Splenic hamartoma with bizarre stromal cells

American Journal of Surgical Pathology

Volumn 29, Issue 1, 2005, Pages 109-114

  Wah, Cheuk ^a   Lee, Arthur K C ^b   Arora, Neeru ^c   Ben Arie, Yehudith ^d   Chan, John K C ^a  

^a QUEEN ELIZABETH HOSPITAL   (Hong Kong)

^b St Paul's Hospital Hong Kong   (Hong Kong)

^c INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^d RAMBAM MEDICAL CENTER   (Israel)

Author keywords

Bizarre stromal cells; Desmin; Immunohistochemistry; Myoid angioendothelioma; Spleen; Splenic hamartoma

Indexed keywords

FIBRIN;

ABDOMINAL PAIN; ADULT; ARTICLE; CASE REPORT; CHROMATIN; DENDRITIC CELL; FEMALE; HAMARTOMA; HEMANGIOENDOTHELIOMA; HISTIOCYTE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE; MALE; MELANOCYTE; MITOSIS; PLASMA CELL; SPLEEN HAMARTOMA; SPLEEN TUMOR; STROMA CELL;

ANTIGENS, CD; BIOLOGICAL MARKERS; FEMALE; HAMARTOMA; HUMANS; MALE; MIDDLE AGED; SPLENIC DISEASES; STROMAL CELLS; TREATMENT OUTCOME;

EID: 11144336534     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pas.0000146026.69082.68     Document Type: Article

References (38)

