메뉴 건너뛰기




Volumn 64, Issue 5, 2004, Pages 1843-1852

Ammonium Trichloro(dioxoethylene-o,o′)tellurate (AS101) Sensitizes Tumors to Chemotherapy by Inhibiting the Tumor Interleukin 10 Autocrine Loop

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM TRICHLORO(DIOXYETHYLENE O,O')TELLURATE; ANTISENSE OLIGONUCLEOTIDE; INTERLEUKIN 10; PACLITAXEL; PROTEIN BCL 2; STAT3 PROTEIN; AMMONIUM TRICHLORO(DIOXOETHYLENE O,O' )TELLURATE; AMMONIUM TRICHLORO(DIOXOETHYLENE-O,O'-)TELLURATE; ANTINEOPLASTIC AGENT; DNA BINDING PROTEIN; ETHYLENE DERIVATIVE; STAT3 PROTEIN, HUMAN; STAT3 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

EID: 12144289718     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-3179     Document Type: Article
Times cited : (90)

References (47)
  • 1
    • 0030981706 scopus 로고    scopus 로고
    • The host-tumor immune conflict: From immunosuppression to resistance and destruction
    • Chouaib, S., Asselin-Paturel, C., Mami-Chouaib, F., Caignard, A., and Blay, J. Y. The host-tumor immune conflict: from immunosuppression to resistance and destruction. Immunol. Today, 18: 493-497, 1997.
    • (1997) Immunol. Today , vol.18 , pp. 493-497
    • Chouaib, S.1    Asselin-Paturel, C.2    Mami-Chouaib, F.3    Caignard, A.4    Blay, J.Y.5
  • 3
    • 0030950036 scopus 로고    scopus 로고
    • IL-10 is a growth factor for human melanoma cells and down-regulates HLA class I, HLA class II, and ICAM-1 molecules
    • Yue, F. Y., Dummer, R., Geertsen, R., Hofbauer, G., Laine, E., Manolio, S., and Burg, G. IL-10 is a growth factor for human melanoma cells and down-regulates HLA class I, HLA class II, and ICAM-1 molecules. Int. J. Cancer, 71: 630-637, 1997.
    • (1997) Int. J. Cancer , vol.71 , pp. 630-637
    • Yue, F.Y.1    Dummer, R.2    Geertsen, R.3    Hofbauer, G.4    Laine, E.5    Manolio, S.6    Burg, G.7
  • 6
    • 0030778631 scopus 로고    scopus 로고
    • Interleukin 10 is expressed in human gliomas in vivo and increases glioma cell proliferation and motility in vitro
    • Huettner, C., Czub, S., Kerkau, S., Roggendorf, W., and Tonn, J. C. Interleukin 10 is expressed in human gliomas in vivo and increases glioma cell proliferation and motility in vitro. Anticancer Res., 17: 3217-3224, 1997.
    • (1997) Anticancer Res. , vol.17 , pp. 3217-3224
    • Huettner, C.1    Czub, S.2    Kerkau, S.3    Roggendorf, W.4    Tonn, J.C.5
  • 7
    • 0033994349 scopus 로고    scopus 로고
    • Serum IL-10 levels as a prognostic factor in advanced non-small cell lung cancer patients
    • De Vita, F., Orditura, M., Galizia, G., Romano, C., Roscigno, A., Lieto, E., and Catalano, G. Serum IL-10 levels as a prognostic factor in advanced non-small cell lung cancer patients. Chest, 117: 365-373, 2000.
    • (2000) Chest , vol.117 , pp. 365-373
    • De Vita, F.1    Orditura, M.2    Galizia, G.3    Romano, C.4    Roscigno, A.5    Lieto, E.6    Catalano, G.7
  • 9
    • 0029671316 scopus 로고    scopus 로고
    • TGF-β contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice
    • Maeda, H., and Shiraishi, A. TGF-β contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice. J. Immunol., 156: 73-78, 1996.
