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Axonal protection using flecainide in experimental autoimmune encephalomyelitis
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Bechtold DA, Yue X, Evans RM, Davies M, Gregson NA, Smith KJ. Axonal protection in experimental autoimmune neuritis by the sodium channel blocking agent flecainide. Brain. In press 2005.
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Sodium channels contribute to microglia/macrophage activation and function in EAE and MS
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A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons
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NaN, a novel voltage-gated Na channel preferentially expressed in peripheral sensory neurons and down-regulated following axotomy
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Blockers of sodium and calcium entry protect axons form nitric oxide-mediated degeneration
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Kapoor R, Davies M, Blaker PA, Hall SM, Smith KJ. Blockers of sodium and calcium entry protect axons form nitric oxide-mediated degeneration. Ann Neurol 2003; 53: 74-80.
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Neuroprotection of axons with phenytoin in experimental allergic encephalomyelitis
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Phenytoin protects spinal cord axons and preserves axonal conduction and neurological function in a model of neuroinflammation in vivo
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Tertiary and quaternary local anesthetics protect CNS white matter from anoxic injury at concentrations that do not block excitability
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