Impaired relaxation in transgenic mice overexpressing junctin

Cardiovascular Research

Volumn 59, Issue 2, 2003, Pages 369-379

  Kirchhefer, Uwe ^a   Neumann, Joachim ^a   Bers, Donald M ^b   Buchwalow, Igor B ^c   Fabritz, Larissa ^a   Hanske, Gabriela ^a   Justus, Isabel ^a   Riemann, Burkhard ^a   Schmitz, Wilhelm ^a   Jones, Larry R ^d  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium (cellular); Contractile function; E contraction coupling; Hypertrophy; SR (function)

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); BARIUM; CAFFEINE; CALCIUM CHANNEL L TYPE; CALCIUM ION; CALSEQUESTRIN; JUNCTIN; MEMBRANE PROTEIN; PHOSPHOLAMBAN; PROTEIN; RYANODINE RECEPTOR; TRIADIN; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; ELECTRICITY; ELECTROSTIMULATION; EXCITATION CONTRACTION COUPLING; HEART HYPERTROPHY; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE RELAXATION; HEART VENTRICLE; ISOLATED HEART; KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SARCOPLASMIC RETICULUM; TRANSGENIC MOUSE;

NON-PROGRAMMATIC;

ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM-BINDING PROTEINS; CARDIOMEGALY; CARRIER PROTEINS; CELL SIZE; ECHOCARDIOGRAPHY, DOPPLER; ELECTRIC STIMULATION; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MIXED FUNCTION OXYGENASES; MUSCLE PROTEINS; MUSCLE RELAXATION; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PAPILLARY MUSCLES; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

EID: 10744228510     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(03)00432-2     Document Type: Article

References (41)

