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Volumn 52, Issue 4, 2004, Pages 516-523

The Effects of MK-0677, an Oral Growth Hormone Secretagogue, in Patients with Hip Fracture

(17)  Bach, Mark A a   Rockwood, Kenneth b,n   Zetterberg, Carl c   Thamsborg, Gorm d   Hébert, Réjean e   Devogelaer, Jean Pierre f   Christiansen, Jens Sandahl g   Rizzoli, René h   Ochsner, J Lockwood i   Beisaw, Norman j   Gluck, Oscar k   Yu, Leisure l   Schwab, Thomas m   Farrington, Jeanne a   Taylor, Alice M a   Ng, Jennifer a   Fuh, Vivian b  


Author keywords

Hip fracture; MK 0677; Oral growth hormone secretagogue

Indexed keywords

GROWTH HORMONE SECRETAGOGUE; IBUTAMOREN; PLACEBO; SOMATOMEDIN C;

EID: 11144357003     PISSN: 00028614     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1532-5415.2004.52156.x     Document Type: Article
Times cited : (75)

References (43)
  • 1
    • 0031911453 scopus 로고    scopus 로고
    • Hip fracture in the elderly
    • Ethans KD, MacKnight C. Hip fracture in the elderly. Postgrad Med 1998;103:157-170.
    • (1998) Postgrad Med , vol.103 , pp. 157-170
    • Ethans, K.D.1    MacKnight, C.2
  • 2
    • 0026667691 scopus 로고
    • Decline in physical function following hip fracture
    • Marottoli R, Berkman L, Cooney L. Decline in physical function following hip fracture. J Am Geriatr Soc 1992;40:861-866.
    • (1992) J Am Geriatr Soc , vol.40 , pp. 861-866
    • Marottoli, R.1    Berkman, L.2    Cooney, L.3
  • 3
    • 0029887854 scopus 로고    scopus 로고
    • Clinical outcomes and mortality after hip fracture: A two-year follow-up study
    • Baudois C, Fardellone P, Bean K et al. Clinical outcomes and mortality after hip fracture: A two-year follow-up study. Bone 1996;18:149S-157S.
    • (1996) Bone , vol.18
    • Baudois, C.1    Fardellone, P.2    Bean, K.3
  • 4
    • 0025369435 scopus 로고
    • Predictors of functional recovery 1 year following hospital discharge for hip fracture: A prospective study
    • Magaziner J, Simonsick EM, Hashner TM et al. Predictors of functional recovery 1 year following hospital discharge for hip fracture: A prospective study. J Gerontol 1990;45:M101-M107.
    • (1990) J Gerontol , vol.45
    • Magaziner, J.1    Simonsick, E.M.2    Hashner, T.M.3
  • 5
    • 0036799693 scopus 로고    scopus 로고
    • Mortality, disability and nursing home use for persons with and without hip fracture: A population-based study
    • Leibson CL, Tosteson ANA, Gabriel SE et al. Mortality, disability and nursing home use for persons with and without hip fracture: A population-based study. J Am Geriatr Soc 2002;50:1644-1650.
    • (2002) J Am Geriatr Soc , vol.50 , pp. 1644-1650
    • Leibson, C.L.1    Tosteson, A.N.A.2    Gabriel, S.E.3
  • 6
    • 0031053314 scopus 로고    scopus 로고
    • Outcomes and costs after hip fracture and stroke: A comparison of rehabilitation settings
    • Kramer AM, Steiner JF, Schlenker RE. Outcomes and costs after hip fracture and stroke: A comparison of rehabilitation settings. JAMA 1997;277:396-404.
    • (1997) JAMA , vol.277 , pp. 396-404
    • Kramer, A.M.1    Steiner, J.F.2    Schlenker, R.E.3
  • 7
    • 0029838926 scopus 로고    scopus 로고
    • Self-report of difficulty in performing functional activities identifies a broad range of disability in old age
    • Langlois JA, Maggi S, Harris T. Self-report of difficulty in performing functional activities identifies a broad range of disability in old age. J Am Geriatr Soc 1996;44:1421-1428.
    • (1996) J Am Geriatr Soc , vol.44 , pp. 1421-1428
    • Langlois, J.A.1    Maggi, S.2    Harris, T.3
  • 9
    • 0021928693 scopus 로고
    • The influence of age on the 24-hour integrated concentration of growth hormone in normal individuals
    • Zadik Z, Chalew SA, McCarter RJ Jr et al. The influence of age on the 24-hour integrated concentration of growth hormone in normal individuals. J Clin Endocrinol Metab 1985;60:513-516.
    • (1985) J Clin Endocrinol Metab , vol.60 , pp. 513-516
    • Zadik, Z.1    Chalew, S.A.2    McCarter Jr., R.J.3
  • 10
    • 0030696043 scopus 로고    scopus 로고
    • Muscle fiber atrophy and degeneration induced by experimental immobility and hindlimb suspension
