CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding

Biochemistry

Volumn 44, Issue 2, 2005, Pages 490-497

  De Guzman, Roberto N ^a   Wojciak, Jonathan M ^a   Martinez Yamout, Maria A ^a   Dyson, H Jane ^a   Wright, Peter E ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CONCENTRATION (PROCESS); NUCLEAR MAGNETIC RESONANCE; STOICHIOMETRY; TOPOLOGY; ZINC;

CBP; HELIX; PROTEIN-PROTEIN RECOGNITION; TAZ DOMAINS;

PROTEINS;

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; TRANSCRIPTION FACTOR; ZINC;

AMINO ACID SEQUENCE; ARTICLE; CIRCULAR DICHROISM; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE; PARALOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; STOICHIOMETRY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; E1A-ASSOCIATED P300 PROTEIN; HUMANS; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SOLUTIONS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; ZINC;

EID: 12144255152     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048161t     Document Type: Article

References (22)

1. Chrivia, J. C., Kwok, R. P., Lamb, N., Hagiwara, M., Montminy, M., and Goodman, R. H. (1993) Phosphorylated CREB binds specifically to nuclear protein CBP, Nature 365, 855-859.
2. Eckner, R., Ewen, M. E., Newsome, D., Gerdes, M., DeCaprio, J. A., Lawrence, J. B., and Livingston, D. M. (1994) Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor, Genes Devel. 8, 869-884.
3. Ponting, C. P., Blake, D. J., Davies, K. E., Kendrick-Jones, J., and Winder, S. J. (1996) ZZ and TAZ: New putative zinc fingers in dystrophin and other proteins, Trends Biochem. Sci. 21, 11-13.
4. De Guzman, R. N., Liu, H. Y., Martinez-Yamout, M., Dyson, H. J., and Wright, P. E. (2000) Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP, J. Mol. Biol. 303, 243-253.
5. Dames, S. A., Martinez-Yamout, M., De Guzman, R. N., Dyson, H. J., and Wright, P. E. (2002) Structural basis for Hif-1 alpha/CBP recognition in the cellular hypoxic response, Proc. Natl. Acad. Sci. U.S.A 99, 5271-5276.
6. Freedman, S. J., Sun, Z. Y., Poy, F., Kung, A. L., Livingston, D. M., Wagner, G., and Eck, M. J. (2002) Structural basis for recruitment of CBP/ p300 by hypoxia-inducible factor-1alpha, Proc. Natl. Acad. Sci. U.S.A. 99, 5367-5372.
7. Freedman, S. J., Sun, Z. Y., Kung, A. L., France, D. S., Wagner, G., and Eck, M. J. (2003) Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2, Nat. Struct. Biol. 10, 504-512.
8. De Guzman, R. N., Martinez-Yamout, M., Dyson, H. J., and Wright, P. E. (2004) Interaction of the TAZ1 Domain of CREB-Binding Protein with the Activation Domain of CITED2: Regulation by Competition between Intrinsically Unstructured Ligands for Non-Identical Binding Sites, J. Biol. Chem. 279, 3042-3049.
9. Dial, R., Sun, Z. Y., and Freedman, S. J. (2003) Three conformational states of the p300 CH1 domain define its functional properties, Biochemistry 42, 9937-9945.
10. Delaglio, F., Grzesiek, S., Vuister, G. W., Guang, Z., Pfeifer, J., and Bax, A. (1995) NMRPipe: A multidimensional spectral processing system based on UNIX pipes, J. Biomol. NMR 6, 277-293.
11. Johnson, B. A. and Blevins, R. A. (1994) NMRView: A computer program for the visualization and analysis of NMR data, J. Biomol. NMR 4, 604-613.
12. Bax, A., Vuister, G. W., Grzesiek, S., Delaglio, F., Wang, A. C., Tschudin, R., and Zhu, G. (1994) Measurement of homo- and heteronuclear J-couplings from quantitative J correlation, Methods Enzymol. 239, 79-105.
13. Wishart, D. S., and Nip, A. M. (1998) Protein chemical shift analysis: A practical guide, Biochem. Cell Biol. 76, 153-163.
14. Wüthrich, K. (1986) NMR of Proteins and Nucleic Acids, John Wiley and Sons, New York, N. Y.
15. Duggan, B. M., Legge, G. B., Dyson, H. J., and Wright, P. E. (2001) SANE (Structure assisted NOE evaluation): An automated model-based approach for NOE assignment, J. Biomol. NMR 19, 321-329.
16. Güntert, P., Mumenthaler, C., and Wüthrich, K. (1997) Torsion angle dynamics for NMR structure calculation with the new program DYANA, J. Mol. Biol. 273, 283-298.
17. Case, D. A., Pearlman, D. A., Caldwell, J. W., Cheatham, T. E., III, Wang, J., Ross, W. S., Simmerling, C. L., Darden, T. A., Merz, K. M., Stanton, R. V., Cheng, A. L., Vincent, J. J., Crowley, M., Tsui, V., Gohlke, H., Radmer, R. J., Duan, Y., Pitera, J., Massova, I., Seibel, G. L., Singh, U. C., Weiner, P. K., and Kollman, P. A. (2002) AMBER 7, University of California, San Francisco, CA.
18. Tsui, V. and Case, D. A. (2000) Molecular simulations of nucleic acids using a generalized Born solvation model, J. Am. Chem. Soc. 122, 2489-2498.
19. Laskowski, R. A., Rullmann, J. A. C., MacArthur, M. W., Kaptein, R., and Thornton, J. M. (1996) AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR, J. Biomol. NMR 8, 477-486.
20. Koradi, R., Billeter, M., and Wüthrich, K. (1996) MOLMOL: A program for display and analysis of macromolecular structures, J. Mol. Graphics 14, 51-55.
21. Demarest, S. J., Martinez-Yamout, M., Chung, J., Chen, H., Xu, W., Dyson, H. J., Evans, R. M., and Wright, P. E. (2002) Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators, Nature 415, 549-553.
22. Radhakrishnan, I., Pérez-Alvarado, G. C., Parker, D., Dyson, H. J., Montminy, M. R., and Wright, P. E. (1997) Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: A model for activator:coactivator interactions, Cell 91, 741-752.