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Volumn 22, Issue 3, 2004, Pages 465-471

Bisphosphonate treatment affects trabecular bone apparent modulus through micro-architecture rather than matrix properties

Author keywords

Bisphosphonates; Bone matrix mineralization; Bone micro architecture; Mechanical properties; Osteoporosis

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; RISEDRONIC ACID;

EID: 11144353705     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.orthres.2003.05.001     Document Type: Article
Times cited : (61)

References (44)
  • 1
    • 0027139913 scopus 로고
    • The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates
    • Balena R. Toolan B.C. Shea M. Markatos A. Myers E.R. Lee S.C. et al. The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates J. Clin. Invest. 92 1993 2577-2586
    • (1993) J. Clin. Invest. , vol.92 , pp. 2577-2586
    • Balena, R.1    Toolan, B.C.2    Shea, M.3    Markatos, A.4    Myers, E.R.5    Lee, S.C.6
  • 2
    • 0004851872 scopus 로고    scopus 로고
    • Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures
    • Black D.M. Cummings S.R. Karpf D.B. Cauley J.A. Thompson D.E. Nevitt M.C. et al. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures Fracture Intervention Trial Research Group Lancet 348 1996 1535-1541
    • (1996) Lancet , vol.348 , pp. 1535-1541
    • Black, D.M.1    Cummings, S.R.2    Karpf, D.B.3    Cauley, J.A.4    Thompson, D.E.5    Nevitt, M.C.6
  • 3
    • 0033755981 scopus 로고    scopus 로고
    • Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women
    • Boivin G.Y. Chavassieux P.M. Santora A.C. Yates J. Meunier P.J. Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women Bone 27 2000 687-694
    • (2000) Bone , vol.27 , pp. 687-694
    • Boivin, G.Y.1    Chavassieux, P.M.2    Santora, A.C.3    Yates, J.4    Meunier, P.J.5
  • 4
    • 0021960062 scopus 로고
    • Bone remodelling in response to in vivo fatigue microdamage
    • Burr D.B. Martin R.B. Schaffler M.B. Radin E.L. Bone remodelling in response to in vivo fatigue microdamage J. Biomech. 18 1985 189-200
    • (1985) J. Biomech. , vol.18 , pp. 189-200
    • Burr, D.B.1    Martin, R.B.2    Schaffler, M.B.3    Radin, E.L.4
  • 6
    • 0030868816 scopus 로고    scopus 로고
    • Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodelling in patients with osteoporosis
    • Chavassieux P.M. Arlot M.E. Reda C. Wei L. Yates A.J. Meunier P.J. Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodelling in patients with osteoporosis J. Clin. Invest. 100 1997 1475-1480
    • (1997) J. Clin. Invest. , vol.100 , pp. 1475-1480
    • Chavassieux, P.M.1    Arlot, M.E.2    Reda, C.3    Wei, L.4    Yates, A.J.5    Meunier, P.J.6
  • 7
    • 0035847609 scopus 로고    scopus 로고
    • Risedronate: A clinical review
    • Crandall C. Risedronate: a clinical review Arch. Intern. Med. 161 2001 353-360
    • (2001) Arch. Intern. Med. , vol.161 , pp. 353-360
    • Crandall, C.1
  • 8
    • 0021761489 scopus 로고
    • Effects of differences in mineralization on the mechanical properties of bone
    • Currey J.D. Effects of differences in mineralization on the mechanical properties of bone Philos. Trans. R. Soc. Lond. B. Biol. Sci. 304 1984 509-518
    • (1984) Philos. Trans. R. Soc. Lond. B. Biol. Sci. , vol.304 , pp. 509-518
    • Currey, J.D.1
  • 9
    • 0034873889 scopus 로고    scopus 로고
    • A decreased subchondral trabecular bone tissue elastic modulus is associated with pre-arthritic cartilage damage
    • Day J.S. Ding M. van der Linden J.C. Hvid I. Sumner D.R. Weinans H. A decreased subchondral trabecular bone tissue elastic modulus is associated with pre-arthritic cartilage damage J. Orthop. Res. 19 2001 914-918
    • (2001) J. Orthop. Res. , vol.19 , pp. 914-918
    • Day, J.S.1    Ding, M.2    van der Linden, J.C.3    Hvid, I.4    Sumner, D.R.5    Weinans, H.6
  • 10
    • 0034080243 scopus 로고    scopus 로고
    • How does antiresorptive therapy decrease the risk of fracture in women with osteoporosis?