1. Fabiato A., Fabiato F. Contractions induced by a calcium-triggered release of calcium from the sarcoplasmic reticulum of single skinned cardiac cells. J Physiol. 249:1975;469-495.
2. 2+ channels and ryanodine receptors in cardiac myocytes. Proc Natl Acad Sci USA. 92:1995;121-125.
3. Bers D.M. Excitation-contraction coupling and cardiac contractile force. 2001;Kluwer, Boston, MA.
4. Kiriazis H., Kranias E.G. Genetically engineered models with alterations in cardiac membrane calcium-handling proteins. Annu Rev Physiol. 62:2000;321-351.
5. Wagenknecht T., Grassucci R., Frank J., et al. Three-dimensional architecture of the calcium channel/foot structure of sarcoplasmic reticulum. Nature. 338:1989;167-170.
6. Campbell K.P., MacLennan D.H., Jorgensen A.O., Mintzer M.C. Purification and characterization of calsequestrin from canine cardiac sarcoplasmic reticulum and identification of the 53,000 dalton glycoprotein. J Biol Chem. 258:1983;1197-1204.
7. Ikemoto N., Ronjat M., Meszaros L.G., Koshita M. Postulated role of calsequestrin in the regulation of calcium release from sarcoplasmic reticulum. Biochemistry. 28:1989;6764-6771.
8. 2+ and interacts with triadin. FEBS Lett. 486:2000;178-182.
9. Zhang L., Kelly J., Schmeisser G., Kobayashi Y.M., Jones L.R. Complex formation between junctin, triadin, calsequestrin, and the ryanodine receptor. J Biol Chem. 272:1997;23389-23397.
10. Jones L.R., Zhang L., Sanborn K., Jorgensen A.O., Kelley J. Purification, primary structure, and immunological characterization of the 26-kDa calsequestrin binding protein (junctin) from cardiac junctional sarcoplasmic reticulum. J Biol Chem. 270:1995;30787-30796.
11. Kawasaki T., Kasai M. Regulation of calcium channel in sarcoplasmic reticulum by calsequestrin. Biochem Biophys Res Commun. 199:1994;1120-1127.
12. Yamaguchi N., Kawasaki T., Kasai M. DIDS binding 30-kDa protein regulates the calcium release channel in the sarcoplasmic reticulum. Biochem Biophys Res Commun. 210:1995;648-653.
13. Kagari T., Yamaguchi N., Kasai M. Biochemical characterization of calsequestrin-binding 30-kDa protein in sarcoplasmic reticulum of skeletal muscle. Biochem Biophys Res Commun. 227:1996;700-706.
14. Guo W., Campbell K.P. Association of triadin with the ryanodine receptor and calsequestrin in the lumen of the sarcoplasmic reticulum. J Biol Chem. 270:1995;9027-9030.
15. Kobayashi Y.M., Jones L.R. Identification of triadin 1 as the predominant triadin isoform expressed in mammalian myocardium. J Biol Chem. 274:1999;28660-28668.
16. Kobayashi Y.M., Alseikhan B.A., Jones L.R. Localization and characterization of the calsequestrin-binding domain of triadin 1. Evidence for a charged beta-strand in mediating the protein-protein interaction. J Biol Chem. 275:2000;17639-17646.
17. Dinchuk J.E., Henderson N.L., Burn T.C., et al. Aspartyl β-hydroxylase (Asph) and an evolutionarily conserved isoform of Asph missing the catalytic domain share exons with junctin. J Biol Chem. 275:2000;39543-39554.
18. Ohkura M., Furukawa K.I., Fujimori H., et al. Dual regulation of the skeletal muscle ryanodine receptor by triadin and calsequestrin. Biochemistry. 37:1998;12987-12993.
19. 2+-release channel activity of the skeletal-muscle ryanodine receptor by an indirect mechanism. Biochem J. 339:1999;343-350.
20. Kirchhefer U., Neumann J., Baba H.A., et al. Cardiac hypertrophy and impaired relaxation in transgenic mice overexpressing triadin 1. J Biol Chem. 276:2001;4142-4149.
21. Kirchhefer U., Baba H.A., Kobayashi Y.M., et al. Altered function in atrium of transgenic mice overexpressing triadin 1. Am J Physiol. 283:2002;H1334-H1343.
22. Zhang L., Franzini-Armstrong C., Ramesh V., Jones L.R. Structural alterations in cardiac calcium release units resulting from overexpression of junctin. J Mol Cell Cardiol. 33:2001;233-247.
23. Hogan B., Constantini F., Lacy E. Manipulating the mouse embryo: a laboratory manual. 1986;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
24. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:1987;156-159.
25. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J Biol Chem. 193:1951;265-275.
26. Porzio M.A., Pearson A.M. Improved resolution of myofibrillar proteins with sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochim Biophys Acta. 490:1977;27-34.
27. Mahony L., Jones L.R. Developmental changes in cardiac sarcoplasmic reticulum in sheep. J Biol Chem. 261:1986;15257-15265.
28. 2+ transport ATPase of cardiac sarcoplasmic reticulum. J Biol Chem. 259:1993;1834-1841.
29. Scatchard G. The attraction of proteins for small molecules and ions. Ann NY Acad Sci. 51:1949;660-672.
30. Boknik P., Neumann J., Kaspareit G., et al. Mechanisms of the contractile effects of levosimendan in the mammalian heart. J Pharmacol Exp Ther. 280:1997;277-283.
31. Gulick J., Subramaniam A., Neumann J., Robbins J. Isolation and characterization of the mouse cardiac myosin heavy chain genes. J Biol Chem. 266:1991;9180-9185.
32. 2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin. J Clin Invest. 101:1998;1385-1393.
33. Hu K.Y., Huso D.L., Dawson T.M., Bredt D.S., Becker L.C. Nitric oxide synthase in cardiac sarcoplasmic reticulum. Proc Natl Acad Sci USA. 96:1999;657-662.
34. Buchwalow I.B., Schulze W., Karczewski P., et al. Inducible nitric oxide synthase in the myocard. Mol Cell Biochem. 217:2001;73-82.
35. 2+ release channels and their regulation by endogenous effectors. Annu Rev Physiol. 56:1994;485-508.
36. 2+ channels in mouse ventricular myocytes. Am J Physiol. 272:1997;H606-H612.
37. Hong C.S., Cho M.C., Kwak Y.G., et al. Cardiac remodeling and atrial fibrillation in transgenic mice overexpressing junctin. FASEB J. 16:2002;1310-1312.
38. Molkentin J.D., Lu J.R., Antos C.L., et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell. 93:1998;215-228.
39. 2+/calmodulin-dependent protein kinase II regulates atrial natriuretic factor gene expression in ventricular myocytes. J Biol Chem. 272:1997;31203-31208.
40. 2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. J Biol Chem. 277:2002;1261-1267.
41. Li L., Chu G., Kranias E.G., Bers D.M. Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects. Am J Physiol. 274:1998;H1335-H1347.