Transformation of trichothecenes in ileal digesta and faeces from pigs

Archives of Animal Nutrition/Archiv fur Tierernahrung

Volumn 56, Issue 4, 2002, Pages 263-274

  Eriksen, Gunnar Sundstøl ^a   Pettersson, H ^a   Johnsen, K ^b   Lindberg, J E ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

De epoxidation; Deoxynivalenol; Intestinal metabolism; Pig; T RFLP; Trichothecenes

Indexed keywords

BACTERIAL DNA; NIVALENOL; TRICHOTHECENE DERIVATIVE; VOMITOXIN;

ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; BIOTRANSFORMATION; CHEMISTRY; CHROMATOGRAPHY; FECES; FOOD CONTAMINATION; GERMFREE ANIMAL; ILEUM; MALE; METABOLISM; MICROBIOLOGY; STOMACH JUICE; SWINE;

ANIMAL FEED; ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY; DNA, BACTERIAL; FECES; FOOD CONTAMINATION; GASTROINTESTINAL CONTENTS; ILEUM; MALE; SPECIFIC PATHOGEN-FREE ORGANISMS; SWINE; TRICHOTHECENES;

EID: 11244302534     PISSN: 0003942X     EISSN: None     Source Type: Journal    
DOI: 10.1080/00039420214343     Document Type: Article

References (21)

1. Bauer, J., Gareis, M. and Gedek, B. (1989) Metabolism of the trichothecenes T-2 toxin, diacetoxyscirpenol, and deoxynivalenol by farm animals. In: Chelkowski, J.(Ed.) Fusarium mycotoxins, taxonomy and pathogenicity. Topics in Secondary Metabolism, Vol 2. Elsevier, pp. 139-165.
2. He, P., Young, L. G. and Forsberg, C. (1992) Microbial transformation of deoxynivalenol (vomitoxin). Appl. Environ. Microbiol., 58, 3857-3863.
3. Hedman, R. (1996) Toxicology of nivalenol in farm animals, and methods of its production and analysis. Acta Universitatis agriculturae Sueciae. Agraria 10. Swedish Univ. of Agricultural Sciences,
4. Hedman, R. and Pettersson, H. (1997) Transformation of nivalenol by gastrointestinal microbes. Arch. Anim. Nutr., 50, 321-329.
5. Hedman, R., Pettersson, H. and Lindberg, J. E. (1997) Absorption and metabolism of nivalenol in pigs. Arch. Anim. Nutr., 50, 13-24.
6. Kollarczik, B., Gareis, M. and Hanelt, M. (1994) In vitro transformation of the Fusarium mycotoxins deoxynivalenol and zearalenone by the normal gut microflora of pigs. Nat. Toxins 2, 105-110.
7. Langseth, W., Bernhoft, A., Rundberget, T., Kosiak, B. and Gareis, M. (1998) Mycotoxin production and cytotoxicity of Fusarium strains isolated from Norwegian cereals. Mycopathologia 144, 103-113.
8. Lauber, U., Dillenburger, T., Schollenberg, M., Müller, H. M. and Drochner, W. (2000) Transformation von Deoxynivalenol durch die Darmflora des Schweines - In-Vitro Untersuchungen zur Adaption in Abhängigkeit von der Darreichungsform. Mycotox. Res., 16 A, 166-169.
9. Leser, T. D., Lindecrona, R. H., Jensen, T. K., Jensen, B. B. and Møller, K. (2000) Changes in bacterial community structure in the colon of pigs fed different experimental diets and after infection with Brachyspira hyodysenteriae. Appl. Environ. Microbiol., 66, 3290-3296.
10. Pesti, L. (1962) Qualitative and quantitative examination of the bacteria flora in the intestines of healthy pigs. I. Intestinal bacterial flora of pigs of different ages. Acta Vet. Hung., 12, 299-310.
11. Placinta, C. M., Mello, J. P. F. and Macdonald, A. M. C. (1999) A review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins. Anim. Feed Sci. Technol., 78, 21-37.
12. 14C-labeled deoxynivalenol in swine. Fundam. Appl. Toxicol., 10, 276-286.
13. Rotter, B. A., Prelusky, D. B. and Pestka, J. J. (1996) Toxicology of deoxynivalenol (Vomitoxin). J. Toxicol. Environ. Health 48, 1-34.
14. Schulze, F. and Bathke, W. (1977) Zur quantitativen Zusammensetzung der Magen-Darm-Flora beim Läuferschwein. Arch. Exp. Veterinärmed., 31, 161-185.
15. Simonsson, A. (1994) Näringsrekommendationer och fodermedelstabeller til svin SLU info rapporter, Uppsala, Sweden
16. Swanson, S. P. and Corley, R. A. (1989) The distribution, metabolism, and excretion of trichothecene mycotoxins. In: Beasley, V. R. (Ed.) Trichothecene mycotoxicosis pathophysiologic effects Volume I. CRC Press, Boca Raton, Florida, U.S.A. pp. 37-61.
17. Swanson, S. P., Helaszek, C., Buck, W. B., Rood Jr, H. D. and Haschek, W. M. (1988) The role of intestinal microflora in the metabolism of trichothecene mycotoxins. Food Chem. Toxicol., 26, 823-829.
18. Trenholm, H. L., Friend, D. W., Hamilton, R. M. G., Prelusky, D. B. and Foster, B. C. (1989) Lethal toxicity and nonspecific effects. In: Beasley, V. R. (Ed.) Trichothecene mycotoxicosis pathophysiologic effects Volume I. CRC Press. Boca Raton, Florida, U.S.A. pp. 107-141.
19. Ueno, Y. (1977) Mode of action of trichothecenes. Ann. Nutr. Aliment., 31, 885-900.
20. van Leeuwen, P., van Kleef, D. J., van Kempen, G. J. M., Huisman, J. and Verstegen, M. W. A. (1991) The post-valve T-caecum cannulation technique in pigs applicated to determine digestibility of amino acid in maize, groundnut and sunflower meal. J. Anim. Physiol. a. Anim. Nutr., 65, 183-193.
21. Wilson, K. (1988) Preparation of genomic DNA from bacteria. In: Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Smith, J. A., Seidman, J. G. and Struhl, K. (Eds.) Current protocols in molecular biology John Wiley & Sons, Inc, New York, U.S.A. pp. 241-245.