    • Delmas P.D. How does antiresorptive therapy decrease the risk of fracture in women with osteoporosis? Bone 27 2000 1-3
    • (2000) Bone , vol.27 , pp. 1-3
    • Delmas, P.D.1
  • 11
    • 0043268864 scopus 로고    scopus 로고
    • Canine cancellous bone microarchitecture after one year of high-dose bisphosphonates
    • Ding M. Day J.S. Burr D.B. Mashiba T. Hirano T. Weinans H. et al. Canine cancellous bone microarchitecture after one year of high-dose bisphosphonates Calcif. Tissue Int. 72 2003 737-744
    • (2003) Calcif. Tissue Int. , vol.72 , pp. 737-744
    • Ding, M.1    Day, J.S.2    Burr, D.B.3    Mashiba, T.4    Hirano, T.5    Weinans, H.6
  • 12
    • 0033105205 scopus 로고    scopus 로고
    • Accuracy of cancellous bone volume fraction measured by micro-CT scanning
    • Ding M. Odgaard A. Hvid I. Accuracy of cancellous bone volume fraction measured by micro-CT scanning J. Biomech. 32 1999 323-326
    • (1999) J. Biomech. , vol.32 , pp. 323-326
    • Ding, M.1    Odgaard, A.2    Hvid, I.3
  • 13
    • 0026029338 scopus 로고
    • Osteopenia, hematopoiesis, and bone remodelling in iliac crest and femoral biopsies: A prospective study of 102 cases of femoral neck fractures
    • Eventov I. Frisch B. Cohen Z. Hammel I. Osteopenia, hematopoiesis, and bone remodelling in iliac crest and femoral biopsies: a prospective study of 102 cases of femoral neck fractures Bone 12 1991 1-6
    • (1991) Bone , vol.12 , pp. 1-6
    • Eventov, I.1    Frisch, B.2    Cohen, Z.3    Hammel, I.4
  • 14
    • 0033552255 scopus 로고    scopus 로고
    • Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: A randomized controlled trial
    • Vertebral Efficacy With Risedronate Therapy (VERT) Study Group
    • Harris S.T. Watts N.B. Genant H.K. McKeever C.D. Hangartner T. Keller M. et al. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial Vertebral Efficacy With Risedronate Therapy (VERT) Study Group Jama 282 1999 1344-1352
    • (1999) Jama , vol.282 , pp. 1344-1352
    • Harris, S.T.1    Watts, N.B.2    Genant, H.K.3    McKeever, C.D.4    Hangartner, T.5    Keller, M.6
  • 15
    • 0027939940 scopus 로고
    • The bone-remodelling transient: Implications for the interpretation of clinical studies of bone mass change
    • Heaney R.P. The bone-remodelling transient: implications for the interpretation of clinical studies of bone mass change J. Bone Miner. Res. 9 1994 1515-1523
    • (1994) J. Bone Miner. Res. , vol.9 , pp. 1515-1523
    • Heaney, R.P.1
  • 16
    • 0034081467 scopus 로고    scopus 로고
    • Does suppression of bone turnover impair mechanical properties by allowing microdamage accumulation?