    • Nonaka I, Miyazawa M, Sukegawa T et al. Muscle fiber atrophy and degeneration induced by experimental immobility and hindlimb suspension. Int J Sports Med 1997;18(Suppl 4):S292-S294.
    • (1997) Int J Sports Med , vol.18 , Issue.SUPPL. 4
    • Nonaka, I.1    Miyazawa, M.2    Sukegawa, T.3
  • 11
    • 0025368959 scopus 로고
    • Effects of human growth hormone in men over 60 years old
    • Rudman D, Feller A, Nagraj H et al. Effects of human growth hormone in men over 60 years old. N Engl J Med 1990;323:1-6.
    • (1990) N Engl J Med , vol.323 , pp. 1-6
    • Rudman, D.1    Feller, A.2    Nagraj, H.3
  • 12
    • 0034877764 scopus 로고    scopus 로고
    • Growth hormone administration and exercise effects on muscle fibre type and diameter in moderately frail older people
    • Hennessey JV, Chromiak JA, Dellaventuras S et al. Growth hormone administration and exercise effects on muscle fibre type and diameter in moderately frail older people. J Am Geriatr Soc 2001;49:852-858.
    • (2001) J Am Geriatr Soc , vol.49 , pp. 852-858
    • Hennessey, J.V.1    Chromiak, J.A.2    Dellaventuras, S.3
  • 13
    • 0036558620 scopus 로고    scopus 로고
    • Anabolic agents in frail elderly patients
    • Hubbard R, Pierce A. Anabolic agents in frail elderly patients. Rev Clin Gerontol 2002;12:145-158.
    • (2002) Rev Clin Gerontol , vol.12 , pp. 145-158
    • Hubbard, R.1    Pierce, A.2
  • 14
    • 0033669036 scopus 로고    scopus 로고
    • Use of human GH in elderly patients with accidental hip fracture
    • Van der Lely AJ, Lanberts SW, Janch KW et al. Use of human GH in elderly patients with accidental hip fracture. Eur J Endocrinol 2000;143:585-592.
    • (2000) Eur J Endocrinol , vol.143 , pp. 585-592
    • Van Der Lely, A.J.1    Lanberts, S.W.2    Janch, K.W.3
  • 15
    • 0029129652 scopus 로고
    • Design and biological activities of L-163,191 (MK-0677): A potent, orally active growth hormone secretagogue
    • Patchett AA, Nargund RP, Tata JR et al. Design and biological activities of L-163,191 (MK-0677): A potent, orally active growth hormone secretagogue. Proc Natl Acad Sci U S A 1995;92:7001-7005.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7001-7005
    • Patchett, A.A.1    Nargund, R.P.2    Tata, J.R.3
  • 16
    • 0016823810 scopus 로고
    • 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 17
    • 0028127912 scopus 로고
    • The Sickness Impact Profile for Nursing Homes (SIP-NH)
    • Gerety MB, Cornell JE, Mulrow CD et al. The Sickness Impact Profile for Nursing Homes (SIP-NH). J Gerontol 1994;49:M2-M8.
    • (1994) J Gerontol , vol.49
    • Gerety, M.B.1    Cornell, J.E.2    Mulrow, C.D.3
  • 18
    • 0030045919 scopus 로고    scopus 로고
    • A portable neuromuscular function assessment for studying recovery from hip fracture
    • Fox KM, Felsenthal G, Hebel JR et al. A portable neuromuscular function assessment for studying recovery from hip fracture. Arch Phys Med Rehab 1998;77:171-176.
    • (1998) Arch Phys Med Rehab , vol.77 , pp. 171-176
    • Fox, K.M.1    Felsenthal, G.2    Hebel, J.R.3
  • 19
    • 0028292936 scopus 로고
    • A short physical performance battery assessing lower extremity function. Association with self-reported disability and prediction of mortality and nursing home admission
    • Guralnik J, Simonsick EM, Ferrucci L et al. A short physical performance battery assessing lower extremity function. Association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994;49:M85-M94.
    • (1994) J Gerontol , vol.49
    • Guralnik, J.1    Simonsick, E.M.2    Ferrucci, L.3
  • 20
    • 0018868636 scopus 로고
    • Functional Status Index. Reliability of a chronic disease evaluation instrument
    • Jette AM. Functional Status Index. Reliability of a chronic disease evaluation instrument. Arch Phys Med Rehabil 1980;61:395-401.
    • (1980) Arch Phys Med Rehabil , vol.61 , pp. 395-401
    • Jette, A.M.1
  • 21
    • 0025221728 scopus 로고
    • An objective measure of physical function of elderly outpatients
    • Reuben DB, Siu AL. An objective measure of physical function of elderly outpatients. J Am Geriatr Soc 1990;38:1105-1112.
