β 2-adrenergic receptor regulation of human neutrophil function is sexually dimorphic

British Journal of Pharmacology

Volumn 143, Issue 8, 2004, Pages 1033-1041

  De Coupade, Catherine ^a,d   Gear, Robert W ^a   Dazin, Paul F ^b   Sroussi, Herve Y ^c   Green, Paul G ^a   Levine, Jon D ^a,c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Diatos SA   (France)

Author keywords

adrenergic receptor; Cell recruitment; Chemokine; Chemokinesis; Chemotaxis; Inflammation; Polymorphonuclear leucocytes; Sex differences

Indexed keywords

1 (2 BROMOPHENYL) 3 (2 HYDROXY 4 NITROPHENYL)UREA; 3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ADRENALIN; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CHEMOKINE; CHEMOKINE RECEPTOR CXCR2; DIHYDROALPRENOLOL; G PROTEIN COUPLED RECEPTOR; INTERLEUKIN 8; ISOPRENALINE; LIGAND; NORADRENALIN; RECOMBINANT INTERLEUKIN 8; RNA; TRITIUM;

ADRENALIN BLOOD LEVEL; ADRENERGIC SYSTEM; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; INFLAMMATION; MALE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NORADRENALIN BLOOD LEVEL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; WESTERN BLOTTING;

ADULT; CELL LINE; CELL MOVEMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; ISOPROTERENOL; MALE; MIDDLE AGED; NEUTROPHILS; RECEPTORS, ADRENERGIC, BETA-2; SEX CHARACTERISTICS;

EID: 11244316250     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705972     Document Type: Article

References (52)