1. Abramowsky C, Alvarado C, Wyly JB, et al. 'Hamartoma' of the spleen (splenoma) in children. Pediatr Dev Pathol. 2004;7:231-236.
2. Arber DA, Strickler JG, Chen YY, et al. Splenic vascular rumors: a histologic, immunophenotypic, and virologic study. Am J Surg Pathol. 1997;21:827-835.
3. Beham A, Hermann W, Vennigerholz F, et al. Hamartoma of the spleen with haematological symptoms. Virchows Arch A Pathol Anat Histopathol. 1989;414:535-539.
4. Berge T. Splenoma. Acta Pathol Microbiol Scand. 1965;63:333-339.
5. Chang CF, Hwang SJ, Wu JC, et al. Hamartoma of spleen: a case report. Zhonghua Yi Xue Za Zhi (Taipei). 1991;48:388-392.
6. Clement PB. Multinucleated stromal giant cells of the uterine cervix. Arch Pathol Lab Med. 1985;109:200-202.
7. Compagno J, Hyams VJ, Lepore ML. Nasal polyposis with stromal atypia: review of follow-up study of 14 cases. Arch Pathol Lab Med. 1976;100: 224-226.
8. Dahl I. Ancient neurilemmoma (schwannoma). Acta Pathol Microbiol Scand. 1977;85:812-818.
9. Downes KA, Hart WR. Bizarre leiomyomas of the uterus: a comprehensive pathologic study of 24 cases with long-term follow-up. Am J Surg Pathol. 1997;21:1261-1270.
10. Elliott GB, Elliott JD. Superficial stromal reactions of lower genital tract. Arch Pathol. 1973;95:100-101.
11. Falk S, Stutte HJ. Hamartomas of the spleen: a study of 20 biopsy cases. Histopathology. 1989;14:603-612.
12. Ferguson ER, Sardi A, Beckman EN. Spontaneous rupture of splenic hamartoma. J La State Med Soc. 1993;145:48-52.
13. Fujii T, Obara T, Shudo R, et al. Splenic hamartoma associated with thrombocytopenia. J Gastroenterol. 1997;32:114-118.
14. Garvin DF, King FM. Cysts and nonlymphomatous tumors of the spleen. Pathol Annu. 1981;16:61-80.
15. Halevy A, Adam YG, Reif R, et al. Hamartoma of the spleen associated with thrombocytopenia mimicking gastric tumor. Int Surg. 1982;67:462-463.
16. Hayes TC, Britton HA, Mewborne EB, et al. Symptomatic splenic hamartoma: case report and literature review [Review]. Pediatrics. 1998; 101:E10.
17. Houston GD. The giant cell fibroma: a review of 464 cases. Oral Surg Oral Med Oral Pathol. 1982;53:582-587.
18. Iakovidou J, Panayiotides J, Papacharalambous X, et al. Splenic hamartoma: a case report. Eur J Surg Oncol. 1995;21:688-690.
19. Iozzo RV, Haas JE, Chard RL. Symptomatic splenic hemartoma: a report of two cases and review of the literature. Pediatrics. 1980;66:261-265.
20. Kamino H, Lee JY, Berke A. Pleomorphic fibroma of the skin: a benign neoplasm with cytologic atypia. A clinicopathologic study of eight cases. Am J Surg Pathol. 1989;13:107-113.
21. Karim RZ, Ma-Wyatt J, Cox M, et al. Myoid angioendothelioma of the spleen. Int J Surg Pathol. 2004;12:51-56.
22. Kraus MD. Splenic histology and histopathology: an update. Semin Diagn Pathol. 2003;20:84-93.
23. Kraus MD, Dehner LP. Benign vascular neoplasms of the spleen with myoid and angioendotheliomatous features. Histopathology. 1999;35: 328-336.
24. Kraus MD, Fleming MD, Vonderheide RH. The spleen as a diagnostic specimen: a review of 10 years' experience at two tertiary care institutions. Cancer. 2001;91:2001-2009.
25. Krishnan J, Frizzera G. Two splenic lesions in need of clarification: hamartoma and inflammatory pseudotumor. Semin Diagn Pathol. 2003; 20:94-104.
26. Lam KY, Yip KH, Peh WC. Splenic vascular lesions: unusual features and a review of the literature. Aust NZ J Surg. 1999;69:422-425.
27. Morgenstern L, McCafferty L, Rosenberg J, et al. Hamartomas of the spleen. Arch Surg. 1984;119:1291-1293.
28. Paterson A, Frush DP, Donnelly LF, et al. A pattern-oriented approach to splenic imaging in infants and children. Radiographics. 1999;19: 1465-1485.
29. Pinkus GS, Warhol MJ, O'Connor EM, et al. Immunohistochemical localization of smooth muscle myosin in human spleen, lymph node, and other lymphoid tissues: unique staining patterns in splenic white pulp and sinuses, lymphoid follicles, and certain vascularure, with ultrastrucrual correlations. Am J Pathol. 1986;123:440-453.
30. Ramani M, Reinhold C, Semelka RC, et al. Splenic hemangiomas and hamartomas: MR imaging characteristics of 28 lesions. Radiology. 1997; 202:166-172.
31. Rokitansky K. Ueber Tumoren, bestehend aus Lebertextur neuer Bildung. Allg wien Ztg. 1859:98-99.
32. Shmookler BM, Enzinger FM. Pleomorphic lipoma: a benign tumor simulating liposarcoma. A clinicopathologic analysis of 48 cases. Cancer. 1981;47:126-133.
33. Silverman ML, LiVolsi VA. Splenic hamartoma. Am J Clin Pathol. 1978; 70:224-229.
34. Singh K, Subbramaiah A, Choudhary SR, et al. Splenic hamartoma with portal hypertension: a case report. Trop Gastroenterol. 1992;13:155-159.
35. Tamada S, Ackerman AB. Dermatofibroma with monster cells. Am J Dermatopathol. 1987;9:380-387.
36. Toccanier-Pelte M-F, Skalli O, Kapanci Y. et al. Characterization of stromal cells with myoid features in lymph nodes and spleen in normal and pathologic conditions. Am J Pathol. 1987;129:109-118.
37. Young RH. Fibroepithelial polyp of the bladder with atypical stromal cells. Arch Pathol Lab Med. 1986;110:241-242.
38. Zukerberg LR, Kaynor BL, Silverman ML, et al. Splenic hamartoma and capillary hemangioma are distinct entities: immunohistochemical analysis of CD8 expression by endothelial cells. Hum Pathol. 1991;22: 1258-1261.