    • Hirano T. Turner C.H. Forwood M.R. Johnston C.C. Burr D.B. Does suppression of bone turnover impair mechanical properties by allowing microdamage accumulation? Bone 27 2000 13-20
    • (2000) Bone , vol.27 , pp. 13-20
    • Hirano, T.1    Turner, C.H.2    Forwood, M.R.3    Johnston, C.C.4    Burr, D.B.5
  • 17
    • 0032855086 scopus 로고    scopus 로고
    • NACOB presentation to ASB Young Scientist Award: Postdoctoral. The impact of boundary conditions and mesh size on the accuracy of cancellous bone tissue modulus determination using large-scale finite-element modeling
    • Jacobs C.R. Davis B.R. Rieger C.J. Francis J.J. Saad M. Fyhrie D.P. NACOB presentation to ASB Young Scientist Award: Postdoctoral. The impact of boundary conditions and mesh size on the accuracy of cancellous bone tissue modulus determination using large-scale finite-element modeling North American Congress on Biomechanics J. Biomech. 32 1999 1159-1164
    • (1999) J. Biomech. , vol.32 , pp. 1159-1164
    • Jacobs, C.R.1    Davis, B.R.2    Rieger, C.J.3    Francis, J.J.4    Saad, M.5    Fyhrie, D.P.6
  • 18
    • 0033061143 scopus 로고    scopus 로고
    • The role of an effective isotropic tissue modulus in the elastic properties of cancellous bone
    • Kabel J. van Rietbergen B. Dalstra M. Odgaard A. Huiskes R. The role of an effective isotropic tissue modulus in the elastic properties of cancellous bone J. Biomech. 32 1999 673-680
    • (1999) J. Biomech. , vol.32 , pp. 673-680
    • Kabel, J.1    van Rietbergen, B.2    Dalstra, M.3    Odgaard, A.4    Huiskes, R.5
  • 21
    • 0032191127 scopus 로고    scopus 로고
    • Numerical errors and uncertainties in finite-element modeling of trabecular bone
    • Ladd A.J. Kinney J.H. Numerical errors and uncertainties in finite-element modeling of trabecular bone J. Biomech. 31 1998 941-945
    • (1998) J. Biomech. , vol.31 , pp. 941-945
    • Ladd, A.J.1    Kinney, J.H.2
  • 22
    • 0032171053 scopus 로고    scopus 로고
    • Finite-element modeling of trabecular bone: Comparison with mechanical testing and determination of tissue modulus
    • Ladd A.J. Kinney J.H. Haupt D.L. Goldstein S.A. Finite-element modeling of trabecular bone: comparison with mechanical testing and determination of tissue modulus J. Orthop. Res. 16 1998 622-628
    • (1998) J. Orthop. Res. , vol.16 , pp. 622-628
    • Ladd, A.J.1    Kinney, J.H.2    Haupt, D.L.3    Goldstein, S.A.4
  • 23
    • 0024411207 scopus 로고
    • The effect of constraint on the mechanical behaviour of trabecular bone specimens
    • Linde F. Hvid I. The effect of constraint on the mechanical behaviour of trabecular bone specimens J. Biomech. 22 1989 485-490
    • (1989) J. Biomech. , vol.22 , pp. 485-490
    • Linde, F.1    Hvid, I.2
  • 24
    • 0034065559 scopus 로고    scopus 로고
    • Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib
    • Mashiba T. Hirano T. Turner C.H. Forwood M.R. Johnston C.C. Burr D.B. Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib J. Bone Miner. Res. 15 2000 613-620
    • (2000) J. Bone Miner. Res. , vol.15 , pp. 613-620
    • Mashiba, T.1    Hirano, T.2    Turner, C.H.3    Forwood, M.R.4    Johnston, C.C.5    Burr, D.B.6
  • 25
    • 0035004850 scopus 로고    scopus 로고
    • Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles
    • Mashiba T. Turner C.H. Hirano T. Forwood M.R. Johnston C.C. Burr D.B. Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles Bone 28 2001 524-531
    • (2001) Bone , vol.28 , pp. 524-531
    • Mashiba, T.1    Turner, C.H.2    Hirano, T.3    Forwood, M.R.4    Johnston, C.C.5    Burr, D.B.6
  • 26
    • 0029854140 scopus 로고    scopus 로고
    • Current bone mineral density data on bisphosphonates in postmenopausal osteoporosis
