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N. Geldner, N. Anders, H. Wolters, J. Keicher, W. Kornberger, P. Müller, A. Delbarre, T. Ueda, A. Nakano, and G. Jürgens The Arabidopsis GNOM ARF-GEF mediates endosomal recycling, auxin transport, and auxin-dependent plant growth Cell 112 2003 219 230 By rendering the GN ARF-GEF resistant to the fungal toxin Brefeldin A, the authors provide strong evidence that the auxin-related effects of the drug are mediated through GN. Results described in this paper, together with subcellular localization of GN to endosomes, provide convincing evidence that GN regulates auxin efflux by promoting the recycling of PIN1 from endosomes to the plasma membrane.
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H. Hellmann, L. Hobbie, A. Chapman, S. Dharmasiri, N. Dharmasiri, C. del Pozo, D. Reinhardt, and M. Estelle Arabidopsis AXR6 encodes CUL1 implicating SCF E3 ligases in auxin regulation of embryogenesis EMBO J 22 2003 3314 3325 The authors of this paper report the identification of AXR6 as AtCullin1. axr6 mutants show auxin-related postembryonic phenotypes and embryo defects similar to those in mp and bdl. It appears that these phenotypes are probably caused by a failure to selectively degrade proteins, possibly including BDL.
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