Mucosal immunization of CD4 + T cell-deficient mice with an inactivated virus induces IgG and IgA responses in serum and mucosal secretions

Virology

Volumn 331, Issue 2, 2005, Pages 387-395

  Sha, Zhiyi ^a   Kang, Sang Moo ^a   Compans, Richard W ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CD4 + T cells; Mice; Mucosal immunization

Indexed keywords

FORMALDEHYDE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN M;

ANTIBODY AFFINITY; ARTICLE; CONTROLLED STUDY; IMMUNOGLOBULIN PRODUCTION; INFLUENZA VIRUS A; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS INACTIVATION; VIRUS INDUCTION;

ANIMALS; ANTIBODIES, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; GENE DELETION; IGA DEFICIENCY; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INFLUENZA VACCINES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; VACCINATION; VACCINES, INACTIVATED;

INFLUENZA VIRUS;

EID: 11344264155     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2004.10.014     Document Type: Article

References (37)

1. M.F. Bachmann, and R.M. Zinkernagel The influence of virus structure on antibody responses and virus serotype formation Immunol. Today 17 12 1996 553 558
2. M.F. Bachmann, T.M. Kundig, C.P. Kalberer, H. Hengartner, and R.M. Zinkernagel Formalin inactivation of vesicular stomatitis virus impairs T-cell-but not T-help-independent B-cell responses J. Virol. 67 7 1993 3917 3922
3. M.F. Bachmann, C. Bast, H. Hengartner, and R.M. Zinkernagel Immunogenicity of a viral model vaccine after different inactivation procedures Med. Microbiol. Immunol. 183 2 1994 95 104
4. M.F. Bachmann, A. Oxenius, T.W. Mak, and R.M. Zinkernagel T cell development in CD8-/-mice. Thymic positive selection is biased toward the helper phenotype J. Immunol. 155 8 1995 3727 3733
5. R.L. Coffman, and J. Carty A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma J. Immunol. 136 3 1986 949 954
6. A. Di Tommaso, G. Saletti, M. Pizza, R. Rappuoli, G. Dougan, S. Abrignani, G. Douce, and M.T. De Magistris Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant Infect. Immun. 64 3 1996 974 979
7. F.D. Finkelman, I.M. Katona, J.F. Urban Jr., J. Holmes, J. Ohara, A.S. Tung, J.V. Sample, and W.E. Paul IL-4 is required to generate and sustain in vivo IgE responses J. Immunol. 141 7 1988 2335 2341
8. F.D. Fnkelman, J. Holmes, I.M. Katona, J.F. Urban Jr., M.P. Beckmann, L.S. Park, K.A. Schooley, R.L. Coffman, T.R. Mosmann, and W.E. Paul Lymphokine control of in vivo immunoglobulin isotype selection Annu. Rev. Immunol. 8 1990 303 333
9. C.E. Hornquist, L. Ekman, K.D. Grdic, K. Schon, and N.Y. Lycke Paradoxical IgA immunity in CD4-deficient mice. Lack of cholera toxin-specific protective immunity despite normal gut mucosal IgA differentiation J. Immunol. 155 6 1995 2877 2887
10. P.C. Isakson, E. Pure, E.S. Vitetta, and P.H. Krammer T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells J. Exp. Med. 155 3 1982 734 748
11. R.M. Locksley, S.L. Reiner, F. Hatam, D.R. Littman, and N. Killeen Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice Science 261 5127 1993 1448 1451
12. K.J. Maloy, B. Odermatt, H. Hengartner, and R.M. Zinkernagel Interferon gamma-producing gammadelta T cell-dependent antibody isotype switching in the absence of germinal center formation during virus infection Proc. Natl. Acad. Sci. U.S.A. 95 3 1998 1160 1165
13. T.M. McIntyre, D.R. Klinman, P. Rothman, M. Lugo, J.R. Dasch, J.J. Mond, and C.M. Snapper Transforming growth factor beta 1 selectivity stimulates immunoglobulin G2b secretion by lipopolysaccharide-activated murine B cells J. Exp. Med. 177 4 1993 1031 1037
14. P. Mombaerts, A.R. Clarke, M.A. Rudnicki, J. Iacomini, S. Itohara, J.J. Lafaille, L. Wang, Y. Ichikawa, R. Jaenisch, and M.L. Hooper Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages Nature 360 6401 1992 225 231
15. T.R. Mosmann, and R.L. Coffman TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties Annu. Rev. Immunol. 7 1989 145 173
16. H.H. Nguyen, Z. Moldoveanu, M.J. Novak, F.W. van Ginkel, E. Ban, H. Kiyono, J.R. McGhee, and J. Mestecky Heterosubtypic immunity to lethal influenza A virus infection is associated with virus-specific CD8(+) cytotoxic T lymphocyte responses induced in mucosa-associated tissues Virology 254 1 1999 50 60
