Characterization and quantification of metabolites of racemic ketoprofen excreted in urine following oral administration to man by 1H-NMR spectroscopy, directly coupled HPLC-MS and HPLC-NMR, and circular dichroism

Xenobiotica

Volumn 34, Issue 11-12, 2004, Pages 1075-1089

  Skordi, E ^a   Wilson, I D ^b   Lindon, J C ^a   Nicholson, J K ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 [3 (3 HYDROXYBENZOYL)PHENYL]PROPANOIC ACID; 2 [3 (4 HYDROXYBENZOYL)PHENYL]PROPANOIC ACID; 2 [3 [HYDROXY(PHENYL)METHYL]PHENYL]PROPANOIC ACID; DRUG METABOLITE; KETOPROFEN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CIRCULAR DICHROISM; DRUG CONJUGATION; DRUG METABOLISM; DRUG URINE LEVEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; PROTON NUCLEAR MAGNETIC RESONANCE; RACEMIZATION; STEREOCHEMISTRY; URINARY EXCRETION;

ADMINISTRATION, ORAL; ADULT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; FEMALE; GLUCURONIDES; HUMANS; KETOPROFEN; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PROTONS;

EID: 11244288218     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/00498250412331281098     Document Type: Article

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