    • (1996) J. Immunol. , vol.156 , pp. 73-78
    • Maeda, H.1    Shiraishi, A.2
  • 12
    • 0036173389 scopus 로고    scopus 로고
    • Interleukin-10 promotes B16-melanoma growth by inhibition of macrophage functions and induction of tumor and vascular cell proliferation
    • Garcia-Hernandez, M. L., Hernandez-Pando, R., Gariglio, P., and Berumen, J. Interleukin-10 promotes B16-melanoma growth by inhibition of macrophage functions and induction of tumor and vascular cell proliferation. Immunology, 105: 231-243, 2002.
    • (2002) Immunology , vol.105 , pp. 231-243
    • Garcia-Hernandez, M.L.1    Hernandez-Pando, R.2    Gariglio, P.3    Berumen, J.4
  • 13
    • 0029118395 scopus 로고
    • IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STATIα and STAT3 complexes in human T cells and monocytes
    • Finbloom, D. S., and Winestock, K. D. IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STATIα and STAT3 complexes in human T cells and monocytes. J. Immunol., 155: 1079-1079, 1995.
    • (1995) J. Immunol. , vol.155 , pp. 1079-1079
    • Finbloom, D.S.1    Winestock, K.D.2
  • 14
    • 0036251154 scopus 로고    scopus 로고
    • Stat proteins and oncogenesis
    • Bromberg, J. Stat proteins and oncogenesis. J. Clin. Investig., 109: 1139-1142, 2002.
    • (2002) J. Clin. Investig. , vol.109 , pp. 1139-1142
    • Bromberg, J.1
  • 15
    • 0031569382 scopus 로고    scopus 로고
    • The immunomodulator AS101 inhibits IL-10 release and augments TNF α release by mouse and human mononuclear phagocytes
    • Strassmann, G., Kambayashi, T., Jacob, C. O., and Sredni, D. The immunomodulator AS101 inhibits IL-10 release and augments TNF α release by mouse and human mononuclear phagocytes. Cell. Immunol., 176: 180-185, 1997.
    • (1997) Cell. Immunol. , vol.176 , pp. 180-185
    • Strassmann, G.1    Kambayashi, T.2    Jacob, C.O.3    Sredni, D.4
  • 17
    • 0028905535 scopus 로고
    • Role of endogenous cytokine secretion in radioprotection conferred by the immunomodulator ammonium trichloro(dioxyethylene-o,o′)tellurate
    • Kalechman, Y., Zuloff, A., Albeck, M., Strassmann, G., and Sredni, B. Role of endogenous cytokine secretion in radioprotection conferred by the immunomodulator ammonium trichloro(dioxyethylene-o,o′)tellurate. Blood, 85: 1555-156, 1995.
    • (1995) Blood , vol.85 , pp. 1555-1156
    • Kalechman, Y.1    Zuloff, A.2    Albeck, M.3    Strassmann, G.4    Sredni, B.5
  • 18
    • 0037373243 scopus 로고    scopus 로고
    • Production of the novel mesangial autocrine growth factors GDNF and IL-10 is regulated by the immunomodulator AS101: Role in experimental mesangial proliferative glomerulonephritis
    • Kalechman, Y., Sredni, B., Weinstein, T., Freidkin, I., Tobar, A., Albeck, M., and Gafter, U. Production of the novel mesangial autocrine growth factors GDNF and IL-10 is regulated by the immunomodulator AS101: role in experimental mesangial proliferative glomerulonephritis. J. Am. Soc. Nephrol., 14: 620-630, 2003.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 620-630
    • Kalechman, Y.1    Sredni, B.2    Weinstein, T.3    Freidkin, I.4    Tobar, A.5    Albeck, M.6    Gafter, U.7
  • 20
    • 0031571886 scopus 로고    scopus 로고
    • Delay in the onset of systemic lupus erythematosus following treatment with the immunomodulator AS101: Association with IL-10 inhibition and increase in TNFα levels
    • Kalechman, Y., Gafter, U., Da, J. P., Albeck, M., Alarcon-Segovia, D., and Sredni, B. Delay in the onset of systemic lupus erythematosus following treatment with the immunomodulator AS101: association with IL-10 inhibition and increase in TNFα levels. J. Immunol., 159: 2658-2667, 1997.