1. AJUEBOR, M.N., SWAIN, M.G. & PERRETTI, M. (2002). Chemokines as novel therapeutic targets in inflammatory diseases. Biochem. Pharmacol., 63, 1191-1196.
2. ALLEN, J.B., BLATTER, D., CALANDRA, G.B. & WILDER, R.L. (1983). Sex hormonal effects on the severity of streptococcal cell wall-induced polyarthritis in the rat. Arthritis. Rheum., 26, 560-563.
3. BARNES, P.J. (1998). Anti-inflammatory actions of glucocorticoids: molecular mechanisms. Clin. Sci. (Colch.), 94, 557-572.
4. BARNES, P.J. (1999). Effect of beta-agonists on inflammatory cells. J. Allergy. Clin. Immunol., 104, S10-S17.
5. BERKOWITZ, D.E., NARDONE, N.A., SMILEY, R.M., PRICE, D.T., KREUTTER, D.K., FREMEAU, R.T. & SCHWINN, D.A. (1995). Distribution of beta 3-adrenoceptor mRNA in human tissues. Eur. J. Pharmacol., 289, 223-228.
6. BUCKLEY, C.D. (2003). Michael Mason prize essay 2003. Why do leucocytes accumulate within chronically inflamed joints? Rheumatology (Oxford), 42, 1433-1444.
7. CAMPBELL, J.J., FOXMAN, E.F. & BUTCHER, E.G. (1997). Chemoattractant receptor cross talk as a regulatory mechanism in leukocyte adhesion and migration. Eur. J. Immunol., 27, 2571-2578.
8. CASSATELLA, M.A. (1995). The production of cytokines by polymorphonuclear neutrophils. Immunol. Today, 16, 21-26.
9. CASTAGNETTA, L., GRANATA, O.M., TRAINA, A., COCCIADIFERRO, L., SAETTA, A., STEFANO, R., CUTOLO, M. & CARRUBA, G. (2002). A role for sex steroids in autoimmune diseases: a working hypothesis and supporting data. Ann. N Y Acad. Sci., 966, 193-203.
10. CODERRE, T.J., BASBAUM, A.I., DALLMAN, M.F., HELMS, C. & LEVINE, J.D. (1990). Epinephrine exacerbates arthritis by an action at presynaptic B2-adrenoceptors. Neuroscience. 34, 521-523.
11. DA SILVA, J.A. (1995). Sex hormones, glucocorticoids and autoimmunity: facts and hypotheses. Ann. Rheum. Dis., 54, 6-16.
12. DAVIS, S.N., SHAVERS, C. & COSTA, F. (2000). Differential gender responses to hypoglycemia are due to alterations in CNS drive and not glycemic thresholds. Am. J. Physiol. Endocrinol. Metab., 279, E1054-E1063.
13. ELFERINK, J.G. & VANUFFELEN, B.E. (1996). The role of cyclic nucleotides in neutrophil migration. Gen. Pharmacol., 27, 387-393.
14. FELDMANN, M., BRENNAN, P.M. & MAINI, R.N. (1996). Rheumatoid arthritis. Cell. 85, 307-310.
15. FOXMAN, E.F., CAMPBELL, J.J. & BUTCHER, B.C. (1997). Multistep navigation and the combinatorial control of leukocyte chemotaxis. J. Cell Biol., 139, 1349-1360.
16. GAILLARD, R.C. & SPINEDI, E. (1998). Sex- and stress-steroids interactions and the immune system: evidence for a neuroendocrine-immunological sexual dimorphism. Domest. Anim. Endocrinol., 15, 345-352.
17. GARCIA-RAMALLO, E., MARQUES, T., PRATS, N., BELETA, J., KUNKEL, S.L. & GODESSART, N. (2002). Resident cell chemokine expression serves as the major mechanism for leukocyte recruitment during local inflammation. J. Immunol., 169, 6467-6473.
18. GEELEN, G., LAITINEN, T., HARTIKAINEN, J., LANSIMIES, E., BERGSTROM, K. & NISKANEN, L. (2002). Gender influence on vasoactive hormones at rest and during a 70 degrees head-up tilt in healthy humans. J. Appl. Physiol., 92, 1401-1408.
19. GOLDSTEIN, D.S., EISENHOFER, G.F. & KOPIN, I.J. (2003). Sources and significance of plasma levels of catechols and their metabolites in humans. J. Pharmacol. Exp. Ther., 20, 20.
20. GOULDING, N.J., EUZGER, H.S., BUTT, S.K. & PERRETTI, M. (1998). Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation. Inflamm. Res., 47 (Suppl. 3), S158-S165.
21. GREEN, M.S. (1992). The male predominance in the incidence of infectious diseases in children: a postulated explanation for disparities in the literature. Int. J. Epidemiol., 21, 381-386.
22. GREEN, P.G., DAHLQVIST, S.R., ISENBERG, W.M., STRAUSBAUGH, H.J., MIAO, F.J. & LEVINE, J.D. (1999). Sex steroid regulation of the inflammatory response: sympathoadrenal dependence in the female rat. J. Neurosci., 19, 4082-4089.
23. GREEN, P.O., JÄNIG, W. & LEVINE, J.D. (1997). Negative feedback neuroendocrine control of inflammatory response in the rat is dependent on the sympathetic postganglionic neuron. J. Neurosci., 17, 3234-3238.
24. GREEN, P.O., LUO, J., HELLER, P.H. & LEVINE, J.D. (1993). Further substantiation of a significant role for the sympathetic nervous system in inflammation. Neuroscience, 55, 1037-1043.
25. GRIFFITHS, M.M., SAWITZKE, A.D., HARPER, D.S., MCCALL, S., REESE, V.R. & CANNON, G.W. (1994). Exacerbation of collagen-induced arthritis in rats by rat cytomegalovirus is antigen-specific. Autoimmunity, 18, 177-187.
26. JOHNSON, M. (2002). Effects of beta2-agonists on resident and infiltrating inflammatory cells. J. Allergy. Clin. Immunol., 110, S282-S290.
27. KAVELAARS, A., VAN DE POL, M., ZIJLSTRA, J. & HEIJNEN, C.J. (1997). Beta 2-adrenergic activation enhances interleukin-8 production by human monocytes. J. Neuroimmunol., 77, 211-216.
28. KOYAMA, S., SATO, E., MASUBUCHI, T., TAKAMIZAWA, A., KUBO, K., NAGAI, S. & ISUMI, T. (1999). Procaterol inhibits IL-1 beta- and TNF-alpha-mediated epithelial cell eosinophil chemotactic activity. Eur. Respir. J., 14, 767-775.
