25:9:1998;1057-1065.
22. Oh T.Y., Lee J.S., Ahn B.O., Cho H., Kim W.B., Surch Y.J., Cho S.W., Hahm K.B. Oxidative damages are critical in pathogenesis of reflux esophagitis: implication of antioxidants in its treatment. Free Radical Biology and Medicine. 30:2001;905-915.
23. Rice-Evans C., Miller N. Measurement of the antioxidant status of dietary constituents, low density lipoproteins and plasma. Prostaglandins, Leukotrienes and Essential Fatty Acid. 75:1997;499-505.
24. Saggese D. 10th edn. Medicinal Herbs of Argentina. vol. 1:1959;189-191 Co Rosario, Antognazzi.
25. Schinella G.R., Troiani G., Dávila V., de Buschiazzo P.M., Tournier H.A. Antioxidant effects of an aqueous extract of Ilex paraguariensis. Biochemical Biophysical Research Communication. 269:2000;357-360.
26. Simões C.M.O., Schenkel E.P., Bauer L., Langeloh A.A. Pharmacological Investigations on Achyrocline satureioides (LAM.) D.C., Compositae. Journal of Ethnopharmacology. 22:1988;281-293.
27. Skibola C.F., Smith M.T. Potential heath impacts of excessive flavonoid intake. Free Radical Biology and Medicine. 29:2000;375-383.
28. Uliasz T.F., Hewett S.J. A microtiter trypan blue absorbance assay for the quantitative determination of excytotoxic neuronal injury in cell culture. Journal of Neuroscience Methods. 100:2000;157-163.
29. Wayner D.D.M., Burton G.W., Ingold K.U., Locke S. Quantitative measurement of the total, peroxyl radical-trapping antioxidant capability of human blood plasma by controlled peroxidation. The important contribution made by plasma proteins. FEBS Letters. 187:1985;33-37.
30. Yamamoto N., Moon J., Tsushida T., Nagao A., Terao J. Inhibitory Effect of Quercetin Metabolites and Their Related Derivatives on Copper Ion-Induced Lipid Peroxidacion in Human Low-density Lipoproteins. Archives of Biochemistry and Biophysics. 372(2):1999;347-354.