Response to 5% carbon dioxide in children and adolescents: Relationship to panic disorder in parents and anxiety disorders in subjects

Archives of General Psychiatry

Volumn 62, Issue 1, 2005, Pages 73-80

  Pine, Daniel S ^a   Klein, Rachel G ^b   Roberson Nay, Roxann ^a   Mannuzza, Salvatore ^b,c   Moulton III, John L ^b   Woldehawariat, Girma ^a   Guardino, Mary ^d  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NEW YORK UNIVERSITY CHILD STUDY CENTER   (United States)

^c NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^d Freedom from Fear   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE;

ADOLESCENT; ADULT; ANXIETY DISORDER; ARTICLE; BREATHING RATE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MARKER; FAMILIAL DISEASE; FEMALE; GENETIC SUSCEPTIBILITY; HUMAN; LUNG VOLUME; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; PANIC; PHOBIA; RATING SCALE; RISK ASSESSMENT; SCHOOL CHILD; SENSITIVITY ANALYSIS; SPIROMETRY; THREAT;

ADOLESCENT; ADULT; AGE FACTORS; ANXIETY DISORDERS; CARBON DIOXIDE; CHILD; CHILD OF IMPAIRED PARENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENETIC MARKERS; HUMANS; PANIC DISORDER; PERSONALITY INVENTORY; PSYCHIATRIC STATUS RATING SCALES; RESPIRATORY PHYSIOLOGY; RISK FACTORS;

EID: 11844271921     PISSN: 0003990X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpsyc.62.1.73     Document Type: Article

References (36)