    • McClung M.R. Current bone mineral density data on bisphosphonates in postmenopausal osteoporosis Bone 19 1996 195S-198S
    • (1996) Bone , vol.19
    • McClung, M.R.1
  • 27
    • 0030678552 scopus 로고    scopus 로고
    • Bone mineral density reflects bone mass but also the degree of mineralization of bone: Therapeutic implications
    • Meunier P.J. Boivin G. Bone mineral density reflects bone mass but also the degree of mineralization of bone: therapeutic implications Bone 21 1997 373-377
    • (1997) Bone , vol.21 , pp. 373-377
    • Meunier, P.J.1    Boivin, G.2
  • 28
    • 0032851002 scopus 로고    scopus 로고
    • Intermittent and continuous administration of the bisphosphonate ibandronate in ovariohysterectomized beagle dogs: Effects on bone morphometry and mineral properties
    • Monier-Faugere M.C. Geng Z. Paschalis E.P. Qi Q. Arnala I. Bauss F. et al. Intermittent and continuous administration of the bisphosphonate ibandronate in ovariohysterectomized beagle dogs: effects on bone morphometry and mineral properties J. Bone Miner. Res. 14 1999 1768-1778
    • (1999) J. Bone Miner. Res. , vol.14 , pp. 1768-1778
    • Monier-Faugere, M.C.1    Geng, Z.2    Paschalis, E.P.3    Qi, Q.4    Arnala, I.5    Bauss, F.6
  • 29
    • 0027462103 scopus 로고
    • Increased intracortical remodelling following fatigue damage
    • Mori S. Burr D.B. Increased intracortical remodelling following fatigue damage Bone 14 1993 103-109
    • (1993) Bone , vol.14 , pp. 103-109
    • Mori, S.1    Burr, D.B.2
  • 30
    • 0033294444 scopus 로고    scopus 로고
    • Convergence behavior of high-resolution finite element models of trabecular bone
    • Niebur G.L. Yuen J.C. Hsia A.C. Keaveny T.M. Convergence behavior of high-resolution finite element models of trabecular bone J. Biomech. Eng. 121 1999 629-635
    • (1999) J. Biomech. Eng. , vol.121 , pp. 629-635
    • Niebur, G.L.1    Yuen, J.C.2    Hsia, A.C.3    Keaveny, T.M.4
  • 31
    • 0002206113 scopus 로고
    • The composition, structure and remodelling of bone: A basis for interpretation of bone mineral measurements
    • J. Dequeker, P. Geusens, & H. W. Wahner (Eds.), Leuven: Leuven University Press
    • Parfitt A.M. The composition, structure and remodelling of bone: a basis for interpretation of bone mineral measurements, in: Dequeker J. Geusens P. Wahner H.W. (Eds.), Bone mineral measurement by photon absorptiometry 1988 Leuven University Press Leuven
    • (1988) Bone Mineral Measurement By Photon Absorptiometry
    • Parfitt, A.M.1
  • 32
    • 0033119284 scopus 로고    scopus 로고
    • Elastic properties of microstructural components of human bone tissue as measured by nanoindentation
    • Rho J.Y. Roy II M.E. Tsui T.Y. Pharr G.M. Elastic properties of microstructural components of human bone tissue as measured by nanoindentation J. Biomed. Mater. Res. 45 1999 48-54
    • (1999) J. Biomed. Mater. Res. , vol.45 , pp. 48-54
    • Rho, J.Y.1    Roy II, M.E.2    Tsui, T.Y.3    Pharr, G.M.4
  • 33
    • 0029884643 scopus 로고    scopus 로고
    • Bisphosphonates: Mechanisms of action
    • Rodan G.A. Fleisch H.A. Bisphosphonates: mechanisms of action J. Clin. Invest. 97 1996 2692-2696
    • (1996) J. Clin. Invest. , vol.97 , pp. 2692-2696
    • Rodan, G.A.1    Fleisch, H.A.2
  • 34
    • 0031006173 scopus 로고    scopus 로고
    • Mineralization of cancellous bone after alendronate and sodium fluoride treatment: A quantitative backscattered electron imaging study on minipig ribs
    • Roschger P. Fratzl P. Klaushofer K. Rodan G. Mineralization of cancellous bone after alendronate and sodium fluoride treatment: a quantitative backscattered electron imaging study on minipig ribs Bone 20 1997 393-397
