Picolinic acids as inhibitors of dopamine β-monooxygenase: QSAR and putative binding site

Archiv der Pharmazie

Volumn 337, Issue 12, 2004, Pages 645-653

  Dove, Stefan ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Dopamine Monooxygenase Binding Site; Dopamine Monooxygenase Inhibitors; Picolinic Acids; QSAR

Indexed keywords

CARBOXYLIC ACID; COPPER; DOPAMINE; DOPAMINE BETA MONOOXYGENASE; FUSARIC ACID; ISOLEUCINE; OXYGENASE; PEPTIDYLGLYCINE ALPHA HYDROXYLATING MONOOXYGENASE; PICOLINIC ACID DERIVATIVE; TYROSINE; UNCLASSIFIED DRUG;

ADRENAL MEDULLA; ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COW; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; ELECTROCHEMISTRY; ENZYME INHIBITION; HYDROPHOBICITY; LIPOPHILICITY; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REFRACTOMETRY; STEREOCHEMISTRY;

ADRENAL MEDULLA; ANIMALS; BINDING SITES; CATTLE; DOPAMINE BETA-HYDROXYLASE; ENZYME INHIBITORS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PICOLINIC ACIDS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 11944262606     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.200400619     Document Type: Article

References (23)

1. S. T. Prigge, A. S. Kolhekar, B. A. Eipper, R. E. Mains, L. M. Amzel, Science 1997, 278, 1300-1305.
2. S. T. Prigge, A. S. Kolhekar, B. A. Eipper, R. E. Mains, L. M. Amzel, Nat. Struct. Biol. 1999, 6, 976-983.
3. S. T. Prigge, R. E. Mains, B. A. Eipper, L. M. Amzel, Cell. Mol. Life Sci. 2000, 57, 1236-1259.
4. S. T. Prigge, B. A. Eipper, R. E. Mains, L. M. Amzel, Science 2004, 304, 864-867.
5. J. C. Freeman, J. J. Villafranca, D. J. Merkler, J. Am. Chem. Soc. 1993, 115, 4923-4924.
6. J. P. Evans, K. Ahn, J. P. Klinman, J. Biol. Chem. 2003, 278, 49691-49698.
7. L. C. Stewart, J. P. Klinman, J. Biol. Chem. 1991, 266, 11537-11543.
8. M. C. Brenner, J. P. Klinman, Biochemistry 1989, 28, 4664-4670.
9. H. Hidaka, Nature 1971, 231, 54-55.
10. T. Nagatsu, H. Hidaka, H. Kuzuya, K. Takeya, H. Umezawa, Biochem. Pharmacol. 1970, 19, 35-44.
11. L. Piesche, H. Hilse, J. Oehlke, E. Schrotter, P. Oehme, Pharmazie 1983, 38, 335-338.
12. H. Hidaka, T. Asano, N. Takemoto, Mol. Pharmacol. 1973, 9, 172-177.
13. H. Suda, T. Takeuchi, T. Nagatsu, M. Matsuzaki, I. Matsumoto, H. Umezawa, Chem. Pharm. Bull. (Tokyo) 1969, 17, 2377-2380.
14. K. Miyano, T. Sakasai, H. Hamano, Chem. Pharm. Bull. (Tokyo) 1978, 26, 2328-2333.
15. L. Piesche, H. Hilse, P. Oehme, Pharmazie 1979, 34, 332-334.
16. stTelesymposium on Medicinal Chemistry (Ed. M. Kuchar), J. R. Prous Publishers, Barcelona, 1984, pp. 117-134.
17. A. Klamt, G. Shuermann, J. Chem. Soc., Perkin Trans. 1993, 2, 799-805.
18. R. Todeschini, V. Consonni, Handbook of Molecular Descriptors, Vol. 11, Wiley-VCH, Weinheim, 2000.
19. R. D. Cramer III, D. E. Patterson, J. D. Bunce, J. Am. Chem. Soc. 1988, 110, 5959-5967.
20. F. Franks, in Water, a comprehensive treatise, Vol. 4 (Ed. F. Franks), Plenum Press, New York, 1975, pp. 1-94.
21. T. Ljones, T. Skotland, T. Flatmark, Eur. J. Biochem. 1976, 61, 525-533.
22. C. Hansch, A. Leo, D. Hoekman, Exploring QSAR - Hydrophobic, Electronic, and Steric Constants, Vol. 2, American Chemical Society, Washington, DC, 1995.
23. M. J. S. Dewar, E. G. Zoebisch, E. F. Healy, J. J. P. Stewart, J. Am. Chem. Soc. 1985, 107, 3902-3909.