1. Kent JM, Papp LA, Martinez JM, Browne ST, Coplan JD, Klein DF, Gorman JM. Specificity of panic response to CO(2) inhalation in panic disorder: a comparison with major depression and premenstrual dysphoric disorder. Am J Psychiatry. 2001;158:58-67.
2. Papp LA, Klein DF, Gorman JM. Carbon dioxide hypersensitivity, hyperventilation, and panic disorder. Am J Psychiatry. 1993;150:1149-1157.
3. Sanderson WC, Rapee RM, Barlow DH. The influence of an illusion of control on panic attacks induced via inhalation of 5.5% carbon dioxide-enriched air. Arch Gen Psychiatry. 1989;46:157-162.
4. Klein DF. Panic and phobic anxiety: phenotypes, endophenotypes, and genotypes. Am J Psychiatry. 1998;155:1147-1149.
5. Gorman JM, Fyer MR, Goetz R, Askanazi J, Liebowitz MR, Fyer AJ, Kinney J, Klein DF. Ventilatory physiology of patients with panic disorder. Arch Gen Psychiatry. 1988;45:31-39.
6. Gorman JM, Kent J, Martinez J, Browne S, Coplan J, Papp LA. Physiological changes during carbon dioxide inhalation in patients with panic disorder, major depression, and premenstrual dysphoric disorder: evidence for a central fear mechanism. Arch Gen Psychiatry. 2001;58:125-131.
7. Papp LA, Martinez JM, Klein DF, Coplan JD, Norman RG, Cole R, de Jesus MJ, Ross O, Goetz R, Gorman JM. Respiratory psychophysiology of panic disorder: three respiratory challenges in 98 subjects. Am J Psychiatry. 1997;154:1557-1565.
8. Pain MC, Biddle N, Tiller JW. Panic disorder, the ventilatory response to carbon dioxide and respiratory variables. Psychosom Med. 1988;50:541-548.
9. Sasaki I, Akiyoshi J, Sakurai R, Tsutsumi T, Ono H, Yamada K, Fujii I. Carbon dioxide induced panic attack in panic disorder in Japan. Prog Neuropsychopharmacol Biol Psychiatry. 1996;20:1145-1157.
10. Lousberg H, Griez E, van den Hout MA. Carbon dioxide chemosensitivity in panic disorder. Acta Psychiatr Scand. 1988;77:214-218.
11. Coryell W, Fyer A, Pine D, Martinez J, Arndt S. Aberrant respiratory sensitivity to CO(2) as a trait of familial panic disorder. Biol Psychiatry. 2001;49:582-587.
12. Perna G, Ieva A, Caldirola D, Bertani A, Bellodi L. Respiration in children at risk for panic disorder. Arch Gen Psychiatry. 2002;59:185-186.
13. Perna G, Cocchi S, Bertani A, Arancio C, Bellodi L. Sensitivity to 35% CO2 in healthy first-degree relatives of patients with panic disorder. Am J Psychiatry. 1995;152:623-625.
14. Coryell W. Hypersensitivity to carbon dioxide as a disease-specific trait marker. Biol Psychiatry. 1997;41:259-263.
15. Klein RG, Pine DS. Anxiety disorders. In: Rutter M, Taylor E, Hersov L, eds. Child and Adolescent Psychiatry, 4th Edition. New York, NY: Elsevier; 2002:486-509.
16. Pine DS, Klein RG, Coplan JD, Papp LA, Hoven CW, Martinez J, Kovalenko P, Mandell DJ, Moreau D, Klein DF, Gorman JM. Differential carbon dioxide sensitivity in childhood anxiety disorders and nonill comparison group. Arch Gen Psychiatry. 2000;57:960-967.
17. Pine DS, Coplan JD, Papp LA, Klein RG, Martinez JM, Kovalenko P, Tancer N, Moreau D, Dummit ES III, Shaffer D, Klein DF, Gorman JM. Ventilatory physiology of children and adolescents with anxiety disorders. Arch Gen Psychiatry. 1998;55:123-129.
18. Coplan JD, Moreau D, Chaput F, Martinez JM, Hoven CW, Mandell DJ, Gorman JM, Pine DS. Salivary cortisol concentrations before and after carbon-dioxide inhalations in children. Biol Psychiatry. 2002;51:326-333.
19. Mannuzza S, Fyer AJ, Endicott J, Gallops MS, Martin LY, Reich T, Klein DF. An extension of the acquaintanceship procedure in family studies of mental disorder. J Psychiatr Res. 1992;26:45-57.
20. Spitzer RL, Williams JB, Gibbon M, First MB. The Structured Clinical Interview for DSM-III-R(SCID), I: history, rationale, and description. Arch Gen Psychiatry. 1992;49:624-629.
21. Kentgen LM, Klein RG, Mannuzza S, Davies M. Test-retest reliability of maternal reports of lifetime mental disorders in their children. J Abnorm Child Psychol. 1997;25:389-398.
22. Slattery MJ, Klein DF, Mannuzza S, Moulton JL III, Pine DS, Klein RG. Relationship between separation anxiety disorder, parental panic disorder, and atopic disorders in children: a controlled high-risk study. J Am Acad Child Adolesc Psychiatry. 2002;41:947-954.
23. Caldirola D, Bellodi L, Caumo A, Migliarese G, Perna G. Approximate entropy of respiratory patterns in panic disorder. Am J Psychiatry. 2004;161:79-87.
24. Verbeke G, Molenberghs G. Linear Models in Practice: A SAS-Oriented Approach. New York, NY: Springer; 1997.
25. Rosenbaum JF, Biederman J, Hirshfeld-Becker DR, Kagan J, Snidman N, Friedman D, Nineberg A, Gallery DJ, Faraone SV. A controlled study of behavioral inhibition in children of parents with panic disorder and depression. Am J Psychiatry. 2000;157:2002-2010.
26. Wolfinger R. An example of using mixed models and proc mixed for longitudinal data. J Biopharm Stat. 1997;7:481-500.
27. Littell RC, Milliken GA, Stroup WW, Wofinger RD. SAS System for Mixed Models. Cary, NC: SAS Institute Inc; 1996.
28. Pine DS, Cohen P, Gurley D, Brook J, Ma Y. The risk for early-adulthood anxiety and depressive disorders in adolescents with anxiety and depressive disorders. Arch Gen Psychiatry. 1998;55:56-64.
29. Hollingshead AB, Redlich FC. Social Class and Mental Illness: A Community Study. New York, NY: John Wiley & Sons; 1958.
30. van Beek N, Griez E. Reactivity to a 35% CO2 challenge in healthy first-degree relatives of patients with panic disorder. Biol Psychiatry. 2000;47:830-835.
31. Coryell W, Arndt S. The 35% CO2 inhalation procedure: test-retest reliability. Biol Psychiatry. 1999;45:923-927.
32. Yeragani VK, Radhakrishna RK, Tancer M, Uhde T. Nonlinear measures of respiration: respiratory irregularity and increased chaos of respiration in patients with panic disorder. Neuropsychobiology. 2002;46:111-120.
33. Carter MM, Hollon SD, Carson R, Shelton RC. Effects of a safe person on induced distress following a biological challenge in panic disorder with agoraphobia. J Abnorm Psychol. 1995;104:156-163.
34. Abelson JL, Nesse RM, Weg JG, Curtis GC. Respiratory psychophysiology and anxiety: cognitive intervention in the doxapram model of panic. Psychosom Med. 1996;58:302-313.
35. Merikangas KR, Avenevoli S, Dierker L, Grillon C. Vulnerability factors among children at risk for anxiety disorders. Biol Psychiatry. 1999;46:1523-1535.
36. Weissman MM, Warner V, Wickramaratne P, Moreau D, Olfson M. Offspring of depressed parents: 10 years later. Arch Gen Psychiatry. 1997;54:932-940.