The influence of the amino acid substitution I98K on the catalytic activity of baboon cytochrome P450 side-chain cleavage (CYP11A1)

Endocrine Research

Volumn 30, Issue 4, 2004, Pages 761-767

  Storbeck, K H ^a   Swart, P ^a   Graham, S ^b   Swart, A C ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Baboon; P450 side chain cleavage

Indexed keywords

25 HYDROXYCHOLESTEROL; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); PREGNENOLONE;

ADRENAL CORTEX; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL TISSUE; BABOON; CATALYSIS; CELL STRAIN COS1; CONFERENCE PAPER; CONTROLLED STUDY; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME STRUCTURE, FUNCTION AND VARIABILITY; GENE EXPRESSION; MOLECULAR CLONING; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; SEQUENCE HOMOLOGY; STEROIDOGENESIS;

AMINO ACID SUBSTITUTION; ANIMALS; CATALYSIS; CERCOPITHECUS AETHIOPS; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; COS CELLS; ISOLEUCINE; LYSINE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PAPIO; TRANSFECTION;

EID: 11244292228     PISSN: 07435800     EISSN: None     Source Type: Journal    
DOI: 10.1081/ERC-200044031     Document Type: Conference Paper

References (14)

1. Chung B-C, Mattesen KJ, Voutilainen R, Mohandas TK, Miller WL. Proc Natl Acad Sci U S A 1986; 83:8962-8966.
2. Woods ST, Sadleir J, Downs T, Triantopoulos T, Headlam M, Tuckey RC. Arch Biochem Biophys 1998; 353:109-115.
3. Vilchis F, Chávez B, Larrea F, Timossi C, Montiel F. Gen Comp Endocrinol 2002; 126:279-286.
4. Usanov SA, Graham S, Lepesheva GI, Azeva TN, Strushkevich NV, Gilep AA, Estabrook RW, Peterson JA. Biochemistry 2002; 41:8310-8320.
5. Peterson JA, Graham SE. Structure 1998; 6:1079-1085.
6. Graham-Lorence S, Peterson JA. FASEB J 1996; 10:206-214.
7. Bechtel S, Belkina N, Bernhardt R. Eur J Biochem 2002; 296:1118-1127.
8. Swart AC, Brown N, Kolar N, Swart P. Endocr Res 2000; 26:1011-1018.
9. Swart AC, Kolar NW, Lombard N, Mason JI, Swart P. Eur J Biochem 2002; 269:5608-5616.
10. Hurt EC, van Loon APGM. Trends Biochem Sci 1986; 11:204-207.
11. von Heijne G. EMBO J 1986; 5:1335-1342.
12. Stocco DM, Clark BJ. Endocr Rev 1996; 17:221-244.
13. Lambeth JD, Kitchen SE, Farooqui AA, Tuckey R, Kamin H. J Biol Chem 1982; 257:1876-1884.
14. Ravichandran KG, Boddupalli SS, Hasemann CA, Peterson JA, Deisenhofer J. Science 1993; 261:731-736.