Usefulness of Preoperative Chemoradiation in Locally Advanced Cervical Carcinoma

Gynecologic and Obstetric Investigation

Volumn 57, Issue 2, 2004, Pages 93-99

  Shibata, Kiyosumi ^a   Kikkawa, Fumitaka ^a   Suzuki, Yuka ^a   Terauchi, Mikio ^a   Kajiyama, Hiroaki ^a   Ino, Kazuhiko ^a   Mizutani, Shigehiko ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Anticancer drugs; Arterial infusion; Cervical carcinoma; Concurrent chemoradiation; Figo stages IB2 IIIB; Preoperative chemoradiation

Indexed keywords

CISPLATIN; FLUOROURACIL;

ADULT; AGED; ANEMIA; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; FEMALE; HUMAN; MICROSCOPY; NAUSEA; NEUTROPENIA; PRIORITY JOURNAL; SIDE EFFECT; SQUAMOUS CELL CARCINOMA; THROMBOCYTOPENIA; TREATMENT OUTCOME; UTERINE CERVIX CARCINOMA;

ADENOCARCINOMA; ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CHEMOTHERAPY, ADJUVANT; CISPLATIN; DISEASE-FREE SURVIVAL; FEMALE; FLUOROURACIL; HUMANS; MIDDLE AGED; PREOPERATIVE CARE; RADIOTHERAPY, ADJUVANT; TREATMENT OUTCOME; UTERINE CERVICAL NEOPLASMS;

EID: 1142310556     PISSN: 03787346     EISSN: None     Source Type: Journal    
DOI: 10.1159/000075385     Document Type: Article

References (19)

1. Mohar A, Frias-Mendivil M: Epidemiology of cervical cancer. Cancer Invest 2000;18:584-590.
2. Alvarez RD, Soong SJ, Kinney WK, Reid GC, Schray MF, Podratz KC, Morley GW, Shingleton HM: Identification of prognostic factors and risk groups in patients found to have nodal metastasis at the time of radical hysterectomy for early-stage squamous carcinoma of the cervix. Gynecol Oncol 1989;35:130-135.
3. Delgado G, Bundy B, Zaino R, Sevin BU, Creasman WT, Major F: Prospective surgical-pathological study of disease-free interval in patients with stage IB squamous cell carcinoma of the cervix: A Gynecologic Oncology Group study. Gynecol Oncol 1990;38:352-357.
4. Lin HH, Cheng WF, Chan KW, Chang DY, Chen CK, Huang SC: Risk factors for recurrence in patients with stage IB, IIA, and IIB cervical carcinoma after radical hysterectomy and postoperative pelvic irradiation. Obstet Gynecol 1996;88:274-279.
5. Kamura T, Tsukamoto N, Tsuruchi N, Saito T, Matsuyama T, Akazawa K, Nakano H: Multivariate analysis of the histopathologic prognostic factors of cervical cancer in patients undergoing radical hysterectomy. Cancer 1992;69:181-186.
6. Estape RE, Angioli R, Madrigal M, Janicek M, Gomez C, Penalver M, Averette H: Close vaginal margins as a prognostic factor after radical hysterectomy. Gynecol Oncol 1998;68:229-232.
7. Peters WA 3rd, Liu PY, Barrett RJ 2nd, Stock RJ, Monk BJ, Berek JS, Souhami L, Grigsby P, Gordon W Jr, Alberts DS: Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix. J Clin Oncol 2000;18:1606-1613.
8. Morris M, Eifel PJ, Lu J, Grigsby PW, Levenback C, Stevens RE, Rotman M, Gershenson DM, Mutch DG: Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer. N Engl J Med 1999;340:1137-1143.
9. Keys HM, Bundy BN, Stehman FB, Muderspach LI, Chafe WE, Suggs CL 3rd, Walker JL, Gersell D: Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Engl J Med 1999;340:1154-1161.
10. Rose PG, Bundy BN, Watkins EB, Thigpen JT, Deppe G, Maiman MA, Clarke-Pearson DL, Insalaco S: Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N Engl J Med 1999;340:1144-1153.
11. Resbeut M, Cowen D, Viens P, Noirclerc M, Perez T, Goubernet J, Delpero JR, Gamerre M, Boubli L, Houvenaeghel G: Concomitant chemoradiation prior to surgery in the treatment of advanced cervical carcinoma. Gynecol Oncol 1994;54:68-75.
12. Jurado M, Martines-Monge R, Lopez-Garcia G, Azinovic I, Aristu J, Brugarolas A: Chemoradiation followed by surgery: Its role in local control in advanced cervical cancer. Rays 1998;23:508-521.
13. Mancuso S, Smaniotto D, Benedetti Panici P, Favale B, Greggi S, Manfredi R, Margariti PA, Morganti AG, Scambia G, Tortoreto F, Valentini V, Cellini N: Phase I-II trial of preoperative chemoradiation in locally advanced cervical carcinoma. Gynecol Oncol 2000;78:324-328.
14. Duenas-Gonzalez A, Lopez-Graniel C, Gonzalez-Enciso A, Mohar A, Rivera L, Mota A, Guadarrama R, Chanona G, De La Garza J: Concomitant chemoradiation versus neoadjuvant chemotherapy in locally advanced cervical carcinoma: results from two consecutive phase II studies. Ann Oncol 2002;13:1212-1219.
15. Nagai N, Murakami T, Ohama K: Distribution of platinum in the female genital tract after intraarterial carboplatin infusion during the operation of uterine cervical cancer. Gan To Kagaku Ryoho 1994;21:1975-1979.
16. Ishikawa H, Kikkawa F, Tamakoshi K, Matsuzawa K, Kawai M, Suganuma N, Tomoda Y: Distribution of platinum in human gynecologic tissues and lymph nodes after intravenous and intraarterial neoadjuvant chemotherapy. Anticancer Res 1996;16(6B):3849-3853.
17. Aoki Y, Sato T, Watanabe M, Sasaki M, Tsuneki I, Tanaka K: Neoadjuvant chemotherapy using low-dose consecutive intraarterial infusions of cisplatin combined with 5-fluorouracil for locally advanced cervical adenocarcinoma. Gynecol Oncol 2001;81:496-499.
18. Logsdon MD, Eifel P J: Figo IIIB squamous cell carcinoma of the cervix: An analysis of prognostic factors emphasizing the balance between external beam and intracavitary radiation therapy. Int J Radiat Oncol Biol Phys 1999;43:763-775.
19. Benedetti-Panici P, Greggi S, Colombo A, Amoroso M, Smaniotto D, Gianarelli D, Amunni G, Raspagliesi F, Zola P, Mangioni C, Landoni F: Neoadjuvant chemotherapy and radical surgery versus exclusive radiotherapy in locally advanced squamous cell cervical cancer: Results from the Italian multicenter randomized study. J Clin Oncol 2002;20:179-188.