17. M. Novak, Z. Moldoveanu, D.P. Schafer, J. Mestecky, and R.W. Compans Murine model for evaluation of protective immunity to influenza virus Vaccine 11 1 1993 55 60
18. A. Oxenius, R.M. Zinkernagel, and H. Hengartner CD4+ T-cell induction and effector functions: a comparison of immunity against soluble antigens and viral infections Adv. Immunol. 70 1998 313 367
19. D.C. Parker T cell-dependent B cell activation Annu. Rev. Immunol. 11 1993 331 360
20. T.M. Pertmer, T.R. Roberts, and J.R. Haynes Influenza virus nucleoprotein-specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery J. Virol. 70 9 1996 6119 6125
21. A. Rahemtulla, W.P. Fung-Leung, M.W. Schilham, T.M. Kundig, S.R. Sambhara, A. Narendran, A. Arabian, A. Wakeham, C.J. Paige, and R.M. Zinkernagel Normal development and function of CD8+cells but markedly decreased helper cell activity in mice lacking CD4 Nature 353 6340 1991 180 184
22. A. Rahemtulla, T.M. Kundig, A. Narendran, M.F. Bachmann, M. Julius, C.J. Paige, P.S. Ohashi, R.M. Zinkernagel, and T.W. Mak Class II major histocompatibility complex-restricted T cell function in CD4-deficient mice Eur. J. Immunol. 24 9 1994 2213 2218
23. K.B. Renegar, and P.A. Small Jr. Immunoglobulin A mediation of murine nasal anti-influenza virus immunity J. Virol. 65 4 1991 2146 2148
24. K.B. Renegar, and P.A. Small Jr. Passive transfer of local immunity to influenza virus infection by IgA antibody J. Immunol. 146 6 1991 1972 1978
25. J. Rose, M. Franco, and H. Greenberg The immunology of rotavirus infection in the mouse Adv. Virus Res. 51 1998 203 235
26. M.W. Russell, Z. Moldoveanu, P.L. White, G.J. Sibert, J. Mestecky, and S.M. Michalek Salivary, nasal, genital, and systemic antibody responses in monkeys immunized intranasally with a bacterial protein antigen and the Cholera toxin B subunit Infect. Immun. 64 4 1996 1272 1283
27. S. Schurmans, C.H. Heusser, H.Y. Qin, J. Merino, G. Brighouse, and P.H. Lambert In vivo effects of anti-IL-4 monoclonal antibody on neonatal induction of tolerance and on an associated autoimmune syndrome J. Immunol. 145 8 1990 2465 2473
28. Z. Sha, and R.W. Compans Induction of CD4(+) T-cell-independent immunoglobulin responses by inactivated influenza virus J. Virol.. 74 11 2000 4999 5005
29. C.M. Snapper, and J.J. Mond Towards a comprehensive view of immunoglobulin class switching Immunol. Today 14 1 1993 15 17
30. C.M. Snapper, and W.E. Paul Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production Science 236 4804 1987 944 947
31. E. Sonoda, R. Matsumoto, Y. Hitoshi, T. Ishii, M. Sugimoto, S. Araki, A. Tominaga, N. Yamaguchi, and K. Takatsu Transforming growth factor beta induces IgA production and acts additively with interleukin 5 for IgA production J. Exp. Med. 170 4 1989 1415 1420
32. E. Szomolanyi-Tsuda, and R.M. Welsh T cell-independent antibody-mediated clearance of polyoma virus in T cell-deficient mice J. Exp. Med. 183 2 1996 403 411
33. E. Szomolanyi-Tsuda, and R.M. Welsh T-cell-independent antiviral antibody responses Curr. Opin. Immunol. 10 4 1998 431 435
34. E. Szomolanyi-Tsuda, Q.P. Le, R.L. Garcea, and R.M. Welsh T-cell-independent immunoglobulin G responses in vivo are elicited by live-virus infection but not by immunization with viral proteins or virus-like particles J. Virol. 72 8 1998 6665 6670
35. S. Tamura, H. Funato, Y. Hirabayashi, K. Kikuta, Y. Suzuki, T. Nagamine, C. Aizawa, M. Nakagawa, and T. Kurata Functional role of respiratory tract haemagglutinin-specific IgA antibodies in protection against influenza Vaccine 8 5 1990 479 485
36. J.L. VanCott, M.M. McNeal, J. Flint, S.A. Bailey, A.H. Choi, and R.L. Ward Role for T cell-independent B cell activity in the resolution of primary rotavirus infection in mice Eur. J. Immunol. 31 11 2001 3380 3387
37. J.L. Viney, L. Dianda, S.J. Roberts, L. Wen, C.A. Mallick, A.C. Hayday, and M.J. Owen Lymphocyte proliferation in mice congenitally deficient in T-cell receptor alpha beta+ cells Proc. Natl. Acad. Sci. U.S.A. 91 25 1994 11948 11952