    • (1990) J Am Geriatr Soc , vol.38 , pp. 1105-1112
    • Reuben, D.B.1    Siu, A.L.2
  • 22
    • 18744371534 scopus 로고    scopus 로고
    • Effects of exercise training on frailty in community-dwelling older adults: Results of a randomized, controlled trial
    • Binder EF, Schechtman KB, Ehsani AA. Effects of exercise training on frailty in community-dwelling older adults: Results of a randomized, controlled trial. J Am Geriatr Soc 2002;50:1921-1928.
    • (2002) J Am Geriatr Soc , vol.50 , pp. 1921-1928
    • Binder, E.F.1    Schechtman, K.B.2    Ehsani, A.A.3
  • 23
    • 0021666221 scopus 로고
    • Procedures for comparing samples with multiple endpoints
    • O'Brien P. Procedures for comparing samples with multiple endpoints. Biometrics 1984;40:1079-1087.
    • (1984) Biometrics , vol.40 , pp. 1079-1087
    • O'Brien, P.1
  • 25
    • 0027501816 scopus 로고
    • The use of Goal Attainment Scaling in measuring clinically important change in the frail elderly
    • Rockwood K, Stolee P, Fox RA. The use of Goal Attainment Scaling in measuring clinically important change in the frail elderly. J Clin Epidemiol 1993;46:1113-1118.
    • (1993) J Clin Epidemiol , vol.46 , pp. 1113-1118
    • Rockwood, K.1    Stolee, P.2    Fox, R.A.3
  • 26
    • 0032188735 scopus 로고    scopus 로고
    • Testing the measurement properties of the Short Form-36 in a frail elderly population
    • Stadnyk K, Calder J, Rockwood K. Testing the measurement properties of the Short Form-36 in a frail elderly population. J Clin Epidemiol 1998;51:827-835.
    • (1998) J Clin Epidemiol , vol.51 , pp. 827-835
    • Stadnyk, K.1    Calder, J.2    Rockwood, K.3
  • 27
    • 0033921384 scopus 로고    scopus 로고
    • Reliability, validity and responsiveness of the lower extremity measure for patients with a hip fracture
    • Jaglal S. Lakhaniz, Schatzker J. Reliability, validity and responsiveness of the lower extremity measure for patients with a hip fracture. J Bone Joint Surg 2000;82-A:955-962.
    • (2000) J Bone Joint Surg , vol.82 A , pp. 955-962
    • Jaglal, S.1    Lakhaniz2    Schatzker, J.3
  • 28
    • 0036317130 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, randomized clinical trial of recombinant human chorionic gonadotropin on muscle strength and physical function and activity in older men with partial age-related androgen deficiency
    • Liu PY, Wihsart SM, Handelsman DJ. A double-blind, placebo-controlled, randomized clinical trial of recombinant human chorionic gonadotropin on muscle strength and physical function and activity in older men with partial age-related androgen deficiency. J Clin Endocrinol Metab 2002;87:3125-3135.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3125-3135
    • Liu, P.Y.1    Wihsart, S.M.2    Handelsman, D.J.3
  • 29
    • 0034080165 scopus 로고    scopus 로고
    • Delirium is independently associated with poor functional recovery after hip fracture
    • Marcantonio ER, Flacker JM, Michaels M et al. Delirium is independently associated with poor functional recovery after hip fracture. J Am Geriatr Soc 2000;48:618-624.
    • (2000) J Am Geriatr Soc , vol.48 , pp. 618-624
    • Marcantonio, E.R.1    Flacker, J.M.2    Michaels, M.3
  • 30
    • 0037773492 scopus 로고    scopus 로고
    • The epidemiology of delirium
    • Lindesay J, Rockwood K, MacDonald A, eds. Oxford: Oxford University Press
    • Lindesay J, Rockwood K, Rolfson D. The epidemiology of delirium. In: Lindesay J, Rockwood K, MacDonald A, eds. Delirium in Old Age. Oxford: Oxford University Press, 2002, pp 27-50.
    • (2002) Delirium in Old Age , pp. 27-50
    • Lindesay, J.1    Rockwood, K.2    Rolfson, D.3
  • 32
    • 0024472036 scopus 로고
    • Hip fractures in the elderly. Mortality, functional results and social readaptation
    • Broos PLO, Van Haaften KIK, Stappaerts KH et al. Hip fractures in the elderly. Mortality, functional results and social readaptation. Int Surg 1989;74:191-194.
    • (1989) Int Surg , vol.74 , pp. 191-194
    • Broos, P.L.O.1    Van Haaften, K.I.K.2    Stappaerts, K.H.3
  • 33
    • 0031975384 scopus 로고    scopus 로고