    • (1997) J. Immunol. , vol.159 , pp. 2658-2667
    • Kalechman, Y.1    Gafter, U.2    Da, J.P.3    Albeck, M.4    Alarcon-Segovia, D.5    Sredni, B.6
  • 21
    • 0036644330 scopus 로고    scopus 로고
    • Anti IL-10 therapeutic strategy using the immunomodulator AS101 in protecting mice from sepsis-induced death: Dependence on timing of immunomodulating intervention
    • Kalechman, Y., Gafter, U., Gal, R., Rushkin, G., Yan, D., Albeck, M., and Sredni, B. Anti IL-10 therapeutic strategy using the immunomodulator AS101 in protecting mice from sepsis-induced death: dependence on timing of immunomodulating intervention. J. Immunol., 169: 384-392, 2002.
    • (2002) J. Immunol. , vol.169 , pp. 384-392
    • Kalechman, Y.1    Gafter, U.2    Gal, R.3    Rushkin, G.4    Yan, D.5    Albeck, M.6    Sredni, B.7
  • 23
    • 0034087470 scopus 로고    scopus 로고
    • Synergistic anti-tumoral effect of Taxol + AS101 in a murine model of B16 melanoma: Association with ras-dependent signal-transduction pathways
    • Kalechman, Y., Longo, D. L., Catane, R., Shani, A., Albeck, M., and Sredni, B. Synergistic anti-tumoral effect of Taxol + AS101 in a murine model of B16 melanoma: association with ras-dependent signal-transduction pathways. Int. J. Cancer, 86: 281-288, 2000.
    • (2000) Int. J. Cancer , vol.86 , pp. 281-288
    • Kalechman, Y.1    Longo, D.L.2    Catane, R.3    Shani, A.4    Albeck, M.5    Sredni, B.6
  • 24
    • 0027137937 scopus 로고
    • The protective role of AS101 in combination with several cytotoxic drugs acting by different mechanisms of action
    • Kalechman, Y., Sotnik-Barkai, I., Albeck, M., and Sredni, B. The protective role of AS101 in combination with several cytotoxic drugs acting by different mechanisms of action. Cancer Res., 53: 5962-5969, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 5962-5969
    • Kalechman, Y.1    Sotnik-Barkai, I.2    Albeck, M.3    Sredni, B.4
  • 25
    • 0029128406 scopus 로고
    • Kalechman. Y. Bone marrow sparing and prevention of alopecia by AS101 in NSCL cancer patients treated with carboplatin and etoposide
    • Sredni, B., Albeck, M., Tichler, T., Shani, A., Shapira, J., Bruderman, I., Catane, R., Kaufman, B., and Kalechman. Y. Bone marrow sparing and prevention of alopecia by AS101 in NSCL cancer patients treated with carboplatin and etoposide. J. Clin. Oncol., 13: 2342-2353, 1995.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 2342-2353
    • Sredni, B.1    Albeck, M.2    Tichler, T.3    Shani, A.4    Shapira, J.5    Bruderman, I.6    Catane, R.7    Kaufman, B.8
  • 26
    • 0035073292 scopus 로고    scopus 로고
    • Phosphorylation of Bcl-2 and regulation of apoptosis
    • Ruvolo, P. P., Deng, X., and May, W. S. Phosphorylation of Bcl-2 and regulation of apoptosis. Leukemia, 15: 515-522, 2001.
    • (2001) Leukemia , vol.15 , pp. 515-522
    • Ruvolo, P.P.1    Deng, X.2    May, W.S.3
  • 27
    • 0034085912 scopus 로고    scopus 로고
    • Latchman. D. S. Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters
    • Stephanou, A., Brar, B. K., Knight, R. A., and Latchman. D. S. Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters. Cell Death Differ., 7: 329-330, 2000.
