Upregulation of functionally active vascular endothelial growth factor by human cytomegalovirus

Journal of General Virology

Volumn 86, Issue 1, 2005, Pages 23-30

  Reinhardt, Barbara ^a   Schaarschmidt, Peter ^b   Bossert, Andrea ^a   Lüke, Anke ^a   Finkenzeller, Günter ^c   Mertens, Thomas ^a   Michel, Detlef ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b ROCHE DIAGNOSTICS GMBH   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; NEUTRALIZING ANTIBODY; TRANSCRIPTION FACTOR SP1; VASCULOTROPIN; VASCULOTROPIN ANTIBODY; VASCULOTROPIN RECEPTOR 2;

ARTERY MUSCLE; ARTICLE; ATHEROGENESIS; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY; DNA SYNTHESIS; ENDOTHELIUM CELL; FIBROBLAST; GENE ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; MOLECULAR RECOGNITION; NONHUMAN; PARACRINE SIGNALING; PHENOTYPE; PREPUCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN SECRETION; SITE DIRECTED MUTAGENESIS; SMOOTH MUSCLE FIBER; STATISTICAL SIGNIFICANCE; SUPERNATANT; TIME; ULTRAVIOLET RADIATION; UPREGULATION; VASCULAR DISEASE; VIRUS INACTIVATION; VIRUS INFECTION; VIRUS PATHOGENESIS;

CELLS, CULTURED; CYTOMEGALOVIRUS; ENDOTHELIAL CELLS; FIBROBLASTS; HUMANS; MUTAGENESIS, SITE-DIRECTED; PARACRINE COMMUNICATION; PROMOTER REGIONS (GENETICS); RECEPTORS, CELL SURFACE; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

HUMAN HERPESVIRUS 5;

EID: 11444250827     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.80327-0     Document Type: Article

References (32)

