A concise synthesis of a novel antiangiogenic tyrosine kinase inhibitor

Journal of Organic Chemistry

Volumn 70, Issue 1, 2005, Pages 175-178

  Payack, Joseph F ^a   Vazquez, Enrique ^a   Matty, Louis ^a   Kress, Michael H ^a   McNamara, James ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AROMATIC COMPOUNDS; CRYOGENICS; ENZYMES;

BORONATION; EFFICIENT SYNTHESIS; KINASE; SUZUKI COUPLING;

SYNTHESIS (CHEMICAL);

3 [5 [[4 (METHYSULFONYL) 1 PIPERAZINYL] METHYL] 1H INDOL 2 YL]QUINOLIN 2(1H) ONE; ANGIOGENESIS INHIBITOR; BORONIC ACID DERIVATIVE; BROMIDE; INDOLE; UNCLASSIFIED DRUG; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR 2;

ARTICLE; CHEMICAL MODIFICATION; DEPROTECTION REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STRUCTURE ANALYSIS; SUZUKI REACTION;

ANGIOGENESIS INHIBITORS; CATALYSIS; INDICATORS AND REAGENTS; INDOLES; MOLECULAR STRUCTURE; PIPERAZINES; PROTEIN-TYROSINE KINASES;

EID: 11844301268     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo048334k     Document Type: Article

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