The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C

Journal of Biological Chemistry

Volumn 279, Issue 53, 2004, Pages 55499-55505

  Kamath Loeb, Ashwini S ^a   Welcsh, Piri ^b   Waite, Maureen ^b   Adman, Elinor T ^a   Loeb, Lawrence A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DNA; ESCHERICHIA COLI; HYDROLYSIS; PROTEINS;

POLYMORPHISM; RECESSIVE DISORDER; WERNER SYNDROME (WS);

ENZYMES;

ADENOSINE TRIPHOSPHATE; AMINO ACID; ARGININE; CYSTEINE; EXONUCLEASE; HELICASE; WERNER SYNDROME PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DNA DENATURATION; ENZYME ACTIVITY; ENZYME STRUCTURE; ESCHERICHIA COLI; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; HYDROLYSIS; MUTATION; NONHUMAN; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MODIFICATION; RECESSIVE INHERITANCE; SINGLE NUCLEOTIDE POLYMORPHISM; WERNER SYNDROME; WILD TYPE;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AGING; ALLELES; ARGININE; CELL LINE; CYSTEINE; DNA; DNA HELICASES; DNA, COMPLEMENTARY; ESCHERICHIA COLI; GENE FREQUENCY; GENOTYPE; HETEROZYGOTE; HUMANS; HYDROLYSIS; IMMUNOPRECIPITATION; MODELS, GENETIC; MODELS, MOLECULAR; MUTATION; PLASMIDS; POLYMORPHISM, GENETIC; PROTEIN STRUCTURE, TERTIARY; RECQ HELICASES; TRANSFECTION; VARIATION (GENETICS);

ESCHERICHIA COLI;

EID: 11244258888     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M407128200     Document Type: Article

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