Transgenic triadin 1 overexpression alters SR Ca2+ handling and leads to a blunted contractile response to β-adrenergic agonists

Cardiovascular Research

Volumn 62, Issue 1, 2004, Pages 122-134

  Kirchhefer, Uwe ^a   Jones, Larry R ^b   Begrow, Frank ^a   Boknik, Peter ^a   Hein, Lutz ^c   Lohse, Martin J ^c   Riemann, Burkhard ^a   Schmitz, Wilhelm ^a   Stypmann, Jörg ^a   Neumann, Joachim ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

BAPTA; Calcium (cellular); Contractile function; e c Coupling; EGTA; Ethylene glycol bis( aminoethyl ether) N,N,N , N tetraacetic acid; Protein phosphorylation; SR (function)

Indexed keywords

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CAFFEINE; CALCIUM CHANNEL L TYPE; CALCIUM ION; CALSEQUESTRIN; PROTEIN KINASE; RECEPTOR PROTEIN; RYANODINE RECEPTOR; TRIADIN 1; UNCLASSIFIED DRUG;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; ECHOCARDIOGRAPHY; EXCITATION CONTRACTION COUPLING; HEART CATHETERIZATION; HEART FUNCTION; HEART LEFT VENTRICLE CONTRACTILITY; HEART LEFT VENTRICLE CONTRACTION; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SARCOPLASMIC RETICULUM; STRAIN DIFFERENCE; TRANSGENIC MOUSE; WILD TYPE;

ADRENERGIC BETA-AGONISTS; ANIMALS; CAFFEINE; CALCIUM; CARRIER PROTEINS; ECHOCARDIOGRAPHY, DOPPLER; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; MICE; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; MUSCLE PROTEINS; MYOCARDIAL CONTRACTION; PHOSPHORYLATION; SARCOPLASMIC RETICULUM;

EID: 12144289713     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2004.01.005     Document Type: Article

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