1. Almeida, G. D., Porada, C. D., St Jeor, S. & Ascensao, J. L. (1994). Human cytomegalovirus alters interleukin-6 production by endothelial cells. Blood 83, 370-376.
2. Barleon, B., Sozzani, S., Zhou, D., Weich, H. A., Mantovani, A. & Marmé, D. (1996). Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 87, 3336-3343.
3. Browne, E. P., Wing, B., Coleman, D. & Shenk, T. (2001) Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs. J Virol 75, 12319-12330.
4. Celletti, F. L., Waugh, J. M., Amabile, P. G., Brendolan, A., Hilfiker, P. R. & Dake, M. D. (2001). Vascular endothelial growth factor enhances atherosclerotic plaque progression. Nat Med 7 425-429.
5. Chen, Y.-X., Nakashima, Y., Tanaka, K., Shiraishi, S., Nakagawa, K. & Sueishi, K. (1999). Immunohistochemical expression of vascular endothelial growth factor/vascular permeability factor in atherosclerotic intimas of human coronary arteries. Arterioscler Thromb Vasc Biol 19, 131-139.
6. Clauss, M., Gerlach, M., Gerlach, H. & 7 other authors (1990). Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med 172, 1535-1545.
7. Couffinhal, T., Kearney, M., Witzenbichler, B., Chen, D., Murohara, T., Losordo, D. W., Symes, J. & Isner, J. M. (1997). Vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in normal and atherosclerotic human arteries. Am J Pathol 150, 1673-1685.
8. de Boer, O. J., van der Wal, A. C., Teeling, P. & Becker, A. E. (1999). Leucocyte recruitment in rupture prone regions of lipid-rich plaques: a prominent role for neovascularization? Cardiovasc Res 41, 443-449.
9. Finkenzeller, G., Sparacio, A., Technau, A., Marmé, D. & Siemeister, G. (1997). Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression. Oncogene 15, 669-676.
10. Hendrix, M. G., Daemen, M. & Bruggeman, C. A. (1991). Cytomegalovirus nucleic acid distribution within the human vascular tree. Am J Pathol 138, 563-567.
11. Inoue, M., Itoh, H., Ueda, M. & 13 other authors (1998) Vascular endothelial growth factor (VEGF) expression in human coronary atherosclerotic lesions: possible pathophysiological significance of VEGF in progression of atherosclerosis. Circulation 98, 2108-2116.
12. Keck, P. J., Hauser, S. D., Krivi, G., Sanzo, K., Warren, T., Feder, J. & Connolly, D. T. (1989). Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 246, 1309-1312.
13. Lemström, K. B., Krebs, R., Nykänen, A. I. & 8 other authors (2002). Vascular endothelial growth factor enhances cardiac allograft arteriosclerosis. Circulation 105, 2524-2530.
14. Liu, C., Okruzhnov, Y., Li, H. & Nicholas, J. (2001). Human herpesvirus 8 (HHV-8)-encoded cytokines induce expression of and autocrine signaling by vascular endothelial growth factor (VEGF) in HHV-8-infected primary-effusion lymphoma cell lines and mediate VEGF-independent antiapoptotic effects. J Virol 75, 10933-10940.
15. Melnick, J. L., Petrie, B. L., Dreesman, G. R., Burck, J., McCollum, C. H. & DeBakey, M. E. (1983). Cytomegalovirus antigen within human arterial smooth muscle cells. Lancet ii, 644-647.
16. Michel, D., Pavić, I., Zimmermann, A., Haupt E., Wunderlich, K., Heuschmid, M. & Mertens, T. (1996). The UL97 gene product of human cytomegalovirus is an early-late protein with a nuclear localization but is not a nucleoside kinase. J Virol 70, 6340-6347.
17. Minisini, R., Tulone, C., Lüske, A., Michel, D., Mertens, T., Gierschik P. & Moepps, B. (2003). Constitutive inositol phosphate formation in cytomegalovirus-infected human fibroblasts is due to expression of the chemokine receptor homologue pUS28. J Virol 77, 4489-4501.
18. Moulton, K. S., Heller, E., Konerding, M. A., Flynn, E., Palinski, W. & Folkman, J. (1999). Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Circulation 99, 1726-1732.
19. Moulton, K. S., Vakili, K., Zurakowski, D. & 7 other authors (2003). Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis. Proc Natl Acad Sci U S A 100, 4736-4741.
20. Murayama, T., Ohara, Y., Obuchi, M., Khabar, K. S. A., Higashi, H., Mukaida, N. & Matsushima, K. (1997). Human cytomegalovirus induces interleukin-8 production by a human monocytic cell line, THP-1, through acting concurrently on AP-1- and NF-κ B-binding sites of the interleukin-8 gene. J Virol 71, 5692-5695.
21. Reinhardt, B., Minisini, R. & Mertens, T. (2002). Opinion article: cytomegalovirus is a risk factor in atherogenesis. Herpes 9, 21-23.
22. Reinhardt, B., Vaida, B., Voisard, R. & 7 other authors (2003). Human cytomegalovirus infection in human renal arteries in vitro. J Virol Methods 109, 1-9.
23. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989). Molecular Cloning. a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
24. Sedmak, D. D., Knight, D. A., Vook, N. C. & Waldman, J. W. (1994). Divergent patterns of ELAM-1, ICAM-1, and VCAM-1 expression on cytomegalovirus-infected endothelial cells. Transplantation 58 1379-1385.
25. Speir, E., Modali, R., Huang, E. S., Leon, M. B., Shawl, F., Finkel, T. & Epstein, S. E. (1994). Potential role of human cytomegalovirus and p53 interaction in coronary restenosis. Science 265, 391-394.
26. Srivastava, R., Curtis, M., Hendrickson, S., Burns, W. H. & Hosenpud, J. D. (1999). Strain specific effects of cytomegalovirus on endothelial cells: implications for investigating the relationship between CMV and cardiac allograft vasculopathy. Transplantation 68, 1568-1573.
27. Streblow, D. N., Soderberg-Naucler, C., Vieira, J., Smith, P., Wakabayashi, E., Ruchti, F., Mattison, K., Altschuler, Y. & Nelson, J. A. (1999). The human cytomegalovirus chemokine receptor US28 mediates vascular smooth muscle cell migration. Cell 99, 511-520.
28. Waltenberger, J. (1997). Modulation of growth factor action: implications for the treatment of cardiovascular diseases. Circulation 96, 4083-4094.
29. Zachary, I. & Gliki, G. (2001). Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovasc Res 49, 568-581.
30. Zheng, M., Deshpande, S., Lee, S., Ferrara, N. & Rouse, B. T. (2001). Contribution of vascular endothelial growth factor in the neovascularization process during the pathogenesis of herpetic stromal keratitis. J Virol 75, 9828-9835.
31. Zhou, Y. F., Leon, M. B., Waclawiw, M. A., Popma, J. J., Yu, Z. X., Finkel, T. & Epstein, S. E. (1996). Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy. N Engl J Med 335, 624-630.
32. Zhu, H., Cong, J.-P., Mamtora, G., Gingeras, T. & Shenk, T. (1998). Cellular gene expression altered by human cytomegalovirus: global monitoring with oligonucleotide arrays. Proc Natl Acad Sci U S A 95, 14470-14475.