    • (2000) Cell Death Differ. , vol.7 , pp. 329-330
    • Stephanou, A.1    Brar, B.K.2    Knight, R.A.3
  • 28
    • 0029166912 scopus 로고
    • Salvage chemotherapy with paclitaxel for recurrent primary brain tumors
    • Chamberlain, M. C., and Kormanik, P. Salvage chemotherapy with paclitaxel for recurrent primary brain tumors. J. Clin. Oncol., 13: 2066-2071, 1995.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 2066-2071
    • Chamberlain, M.C.1    Kormanik, P.2
  • 32
    • 0032481383 scopus 로고    scopus 로고
    • IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: Evidence for Stat3-dependent and independent pathways
    • O'Farrell, A., Liu, Y., Moore, K. W., and Mui, L. IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and independent pathways. EMBO J., 17: 1006-1018, 1998.
    • (1998) EMBO J. , vol.17 , pp. 1006-1018
    • O'Farrell, A.1    Liu, Y.2    Moore, K.W.3    Mui, L.4
  • 33
    • 0033061032 scopus 로고    scopus 로고
    • Protein tyrosine kinase inhibitors as novel therapeutic agents
    • Levitzki, A. Protein tyrosine kinase inhibitors as novel therapeutic agents. Pharmacol. Ther., 82: 231-239, 1999.
    • (1999) Pharmacol. Ther. , vol.82 , pp. 231-239
    • Levitzki, A.1
  • 34
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner, R., Mora, L. B., and Jove, R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin. Cancer Res., 8: 945-954, 2002.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 36
    • 0032193698 scopus 로고    scopus 로고
    • Up-regulation by ammonium trichloro(dioxoethylene-o,o[primes])tellurate (AS101) of Fas/Apo-1 expression on B16 melanoma cells: Implications for the antitumor effects of AS101
    • Kalechman, Y., Strassmann, G., Albeck, M., and Sredni, B. Up-regulation by ammonium trichloro(dioxoethylene-o,o[primes])tellurate (AS101) of Fas/Apo-1 expression on B16 melanoma cells: implications for the antitumor effects of AS101. J. Immunol., 161: 3536-3542, 1998.
    • (1998) J. Immunol. , vol.161 , pp. 3536-3542
    • Kalechman, Y.1    Strassmann, G.2    Albeck, M.3    Sredni, B.4
  • 37
    • 0030874781 scopus 로고    scopus 로고
    • Interleukin-10 rescues T cells from apoptotic cell death: Association with upregulation of Bcl-2
    • Cohen, S. B. A., Crawley, J. B., Kahan, M. C., Feldmann, M., and Foxwell, B. M. Interleukin-10 rescues T cells from apoptotic cell death: association with upregulation of Bcl-2. Immunology, 92: 1-5, 1997.
    • (1997) Immunology , vol.92 , pp. 1-5
    • Cohen, S.B.A.1    Crawley, J.B.2    Kahan, M.C.3    Feldmann, M.4    Foxwell, B.M.5
  • 38
    • 0035393595 scopus 로고    scopus 로고
    • Rituximab inactivates signal transducer and activation of transcription 3 (stat3) activity in B-non-Hodgkin's lymphoma through inhibition of the interleukin 10 autocrine/paracrine loop and results in down-regulation of bcl-2 and sensitization to cytotoxic drugs
    • Alas, S., and Bonavida, B. Rituximab inactivates signal transducer and activation of transcription 3 (stat3) activity in B-non-Hodgkin's lymphoma through inhibition of the interleukin 10 autocrine/paracrine loop and results in down-regulation of bcl-2 and sensitization to cytotoxic drugs. Cancer Res., 61: 5137-5144, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 5137-5144
    • Alas, S.1    Bonavida, B.2
  • 39
    • 0033094311 scopus 로고    scopus 로고
    • Prognostic significance of Bcl-2, Bcl-xLS, Bax and Bak expressions in colorectal carcinomas
    • Ogura, E., Senzaki, H., Yamamoto, D., Yoshida, R., Takada, H., Hioki, K., and Tsubura, A. Prognostic significance of Bcl-2, Bcl-xLS, Bax and Bak expressions in colorectal carcinomas. Oncol. Rep., 6: 365-369, 1999.
