N-Alkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, μ and δ opioid agonists: A μ address

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 9, 2004, Pages 2113-2116

  Carson, John R ^a   Coats, Steven J ^a   Codd, Ellen E ^a   Dax, Scott L ^a   Lee, Jung ^a   Martinez, Rebecca P ^a   McKown, Linda A ^a   Neilson, Lou Anne ^a,b   Pitis, Philip M ^a   Wu, Wu Nan ^a   Zhang, Sui Po ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; ANTINOCICEPTIVE AGENT; BENZAMIDE DERIVATIVE; DELTA OPIATE RECEPTOR AGONIST; MU OPIATE RECEPTOR AGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANALGESICS; BENZAMIDES; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; STRUCTURE-ACTIVITY RELATIONSHIP;

STAPHYLOCOCCUS PHAGE 3A;

EID: 11144355577     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.052     Document Type: Article

References (18)

1. Rapaka R.S., Porreca F. Pharm. Res. 8:1991;1.
2. Coop A., Rice K.C. Drug News Perspect. 13:2000;481.
3. Calderone S.N., Rice K.C., Rothman R.B., Dondio G., Ronzoni S., Farina C., Graziani D., Parini C., Petrillo P., Giardina G.A.M. Farmaco. 56:2001;117.
4. Broom D.C., Jutkiewicz E.M., Rice K.C., Traynor J.R., Woods J.H. Jpn. J. Pharmacol. 90:2002;1.
5. Hudzik T.J., Howell A., Payza K., Cross A.J. Eur. J. Pharmacol. 396:2000;101.
6. Schreiber G., Campa M.J., Prabhakar S., O'Briant K., Bepler G., Patz E.F. Jr. Anticancer Res. 18:1998;1787.
7. Vaught Jeffry L., Takemori A.E. J. Pharmacol. Exp. Ther. 208:1979;86.
8. Heyman J.S., Vaught J.L., Mosberg H.I., Haaseth R.C., Porreca F. Eur. J. Pharmacol. 165:1989;1.
9. Su Y.-F., McNutt R.W., Chang K.-J. J. Pharmacol. Exp. Ther. 287:1998;815.
10. Bishop M.J., Garrido D.M., Boswell G.E., Collins M.A., Harris P.A., McNutt R.W., O'Neill S.J., Wei K., Chang K.-J. J. Med. Chem. 46:2003;623.
11. Glass P.S.A., Chavis I., Ginsberg B., Gan T.J., Greenberg B.D. Anesthesiology. 91(Suppl.):1999;. abstr. 985.
12. Carson, J. R.; Coates, S. J.; Codd, E. E.; Dax, S. L.; Lee, J.; Martinez, R. P.; Neilson, L. A.; Pitis, P. M.; Zhang, S.-P. Bioorg. Med. Chem. Lett. 2004, 14, preceding paper. doi: 10.1016/j.bmcl.2004.02.051.
13. Eddy N.B., Leimbach D. J. Pharmacol. Exp. Ther. 103:1953;74.
14. Wu W.-N., McKown L.A., Yorgey K.A., Pritchard J.F. J. Pharm. Biomed. Anal. 20:1999;687.
15. Carson, J. R.; Coats, S. J.; Neilson, L. A.; Wu, W.-N.; Boyd, R. E.; Pitis, P. M. World Patent Application WO 0166543 A2, 2001; Chem. Abstr. 2001, 135, 242144.
16. Portoghese P.S., Sultana M., Nagase H., Takemori A.E. J. Med. Chem. 31:1988;281.
17. Dondio G., Ronzoni S., Petrillo P. Exp. Opin. Ther. Pat. 7:1997;1075.
18. Varga E.V., Li X., Stropova D., Zalewska T., Landsman R.S., Knapp R.J., Malatynska E., Kawai K., Mizusura A., Nagase H., Calderon S.N., Rice K., Hruby V.J., Roeske W.R., Yamamura H.I. Mol. Pharmacol. 50:1996;1619.