    • Paracrine/autocrine regulation of breast cancer by the insulin-like growth factors
    • Rasmussen AA, Cullen KJ. Paracrine/autocrine regulation of breast cancer by the insulin-like growth factors. Breast Cancer Res Treat 1998;47:219-233.
    • (1998) Breast Cancer Res Treat , vol.47 , pp. 219-233
    • Rasmussen, A.A.1    Cullen, K.J.2
  • 34
    • 0031965185 scopus 로고    scopus 로고
    • The insulin-like growth factors and breast cancer-revisited
    • Yee D. The insulin-like growth factors and breast cancer-revisited. Breast Cancer Res Treat 1998;47:197-199.
    • (1998) Breast Cancer Res Treat , vol.47 , pp. 197-199
    • Yee, D.1
  • 35
    • 0031985633 scopus 로고    scopus 로고
    • Type I insulin-like growth factor receptor function in breast cancer
    • Surmacz E, Guvakova MA, Nolan MK et al. Type I insulin-like growth factor receptor function in breast cancer. Breast Cancer Res Treat 1998; 47:255-267.
    • (1998) Breast Cancer Res Treat , vol.47 , pp. 255-267
    • Surmacz, E.1    Guvakova, M.A.2    Nolan, M.K.3
  • 36
    • 0031964262 scopus 로고    scopus 로고
    • The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene
    • Oates AJ, Schumaker LM, Jenkins SB et al. The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene. Breast Cancer Res Treat 1998;47:269-281.
    • (1998) Breast Cancer Res Treat , vol.47 , pp. 269-281
    • Oates, A.J.1    Schumaker, L.M.2    Jenkins, S.B.3
  • 37
    • 0031984805 scopus 로고    scopus 로고
    • Reduction of ventral prostate weight by finasteride is associated with suppression of insulin-like growth factor I (IGF-I) and IGF-I receptor genes and with an increase in IGF binding protein 3
    • Huynh H, Seyam RM, Brock GB. Reduction of ventral prostate weight by finasteride is associated with suppression of insulin-like growth factor I (IGF-I) and IGF-I receptor genes and with an increase in IGF binding protein 3. Cancer Res 1998;58:215-218.
    • (1998) Cancer Res , vol.58 , pp. 215-218
    • Huynh, H.1    Seyam, R.M.2    Brock, G.B.3
  • 38
    • 0026559830 scopus 로고
    • Hip fractures in geriatric patients. Results of an interdisciplinary hospital care program
    • Zuckerman JD, Sakales SR, Fahian DR et al. Hip fractures in geriatric patients. Results of an interdisciplinary hospital care program. Clin Orthoped Rel Res 1992;274:213-225.
    • (1992) Clin Orthoped Rel Res , vol.274 , pp. 213-225
    • Zuckerman, J.D.1    Sakales, S.R.2    Fahian, D.R.3
  • 39
    • 0027353115 scopus 로고
    • Elderly patients with hip fractures. Improved outcome with the use of care maps with high-quality medical and nursing protocols
    • Ogilvie-Harris DJ, Botsford DJ, Hawker RW. Elderly patients with hip fractures. Improved outcome with the use of care maps with high-quality medical and nursing protocols. J Orthop Trauma 1993;7:428-437.
    • (1993) J Orthop Trauma , vol.7 , pp. 428-437
    • Ogilvie-Harris, D.J.1    Botsford, D.J.2    Hawker, R.W.3
  • 41
    • 0032524767 scopus 로고    scopus 로고
    • Protein supplements increase serum insulin-like growth factor-I levels and attenuate proximal femur bone loss in patients with recent hip fracture
    • Schurch MA. Protein supplements increase serum insulin-like growth factor-I levels and attenuate proximal femur bone loss in patients with recent hip fracture. Ann Intern Med 1998;128:801-809.
    • (1998) Ann Intern Med , vol.128 , pp. 801-809
    • Schurch, M.A.1
  • 42
    • 0033755289 scopus 로고    scopus 로고
    • Conceptualization and measurement of frailty in elderly people
    • Rockwood K, Hogan HB, MacKnight C. Conceptualization and measurement of frailty in elderly people. Drugs Aging 2000;17:295-302.
    • (2000) Drugs Aging , vol.17 , pp. 295-302
    • Rockwood, K.1    Hogan, H.B.2    MacKnight, C.3
  • 43
    • 0034533408 scopus 로고    scopus 로고
    • Rasch analysis of the hierarchical assessment of balance and mobility (HABAM)
    • MacKnight C, Rockwood K. Rasch analysis of the hierarchical assessment of balance and mobility (HABAM). J Clin Epidemiol 2000;53:1242-1247.
    • (2000) J Clin Epidemiol , vol.53 , pp. 1242-1247
    • MacKnight, C.1    Rockwood, K.2


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