    • (1999) Oncol. Rep. , vol.6 , pp. 365-369
    • Ogura, E.1    Senzaki, H.2    Yamamoto, D.3    Yoshida, R.4    Takada, H.5    Hioki, K.6    Tsubura, A.7
  • 41
    • 0035870249 scopus 로고    scopus 로고
    • Overexpression of a dominant negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest
    • Niu, G., Shain, K. H., Huang, M., Ravi, R., Bedi, A., Dalton, W. S., Jove, R., and Yu, H. Overexpression of a dominant negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest. Cancer Res., 61: 3276-3280, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 3276-3280
    • Niu, G.1    Shain, K.H.2    Huang, M.3    Ravi, R.4    Bedi, A.5    Dalton, W.S.6    Jove, R.7    Yu, H.8
  • 42
    • 0028919356 scopus 로고
    • In vitro assessment of Taxol for human glioblastoma: Chemosensitivity and cellular locomotion
    • Silbergeld, D. L., Chicoine, M. R., and Madsen, C. L. In vitro assessment of Taxol for human glioblastoma: chemosensitivity and cellular locomotion. Anticancer Drug, 6: 270-276, 1995.
    • (1995) Anticancer Drug , vol.6 , pp. 270-276
    • Silbergeld, D.L.1    Chicoine, M.R.2    Madsen, C.L.3
  • 43
    • 0033635825 scopus 로고    scopus 로고
    • Treatment of recurrent glioblastoma multiforme using fractionated stereotactic radiosurgery and concurrent paclitaxel
    • Lederman, G., Wronski, M., Arbit, E., Odaimi, M., Wertheim, S., Lombardi, E., and Wrzolek, M. Treatment of recurrent glioblastoma multiforme using fractionated stereotactic radiosurgery and concurrent paclitaxel. Am. J. Clin. Oncol., 23: 155-159, 2000.
    • (2000) Am. J. Clin. Oncol. , vol.23 , pp. 155-159
    • Lederman, G.1    Wronski, M.2    Arbit, E.3    Odaimi, M.4    Wertheim, S.5    Lombardi, E.6    Wrzolek, M.7
  • 44
    • 0031467457 scopus 로고    scopus 로고
    • Expression of Bax and bcl-2 proteins, regulators of programmed cell death, in human brain tumors
    • Hara, A., Hirose, Y., Yoshimi, N., Tanaka, T., and Mori. H. Expression of Bax and bcl-2 proteins, regulators of programmed cell death, in human brain tumors. Neurol. Res., 19: 623-628, 1997.
    • (1997) Neurol. Res. , vol.19 , pp. 623-628
    • Hara, A.1    Hirose, Y.2    Yoshimi, N.3    Tanaka, T.4    Mori, H.5
  • 45
    • 0034068054 scopus 로고    scopus 로고
    • Antisense-mediated inhibition of the bcl-2 gene induces apoptosis in human malignant glioma
    • Julien, T., Frankel, B., Longo, S., Kyle, M., Gibson, S., Shillitoe, E., and Ryken, T. Antisense-mediated inhibition of the bcl-2 gene induces apoptosis in human malignant glioma. Surg. Neurol., 53: 360-369, 2000.
    • (2000) Surg. Neurol. , vol.53 , pp. 360-369
    • Julien, T.1    Frankel, B.2    Longo, S.3    Kyle, M.4    Gibson, S.5    Shillitoe, E.6    Ryken, T.7
  • 47
    • 0027959417 scopus 로고
    • Interleukin 10 pretreatment protects target cells from tumor- and allo-specific cytotoxic T cells and downregulates HLA class I expression
    • Matsuda, M., Salazar, F., Petersson, M., Masucci, G., Hansson, J., Pisa, P., Zhang, Q. J., Masucci, M. G., and Kiessling, R. Interleukin 10 pretreatment protects target cells from tumor- and allo-specific cytotoxic T cells and downregulates HLA class I expression. J. Exp. Med., 180: 2371-2376, 1994.
    • (1994) J. Exp. Med. , vol.180 , pp. 2371-2376
    • Matsuda, M.1    Salazar, F.2    Petersson, M.3    Masucci, G.4    Hansson, J.5    Pisa, P.6    Zhang, Q.J.7    Masucci, M.G.8    Kiessling, R.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.