Screening of 12 SNPs of CYP3A4 in a Chinese population using oligonucleotide microarray

Genetic Testing

Volumn 8, Issue 4, 2004, Pages 411-416

  Wen, Siyuan ^a   Wang, Hong ^b   Ding, Yu ^a   Liang, Hao ^a   Wang, Shengqi ^a  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4;

ARTICLE; CHINESE; DNA MICROARRAY; ENZYME ACTIVITY; GENE SEQUENCE; GENETIC SCREENING; GENOTYPE; HETEROZYGOSITY; HUMAN; NUCLEOTIDE SEQUENCE; PLASMID; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

CHINA; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; GENETIC SCREENING; GENOTYPE; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLASMIDS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 11444270948     PISSN: 10906576     EISSN: None     Source Type: Journal    
DOI: 10.1089/gte.2004.8.411     Document Type: Article

References (20)

1. DAI, D., TANG, J., ROSE, R., et al. (2001). Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos. J. Pharmacol. Exp. Ther. 299, 825-831.
2. DAVIDSON, M.H. (2000). Does differing metabolism by cytochrome P450 have clinical importance? Curr. Atheroscler. Rep. 2, 14-19.
3. EISELT, R., DOMANSKI, T.L., ZIBAT, A., et al. (2001). Identification and functional characterization of eight CYP3A4 protein variants. Pharmacogenetics 11, 447-458.
4. GONZALEZ, F.J., and GELBOIN, H.V. (1994). Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins. Drug Metab. Rev. 26, 165.
5. HAMZEIY, H., VAHDATI-MASHHADIAN, N., EDWARD H.J., et al. (2002). Mutation analysis of the human CYP3A4 gene 5' regulatory region: population screening using non radioactive SSCP. Mutat. Res. 20, 103-110.
6. HERSBERGER, M., MARTI-JAUN, J., RENTSCH, K., et al. (2000). Rapid detection of the CYP2D6*3, CYP2D6*4, and CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR. Clin Chem. 46, 1072-1077.
7. HSIEH, K.P., LIN, Y.Y., CHENG, C.L., et al. (2001). Novel mutations of CYP3A4 in Chinese. Drug Metab. Dispos. 29, 268-273.
8. HUBER, M., MUNDLEIN, A., DORNSTAUDER, E., et al. (2002). Accessing single nucleotide polymorphisms in genomic DNA by direct multiplex polymerase chain reaction amplification on oligonucleotide microarrays. Anal. Biochem. 303, 25-33.
9. IWASAKI, H., EZURA, Y., ISHIDA, R., et al. (2002). Accuracy of genotyping for single nucleotide polymorphisms by a microarray-based single nucleotide polymorphism typing method involving hybridization of short allele-specific oligonucleotides. DNA Res. 9, 59-62.
10. KLEIBER, J., WALTER, T., HABERHAUSEN, G., et al. (2000). Performance characteristics of a quantitative, homogeneous TaqMan RT-PCR test for HCV RNA. J. Mol. Diagn. 2, 158-166.
11. KUEHL, P., ZHANG, J., LIN, Y., et al. (2001). Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat. Genet. 27, 383-391.
12. LAMBA, J.K., LIN, Y.S., THUMMEL, K., et al. (2002). Common allelic variants of cytochrome P4503A4 and their prevalence in different populations. Pharmacogenetics 12, 121-132.
13. LI, J.J., GEYER, R., and TAN, W. (2000). Using molecular beacons as a sensitive fluorescence assay for enzymatic cleavage of single-stranded DNA. Nucleic Acids Res. 28, E52.
14. ODA, Y., KOBAYASHI, M., OOI, A., et al. (1999). Genotypes of glutathione S-transferase M1 and N-acetyltransferase 2 in Japanese patients with gastric cancer. Gastric Cancer 2, 158-164.
15. O'MEARA, D., AHMADIAN, A., ODEBERG, J., et al. (2002). SNP typing by apyrase-mediated allele-specific primer extension on DNA microarrays. Nucleic Acids Res. 30, e75.
16. REBBECK, T.R., JAFFE, J.M., WALKER, A.H., et al. (1998). Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. J. Natl. Cancer Inst. 90, 1225-1229.
17. RENDIC, S., and DI CARLO, F.J. (1997). Human cytochrome P450 enzymes: A status report summarizing their reactions, substrates, inducers and inhibitors. Drug Metab. Rev. 29, 413.
18. rd ed. (Cold Spring Harbor Laboratory Press, New York).
19. SATA, F., SAPONE, A., ELIZONDO, G., et al. (2000). CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: Evidence for an allelic variant with altered catalytic activity. Clin. Pharmacol. Ther. 67, 48-56.
20. WEATLIND, A., LOFBERG, L., TINDBERG, N., et al. (1999). Inter individual differences in hepatic expression of CYP3A4: Relationship to genetic polymorphism in 5'-upstream regulatory region. Biochem. Biophys. Res. Commun. 27, 201-205.