29. LAEMMLI, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
30. LINDEN, A. (1996). Increased interleukin-8 release by beta-adrenoceptor activation in human transformed bronchial epithelial cells. Br. J. Pharmacol., 119, 402-406.
31. LOMBARDI, M.S., KAVELAARS, A., SCHEDLOWSKI, M., BIJLSMA, J.W., OKIHARA, K.L., VAN DE POL, M., OCHSMANN, S., PAWLAK, C., SCHMIDT, R.E. & HEUNEN, C.J. (1999). Decreased expression and activity of G-protein-coupled receptor kinases in peripheral blood mononuclear cells of patients with rheumatoid arthritis. FASEB. J., 13, 715-725.
32. MAESTRONI, G.J. (2000). Dendritic cell migration controlled by alpha 1b-adrenergic receptors. J. Immunol., 165, 6743-6747.
33. MARCHETTI, B., MORALE, M.C., PARADIS, P. & BOUVIER, M. (1994). Characterization, expression, and hormonal control of a thymic beta 2-adrenergic receptor. Am. J. Physiol., 267, E718-E731.
34. MILLS, P.J., GOEBEL, M., REHMAN, J., IRWIN, M.R. & MAISEL, A.S. (2000). Leukocyte adhesion molecule expression and T cell naive/memory status following isoproterenol infusion. J. Neuroimmunol., 102, 137-144.
35. NEPTUNE, E.R. & BOURNE, H.R. (1997). Receptors induce chemotaxis by releasing the betagamma subunit of Gi, not by activating Gq or Gs. Proc. Natl. Acad. Sci. U.S.A., 94, 14489-14494.
36. OTTONELLO, L., MORONE, P., DAPINO, P. & DALLEGRI, F. (1996). Inhibitory effect of salmeterol on the respiratory burst of adherent human neutrophils. Clin. Exp. Immunol., 106, 97-102.
37. PACAK, K., BAFFI, J.S., KVETNANSKY, R., GOLDSTEIN, D.S. & PALKOVITS, M. (1998). Stressorspecific activation of catecholaminergic systems: implications for stress-related hypothalamic-pituitary-adrenocortical responses. Adv. Pharmacol., 42, 561-564.
38. PRAUSE, O., LAAN, M., LOTVALL, J. & LINDEN, A. (2003). Pharmacological modulation of interleukin-17-induced GCP-2-, GRO-alpha- and interleukin-8 release in human bronchial epithelial cells. Eur. J. Pharmacol., 462, 193-198.
39. RIBEIRO, F.P., FURLANETO, C.J., HATANAKA, E., RIBEIRO, W.B., SOUZA, G.M., CASSATELLA, M.A. & CAMPA, A. (2003). mRNA expression and release of interleukin-8 induced by serum amyloid A in neutrophils and monocytes. Mediators Inflamm., 12, 173-178.
40. SANDNES, D., GJERDE, I., REFSNES, M. & JACOBSEN, S. (1987). Down-regulation of surface beta-adrenoceptors on intact human mononuclear leukocytes. Time-course and isoproterenol concentration dependence. Biochem. Pharmacol., 36, 1303-1311.
41. SILVESTRI, M., ODDERA, S., LANTERO, S. & ROSSI, G.A. (1999). beta 2-agonist-induced inhibition of neutrophil chemotaxis is not associated with modification of LFA-1 and Mac-1 expression or with impairment of polymorphonuclear leukocyte antibacterial activity. Respir. Med., 93, 416-423.
42. SPITZER, J.A. (1999). Gender differences in some host defense mechanisms. Lupus, 8, 380-383.
43. STEVENS, P.A. & MILLIGAN, G. (1998). Efficacy of inverse agonists in cells overexpressing a constitutively active beta2-adrenoceptor and type II adenylyl cyclase. Br. J. Pharmacol., 123, 335-343.
44. STRAUB, R.H., MAYER, M., KREUTZ, M., LEEB, S., SCHOLMERICH, J. & FALK, W. (2000). Neurotransmitters of the sympathetic nerve terminal are powerful chemoattractants for monocytes. J. Leukoc. Biol., 67, 553-558.
45. STRAUSBAUGH, H.J., DALLMAN, M.F. & LEVINE, J.D. (1999). Repeated, but not acute, stress suppresses inflammatory plasma extravasation. Proc. Natl. Acad. Sci. U.S.A., 96, 14629-14634.
46. STRUYF, S., PROOST, P., LENAERTS, J.P., STOOPS, G., WUYTS, A. & VAN DAMME, J. (2001). Identification of a blood-derived chemoattractant for neutrophils and lymphocytes as a novel CC chemokine, Regakine-1. Blood, 97, 2197-2204.
47. SWAIN, M.G. (2000). I. Stress and hepatic inflammation. Am. J. Physiol. Gastrointest. Liver Physiol., 279, G1135-G1138.
48. TAN, K.S., MCFARLANE, L.C. & LIPWORTH, B.J. (1997). Paradoxical down-regulation and desensitization of beta2-adrenoceptors by exogenous progesterone in female asthmatics. Chest, 111, 847-851.
49. VON ZASTROW, M. & KOBILKA, B.K. (1992). Ligand-regulated internalization and recycling of human beta 2- adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors. J. Biol. Chem., 267, 3530-3538.
50. WAHLE, M., STACHETZKI, U., KRAUSE, A., PIERER, M., HANTZSCHEL, H. & BAERWALD, C.G. (2001). Regulation of beta(2)-adrenergic receptors on CD4 and CD8 positive lymphocytes by cytokines in vitro. Cytokine, 16, 205-209.
51. WILDER, R.L., CALANDRA, G.B., GARVIN, A.J., WRIGHT, K.D. & HANSEN, C.T. (1982). Strain and sex variation in the susceptibility to streptococcal cell wall-induced polyarthritis in the rat. Arthritis Rheum., 25, 1064-1072.
52. ZHOU, Y.Y., YANG, D., ZHU, W.Z., ZHANG, S.J., WANG, D.J., ROHRER, D.K., DEVIC, E., KOBILKA, B.K., LAKATTA, E.G., CHENG, H. & XIAO, R.P. (2000). Spontaneous activation of beta(2)- but not beta(1)-adrenoceptors expressed in cardiac myocytes from beta(1)beta(2) double knockout mice. Mol. Pharmacol., 58, 887-894.