    • (1997) Bone , vol.20 , pp. 393-397
    • Roschger, P.1    Fratzl, P.2    Klaushofer, K.3    Rodan, G.4
  • 35
    • 0033065233 scopus 로고    scopus 로고
    • Bisphosphonates: From the laboratory to the clinic and back again
    • Russell R.G. Rogers M.J. Bisphosphonates: from the laboratory to the clinic and back again Bone 25 1999 97-106
    • (1999) Bone , vol.25 , pp. 97-106
    • Russell, R.G.1    Rogers, M.J.2
  • 36
    • 0033841239 scopus 로고    scopus 로고
    • Alendronate in the treatment of osteoporosis: A review of the clinical trials
    • Siris E. Alendronate in the treatment of osteoporosis: a review of the clinical trials J. Womens Health Gend. Based Med. 9 2000 599-606
    • (2000) J. Womens Health Gend. Based Med. , vol.9 , pp. 599-606
    • Siris, E.1
  • 37
    • 0033678399 scopus 로고    scopus 로고
    • Skeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic women. Phase III osteoporosis treatment study group
    • Tonino R.P. Meunier P.J. Emkey R. Rodriguez-Portales J.A. Menkes C.J. Wasnich R.D. et al. Skeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic women. Phase III osteoporosis treatment study group J. Clin. Endocrinol. Metab. 85 2000 3109-3115
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 3109-3115
    • Tonino, R.P.1    Meunier, P.J.2    Emkey, R.3    Rodriguez-Portales, J.A.4    Menkes, C.J.5    Wasnich, R.D.6
  • 39
    • 0032412757 scopus 로고    scopus 로고
    • Finite element analysis of trabecular bone structure: A comparison of image-based meshing techniques
    • Ulrich D. van Rietbergen B. Weinans H. Ruegsegger P. Finite element analysis of trabecular bone structure: a comparison of image-based meshing techniques J. Biomech. 31 1998 1187-1192
    • (1998) J. Biomech. , vol.31 , pp. 1187-1192
    • Ulrich, D.1    van Rietbergen, B.2    Weinans, H.3    Ruegsegger, P.4
  • 40
    • 0034763706 scopus 로고    scopus 로고
    • Trabecular bone's mechanical properties are affected by its nonuniform mineral distribution
    • Van Der Linden J.C. Birkenhager-Frenkel D.H. Verhaar J.A. Weinans H. Trabecular bone's mechanical properties are affected by its nonuniform mineral distribution J. Biomech. 34 2001 1573-1580
    • (2001) J. Biomech. , vol.34 , pp. 1573-1580
    • Van Der Linden, J.C.1    Birkenhager-Frenkel, D.H.2    Verhaar, J.A.3    Weinans, H.4
  • 41
    • 0028936206 scopus 로고
    • A new method to determine trabecular bone elastic properties and loading using micromechanical finite-element models
    • van Rietbergen B. Weinans H. Huiskes R. Odgaard A. A new method to determine trabecular bone elastic properties and loading using micromechanical finite-element models J. Biomech. 28 1995 69-81
    • (1995) J. Biomech. , vol.28 , pp. 69-81
    • van Rietbergen, B.1    Weinans, H.2    Huiskes, R.3    Odgaard, A.4
  • 42
    • 0033981552 scopus 로고    scopus 로고
    • Loss of osteocyte integrity in association with microdamage and bone remodelling after fatigue in vivo
    • Verborgt O. Gibson G.J. Schaffler M.B. Loss of osteocyte integrity in association with microdamage and bone remodelling after fatigue in vivo J. Bone Miner. Res. 15 2000 60-67
    • (2000) J. Bone Miner. Res. , vol.15 , pp. 60-67
    • Verborgt, O.1    Gibson, G.J.2    Schaffler, M.B.3
  • 44
    • 0035091321 scopus 로고    scopus 로고
    • Accumulation of in vivo fatigue microdamage and its relation to biomechanical properties in ageing human cortical bone
    • Zioupos P. Accumulation of in vivo fatigue microdamage and its relation to biomechanical properties in ageing human cortical bone J. Microsc. 201 2001 270-278
    • (2001) J. Microsc. , vol.201 , pp. 270-278
    • Zioupos, P.1


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